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Original Article

Characterization of IL-4 Receptor Components Expressed on Monocytes and Monocyte-derived Macrophages: Variation Associated with Differential Signaling by IL-4

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Pages 207-218 | Published online: 11 Jul 2009

References

  • Bonder C. S., Dickenshoets H. L., Finlay-Jones J. J., Donnelly R. P., Hart P. H. Involvement of the IL-2 receptor γ-chain (γc) in the control by IL-4 of human monocyte and macrophage proinflammatory mediator production. J. Immunol. 1998; 160: 4048–4056
  • Bonder C. S., Finlay-Jones J. J., Hart P. H. Interleukin-4 regulation of human monocyte and macrophage interleukin-10 and interleukin-12 production. Role of a functional interleukin-2 receptor gamma-chain. Immunology 1999; 96: 529–536
  • Chomarat P., Banchereau J. An update on IL-4 and its receptor. Eur, Cytokine Netw. 1997; 8: 333–344
  • Cunningham B. C., Utsch M., De Vos A. M., Mulkerrin M. G., Clauser K. R., Wells J. A. Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule. Science 1991; 254: 821–825
  • Daly R. J. Take your partners please—signal diversification by the erbB family of receptor tyrosine kinases. Growth Factors 1999; 16: 255–263
  • Epling-Burnette P. K., Wei S., Liu J. H., Pericle F., Ussery D., Russell S. M., Leonard W. J., Djeu J. Y. Expression of IL-2 receptor γ on human monocytes: characterization of lineage specific post-translational modifications. Eur. J. Immunol. 1995; 25: 291–294
  • Fuh G., Cunningham B. C., Fukunaga R., Nagata S., Goeddel D. V., Wells J. A. Rational design of potent antagonists to the human growth hormone receptor. Science 1992; 256: 1677–1680
  • Fujiwara H., Hanissian S. H., Tsytsykova A., Geha R. S. Homodimerization of the human interleukin 4 receptor alpha chain induces C epsilon germline transcripts in B cells in the absence of the interleukin 2 receptor gamma chain. Proc. Natl Acad. Sci. USA 1997; 94: 5866–5871
  • Galizzi L. P., Zuber C. E., Harada N., Gorman D. M., Djossou O., Kastelein R., Banchereau J., Howard M., Miyajima A. Molecular cloning of a cDNA encoding the human interleukin-4 receptor. Int. Immunol. 1990; 2: 669–675
  • Hart P. H., Vitti G. F., Burgess D. R., Whitty G. A., Piccoli D. S., Hamilton J. A. Potential antiinflammatory effects of interleukin-4: suppression of human monocyte TNFγ interleukin 1 and prostaglandin E2. Proc. Natl Acad. Sci. USA 1989; 86: 3803–3807
  • Hart P. H., Ahern M. J., Jones C. A., Jones K. A., Smith M. D., Finlay-Jones J. J. Synovial fluid macrophages and blood monocytes differ in their responses to IL-4. J. Immunol. 1993; 151: 3370–3380
  • Hart P. H., Jones C. A., Finlay-Jones J. J. Monocytes cultured in cytokine defined environments differ from freshly isolated monocytes in their responses to IL-4 and IL-10′. J. Leuk. Biol. 1995; 57: 909–918
  • Hart P. H., Bonder C. S., Balogh J., Dickensheets H. L., Vazquez N., Davies K. V.L., Finlay-Jones J. J., Donnelly R. P. Diminished responses to IL-13 by human monocytes differentiated in vitro: role of the IL-13Ralphal chain and STAT6. Eur. J. Immunol. 1999; 29: 2087–2097
  • Idzerda R. L., March C. J., Mosley B., Lyman S. D., van den Bos T., Gimpel S. D., Din W. S., Grabstein K. H., Widmer M. B., Park L. S., Cosman D., Beckman P. M. Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily. J. Exp. Med. 1990; 171: 861–873
  • Kammer W., Lischke A., Morigg B., Groner A., Ziemiecki A., Gurniak C. B., Berg L. J., Friederich K. Homodimerisation of interleukin-4 receptor a chain can induce intracellular signaling. J. Biol. Chem. 1996; 270: 23634–23631
  • Kumaki S., Ochs H. D., Kuropatwinski K. K., Konno T., Tmour M. S., Cosman D., Baumann H. A novel mutant γc chain from a patient with typical phenotype of X-linked severe combined immunodeficiency (SCD) has partial signaling function for mediating IL-2 and IL-4 receptor action. Clin Exp. Immunol. 1999; 115: 356–361
  • Lai S. Y., Molden J., Liu K. D., Puck J. M., Whit M. D., Goldsmith M. A. Interleukin4–specificc signal transduc-tion events are driven by homotypic interactions of the interleukin-4 receptor α-subunit. EMBO J. 1996; 15: 4506–4514
  • Letzelter R., Wang Y., Sebald W. The interleukin-4 site-2 epitope determining binding of the common receptor ychain. Eul. J. Biochem 1998; 257: 11–20
  • Levings M. K., Schrader J. W. IL4 inhibits the production of TNFa and IL-12 by STAT6dependent and -independent mechanisms. J. Immunol. 1999; 162: 5224–5229
  • Nelms K., Keegan A. D., Zamorano J., Ryan J. J., Paul W. E. The IL-4 receptor: signaling mechanisms and biologic functions. Annu. Rev. Immunol. 1999; 17: 701–738
  • Noguchi M., Nakamura Y., Russell S. M., Ziegler S. F., Tsang M., Cao X., Leonard W. J. Interleukin-2 receptor gamma chain: a functional component of the interleukin-7. Science 1993; 262: 1877–1880
  • Page T. H., Lali F. V., Groome N., Foxwell B. M.J. Association of the common gamma-chain with the human IL-7 receptor is modulated by T cell activation. J. Immunol. 1997; 158: 5727–5735
  • Paul W. E. Interleukin-4: a prototypic immunoregulatory lymphokine. Blood 1991; 77: 1859–1870
  • Raskin N., Jakubowski A., Sizing I.-D., Olson D. L., Kalled S. L., Hession C. A., Benjamin C. D., Baker D. P., Burkly L. C. Molecular mapping with functional antibodies localizes critical sites on the human IL receptor common gamma (γc) chain. J. Immunol. 1998; 161: 3474–3483
  • Reichel M., Nelson B. H., Greenberg P. D., Rothman P. B. The IL-4 receptor alpha-chain cytoplasmic domain is sufficient for activation of JAK-1 and STAT6 and the induction of IL-4–specific gene expression. J. Immunol. 1997; 158: 5860–5867
  • Rolling C., Treton D., Pellegrini S., Galanaud P., Richard Y. II. 4 and IL13 receptors share the γc chain and activate STAT6 STAT3 and STAT5 proteins in normal human B cells. FEBS Lett. 1996; 393: 53–56
  • Russell S. M., Keegan A. D., Harada N., Nakamura Y., Noguchi M., Leland P., Friedmann M. C., Miyajimi A., Puri R. K., Paul W. E., Leonard W. J. IL-2 receptor γ chain: a functional component of the IL-4 receptor. Science 1993; 262: 1880–1883
  • Takeshita T., Asao H., Ohtani K., Ishii N., Kumaki S., Tanaka N., Munakata H., Nakamura M., Sugmura K. Cloning of the gamma chain of the human IL-2 receptor. Science 1992; 257: 379–382
  • Xia Z., Dickens M., Raingeaud J., Davis R. J., Greenberg M. E. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995; 270: 1326–1331
  • Ziegler-Heitbrock H. W.L., Thiel E., Futterer A., Herzog V., Wirtz A., Reitmuller G. Establishment of a human cell line (Mono Mac 6) with characteristics of mature monocytes. Int. J. Cancer 1988; 41: 456–461
  • Zola H., Neoh S. H., Mantzioris B. X., Webster J., Loughnan S. Detection by immunofluorescence of surface molecules present in low copy numbers. High sensitivity staining and calibration of flow cytometer. J. Immunol. Methods 1990; 135: 247–255
  • Zurawski S. M., Chomarat P., Djossou O., Bidaud C., McKenzie A. N.J., Miossec P., Bancherau J., Zurawski G. The primary binding subunit of the human interleukin-4 receptor is also a component of the interleukin-13 receptor. J. Biol. Chem. 1995; 270: 13869–13878

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