Exposure to ozone induces a systemic inflammatory response: possible source of the neurological alterations induced by this gas

References

• Aris RM, Christian D, Hearne PQ, et al. (1993). Ozone-induced airway inflammation in human subjects as determined by airway lavage and biopsy. Am Rev Respir Dis 148:1363–72
   PubMed Web of Science ®Google Scholar
• Arito H, Uchiyama I, Yokoyama E. (1992). Acute effects of ozone on EEG activity, sleep-wakefulness and heart rate in rats. Ind Health 30:23–34
   PubMed Web of Science ®Google Scholar
• Arsalane K, Gosset P, Vanhee D, et al. (1995). Ozone stimulates synthesis of inflammatory cytokines by alveolar macrophages in vitro. Am J Respir Cell Mol Biol 13:60–8
   PubMed Web of Science ®Google Scholar
• Avila-Costa MR, Colín-Barenque L, Fortoul TI, et al. (1999). Memory deterioration in an oxidative stress model and its correlation with cytological changes on rat hippocampus CA1. Neurosci Lett 270:107–9
   PubMed Web of Science ®Google Scholar
• Banks WA. (2005). Blood-brain barrier transport of cytokines: a mechanism for neuropathology. Curr Pharm Des 11:973–84
   PubMed Web of Science ®Google Scholar
• Cho HY, Liu-Yi Z, Kleeberger SR. (2001). Ozone-induced lung inflammation and hyperreactivity are mediated via tumor necrosis factor-a receptors. Am J Physiol Lung Cell Mol Physiol 280:L537–46
   PubMed Web of Science ®Google Scholar
• Cho HY, Morgan DL, Bauer AK, Kleeberger SR. (2007). Signal transduction pathways of tumor necrosis factor-mediated lung injury induced by ozone in mice. Am J Respir Crit Care Med 175:829–39
   PubMed Web of Science ®Google Scholar
• Cottet-Emard JM, Dalmaz Y, Pequignot J, et al. (1997). Long-term exposure to ozone alters peripheral and central catecholamine activity in rats. Pflügers Arch-Eur J Physiol 433:744–9
   PubMed Web of Science ®Google Scholar
• Craig L, Brook JR, Chiotti Q, et al. (2008). Air pollution and public heatlh: a guidance document for risk managers. J Toxicol Environ Health A 71:588–698
   PubMed Web of Science ®Google Scholar
• Custodio V, González E, Rubio C, Paz C. (2010). Brain noradrenaline changes in rats prenatally exposed to ozone. Environ Toxicol Pharmacol 30:91–4
   Web of Science ®Google Scholar
• Dales RE, Cakmak S, Blanco-Vidal C. (2009). Air pollution and hospitalization for headache in Chile. Am J Epidemiol 170:1057–66
   PubMed Web of Science ®Google Scholar
• Dantzer R, Kelley KW. (2007). Twenty years of research on cytokine-induced sickness behavior. Brain Behav Immun 21:153–60
   PubMed Web of Science ®Google Scholar
• Devlin RB, McDonnel WF, Becker S, et al. (1996). Time-dependent changes of inflammatory mediators in the lungs of humans exposed to 0.4 ppm ozone for 2 hr: a comparison of mediators found in bronchoalveolar lavage fluid 1 and 18 hr efter exposure. Toxicol Appl Pharmacol 138:176–85
   PubMed Web of Science ®Google Scholar
• Dorado-Martínez C, Paredes-Carbajal C, Mascher D, et al. (2001). Effects of different ozone doses on memory, motor activity and lipid peroxidation levels in rats. Int J Neurosci 108:149–61
   PubMed Web of Science ®Google Scholar
• Genc S, Zadeoglulari Z, Fuss SH, Genc K. (2012). The adverse effects of air pollution on the nervous system. J Toxicol 2012:782462. doi: 10.1155/2012/782462
   PubMedGoogle Scholar
• González-Piña R, Paz C. (1997). Brain monoamine changes in rats after short periods of ozone exposure. Neurochem Res 22:63–6
   PubMed Web of Science ®Google Scholar
• Graham JA, Menzel DB, Miller FJ, et al. (1981). Influence of ozone on pentobarbital-induced sleeping time in mice, rats, and hamsters. Toxicol Appl Pharmacol 61:64–73
   PubMed Web of Science ®Google Scholar
• Haddad EB, Salmon M, Koto H, et al. (1996). Ozone induction of cytokine-induced neutrophil chemoattractant (CINC) and nuclear factor-kappa b in rat lung: inhibition by corticosteroids. FEBS Lett 379:265–8
   PubMed Web of Science ®Google Scholar
• Harkema JR, Wanger JG. (2005). Epithelial and inflammatory responses in the airways of laboratory rats coexposed to ozone and biogenic substances: enhancement of toxicant-induced airway injury. Exp Toxicol Pathol 57:129–41
   PubMedGoogle Scholar
• Haro R, Paz C. (1993). Effects of ozone exposure during pregnancy on ontogeny of sleep in rats. Neurosci Lett 164:67–70
   PubMed Web of Science ®Google Scholar
• Hatch GE, Slade R, Harris LP, et al. (1994). Ozone dose and effect in humans and rats. A comparison using oxygen-18 labelling and bronchoalveolar lavage. Am J Respir Crit Care Med 150:676–83
   PubMed Web of Science ®Google Scholar
• Huitrón-Reséndiz S, Custodio-Ramírez V, Escalante-Membrillo C, et al. (1994). Sleep alterations and brain regional changes of serotonin and its metabolite in rats exposed to ozone. Neurosci Lett 177:119–22
   PubMed Web of Science ®Google Scholar
• Ibrahim AD, Birmingham NP, Lewandowski R, et al. (2010). Acute exposure to ozone exacerbates acetaminophen-induced liver injury in mice. Toxicol Sci 115:267–85
   PubMed Web of Science ®Google Scholar
• Kari F, Hatch G, Slade R, et al. (1997). Dietary restriction mitigates ozone-induced lung inflammation in rats: a role for endogenous antioxidants. Am J Respir Cell Mol Biol 17:740–7
   PubMed Web of Science ®Google Scholar
• Kavlock RJ, Datson G, Grabowski CT. (1979). Studies on the developmental toxicity of ozone: I. prenatal effects. Toxicol Appl Pharmacol 48:19–28
   PubMed Web of Science ®Google Scholar
• Kavlock RJ, Meyer E, Grabowski CT. (1980). Studies in the developmental toxicity of ozone: postnatal effects. Toxicol Lett 5:3–9
   PubMed Web of Science ®Google Scholar
• Krueger JM. (2009). The role of cytokines in sleep regulation. Curr Pharm Des 14:3408–16
   Web of Science ®Google Scholar
• Manzer R, Dinarello CA, McConville G, Mason RJ. (2008). Ozone exposure of macrophages induces an alveolar epithelial chemokine response through IL-1{alpha}. Am J Respir Cell Mol Biol 38:318–23
   PubMed Web of Science ®Google Scholar
• Martínez-Lazcano JC, González-Guevara E, Rubio MC, et al. (2013). The effects of ozone exposure and associated injury mechanisms on the central nervous system. Rev Neurosci 24:337–52
   PubMed Web of Science ®Google Scholar
• Medzhitov R. (2008). Origin and physiological roles of inflammation. Nature 454:428–35
   PubMed Web of Science ®Google Scholar
• Mills NL, Donaldson K, Hadoke PW, et al. (2009). Adverse cardiovascular effects of air pollution. Nat Clin Pract Cardiovasc Med 6:36–44
   PubMedGoogle Scholar
• Narayan KM, Ali MK, Koplan JP. (2010). Global noncommunicable diseases – where worlds meet. N Engl J Med 363:1196–8
   PubMed Web of Science ®Google Scholar
• Nichols BG, Woods JS, Luchtel DL, et al. (2001). Effects of ozone exposure on nuclear factor-kappaB activation and tumor necrosis factor-alpha expression in human nasal epithelial cells. Toxicol Sci 60:356–62
   PubMed Web of Science ®Google Scholar
• Okada S, Nakamura M, Katoh H, et al. (2006). Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury. Nat Med 12:829–34
   PubMed Web of Science ®Google Scholar
• Pahl HL. (1999). Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 18:6853–66
   PubMed Web of Science ®Google Scholar
• Paz C, Bazán-Perkins B. (1992). Sleep-wake disorganization in cats exposed to ozone. Neurosci Lett 140:270–2
   PubMed Web of Science ®Google Scholar
• Paz C, Huitrón-Reséndiz S. (1996). The effects of ozone exposure on the sleep-wake cycle and serotonin contents in the pons of the rat. Neurosci Lett 204:49–52
   PubMed Web of Science ®Google Scholar
• Pryor WA, Squadrito GL, Friedman MA. (1995a). The cascade mechanism to explain ozone toxicity: the role of lipid ozonation products. Free Radic Biol Med 19:935–41
   PubMed Web of Science ®Google Scholar
• Pryor WA, Squadrito GL, Friedman M. (1995b). A new mechanism for the toxicity of ozone. Toxicology Lett 82:287–93
   PubMed Web of Science ®Google Scholar
• Rivas-Arancibia S, Dorado-Martínez C, Colin-Barenque L, et al. (2003). Effect of acute ozone exposure on locomotor behavior and striatal function. Pharmacol Biochem Behav 74:891–900
   PubMed Web of Science ®Google Scholar
• Rivas-Manzano P, Paz C. (1999). Cerebella morphological alterations in rats induced by prenatal ozone exposure. Neurosci Lett 276:37–40
   PubMed Web of Science ®Google Scholar
• Rubio C, Paz C. (2003). Indomethacin reverts sleep disorders produced by ozone exposure in rats. Toxicology 191:89–96
   PubMed Web of Science ®Google Scholar
• Slade R, Crissman K, Norwood J, Hatch G. (1993). Comparison of antioxidant substances in bronchoalveolar lavage cells and fluid from humans, guinea pigs, and rats. Exp Lung Res 19:469–84
   PubMed Web of Science ®Google Scholar
• Song H, Tan W, Zhang X. (2011). Ozone induces inflammation in bronchial epithelial cells. J Asthma 48:79–83
   PubMed Web of Science ®Google Scholar
• Sorace A, De Acetis L, Alleva E, Santucci D. (2001). Prolonged exposure to low doses of ozone: short- and long-term changes in behavioral performance in mice. Environ Res A 85:122–34
   PubMed Web of Science ®Google Scholar
• Stein B, Coswell PC, Baldwin AS. (1993). Functional and physical associations between NF-κB and C/EBP family members: a Rel domain-bZIP interaction. Mol Cell Biol 13:3964–74
   PubMed Web of Science ®Google Scholar
• Sticozzi C, Belmonte G, Meine A, et al. (2013). IL-1β induces GFAP expression in vitro and in vivo and protects neurons from traumatic injury-associated apoptosis in rat brain striatum via NFkB/Ca2+-calmodulin/ERK mitogen-activated protein kinase signaling pathway. Neuroscience 252:367–83
   PubMed Web of Science ®Google Scholar
• Takahashi S, Kapás L, Fang J, et al. (1996). An interleukin-1 receptor fragment inhibits spontaneous sleep and muramyl dipeptide-induced sleep in rabbits. Am J Physiol Regul Integr Comp Physiol 271:R101–8
   Web of Science ®Google Scholar
• Tanabe K, Matsushima N, Yamaguchi S, et al. (2010). Mechanisms of tumor necrosis factor-alpha-induced interleukin-6 synthesis in glioma cells. J Neuroinflammation 7:16–24
   PubMed Web of Science ®Google Scholar
• Tarrant JM. (2010). Blood cytokines as biomarkers of in vivo toxicity in preclinical safety assessment: considerations for their use. Toxicol Sci 117:4–16
   PubMed Web of Science ®Google Scholar
• Tepper JL, Weiss B, Cox C. (1982). Microanalysis of ozone depression of motor activity. Toxicol Appl Pharmacol 64:317–26
   PubMed Web of Science ®Google Scholar
• Winquist A, Klein M, Tolbert P, et al. (2012). Comparison of emergency department and hospital admissions data for air pollution time-series studies. Environ Health 11:70–83
   PubMed Web of Science ®Google Scholar
• World Health Organization. (2005). WHO Air quality guidelines for particulate matter, ozone, nitrogen dioxide and sulfur dioxide. Global update 2005. Summary of risk assessment. Available at: http://whqlibdoc.who.int/hq/2006/WHO_SDE_PHE_OEH_06.02_eng.pdf. [Last accessed: 10 Apr 2014]
   Google Scholar
• Yamaguchi S, Tanabe K, Takai S, et al. (2009). Involvement of Rho-kinase in tumor necrosis factor-alpha-induced interleukin-6 release from C6 glioma cells. Neurochem Int 55:438–45
   PubMed Web of Science ®Google Scholar