Cardiovascular effects caused by increasing concentrations of diesel exhaust in middle-aged healthy GSTM1 null human volunteers

References

• Allen J, Trenga CA, Peretz A, et al. (2009). Effect of diesel exhaust inhalation on antioxidant and oxidative stress responses in adults with metabolic syndrome. Inhal Toxicol 21:1061–7
   PubMed Web of Science ®Google Scholar
• Behndig AF, Larsson N, Brown JL, et al. (2011). Proinflammatory doses of diesel exhaust in healthy subjects fail to elicit equivalent or augmented airway inflammation in subjects with asthma. Thorax 66:12–19
   PubMed Web of Science ®Google Scholar
• Behndig AF, Mudway IS, Brown JL, et al. (2006). Airway antioxidant and inflammatory responses to diesel exhaust exposure in healthy humans. Eur Respir J 27:359–65
   PubMed Web of Science ®Google Scholar
• Brook RD, Brook JR, Urch B, et al. (2002). Inhalation of fine particulate air pollution and ozone causes acute arterial vasoconstriction in healthy adults. Circulation 105:1534–6
   PubMed Web of Science ®Google Scholar
• Brook RD, Urch B, Dvonch JT, et al. (2009). Insights into the mechanisms and mediators of the effects of air pollution exposure on blood pressure and vascular function in healthy humans. Hypertension 54:659–67
   PubMed Web of Science ®Google Scholar
• Carlsten C, Kaufman JD, Peretz A, et al. (2007). Coagulation markers in healthy human subjects exposed to diesel exhaust. Thromb Res 120:849–55
   PubMed Web of Science ®Google Scholar
• Carlsten C, Kaufman JD, Trenga CA, et al. (2008). Thrombotic markers in metabolic syndrome subjects exposed to diesel exhaust. Inhal Toxicol 20:917–21
   PubMed Web of Science ®Google Scholar
• Cosselman KE, Krishnan RM, Oron AP, et al. (2012). Blood pressure response to controlled diesel exhaust exposure in human subjects. Hypertension 59:943–8
   PubMed Web of Science ®Google Scholar
• Devlin RB, Ghio AJ, Kehrl H, et al. (2003). Elderly humans exposed to concentrated air pollution particles have decreased heart rate variability. Eur Respir J Suppl 40:76s–80s
   PubMedGoogle Scholar
• EPA. (2009). US EPA. Integrated science assessment for particulate matter (Final Report). Washington, DC: U.S. Environmental Protection Agency
   Google Scholar
• Ghelfi E, Wellenius GA, Lawrence J, et al. (2010). Cardiac oxidative stress and dysfunction by fine concentrated ambient particles (CAPs) are mediated by angiotensin-II. Inhal Toxicol 22:963–72
   PubMed Web of Science ®Google Scholar
• Ghio AJ, Carraway MS, Madden MC. (2012). Composition of air pollution particles and oxidative stress in cells, tissues, and living systems. J Toxicol Environ Health B Crit Rev 15:1–21
   PubMed Web of Science ®Google Scholar
• Gilliland FD, Li YF, Dubeau L, et al. (2002). Effects of glutathione S-transferase M1, maternal smoking during pregnancy, and environmental tobacco smoke on asthma and wheezing in children. Am J Respir Crit Care Med 166:457–63
   PubMed Web of Science ®Google Scholar
• Gold DR, Litonjua A, Schwartz J, et al. (2000). Ambient pollution and heart rate variability. Circulation 101:1267–73
   PubMed Web of Science ®Google Scholar
• Gong H, Linn WS, Terrell SL, et al. (2004). Exposures of elderly volunteers with and without chronic obstructive pulmonary disease (COPD) to concentrated ambient fine particulate pollution. Inhal Toxicol 16:731–44
   PubMed Web of Science ®Google Scholar
• Huang YC, Rappold AG, Graff DW, et al. (2012). Synergistic effects of exposure to concentrated ambient fine pollution particles and nitrogen dioxide in humans. Inhal Toxicol 24:790–7
   PubMed Web of Science ®Google Scholar
• Langrish JP, Lundback M, Mills NL, et al. (2009). Contribution of endothelin 1 to the vascular effects of diesel exhaust inhalation in humans. Hypertension 54:910–15
   PubMed Web of Science ®Google Scholar
• Lucking AJ, Lundback M, Barath SL, et al. (2011). Particle traps prevent adverse vascular and prothrombotic effects of diesel engine exhaust inhalation in men. Circulation 123:1721–8
   PubMed Web of Science ®Google Scholar
• Lundback M, Mills NL, Lucking A, et al. (2009). Experimental exposure to diesel exhaust increases arterial stiffness in man. Part Fibre Toxicol 6:7
   PubMed Web of Science ®Google Scholar
• Madden MC. (2008). Complex issues with examining diesel exhaust toxicity: is the task getting easier or harder? Exp Toxicol Pathol 60:135–40
   PubMed Web of Science ®Google Scholar
• McDonald JD, Campen MJ, Harrod KS, et al. (2011). Engine-operating load influences diesel exhaust composition and cardiopulmonary and immune responses. Environ Health Perspect 119:1136–41
   PubMed Web of Science ®Google Scholar
• Metassan S, Routledge MN, Lucking AJ, et al. (2010). Fibrin clot structure remains unaffected in young, healthy individuals after transient exposure to diesel exhaust. Part Fibre Toxicol 7:17
   PubMed Web of Science ®Google Scholar
• Mills NL, Finlayson AE, Gonzalez MC, et al. (2011a). Diesel exhaust inhalation does not affect heart rhythm or heart rate variability. Heart 97:544–50
   PubMed Web of Science ®Google Scholar
• Mills NL, Miller MR, Lucking AJ, et al. (2011b). Combustion-derived nanoparticulate induces the adverse vascular effects of diesel exhaust inhalation. Eur Heart J 32:2660–71
   PubMed Web of Science ®Google Scholar
• Mills NL, Tornqvist H, Gonzalez MC, et al. (2007). Ischemic and thrombotic effects of dilute diesel-exhaust inhalation in men with coronary heart disease. N Engl J Med 357:1075–82
   PubMed Web of Science ®Google Scholar
• Mills NL, Tornqvist H, Robinson SD, et al. (2005). Diesel exhaust inhalation causes vascular dysfunction and impaired endogenous fibrinolysis. Circulation 112:3930–6
   PubMed Web of Science ®Google Scholar
• Nightingale JA, Maggs R, Cullinan P, et al. (2000). Airway inflammation after controlled exposure to diesel exhaust particulates. Am J Respir Crit Care Med 162:161–6
   PubMed Web of Science ®Google Scholar
• Norskov MS, Frikke-Schmidt R, Loft S, et al. (2011). Copy number variation in glutathione S-transferases M1 and T1 and ischemic vascular disease: four studies and meta-analyses. Circ Cardiovasc Genet 4:418–28
   PubMed Web of Science ®Google Scholar
• Peretz A, Kaufman JD, Trenga CA, et al. (2008a). Effects of diesel exhaust inhalation on heart rate variability in human volunteers. Environ Res 107:178–84
   PubMed Web of Science ®Google Scholar
• Peretz A, Sullivan JH, Leotta DF, et al. (2008b). Diesel exhaust inhalation elicits acute vasoconstriction in vivo. Environ Health Perspect 116:937–42
   PubMed Web of Science ®Google Scholar
• Pope CA 3rd, Hansen ML, Long RW, et al. (2004). Ambient particulate air pollution, heart rate variability, and blood markers of inflammation in a panel of elderly subjects. Environ Health Perspect 112:339–45
   PubMed Web of Science ®Google Scholar
• Salvi S, Blomberg A, Rudell B, et al. (1999). Acute inflammatory responses in the airways and peripheral blood after short-term exposure to diesel exhaust in healthy human volunteers. Am J Respir Crit Care Med 159:702–9
   PubMed Web of Science ®Google Scholar
• Samet JM, Rappold A, Graff D, et al. (2009). Concentrated ambient ultrafine particle exposure induces cardiac changes in young healthy volunteers. Am J Respir Crit Care Med 179:1034–42
   PubMed Web of Science ®Google Scholar
• Sawant AA, Cocker DR 3rd, Miller JW, et al. (2008). Generation and characterization of diesel exhaust in a facility for controlled human exposures. J Air Waste Manag Assoc 58:829–37
   PubMedGoogle Scholar
• Schneider A, Neas L, Herbst MC, et al. (2008). Endothelial dysfunction: associations with exposure to ambient fine particles in diabetic individuals. Environ Health Perspect 116:1666–74
   PubMed Web of Science ®Google Scholar
• Sobus JR, Pleil JD, Madden MC, et al. (2008). Identification of surrogate measures of diesel exhaust exposure in a controlled chamber study. Environ Sci Technol 42:8822–8
   PubMed Web of Science ®Google Scholar
• Tornqvist H, Mills NL, Gonzalez M, et al. (2007). Persistent endothelial dysfunction in humans after diesel exhaust inhalation. Am J Respir Crit Care Med 176:395–400
   PubMed Web of Science ®Google Scholar
• Urch B, Silverman F, Corey P, et al. (2005). Acute blood pressure responses in healthy adults during controlled air pollution exposures. Environ Health Perspect 113:1052–5
   PubMed Web of Science ®Google Scholar
• Wu W, Peden D, Diaz-Sanchez D. (2012). Role of GSTM1 in resistance to lung inflammation. Free Radic Biol Med 53:721–9
   PubMed Web of Science ®Google Scholar