Gas Uptake Inhalation Techniques and the Rates of Metabolism of Chloromethanes, Chloroethanes, and Chloroethylenes in the Rat

References

• Anders M. W., Pohl L. R. Halogenated alkanes. Bioactivation of Foreign Compounds, M. W. Anders. Academic Press, New York 1985; 283–315
   Google Scholar
• Andersen M. E., Gargas M. L., Jones R. A., Jenkins L. J., Jr. The use of inhalation techniques to assess the kinetic constants of 1, 1-dichloroethylene metabolism. Toxicol. Appl. Pharmacol. 1979; 47: 395–409
   PubMed Web of Science ®Google Scholar
• Andersen M. E., Gargas M. L., Clewell H. J., III. Suicide inactivation of microsomal oxidation by cis- and transdichloroethylene (C-DCE and T-DCE) in male Fischer rats. in vivo. Toxicologist 1986a; 6, abstr
   Google Scholar
• Andersen M. E., Clewell H. I., III, Gargas M. L., Conolly R. B. A physiological pharma-cokinetic model for hepatic glutathione (CSH) depletion of inhaled halogenated hydrocarbons. Toxicologist 1986b; 6, abstr. 596
   Google Scholar
• Andersen M. E., Clewell H. J., III, Gargas M. L., Smith F. A., Reitz R. H. Physiologically-based pharmacokinetics and the risk assessment process for methylene chloride. Toxicol. Appl. Pharmacol. 1987a; 87: 35–205
   Web of Science ®Google Scholar
• Andersen M. E., Gargas M. L., Clewell H. I., III, Severyn K. M. Quantatitive evaluation of the metabolic interactions between trichloroethylene and 1, 1-dichloroethylene in vivo using gas uptake methods. Toxicol. Appl. Pharmacol. 1987b; 89: 149–157
   PubMed Web of Science ®Google Scholar
• Clewell H. J., III, Andersen M. E. Dose, species, and route extrapolation using physiologically based pharmacokinetic models. Drinking Water and Health, Pharmacokinetics in Risk Assessment. National Academy Press, Washington, D.C. 1987; vol. 8: 159–182
   Google Scholar
• Clewell H. J., III, Andersen M. E., MacNaughton M. C., Stuart B. O. Toxicokinetics: An analytical tool for assessing chemical hazards to man. Aviat. Space Environ. Med. 1988; 59: A125–A131
   PubMedGoogle Scholar
• Costa A. K., Ivanetich K. M. The 1, 2dichloroethylenes: Their metabolism by hepatic cytochrome P-450 in vitro. Biochem. Pharmacol. 1982; 31: 2093–2102
   PubMed Web of Science ®Google Scholar
• Costa A. K., Ivanetich K. M. Chlorinated ethylenes: Their metabolism and effect on DNA repair in rat hepatocytes. Carcinogenesis 1984; 5: 1629–1636
   PubMed Web of Science ®Google Scholar
• D'Souza R. W., Andersen M. E. Physiologically based pharmacokinetic model for vinyli-dene chloride. Toxicol. Appl. Pharmacol. 1988; 95: 230–240
   PubMed Web of Science ®Google Scholar
• D'Souza R. W., Francis W. R., Bruce R. O., Andersen M. E. Physiologically-based pharmacokinetic model for ethylene dichloride and its application in risk assessment. Drinking Water and Health, Pharmacokinetics in Risk Assessment. National Academy Press, Washington, D.C. 1987; vol. 8: 286–301
   Google Scholar
• Filser J. G., Bolt H. M. Pharmacokinetics of halogenated ethylenes in rats. Arch. Toxicol. 1979; 42: 123–136
   PubMed Web of Science ®Google Scholar
• Gargas M. L., Andersen M. E. Physiologically-based approaches for examining the pharmacokinetics of inhaled vapors. Toxicology of the Lung, D. E. Gardner, J. D. Crapo, E. J. Massaro. Raven Press., New York 1988a; 449–476
   Google Scholar
• Gargas M. L., Andersen M. E. A gas phase technique for determining the kinetic constants of chemical metabolism in the rat. Toxicologist 1988b; 8, abstr 445
   Google Scholar
• Gargas M. L., Andersen M. E., Clewell H. I., III. A physiologically-based simulation approach for determining metabolic constants from gas uptake data. Toxicol. Appl. Pharmacol. 1986a; 86: 341–352
   PubMed Web of Science ®Google Scholar
• Gargas M. L., Clewell H. J., III, Andersen M. E. Metabolism of inhaled dihalomethanes in vivo: Differentiation of kinetic constants of two independent pathways. roxicol. Appl. Pharmacol. 1986b; 82: 211–223
   PubMed Web of Science ®Google Scholar
• Gargas M. L., Seybold P. G., Andersen M. E. Modeling the tissue solubilities and metabolic rate constant (Vmax) of halogenated methanes, ethanes, and ethylenes. Toxicol. Lett. 1988; 43: 235–256
   PubMed Web of Science ®Google Scholar
• Gargas M. L., Burgess R. J., Voisard D. E., Cason C. H., Andersen M. E. Partition coefficients of low molecular weight volatile chemicals in various liquids and tissues. Toxicol. Appl. Pharmacol. 1989; 98: 87–99
   PubMed Web of Science ®Google Scholar
• Henschler D. Halogenated alkenes and alkynes. Bioactivation of Foreign Compounds, M. W. Anders. Academic Press, New York 1985; 317–346
   Google Scholar
• Ivanetich K. M., Van Den Honert L. H. Chloroethanes: Their metabolism by hepatic cytochrorne P-450. in vitro. Carcinogenesis 1981; 2: 697–702
   PubMed Web of Science ®Google Scholar
• Kornbrust D. J., Bus J. S. Glutathione depletion by methyl chloride and association with lipid peroxidation in mice and rats. Toxicol. Appl. Pharmacol. 1984; 72: 388–399
   PubMed Web of Science ®Google Scholar
• Kubic V. L., Anders M. W. Metabolism of dihalomethanes to carbon monoxide. Ill. Studies on the mechanism of the reaction. Biochem. Pharrnacol. 1978; 27: 2349–2355
   PubMed Web of Science ®Google Scholar
• Mansuy D., Battioni P. Particular ability of cytochromes P-450 to form reactive intermediates and metabolites. Drug Metabolism, Molecular Approaches and Pharmacological Implications, G. Seist. Pergamon Press., New York 1985; 195–203
   Google Scholar
• McDougal J. N., Jepson G. W., Clewell H. J., III, MacNaughton M. G., Andersen M. E. A physiological pharmacokinetic model for dermal adsorption of vapors in the rat. Toxicol. Appl. Pharmacol. 1985; 85: 286–294
   Web of Science ®Google Scholar
• McDougal J. N., Jepson C. W., Clewell H. J., III, Gargas M. L., Andersen M. E. Dermal adsorption of organic chemical vapors in rats and humans. Fundam. Appl. Tox. 1990; 14: 299–308
   PubMedGoogle Scholar
• Paustenbach D. J., Clewell H. J., III, Gargas M. L., Andersen M. E. A physiologically-based pharmacokinetic model for inhaled carbon tetrachloride. Toxicol. Appl. Pharmacol. 1988; 96: 191–211
   PubMed Web of Science ®Google Scholar
• Ramsey J. C., Andersen M. E. A physiologically-based description of the inhalation pharmacokinetics of styrene monomer in rats and humans. Toxicol. Appl. Pharrnacol. 1984; 72: 159–175
   PubMed Web of Science ®Google Scholar
• Salmon A. G., Jones R. B., Mackrodt W. C. Microsomal dichlorination of chloroethanes: Structure-reactivity relationships. Xenobiotica 1981; 11: 723–734
   PubMed Web of Science ®Google Scholar