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Inhalation Toxicology
International Forum for Respiratory Research
Volume 28, 2016 - Issue 4
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Research Article

Subacute inhalation exposure to ozone induces systemic inflammation but not insulin resistance in a diabetic mouse model

Zhekang YingDepartment of Medicine, Cardiology Division, University of Maryland School of Medicine, Baltimore, MD, USA, Correspondence[email protected]
,
Katryn AllenDepartment of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, MH, USA, and
,
Jixin ZhongDepartment of Medicine, Cardiology Division, University of Maryland School of Medicine, Baltimore, MD, USA,
,
Minjie ChenDepartment of Medicine, Cardiology Division, University of Maryland School of Medicine, Baltimore, MD, USA,
,
Keisha M. WilliamsDepartment of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, MH, USA, and
,
James G. WagnerDepartment of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, MH, USA, and
,
Ryan LewandowskiDepartment of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, MH, USA, and
,
Qinghua SunCollege of Public Health, Ohio State University, Columbus, OH, USA
,
Sanjay RajagopalanDepartment of Medicine, Cardiology Division, University of Maryland School of Medicine, Baltimore, MD, USA,
&
Jack R. HarkemaDepartment of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, MH, USA, and
show all
Pages 155-163 | Received 10 Aug 2015, Accepted 22 Jan 2016, Published online: 17 Mar 2016

References

  • Alexeeff SE, Litonjua AA, Suh H, et al. (2007). Ozone exposure and lung function: effect modified by obesity and airways hyperresponsiveness in the VA normative aging study. Chest 132:1890–7
  • Bass V, Gordon CJ, Jarema KA, et al. (2013). Ozone induces glucose intolerance and systemic metabolic effects in young and aged Brown Norway rats. Toxicol Appl Pharmacol 273:551–60
  • Bennett WD, Hazucha MJ, Folinsbee LJ, et al. (2007). Acute pulmonary function response to ozone in young adults as a function of body mass index. Inhal Toxicol 19:1147–54
  • Chiu HF, Yang CY. (2009). Air pollution and emergency room visits for arrhythmias: are there potentially sensitive groups? J Toxicol Environ Health A 72:817–23
  • Cottet-Emard JM, Dalmaz Y, Pequignot J, et al. (1997). Long-term exposure to ozone alters peripheral and central catecholamine activity in rats. Pflugers Arch 433:744–9
  • Dales RE, Cakmak S, Vidal CB, Rubio MA. (2012). Air pollution and hospitalization for acute complications of diabetes in Chile. Environ Int 46:1–5
  • Devlin RB, Duncan KE, Jardim M, et al. (2012). Controlled exposure of healthy young volunteers to ozone causes cardiovascular effects. Circulation 126:104–11
  • Goldberg MS, Burnett RT, Stieb DM, et al. (2013). Associations between ambient air pollution and daily mortality among elderly persons in Montreal, Quebec. Sci Total Environ 463–464:931–42
  • Hollingsworth JW, Kleeberger SR, Foster W M. (2007). Ozone and pulmonary innate immunity. Proc Am Thorac Soc 4:240–6
  • Iwatsuka H, Shino A, Suzuoki Z. (1970). General survey of diabetic features of yellow KK mice. Endocrinol Jpn 17:23–35
  • Johnston RA, Theman T, Lu FL, et al. (2008). Diet-induced obesity causes innate airway hyperresponsiveness to methacholine and enhances ozone-induced pulmonary inflammation. J Appl Physiol 104:1727–35
  • Johnston RA, Theman TA, Shore SA. (2006). Augmented responses to ozone in obese carboxypeptidase E-deficient mice. Am J Physiol Regul Integr Comp Physiol 290:R126–33
  • Johnston RA, Theman TA, Terry RD, et al. (2007). Pulmonary responses to acute ozone exposure in fasted mice: effect of leptin administration. J Appl Physiol 102:149–56
  • Kim JH, Hong YC. (2012). GSTM1, GSTT1, and GSTP1 polymorphisms and associations between air pollutants and markers of insulin resistance in elderly Koreans. Environ Health Perspect 120:1378–84
  • Lee IM, Tsai SS, Ho CK, et al. (2008). Air pollution and hospital admissions for congestive heart failure: are there potentially sensitive groups? Environ Res 108:348–53
  • Liu C, Ying Z, Harkema J, et al. (2013). Epidemiological and experimental links between air pollution and type 2 diabetes. Toxicol Pathol 41:361–73
  • Moon HS, Dalamaga M, Kim SY, et al. (2013). Leptin's role in lipodystrophic and nonlipodystrophic insulin-resistant and diabetic individuals. Endocr Rev 34:377–412
  • Saravanan S, Pari L. (2015). Role of thymol on hyperglycemia and hyperlipidemia in high fat diet-induced type 2 diabetic C57BL/6J mice. Eur J Pharmacol 761:279–87
  • Shore SA. (2007). Obesity and asthma: lessons from animal models. J Appl Physiol 102:516–28
  • Shore SA, Lang JE, Kasahara DI, et al. (2009). Pulmonary responses to subacute ozone exposure in obese vs. lean mice. J Appl Physiol 107:1445–52
  • Shore SA, Rivera-Sanchez YM, Schwartzman IN, Johnston RA. (2003). Responses to ozone are increased in obese mice. J Appl Physiol 95:938–45
  • Shore SA, Williams ES, Zhu M. (2008). No effect of metformin on the innate airway hyperresponsiveness and increased responses to ozone observed in obese mice. J Appl Physiol 105:1127–33
  • Shulman GI. (2014). Ectopic fat in insulin resistance, dyslipidemia, and cardiometabolic disease. N Engl J Med 371:1131–41
  • Stafoggia M, Forastiere F, Faustini A, et al. (2010). Susceptibility factors to ozone-related mortality: a population-based case-crossover analysis. Am J Respir Crit Care Med 182:376–84
  • Tolbert PE, Klein M, Peel JL, et al. (2007). Multipollutant modeling issues in a study of ambient air quality and emergency department visits in Atlanta. J Expo Sci Environ Epidemiol 17:S29–35
  • Vella RE, Pillon NJ, Zarrouki B, et al. (2015). Ozone exposure triggers insulin resistance through muscle c-Jun N-terminal Kinases (JNKs) activation. Diabetes 64:1011–24
  • White CW, Martin J G. (2010). Chlorine gas inhalation: human clinical evidence of toxicity and experience in animal models. Proc Am Thorac Soc 7:257–63
  • Zanobetti A, Schwartz J. (2008). Is there adaptation in the ozone mortality relationship: a multi-city case-crossover analysis. Environ Health 7:22
  • Zanobetti A, Schwartz J. (2011). Ozone and survival in four cohorts with potentially predisposing diseases. Am J Respir Crit Care Med 184:836–41

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