Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 1, 1989 - Issue 4
8
Views
6
CrossRef citations to date
0
Altmetric
Research Article

Antioxidant Effects of α-Tocopherol and Ascorbate in Liposomes Exposed to Nitrogen Dioxide

, &
Pages 315-329 | Received 25 Mar 1989, Accepted 17 Jun 1989, Published online: 27 Sep 2008

References

  • Diliberto E. I., Jr, Heckman G. D., Daniels A. J. Characterization of ascorbic acid transport by adrenomedullary chromaffin cells. J. Biol. Chem. 1983; 258: 12886
  • Elsayed N. M., Mustafa M. G. Dietary antioxidants and the biochemical response to oxidant inhalaton: II. Influence of dietary vitamin E on the biochemical effects of nitrogen dioxide in rat lung. Toxicol. Appl. Pharmacol. 1982; 60: 319
  • Evans M. J., Cabral-Anderson L. J., Dekker N. P., Freeman G. The effects of dietary antiox-idants on NO2-induced injury to type I alveolar cells. Chest 1980; 80: 55
  • Gnehm H. E., Ackermann U., Braun C., Rutishauser M., Wanner H. U. Significant association of respiratory symptoms in small children with outdoor NO2 air pollution (abstr.). Pediatr. Res. 1988; 23: 291A
  • Hatch G. E., Slade R., Selgrade M. K., Stead A. G. Nitrogen dioxide exposure and lung antioxidants in ascorbic aciddeficient guinea pigs. Toxicol. Appl. Pharmacol. 1986; 82: 351
  • Hruba F., Novakova V., Ginter E. The effect of chronic marginal vitamin C deficiency on the α-tocopherol content of the organs and plasma of guinea pigs. Experientia 1982; 38: 1454
  • Kanazawa K., Takeuchi S., Hasegawa R., Okada M., Makiyama I., Hirose N., Toh T., Cho S.-H., Kobayashi M. Influence of ascorbic acid deficiency on the level of non-protein SH compounds and vitamin E in the blood and tissues of guinea pigs. Nihon Univ. J. Med. 1981; 23: 257
  • Krishnamurthy S., Bieri J. G. The absorption, storage, and metabolism of α-tocopherol-14C in the rat and chicken. J. Lipid Res. 1963; 4: 330
  • Lee Y.-N., Schwartz S. E. Reaction kinetics of nitrogen dioxide with liquid water at low partial pressure. J. Phys. Chem. 1981; 85: 840
  • Liebler D. C., Kling D. S., Reed D. J. Prooxidant and antioxidant effects of glutathione and ascorbic acid on Fe2+/H2O2-induced peroxidation of liposomes containing α-tocopherol. Toxicologist 1986; 6: 151
  • Lowenstein J. D., Wolmark Y., Bourdel M. C., Maffiolo C., Kraimik F., Ferette B., Berthaux P. Etude longitudinale sur les relations enter les conditions d'environment et la sante des pensionnaires d'un hopital de long sejour. [Relation of environmental conditions to the health of the elderly in a long-term care hospital: A longitudinal survey.]. Rev. Epidemiol Sante Publ. 1985; 33: 262
  • McCay P. B., Poyer J. L., Pfeifer P. M., May H. E., Gilliam J. M. A function for α-tocopherol: Stabilization of the microsomal membrane from radical attack during TPNH-dependent oxidations. Lipids 1971; 6: 297
  • Mead J. F., Can-Elepano M., Hirahara F. Initiation of peroxidation by nitrogen dioxide in natural and model membrane systems. Nitrogen Oxides and Their Effects on Health, S. D. Lee. Ann Arbor Science., Ann Arbor, Mich. 1980; 191
  • Menzel D. B. Toxicity of ozone, oxygen, and radiation. Annu. Rev. Pharmacol. 1970; 10: 379
  • Menzel D. B., Roehm J. N., Lee S. D. Vitamin E: The environmental and biological antioxidant. J. Agric. Food Chem. 1972; 20: 481
  • Mimms L. T., Zampighi G., Nozaki Y., Tanford C., Reynolds J. A. Phospholipid vesicle formation and transmembrane protein incorporation using octyl glucoside. Biochemistry 1981; 20: 833
  • Molenaar I., Hommes F. A., Braams W. G., Polman H. A. Effect of vitamin E on membranes of the intestinal cell. Proc. Natl. Acad. Sci. U.S.A 1968; 61: 982
  • Mustafa M. G., Tierney D. F. Biochemical and metabolic changes in the lung with oxygen, ozone, and nitrogen dioxide toxicity. Annu. Rev. Respir: Dis. 1978; 118: 1061
  • Overton H. H., Graham R. C., Miller F. J. A model of the regional uptake of gaseous pollutants in the lung. Toxicol. Appl. Pharmacol. 1987; 88: 418
  • Rao G. H., Krick T. P., White J. G. Preparation, separation and characterization of vitamin E quinone. J. Chromatog. 1980; 196: 506
  • Roehm J. N., Hadley J. G., Menzel D. B. Antioxidants vs. lung disease. Arch. Intern. Med. 1971a; 128: 88
  • Roehm J. N., Hadley J. G., Menzel D. B. Oxidation of unsaturated fatty acids by ozone and nitrogen dioxide—Acommon mechanism of action. Arch. Environ. Health 1971b; 23: 142
  • Sevanian A., Elsayed N., Hacker A. D. Effects of vitamin E deficiency and nitrogen dioxide exposure on lung lipid peroxidation: Use of lipid epoxides and malondialdehyde as measures of peroxidation. J. Toxicol. Environ. Health 1982; 10: 743
  • Shenstone F. S. Ultraviolet and visible spectroscopy of lipids. Biochemistry and Methodology of Lipids, A. R. Johnson, J. B. Davenport. Wiley, New York 1966; 219, -lnterscience
  • Shoaf C. R., Wolpert R. L., Menzel D. B. Nitrogen dioxide-initiated peroxidation of liposomal membrane systems. Inhal. roxicol. 1989; 1: 301–314
  • Skoa F., Jr. Comparative properties and methods of preparation of lipid vesicles (liposomes). Annu. Rev. Biophys. Bioeng. 1980; 9: 467
  • Tappel A. L. Vitamin E as the biological lipid antioxidant. Vitamins and Hormones, R. S. Harris, I. G. Wool, C. S. Marriam, K. V. Thimann. Academic Press, New York 1962; vol. 20: 493
  • Tappel A. L. Will antioxidant nutrients slow aging processes?. Geriatrics 1968; 23: 97
  • Thomas H. V., Mueller P. K., Lyman R. L. Lipoperoxidation of lung lipids in rats exposed to nitrogen dioxide. Science 1967; 159: 532

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.