Age-Related Toxicity in Rat Lungs Following Acute and Repeated Ozone Exposure

References

• Avol E. L., Linn W. S., Venet T. C., Shamoo D. A., Hackney J. D. Comparative respiratory effects of ozone and ambient oxidant pollution exposure during heavy exercise. J. AirPollut. Control Assoc. 1984; 34: 804–809
   PubMed Web of Science ®Google Scholar
• Avol E. L., Linn W. S., Shamoo D. A., Valencia L. M., Anzar U. T., Venet T. G., Hackney J. D. Respiratory effects of photo chemical oxidant air pollution in exercising adolescents. Am. Rev. Respir. Dis. 1985; 132: 619–622
   PubMed Web of Science ®Google Scholar
• Avol E. L., Linn W. S., Shamoo D. A., Spier C. E., Valencia L. M., Venet T. C., Trim S. C., Hackney J. D. Short-term respiratory effects of photochemical oxidant exposure in exercising children. J. Air Pollut. Control Assoc. 1987; 37: 158–162
   Google Scholar
• Barry B. E., Miller F. J., Crapo J. D. Effects of inhalation of 0.12 and 0.25 ppm ozone on the proximal alveolar region of juvenile and adult rats. Lab. Invest. 1985; 53: 692–704
   PubMed Web of Science ®Google Scholar
• Barry B. E., Mercer R. R., Miller F. J., Crapo J. D. Effects of inhalation of 0.25 ppm ozone on the terminal bronchioles of juvenile and adult rats. Exp. Lung Res. 1988; 14: 225–245
   PubMed Web of Science ®Google Scholar
• Bedi J. F., Horvath S. M., Drechsler-Park D. M. Reproducibility of the pulmonary function response of older men and women to a 2-hour ozone exposure. J. Air Pollut. Control Assoc. 1988; 38: 1016–1019
   Google Scholar
• Bradford M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976; 72: 248–254
   PubMed Web of Science ®Google Scholar
• Burnett R. T., Dales R. E., Raizenne M. E., Krewski D., Summers P. W., Roberts G. R., Raad-Young M., Dann T., Brook J. Effects of low ambient levels of ozone and sulfates on the frequency of respiratory admissions to Ontario hospitals. Environ. Res. 1994; 65: 172–194
   PubMed Web of Science ®Google Scholar
• Collier C. G., Hodgson A., Gray S. A., Moody J. C., Ball A. The lung clearance kinetics of 57Co3O4 in rats of various ages. J. Aerosol Sci. 1991; 22(6)537–549
   Google Scholar
• Devlin R. B., McDonnell W. F., Mann R., Becker S., House D. E., Schrelnemachers D., Koren H. S. Exposure of humans to ambient levels of ozone for 6.6 hours causes cellular and biochemical changes in the lung. Am. J. Respir. Cell Mol. Biol. 1991; 4: 72–81
   PubMed Web of Science ®Google Scholar
• Dormans J. A. M. A. Application of the disector method in the light microscopic qualification of type II pneumocytes in control and ozone-exposed rats. J. Microsc. 1989; 155: 207–211
   PubMed Web of Science ®Google Scholar
• Doumas B. T., Briggs H. G. Determination of serum albumin. Standard methods of clinical chemistry, G. R. Cooper. Academic Press, New York 1972; vol. 7: 175–188
   Google Scholar
• Drechsler-Parks D. M., Bedi J. F., Horvath S. M. Pulmonary function responses of young and older adults to mixtures of O3, NO2 and PAN. Toxicol. Ind. Health 1989; 5(3)505–517
   PubMed Web of Science ®Google Scholar
• Dutch Society of Clinical Chemistry. Recommendations. Communications NVKC 1979; 4: 314–319
   Google Scholar
• Elsayed N. M., Mustafa M. G., Postlethwait E. M. Age-dependent pulmonary response of rats to ozone exposure. J. Toxicol. Environ. Health 1982; 9: 835–848
   PubMed Web of Science ®Google Scholar
• Folinsbee L. J., McDonnell W. F., Horstman D. H. Pulmonary function and symptom responses after 6.6 hour exposure to 0.12 ppm ozone with moderate exercise. J. Air Pollut. Control Assoc. 1988; 38: 28–35
   Google Scholar
• Folinsbee L. J., Horstman D. H., Kehrl H. R., Harder S., Abdul-Salaam S., Ives P. J. Respiratory responses to repeated prolonged exposures to 0.12 ppm ozone. Am. J. Respir. Crit. Care Med. 1994; 149: 98–105
   PubMed Web of Science ®Google Scholar
• Frischer T. M., Kuehr J., Pullwitt A., Meinert R., Forsler J., Studnicka M., Koren H. Ambient ozone causes upper airways inflammation in children. Am. Rev. Respir. Dis. 1993; 148: 961–964
   PubMed Web of Science ®Google Scholar
• Fukase O., Isomura K. Effects of exercise on mice exposed to ozone. Arch. Environ. Health 1978; 33: 198–200
   PubMed Web of Science ®Google Scholar
• Gunnison A. F., Weideman P. A., Sobo M., Koenig K. L., Chen L. C. Age-dependence of responses to acute ozone exposure in rats. Fundam. Appl. Toxicol. 1992; 18: 360–369
   PubMedGoogle Scholar
• Hacker A. D., Mustafa M. G., Ospital J. J., Elsayed N. M., Lee S. D. Relationship of age to rat lung collagen synthesis in response to ozone exposure. Age 1986; 9: 1–5
   Google Scholar
• Hoek G., Brunekreef B. Effects of photochemical air pollution on acute respiratory symptoms in children. Am. J. Respir. Crit. Care Med. 1995; 151: 27–32
   PubMed Web of Science ®Google Scholar
• Hoek G., Fischer P., Brunekreef B., Lebret E., Hofschreuder P., Mennen M. G. Acute effects of ambient ozone on pulmonary function in children in the Netherlands. Am. Rev. Respir. Dis. 1993; 147: 111–117
   PubMed Web of Science ®Google Scholar
• Koenig J. Q., Covert D. S., Marshall S. G., Van Belle G., Pierson W. E. The effects of ozone and nitrogen dioxide on pulmonary function in healthy and in asthmatic adolescents. Am. Rev. Respir. Dis. 1987; 136: 1152–1157
   PubMed Web of Science ®Google Scholar
• Koenig J. Q., Covert D. S., Smith M. S., Van Belle G., Pierson W. E. The pulmonary effects of ozone and nitrogen dioxide alone and combined in healthy and asthmatic adolescent subjects. Toxicol. Ind. Health 1988; 4: 521–532
   PubMed Web of Science ®Google Scholar
• Lawrence R. A., Burk R. F. Glutathione peroxidase activity in selenium-deficient rat liver. Biochem. Biophys. Res. Commun. 1976; 71: 952
   PubMed Web of Science ®Google Scholar
• Lipman J. M. Fluorophotometric quantitation of DNA in articular cartilage utilizing Hoechst 33258. Anal. Biochem. 1989; 176: 128–131
   PubMed Web of Science ®Google Scholar
• Lippmann M. Health effects of troposheric ozone: A review of recent findings and their implications to ambient air quality standards. J. Expos. Anal. Environ. Epidemiol. 1993; 3: 103–129
   PubMedGoogle Scholar
• Lunan K. D., Short P., Negi D., Stephens R. J. (1977) Glucose-6-phosphate dehydrogenase response of postnatal lungs lo NO2 and O3. Pulmonary macrophage and epithelial cells: Proceedings of the 16th Annual Hanford Biology Symposium, Richland, WA, Sept., 1976, C. L. Sanders, R. P. Schneider, G. E. Dagle, H. A. Ragan. Energy Research and Development Administration, Washington, DC, 236–247
   Google Scholar
• Marra M., Rombout P. J. A. Design and performance of an inhalation chamber for exposing laboratory animals to oxidant air pollutants. Inhal. Toxicol. 1990; 2: 187–204
   Google Scholar
• Matsuo M., Gomi F., Dooley M. M. Age-related alterations in antioxidant capacity and lipid peroxidation in brain, liver, and lung homogenates of normal and vitamin E-deficient rats. Mech. Ageing Dev. 1992; 64: 273–292
   PubMed Web of Science ®Google Scholar
• Mays P. K., McAnulty R. J., Laurent G. J. Age-related changes in collagen metabolism. A role for degradation in regulating lung collagen production. Am. Rev. Respir. Dis. 1989; 140: 410–416
   PubMed Web of Science ®Google Scholar
• McDonnell W. F. Intersubject variability in human acute ozone responses. Pharmacogenetics 1991; 1: 110–113
   PubMedGoogle Scholar
• McDonnell W. F., Chapman R. S., Leigh M. W., Strope C. L., Collier A. M. Respiratory responses of vigorously exercising children to 0.12 ppm ozone exposure. Am. Rev. Respir. Dis. 1985; 132: 875–879
   PubMed Web of Science ®Google Scholar
• Montgomery M. R., Raska-Emery P., Balis J. U. Recovery of lung pyridine nucleotides following acute exposure of adult and aged rats to ozone. J. Toxicol. Environ. Health 1991; 34: 115–126
   PubMed Web of Science ®Google Scholar
• Morgan K. T. Approaches to the identification and recording of nasal lesions in toxicology studies. Toxicol. Pathol. 1991; 19: 337–351
   PubMed Web of Science ®Google Scholar
• Mustafa M. C., Hacker A. D., Ospital J. J., Hussain M. Z., Lee S. D. Biochemical effects of environmental oxidant pollutants in animal lungs. Biochemical effects of environmental pollutants, S. D. Lee. Ann Arbor Science, Ann Arbor, MI 1977; 59
   Google Scholar
• Mustafa M. C., Elsayed N. M., Ospital J. J., Hacker A. D. Influence of age on the biochemical response of rat lung to ozone exposure. Toxicol. Ind. Health 1985; 1: 29–41
   PubMedGoogle Scholar
• Ospital J. J., Elsayed N. M., Mustafa M. C., Lee S. D. Influence of age on the effect of ozone exposure in rat lungs. Am. Rev. Respir. Dis. 1977; S1150: 235
   Google Scholar
• Perez R., Lopez M., Barja de Quiroga C. Aging and lung antioxidant enzymes glutathione and lipid peroxidation in the rat. Free Radical Biol. Med. 1991; 10: 35–39
   PubMed Web of Science ®Google Scholar
• Pinkerton K. E., Barry B. E., O'Neill J. J., Raub J. A., Pratt P. C., Crapo J. D. Morphological changes in the lung during the lifespan of Fischer 344 rats. Am. J. Anat. 1982; 164: 155–174
   PubMedGoogle Scholar
• Popp J. A., Monteiro-Riviere N. A. M. Macroscopic, microscopic and ultrastructural anatomy of the nasal cavity, rat. Respiratory system, T. C. Jones, U. Mohr, R. D. Hunt. Springer Verlag, Berlin 1985; 3–10
   Google Scholar
• Racker E. Glutathione reductase (liver and yeast). Methods in enzymology, S. P. Colowick, N. O. Kaplan. Academic Press, New York 1955; vol. 2: 722
   Google Scholar
• Rao G., Xia E., Richardson A. Effect of age on the expression of antioxidant enzymes in male Fischer F344 rats. Mech. Ageing Dev. 1990; 53: 49–60
   PubMed Web of Science ®Google Scholar
• Raska-Emery P., Balis J. U., Montgomery M. R. Effects of ozone on adult and aged lung oxygen consumption, glucose metabolism and G6PDH activity. Toxicologist 1991; 11(1)130
   Google Scholar
• Reisenauer C. S., Koenig J. Q, McManus M. S., Smith M. S., Kusic G., Pierson W. E. Pulmonary response to ozone exposures in healthy individuals aged 55 years or greater. J. Air Pollut. Control Assoc. 1988; 38: 51–55
   Google Scholar
• Reynolds H. Y., Thomson R. E. Pulmonary host defenses. II. Interaction of respiratory antibodies with Pseudomonas aeruginosa and alveolar macrophages. J. Immunol. 1973; 111: 369–380
   PubMed Web of Science ®Google Scholar
• Rietjens I. M. C. M., van Bree L., Marra M., Poelen M. C. M., Rombout P. J. A., Alink G. M. Glutathione pathway enzyme activities and the ozone sensitivity of lung cell populations derived from ozone exposed rats. Toxicology 1985; 37: 205–214
   PubMed Web of Science ®Google Scholar
• Ruitenberg E. J., Van Noorle Jansen L. M. Effect of Corynebacterium parvum on the course of a Listeria monocytogenes infection in normal and congenially athymic (nude) mice. Zbl. Bakt. Hyg. I. Abt. Orig. A 1975; 231: 197–205
   PubMedGoogle Scholar
• Ruitenberg E. J., Van Noorle Jansen L. M., Kruizinga W., Steerenberg P. A. Effect of pretreatment with Bacille Calmette Guerin on the course of a Listeria monocytogenes infection in normal and congenially athymic (nude) mice. Br. J. Exp. Pathol. 1976; 57: 310–315
   PubMedGoogle Scholar
• Sahebjami H. Lung tissue elasticity during the lifespan of Fischer 344 rats. Exp. Lung Res. 1991; 17: 887–902
   PubMed Web of Science ®Google Scholar
• Schwartz L. W., Dungworth D. L., Mustafa M. G., Tarkington B. K., Tyler W. S. Pulmonary responses of rats to ambient levels of ozone. Lab. Invest. 1976; 34: 565–578
   PubMed Web of Science ®Google Scholar
• Seal E., McDonnell W. F., Chapman R. S., House D. E. The effect of menstrual cycle and age on the pulmonary response to ozone. Am. Rev. Respir. Dis. 1993; 147: A637
   Google Scholar
• Sohal R. S., Arnold L. A., Sohal B. H. Age-related changes in antioxidant enzymes and prooxidant generation in tissues of the rat with special reference to parameters in two insect species. Free Radical Biol. Med. 1990; 10: 495–500
   Google Scholar
• Stephens R. J., Sloan M. F., Groth D. C., Negi D. S., Lunan K. D. Cytologic response of postnatal rat lungs to O, or N02 exposure. Am. J. Pathol. 1978; 93: 183–200
   PubMed Web of Science ®Google Scholar
• Stevens J. B., Autor A. P. Proposed mechanism for neonatal rat tolerance to normo-baric hyperoxia. Fed. Proc. 1980; 39: 3138–3143
   PubMedGoogle Scholar
• Stiles J., Tyler W. S. Age-related morphometry differences in responses of rat lungs to ozone. Toxicol. Appl. Pharmacol. 1988; 92: 274–285
   PubMed Web of Science ®Google Scholar
• Thurston C. D., Ito K., Lippmann M., Hayes C. C., Bates D. V. Respiratory hospital admissions and summertime haze air pollution in Toronto, Ontario: Considerations of the role of acid aerosols. Environ. Res. 1994; 65: 271–290
   PubMed Web of Science ®Google Scholar
• Tyler W. S., Dungworth D. L., Plopper C. G., Hyde D. M., Tyler N. K. Structural evaluation of the respiratory system. Fundam. Appl. Toxicol. 1985; 5: 405–422
   PubMedGoogle Scholar
• Tyson C. A., Lunan K. D., Stephens R. J. Age-related differences in GSH-shuttle enzymes in NOr or Gyexposed rat lungs. Arch. Environ. Health 1982; 37: 167–176
   PubMed Web of Science ®Google Scholar
• Van Bree L., Marra M., Rombout P. J. A. Differences in pulmonary biochemical and inflammatory responses of rats and guinea pigs resulting from daytime or nighttime, single and repeated exposure to ozone. Toxicol. Appl. Pharmacol. 1992; 116: 209–216
   PubMed Web of Science ®Google Scholar
• Van Loveren H., Rombout P. J. A., Wagenaar S. S., Walvoort H. C., Vos J. C. Effects of ozone on the defense to a respiratory Listeria monocytogenes infection in the rat. Suppression of macrophage function and cellular immunity and aggravation of histopathology in lung and liver during infection. Toxicol. Appl. Pharmacol. 1988; 94: 374–393
   PubMed Web of Science ®Google Scholar
• Vincent R., Adamson I. Y. R. Cellular kinetics in the lungs of aging Fischer 344 rats after acute exposure to ozone. Am. J. Pathol. 1995; 146: 1008–1016
   PubMed Web of Science ®Google Scholar
• Woesnner J. F., Jr. The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Arch. Biochem. Biophys. 1961; 93: 440–447
   PubMed Web of Science ®Google Scholar
• Yam J., Frank L., Roberts R. J. Age-related development of pulmonary antioxidant enzymes in the rat. Proc. Soc. Exp. Biol. Med. 1978; 157: 293–296
   PubMed Web of Science ®Google Scholar