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Inhalation Toxicology
International Forum for Respiratory Research
Volume 8, 1996 - Issue 4
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Research Article

Uptake of Acrolein in the Upper Respiratory Tract of the F344 Rat

Pages 387-403 | Published online: 27 Sep 2008

References

  • Aharonson E. F., Menkes H., Gurtner C., Swift D. L., Proctor D. F. Effect of respiratory flow rate on removal of soluble vapors by the nose. J. Appl. Physiol. 1974; 37: 654–657
  • Badre R., Buillerm R., Abran N., Bourdin M., Dumas C. Pollution atmospherique par le fumee de tabac. Ann. Pharmaceut. Fr. 1978; 36: 443–452
  • Beauchamp R. O., Andjelkovich D. A., Klingerman D. A., Morgan K. T., Heck H. d'A. A critical review of the literature on acrolein toxicity. CRC Crit. Rev. Toxicol. 1985; 14: 309–380
  • Beck B. D., Feldman H. A., Brain J. D., Smith T. J., Hallock M., Gerson B. The pulmonary toxicity of talc and granite dust as estimated from an in vivo hamster bioassay. Toxicol. Appl. Pharmacol. 1987; 87: 222–234
  • Buckley L. A., Jiang X. Z., James R. A., Morgan K. T., Barrow C. S. Respiratory tract lesions induced by sensory irritants at the RD50 concentration. Toxicol. Appl. Pharmacol. 1984; 74: 417–429
  • Dahl A. R. Dose concepts for inhaled vapors and gases. Toxicol. Appl. Pharmacol. 1990; 103: 185–197
  • Dahl A. R., Snipes M. P., Gerde P. Sites for uptake of inhaled vapors in beagle dogs. Toxicol. Appl. Pharmacol. 1991; 109: 263–275
  • Dahlhamn T., Rosengren A. Effect of different aldehydes on tracheal mucosa. Arch. Otolaryngol. 1971; 93: 496–500
  • Dawes J. D. K., Prichard M. M. L. Studies of the vascular arrangements of the nose. J. Anat. 1953; 87: 311–322
  • Dylewska K., Sahin C., Widdicombe J. G. Asymmetric reflex responses of the nasal and tracheal vasculatures of the dog. J. Appl. Physiol. 1993; 75: 2157–2161
  • Egle J. L. Retention of inhaled formaldehyde, propionaldehyde, and acrolein in the dog. Arch. Environ. Health. 1972; 25: 119–124
  • Feingold A. Estimation of anesthetic solubility in blood. Anesth. Analgesia. 1976; 55: 593–595
  • Feron V. J., Kruysse A., Til J. P., Himmel H. R. Repeated exposure to acrolein vapour: Subacute studies in hamsters, rats and rabbits. Toxicology. 1978; 9: 47–57
  • Fiserova-Bergerova V. Cases and their solubility: A review of fundamentals. Modeling of inhalation exposure to vapors: Uptake, distribution and elimination, vol. 1, V. Fiserova-Bergerova. CRC Press, Boca Raton, FL 1983; 3–28
  • Frank N. R., Yoder R. E., Brain J. D., Yokoyama E. SO2 (35S labeled) absorption by the nose and mouth under conditions of varying concentration and flow. AMA Arch. Environ. Health. 1969; 18: 315–322
  • Gargas M. L., Gurgess R. J., Voisard D. E., Carson C. H., Andersen M. E. Partition coefficients of low-molecular-weight chemicals in various liquids and tissues. Toxicol. Appl. Pharmacol. 1989; 98: 87–99
  • Cerde P., Dahl A. R. A model for the uptake of inhaled vapors in the nose of the dog during cyclic breathing. Toxicol. Appl. Pharmacol. 1991; 109: 276–268
  • Guyton A. C. Measurement of the respiratory volumes of laboratory animals. Am. J. Physiol. 1947; 150: 70–77
  • Heck H. d'A., Casanova M., McNulty M. J., Lam C.-W. Mechanisms of nasal toxicity induced by formaldehyde and acrolein. Toxicology of the nasal passages, C. S. Barrow. Hemisphere, Washington, DC 1986; 235–247
  • Kensler C. J., Battista S. P. Components of cigarette smoke with ciliary-depressant activity. N. Engl. J. Med. 1963; 269: 1161–1166
  • Leikauf C. D., Lemin L. M., O'Donnel J. R., Doupnik C. A. Sulfidopeptide leukotrienes mediate acrolein-induced bronchial hyperresponsiveness. J. Appl. Physiol. 1989; 66: 171–178
  • Lienhard G. E., Jenks W. P. Thiol addition to the carbonyl group. Equilibria and kinetics. J. Am. Chem. Soc. 1966; 88: 3986–3998
  • Lofroth F., Burton R. M., Forehand L., Hammond S. K., Seila R. L., Zweidinger R. B., Lewtas J. Characterization of environmental tobacco smoke. Environ. Sci. Technol. 1989; 23: 610–614
  • Lowry O. H., Rosenbrough N. J., Farr A. L., Randall R. J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 1951; 193: 265–275
  • Lung M. A., Phipps R. J., Wang J. C. C., Widdicombe J. C. Control of the nasal vasculature and airflow resistance in the dog. J. Physiol. 1984; 349: 535–551
  • Miller F. J., McNeal C. A., Kirtz J. M., Gardner D. E., Coffin D. L., Menzel D. B. Nasopharyngeal removal of ozone in rabbits and guinea pigs. Toxicology. 1979; 14: 273–281
  • Morgan K. T., Cross E. A., Joyner D., Mery S. Mapping of lesions in the nose provides insight into mechanism of action of nasal toxicants. CUT Activities. 1995; 15: 1–10
  • Morris J. B. First-pass metabolism of inspired ethyl acetate in the upper respiratory tracts of the F344 rat and Syrian hamster. Toxicol. Appl. Pharmacol. 1990; 102: 331–345
  • Morris J. B. Deposition of acetone vapor in the upper respiratory tract of the B6C3F1 mouse. Toxicol. Lett. 1991; 56: 187–196
  • Morris J. B. Upper respiratory tract metabolism of inspired alcohol dehydrogenase and mixed function oxidase substrate vapors under defined airflow conditions. Inhal. Toxicol. 1993; 5: 203–221
  • Morris J. B. In vivo measurements of uptake. Inhal. Toxicol. 1994; 6: 99–111
  • Morris J. B., Blanchard K. T. Upper respiratory tract deposition of inspired acetaldehyde. Toxicol. Appl. Pharmacol. 1992; 114: 140–146
  • Morris J. B., Cavanagh D. G. Deposition of ethanol and acetone vapors in the upper respiratory tract of the rat. Fundam. Appl. Toxicol. 1986; 6: 78–88
  • Morris J. B., Cavanagh D. G. Metabolism and deposition of propanol and acetone vapors in the upper respiratory tract of the hamster. Fundam. Appl. Toxicol. 1987; 9: 34–40
  • Morris J. B., Frederick C. B. Upper respiratory tract uptake of acrylate ester and acid vapors. Inhal. Toxicol. 1995; 7: 557–574
  • Morris J. B., Smith F. A. Regional deposition and absorption of inhaled hydrogen fluoride. Toxicol. Appl. Pharmacol. 1982; 62: 81–89
  • Morris J. B., Clay R. J., Cavanagh D. G. Species differences in upper respiratory tract deposition of acetone and ethanol vapors. Fundam. Appl. Toxicol. 1986; 7: 671–680
  • Morris J. B., Clay R. J., Trela B. A., βogdanffy M. S. Deposition of dibasic esters in the upper respiratory tract of the male and female Sprague-Dawley rat. Toxicol. Appl. Pharmacol. 1991; 108: 538–546
  • Morris J. B., Hassett D. N., Blanchard K. T. A physiologically based pharmacokinetic model for nasal uptake and metabolism of nonreactive vapors. Toxicol. Appl. Pharmacol. 1993; 123: 120–129
  • Petersson G., Bacci E., McDonald D. M., Nadel J. A. Neurogenic plasam extravasation in the rat nasal mucosa is potentiated by peptidase inhibitors. J. Pharmacol. Exp. Ther. 1993; 264: 509–514
  • Sedlak J., Lindsay R. H. Estimation of total, protein bound, and nonprotein sulfhydryl groups in tissue with Elmann's reagent. Anal. Biochem. 1968; 25: 192–205
  • Sterling T. D., Dimich H., Kobayzshi D. Indoor byproduct levels of tobacco smoke: A critical review of the literature. J. Air Pollut. Control Assoc. 1982; 32: 250–259
  • Stott W. T., McKenna M. J. The comparative absorption and excretion of chemical vapors by the upper, lower, and intact respiratory tract of rats. Fundam. Appl. Toxicol. 1984; 4: 594–602
  • Strandberg L. G. SO2 Absorption in the respiratory tract. AMA Arch. Environ. Health. 1964; 9: 160–166
  • Turner C. R., Stow R. B., Talerico S. D., Christian E. P., Williams J. C. Protective role for neuropeptides in acute pulmonary response to acrolein in guinea pigs. J. Appl. Physiol. 1993; 75: 2456–2465
  • Widdicombe J. G. Comparison between the vascular beds of upper and lower airways. Eur. Respir. J. Suppl. 1990; 12
  • Zweideinger R. Volatile Organic Hydrocarbons and Aldehyde Compoisition in Raleigh, NC During the 1985 Woodsmoke Study, Integrated Air Cancer Project. U.S. EPA, Research Triangle Park, NC 1987

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