72
Views
8
CrossRef citations to date
0
Altmetric
Articles

The influence of inhibition of the epidermal growth factor receptor on tympanic membrane wound healing in rats

, , , &
Pages 286-292 | Received 17 Nov 2009, Accepted 13 Jan 2010, Published online: 19 Feb 2010

References

  • Amoils CP, Jackler RK, Milczuk H, Kelly KE. 1992. An animal model of chronic tympanic membrane perforation. Otolaryngol Head Neck Surg. 106:47–55.
  • Bianchini D, Jayanth A, Chua YJ, Cunningham D. 2008. Epidermal growth factor receptor inhibitor-related skin toxicity: Mechanisms, treatment, and its potential role as a predictive marker. Clin Colorectal Cancer. 7:33–43.
  • Clymer MA, Schwaber MK, Davidson JM. 1996. The effects of keratinocyte growth factor on healing of tympanic membrane perforations. Laryngoscope. 106:280–285.
  • Curran D, Giralt J, Harari PM, Ang K, Cohen RB, Kies MS, Jassem J, Baselga J, Rowinsky EK, Amellal N, Comte S, Bonner JA. 2007. Quality of life in head and neck cancer patients after treatment with high-dose radiotherapy alone or in combination with cetuximab. J Clin Oncol. 25:2191–2197.
  • Dvorak DW, Abbas G, Ali T, Stevenson S, Welling B. 1995. Repair of chronic tympanic membrane perforations with long-term epidermal growth factor. Laryngoscope. 105:1300–1304.
  • Fina M, Baird A, Ryan A. 1993. Direct application of basic fibroblast growth factor improves tympanic membrane perforation healing. Laryngoscope. 103:804–809.
  • Govindan R, Behnken D, Read W, McLeod H. 2003. Wound healing is not impaired by the epidermal growth factor receptor-tyrosine kinase inhibitor gefitinib. Ann Oncol. 14:1330–1331.
  • Hapgood J, Libermann TA, Lax I, Yarden Y, Schreiber AB, Naor Z, Schlessinger J. 1983. Monoclonal antibodies against epidermal growth factor receptor induce prolactin synthesis in cultured rat pituitary cells (GH3). Proc Natl Acad Sci USA. 80:6451–6455.
  • Herbst RS, Sandler A. 2008. Bevacizumab and erlotinib: A promising new approach to the treatment of advanced NSCLC. Oncologist. 13:1166–1176.
  • Hidalgo M, Siu LL, Nemunaitis J, Rizzo J, Hammond LA, Takimoto C, Eckhardt SG, Tolcher A, Britten CD, Denis L, Ferrante K, Von Hoff DD, Silberman S, Rowinsky EK. 2001. Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies. J Clin Oncol. 19:3267–3279.
  • Huether A, Höpfner M, Baradari V, Schuppan D, Scherübl H. 2005. EGFR blockade by cetuximab alone or as combination therapy for growth control of hepatocellular cancer. Biochem Pharmacol. 70:1568–1578.
  • Ishibashi T, Shinogami M, Ishimoto SI, Yoshida K, Kaga K. 1998. Induction of KGF, basic FGF, and TGFα mRNA expression during healing of experimental TM perforations. Acta Otolaryngol. 118:701–704.
  • Jaisinghani VJ, Paparella MM, Schachern PA, Le CT. 1999. Tympanic membrane/middle ear pathologic correlates in chronic otitis media. Laryngoscope. 109:712–716.
  • Jang CH, Song CH, Pak SC. 2003. Effect of exposure to mitomycin C on cultured tympanic membrane fibroblasts. Int J Pediatr Otorhinolaryngol. 67:173–176.
  • Kaftan H, Hosemann W. 2006. Topical application of mitomycin C before versus after myringotomy: An experimental study. ORL. 68:73–76.
  • Kaftan H, Hosemann W, Beule A, Junghans D. 2004. An improved animal model for chronic perforation of the tympanic membrane. HNO. 52:714–719.
  • Kaftan H, Vogelgesang S, Lempas K, Hosemann W, Herzog M. 2007. Inhibition of epidermal growth factor receptor by erlotinib: Wound healing of experimental tympanic membrane perforations. Otol Neurotol. 28:245–249.
  • Kaftan H, Reuther L, Miehe B, Hosemann W, Herzog M. 2008. Delay of tympanic membrane wound healing in rats with topical application of a tyrosine kinase inhibitor. Wound Repair Regen. 16:364–369.
  • Kristensen S. 1992. Spontaneous healing of traumatic tympanic membrane perforations in man: A century of experience. J Laryngol Otol. 106:1037–1050.
  • Kuijpers W, Peters TA, Tonnaer ELGM. 1999. Nature of the tympanic membrane insertion into the tympanic bone of the rat. Hear Res. 128:80–88.
  • Lee AJ, Jackler RK, Kato M, Scott NM. 1994. Repair of chronic tympanic membrane perforations using epidermal growth factor: Progress toward clinical application. Am J Otol. 15:10–18.
  • Lee SM, Buchler T, Joseph T, Lai C. 2008. Bilateral eardrum perforation after long-term treatment with erlotinib. J Clin Oncol. 26:2582–2584.
  • Lehmann EL. 1998. Nonparametrics—statistical methods based on ranks. Englewood Cliffs, NJ: Prentice Hall. p 156–201.
  • Lim DJ. 1995. Structure and function of the tympanic membrane: A review. Acta Otorhinolaryngol Belg. 49:101–115.
  • Mondain M, Renard N, Ryan A. 1995. Neutralizing antibodies against basic fibroblast growth factor influence the healing of traumatic tympanic membrane perforations. ORL. 57:28–32.
  • Olsen E, Stenfors L. 1993. The behaviour of tympanic membrane perforations in tissue culture: A scanning electron microscopic study. J Laryngol Otol. 107:1106–1109.
  • Pytel D, Sliwinski T, Poplawski T, Ferriola D, Majsterek I. 2009. Tyrosine kinase blockers: New hope for successful cancer therapy. Anticancer Agents Med Chem. 9:66–76.
  • Reijnen CJH, Kuijpers W. 1971. The healing pattern of the drum membrane. Acta Otolaryngol Suppl. 287:1–74.
  • Repertinger SK, Campagnaro E, Fuhrman J, El-Abaseri T, Yuspa SH, Hansen LA. 2004. EGFR enhances early healing after cutaneous incisional wounding. J Invest Dermatol. 123:982–989.
  • Sadè J. 1993. Atelectatic tympanic membrane: Histologic study. Ann Otol Rhinol Laryngol. 102:712–716.
  • Sarkar S, Roychoudhury A, Roychaudhuri BK. 2009. Tympanoplasty in children. Eur Arch Otorhinolaryngol. 266:627–633.
  • Schmidt SH, Hellström S. 1991. Tympanic membrane structure—new views: A comparative study. ORL. 53:32–36.
  • Somers T, Goovaerts G, Schelfhout L, Peeters S, Govaerts PJ, Offeciers E. 1998. Growth factors in tympanic membrane perforations. Am J Otol. 19:428–434.
  • Spandow O, Hellström S. 1993. Animal model for persistent tympanic membrane perforations. Ann Otol Rhinol Laryngol. 102:467–472.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.