Transforming Growth Factor-α and Epidermal Growth Factor Receptor in Colonic Mucosa in Active and Inactive Inflammatory Bowel Disease

References

• Alexander R. J., Panja A., Kaplan-Liss E., Mayer L., Raicht R. F. Expression of growth factor receptorencoded mRNA by colonic epithelial cells is altered in inflammatory bowel disease. Dig. Dis. Sci 1995; 40: 485–494
   PubMed Web of Science ®Google Scholar
• Babyatsky M. W., Rossiter G., Podolsky D. K. Expression of transforming growth factor α and β in colonic mucosa in inflammatory bowel disease. Gastroenterology 1996; 110: 975–984
   PubMed Web of Science ®Google Scholar
• Bajaj-Elliott M., Breese E., Poulsom R., Fairclough P. D., MacDonald T. T. Keratinocyte growth factor in inflammatory bowel disease. Increased mRNA transcripts in ulcerative colitis compared with Crohn's disease in biopsies and isolated mucosal myofibroblasts. Am. J. Pathol 1997; 151: 1469–1476
   PubMed Web of Science ®Google Scholar
• Bird R. P. Immunohistochemical detection of transforming growth factor alpha in normal crypts, aberrant crypt foci and colonic tumors in rats. Cancer Res 1996; 37: 20–24
   Google Scholar
• Bosenberg M. W., Pandiella A., Massague J. The cytoplasmic carboxy-terminal amino acid specifies cleavage of membrane TGF alpha into soluble growth factor. Cell 1992; 71: 1157–1165
   PubMedGoogle Scholar
• Chowdhury A., Fukuda R., Fukumoto S. Growth factor mRNA expression in normal colorectal mucosa and in uninvolved mucosa from ulcerative colitis patients. J. Gastroenterol 1996; 31: 353–360
   PubMed Web of Science ®Google Scholar
• Coffey R. J., Goustin A. S., Soderquist A. M., Shipley G. D., Wolfshohl J., Carpenter G., Moses H. L. Transforming growth factor α and β expression in human colon cancer lines: Implication for an autocrine model. Cancer Res 1987; 47: 4590–4594
   PubMed Web of Science ®Google Scholar
• Derynck R., Roberts A. B., Eaton D. H., Winkler M. E., Geoddel D. V. Human transforming growth factor-alpha: precursor, gene structure, and heterologous expression. Cancer Cells 1985; 3: 79–86
   Google Scholar
• Egger B., Carey H. V., Procaccino F., Chai N. N., Sandgren E. P., Lakshmanan J., Buslon V. S., French S. W., Buchler M. W., Eysselein V. E. Reduced susceptibility of mice overexpressing transforming growth factor alpha to dextran sodium sulphate induced colitis. Gut 1998; 43: 64–70
   PubMed Web of Science ®Google Scholar
• Egger B., Procaccino F., Lakshmanan J., Reinshagen M., Hoffmann P., Patel A., Reuben W., Gnanakkan S., Liu L., Barajas L., Eysselein V. E. Mice lacking transforming growth factor α have an increased susceptibility to dextran sulfate-induced colitis. Gastroenterology 1997; 113: 825–832
   PubMed Web of Science ®Google Scholar
• Ekbom A., Helmick C., Zack M., Adami H. O. Ulcerative colitis and colorectal cancer: a population based-study. N. Engl. J. Med 1990; 323: 1228–1233
   PubMed Web of Science ®Google Scholar
• Filipe M. I., Osborn M., Linehan J., Sanidas E., Brito M. J., Jankowski J. Expression of transforming growth factor alpha, epidermal growth factor receptor and epidermal growth factor in precursor lesions to gastric carcinomas. Br. J. Cancer 1995; 71: 30–36
   PubMed Web of Science ®Google Scholar
• Gillen C. D., Walmsley R. S., Prior P., Andrews H. A., Allan R. N. Ulcerative colitis and Crohn's disease: a comparison of the colorectal cancer risk in extensive colitis. Gut 1994; 35: 1590–1592
   PubMed Web of Science ®Google Scholar
• Hoffmann P., Zeeh J. M., Lakshmanan J., Wu V. S., Procaccino F., Reinshagen M., McRoberts J. A., Eysselein V. E. Increased expression of transforming growth factor α precursors in acute experimental colitis in rats. Gut 1997; 41: 195–202
   PubMed Web of Science ®Google Scholar
• Hormi K., Lehy T. Developmental expression of transforming growth factor-a and epidermal growth factor receptor proteins in the human pancreas and the digestive tract. Cell Tissue Res 1994; 278: 439–450
   PubMedGoogle Scholar
• Hormi K., Lehy T. Transforming growth factor-or in vivo stimulates epithelial cell proliferation in digestive tissues of suckling rats. Gut 1996; 39: 532–538
   PubMedGoogle Scholar
• Ignotz R. A., Kelly B., Davis R. J., Massague J. Biologically active precursor for transforming growth factor type α, released by retrovirally transformed cells. Proc. Natl. Acad. Sci 1986; 83: 6307–6311
   PubMedGoogle Scholar
• Jankowski J., McMenemin R., Yu C., Hopwood D., Wormsley K. G. Proliferating cell nuclear antigen in oesophageal diseases; correlation with transforming growth factor alpha expression. Gut 1992; 33: 587–591
   PubMed Web of Science ®Google Scholar
• Jonsson B., Ahsgren L., Andersson L. O., Stenling R., Rutegard J. Colorectal cancer surveillance in patients with ulcerative colitis. Br. J. Surg 1994; 81: 689–691
   PubMedGoogle Scholar
• Karnes W. E., Jr., Walsh J. H., Wu S. V. Autonomous proliferation of colon carcinoma cells that coexpress transforming growth factor alpha and its receptor: variable effect of receptor-blocking antibody. Gastroenterology 1992; 102: 474–485
   PubMed Web of Science ®Google Scholar
• Konturek P. C., Brzozowski T., Konturek S. J., Ernst H., Drozdowicz D., Pajdo R., Hahn E. G. Expression of epidermal growth factor and transforming growth factor alpha during ulcer healing. Scand. J. Gastroenterol 1997; 32: 6–15
   PubMed Web of Science ®Google Scholar
• Lindberg B., Person B., Veress B., Ingelman-Sunderberg H., Granqvist S. Twenty years colonoscopic surveillance of patients with ulcerativecolitis. Scand. J. Gastroenterol 1996; 31: 1195–1204
   PubMed Web of Science ®Google Scholar
• Livingstone J. I., Filipe M. I., Wastell C. Expression of transforming growth factor alpha in experimental gastric carcinogenesis. Gut 1994; 35: 604–607
   PubMedGoogle Scholar
• Lofberg R., Broström O., Karlén P., Tribukait B., Öst A. Colonoscopic surveillance in long-standing total ulcerative colitis, a 15-year follow-up study. Gastroenterology 1990; 99: 1021–1031
   PubMed Web of Science ®Google Scholar
• Messa C., Russo F., Notarnicola M., Di Leo A. Demonstration of epidermal growth factor receptor in colorectal adenocarcinoma by enzyme immunoassay. Digestion 1994; 55: 103–107
   PubMedGoogle Scholar
• Miettinen P. J. Transforming growth factor-α and epidermal growth factor expression in human fetal gastrointestinal tract. Pediatr. Res 1993; 33: 481–486
   PubMedGoogle Scholar
• Mogi M., Matsura S., Zuzuki K., Inagaki H., Minami M., Kojima K., Harada M. Differential expression of transforming growth factor-a and epidermal growth factor during postnatal development of rat submandibular gland. Biochem. Biophys. Res. Commun 1995; 217: 271–277
   PubMedGoogle Scholar
• Playford R. J., Handy A. M., Gschmeissner S., Peiffer L. P., Wright N. J.A., McGarrity T. The epidermal growth factor receptor (EGF-r) is present on the basolateral, but not the apical surface of enterocytes in the human gastrointestinal tract. Gut 1996; 39: 262–266
   PubMedGoogle Scholar
• Rappolee D. A., Mark D., Banda M. J., Werb Z. Wound macrophages express TGF-α and other growth factors in vivo: analysis by mRNA phenotyping. Science 1988; 241: 708–712
   PubMed Web of Science ®Google Scholar
• Reimund J. M., Wittersheim C., Dumont S., Muller C. D., Kenney J. S., Baumann R., Poindron P., Duclos B. Increased production of tumor necrosis factor-a, interleukin-1, B and interleukin-6 by morphologically normal intestinal biopsies from patients with Crohn's disease. Gut 1996; 39: 684–689
   PubMed Web of Science ®Google Scholar
• Romano M., Polk W. P., Awad J. A., Arteage C. L., Nanney L. B., Wargovitch M. J. Transforming growth factor α protection against drug-induced injury in the rat gastric mucosa, in vivo. J. Clin. Invest 1992; 90: 2409–2421
   PubMed Web of Science ®Google Scholar
• Schägger H., Von Jagow G. Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal. Biochem 1987; 166: 368–379
   PubMed Web of Science ®Google Scholar
• Simpson S., Traube J., Riddell R. H. The histologic appearance of dysplasia (precarcinomatous change) in Crohn's disease of the small and large intestine. Gastroenterology 1981; 81: 492–501
   PubMed Web of Science ®Google Scholar
• Sottili M., Sternini C., Reinshagen M., Brecha N. C., Nast C. C., Walsh J. H., Eysselein V. E. Up-regulation of transforming growth factor α binding sites in experimantal rabbit colitis. Gastroenterology 1995; 109: 24–31
   PubMedGoogle Scholar
• Wang Q. S., Sabourin C. L.K., Bijur G., Robertson F. M., Stoner G. Alterations in transforming growth factor-a and epidermal growth factor receptor expression during rat esophageal tumorigenesis. Mol. Carcinogen 1996; 15: 144–153
   PubMed Web of Science ®Google Scholar
• Wang S. L., Wu- Wang C. Y., Feng J., Espina N., Garro A. J. Chronic ethanol feeding alters the structure and function of epidermal growth factor receptor in rat stomach. Alcohol 1996; 13: 461–466
   PubMedGoogle Scholar
• Wong S. T., Winchell L. F., McCune B. K., Earp H. S., Teixido J., Massaguk J., Herman B., Lee D. C. The TGF-alpha precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction. Cell 1989; 56: 495–506
   PubMed Web of Science ®Google Scholar
• Wu H. H., Kawamata H., Wang D. D., Oyasu O. Immunohistochemical localisation of transforming growth factor alpha in the major salivary glands of male and female rats. Histochem. J 1993; 25: 613–618
   PubMedGoogle Scholar
• Xian J. C., Mardell C. E., Read L. C. Differential changes in immunoreactivity of TGF-α and β1 in colonic mucosa in childhood inflammatory bowel disease. Gastroenterology 1997; 112: A1–122, (Abstract)
   Google Scholar
• Xian J. C., Mardell C. E., Read L. C. Specificity of the localization of transforming growth factor-a immunoreactivity in colon mucosa. J. Histochem. Cytochem 1999; 47: 949–957
   PubMedGoogle Scholar
• Ziober B. L., Wilson J. K.V., Hymphrey L. E., Childress-Fields K., Brattain M. G. Autocrine transforming growth factor-α is associated with progression of transformed properties in human colon cancer cell. J. Biol. Chem 1993; 268: 691–698
   PubMedGoogle Scholar