Protein kinase D mediates the synergistic effects of BMP-7 and IGF-I on osteoblastic cell differentiation

References

• Aronow MA, Gerstenfeld LC, Owen TA, Tassinari MS, Stein GS, Lian JB. 1990. Factors that promote progressive development of the osteoblast phenotype in cultured fetal rat calvarial cells. J Cell Physiol. 143:213–221.
   PubMed Web of Science ®Google Scholar
• Asahina I, Sampath TK, Nishimura I, Hauschka PV. 1993. Human osteogenic protein-1 induces both chondroblastic and osteoblastic differentiation of osteoprogenitor cells derived from newborn rat calvaria. J Cell Biol. 123:921–933.
   PubMed Web of Science ®Google Scholar
• Bikle DD, Sakata T, Leary C, Elalieh H, Ginzinger D, Rosen CJ, Beamer W, Majumdar S, Halloran BP. 2002. Insulin-like growth factor I is required for the anabolic actions of parathyroid hormone on mouse bone. J Bone Miner Res. 17:1570–1578.
   PubMed Web of Science ®Google Scholar
• Billiard J, Grewal SS, Lukaesko L, Stork PJ, Rotwein P. Hormonal control of insulin-like growth factor I gene transcription in human osteoblasts: Dual actions of cAMP-dependent protein kinase on CCAAT/enhancer-binding protein delta. J Biol Chem. 2001a; 276:31238–31246.
   PubMed Web of Science ®Google Scholar
• Billiard J, Umayahara Y, Wiren K, Centrella M, McCarthy TL, Rotwein P. Regulated nuclearcytoplasmic localization of CCAAT/enhancer-binding protein delta in osteoblasts. J Biol Chem. 2001b; 276:15354–15361.
   PubMed Web of Science ®Google Scholar
• Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 72:248–254.
   PubMed Web of Science ®Google Scholar
• Celil AB, Campbell PG. 2005. BMP-2 and insulin-like growth factor-I mediate Osterix expression in human mesenchymal stem cells via the MAPL and protein kinase D signaling pathways. J Biol Chem. 280:31353–31359.
   PubMed Web of Science ®Google Scholar
• Chen J, Lu G, Wang QJ. 2005. Protein kinase C-independent effects of protein kinase D3 in glucose transport in L6 myotubes. Mol Pharmacol. 67:152–162.
   PubMed Web of Science ®Google Scholar
• Ettinger SL, Lauener RW, Duronio V. 1996. Protein kinase C delta specifically associates with phosphatidylinositol 3-kinase following cytokine stimulation. J Biol Chem. 271:14514–14518.
   PubMed Web of Science ®Google Scholar
• Friedlander GE, Perry CR, Cole JD, Cook SD, Cierny G, Muschler GF, Zych GA, Calhoun JH, Laforte AJ, Yin S. 2001. Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions. J Bone Joint Surg Am. 83A Suppl 1: S151–S158.
   Google Scholar
• Hassel S, Schmitt S, Hartung A, Roth M, Nohe A, Petersen N, Ehrlich M, Henis YI, Sebald W, Knaus P. 2003. Initiation of Smad-dependent and Smad-independent signaling via distinct BMP-receptor complexes. J Bone Joint Surg Am. 83A Suppl 3: 44–51.
   Google Scholar
• He J, Rosen CJ, Adams DJ, Kream BE. 2006. Postnatal growth and bone mass in mice with IGF-I haploinsufficiency. Bone. 38:826–835.
   PubMed Web of Science ®Google Scholar
• Hogan BL. 1996. Bone morphogenetic proteins: Multifunctional regulators of vertebrate development. Genes Dev. 10:1580–1594.
   PubMed Web of Science ®Google Scholar
• Kim YK. 2007. TGF-β1 Induction of p21WAF1/Cip1 requires Smad-independent protein kinase C signaling pathway. Arch Pharm Res. 30:739–742.
   PubMed Web of Science ®Google Scholar
• Kingsley DM. 1994. What do BMPs do in mammals? Clues from the mouse short-ear mutation. Trends Genet. 10:16–21.
   PubMed Web of Science ®Google Scholar
• Kitten AM, Lee JC, Olson MS. 1995. Osteogenic protein-1 enhances phenotypic expression in ROS 17/2.8 cells. Am J Physiol. 269:E918–E926 Endocrinol Metab 32.
   Google Scholar
• Knutsen R, Wergedal JE, Sampath TK, Baylink DJ, Mohan S. 1993. Osteogenic protein-1 stimulates proliferation and differentiation of human bone cells in vitro. Biochem Biophys Res Commun. 194:1352–1358.
   PubMed Web of Science ®Google Scholar
• Knutsen R, Honda Y, Strong DD, Sampath TK, Baylink DJ, Mohan S. 1995. Regulation of insulin-like growth factor system components by osteogenic protein-1 in human bone cells. Endocrinology. 136:857–865.
   PubMed Web of Science ®Google Scholar
• Lemonnier J, Ghayor C, Guicheux J, Caverzasio J. 2004. Protein kinase C-independent activation of protein kinase D is involved in BMP-2-induced activation of stress mitogen-activated protein kinases JNK and p38 and osteoblastic cell differentiation. J Biol Chem. 279:259–264.
   PubMed Web of Science ®Google Scholar
• Liu P, Scharenberg AM, Cantrell DA, Matthews SA. 2007. Protein kinase D enzymes are dispensable for proliferation, survival and antigen receptor-regulated NFkappaB activity in vertebrate B-cells. FEBS Lett. 581:1377–1382.
   PubMed Web of Science ®Google Scholar
• Matthews SA, Liu P, Spitaler M, Olson EN, McKinsey TA, Cantrell DA, Scharenberg AM. 2006. Essential role for protein kinase D family kinases in the regulation of class II histone deacetylases in B lymphocytes. Mol Cell Biol. 26:1569–1577.
   PubMed Web of Science ®Google Scholar
• McCarthy TL, Centrella M, Canalis E. 1988. Further biochemical and molecular characterization of primary rat parietal bone cell cultures. J Bone Miner Res. 3:401–408.
   PubMed Web of Science ®Google Scholar
• Nakayama Y, Nakajima Y, Kato N, Takai H, Kim DS, Arai M, Mezawa M, Araki S, Sodek J, Ogata Y. 2006. Insulin-like growth factor-I increases bone sialoprotein (BSP) expression through fibroblast growth factor-2 response element and homeodomain protein-binding site in the proximal promoter of the BSP gene. J Cell Physiol. 208:326–335.
   PubMed Web of Science ®Google Scholar
• Ozkaynak E, Rueger DC, Drier EA, Cobett C, Ridge RJ, Sampath TK, Oppermann H. 1990. OP-1 cDNA encodes an osteogenic protein in the TGF-β family. EMBO J. 9:2085–2093.
   PubMed Web of Science ®Google Scholar
• Reddi AH. 2000. Bone morphogenetic proteins and skeletal development: The kidney–bone connection [In Process Citation]. Pediatr Nephrol. 14:598–601.
   PubMed Web of Science ®Google Scholar
• Sampath TK, Maliakal JC, Hauschka PV, Jones WK, Sasak H, Tucker RF, White KH, Coughlin JE, Tucker MM, Pang RH. 1992. Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro. J Biol Chem. 267:20352–20362.
   PubMed Web of Science ®Google Scholar
• Shoba LN, Lee JC. 2003. Inhibition of phosphatidylinositol 3-kinase and p70S6 kinase blocks osteogenic protein-1 induction of alkaline phosphatase activity in fetal rat calvaria cells. J Cell Biochem. 88:1247–1255.
   PubMed Web of Science ®Google Scholar
• Srinivasan N, Knutsen R, Baylink DJ, Sampath TK, Mohan S. 1995. Evidence that TGF-β, and BMP-7 increase insulin-like growth factor binding protein (IGFBP)-3 production via different protein kinase-C-dependent signal transduction pathways in human bone cells. J Bone Miner Res. 10 Suppl 1: S310.
   Google Scholar
• Stanford CM, Jacobson PA, Eanes ED, Lembke LA, Midura RJ. 1995. Rapidly forming apatitic mineral in an osteoblastic cell line (UMR 106-01 BSP). J Biol Chem. 270:9420–9428.
   PubMed Web of Science ®Google Scholar
• Storz P, Doppler H, Johannes F, Toker A. 2003. Tyrosine phosphorylation of protein kinase D in the pleckstrin homology domain leads to activation. J Biol Chem. 278:17969–17976.
   PubMedGoogle Scholar
• Storz P, Doppler H, Toker A. 2004. Protein kinase C delta selectively regulates protein kinase D-dependent activation of NF-kappaB in oxidative stress signaling. Mol Cell Biol. 24:2614–2626.
   PubMed Web of Science ®Google Scholar
• Wang QJ. 2006. PKD at the crossroads of DAG and PKC signaling. Trends Pharmacol Sci. 27:317–323.
   PubMed Web of Science ®Google Scholar
• Wang D, Yu X, Brecher P. 1998. Nitric oxide and N-acetylcysteine inhibit the activation of mitogen-activated protein kinases by angiotensin II in rat cardiac fibroblasts. J Biol Chem. 273:33027–33034.
   PubMed Web of Science ®Google Scholar
• Wozney JM, Rosen V. 1998. Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair. Clin Orthop. 346:26–37.
   PubMed Web of Science ®Google Scholar
• Yakar S, Rosen CJ, Beamer WG, Ackert-Bicknell CL, Wu Y, Liu JL, Ooi GT, Setser J, Frystyk J, Boisclair YR, LeRoith D. 2002. Circulating levels of IGF-1 directly regulate bone growth and density. J Clin Invest. 110:771–781.
   PubMed Web of Science ®Google Scholar
• Yakar S, Bouxsein ML, Canalis E, Sun H, Glatt V, Gundberg C, Cohen P, Hwang D, Boisclai Y, Leroith D, Rosen CJ. 2006. The ternary IGF complex influences postnatal bone acquisition and the skeletal response to intermittent parathyroid hormone. J Endocrinol. 189:289–299.
   PubMed Web of Science ®Google Scholar
• Yeh LC, Lee JC. 2006. Co-transfection with the osteogenic protein-1 gene and the insulin-like growth factor-I gene enhanced osteoblastic cell differentiation. Biochim Biophys Acta. 1763:57–63.
   PubMed Web of Science ®Google Scholar
• Yeh LC, Adamo ML, Kitten AM, Olson MS, Lee JC. 1996. Osteogenic protein-1-mediated IGF gene expression in primary cultures of rat osteoblastic cells. Endocrinology. 137:1921–1931.
   PubMed Web of Science ®Google Scholar
• Yeh LC, Adamo ML, Olson MS, Lee JC. 1997. Osteogenic protein-1 and insulin-like growth factor I synergistically stimulate rat osteoblastic cell differentiation and proliferation. Endocrinology. 138:4181–4190.
   PubMed Web of Science ®Google Scholar
• Yeh LC, Unda R, Lee JC. 2000. Osteogenic protein 1 differentially regulates the mRNA expression of bone morphogenetic proteins and their receptors in primary cultures of osteoblasts. J Cell Physiol. 185:87–97.
   PubMed Web of Science ®Google Scholar
• Zhang M, Xuan S, Bouxsein ML, von Stechow D, Akeno N, Faugere MC, Malluche H, Zhao G, Rosen CJ, Efstratiadis A, Clemens TL. 2002. Osteoblast-specific knockout growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization. J Biol Chem. 277:44005–44012.
   PubMed Web of Science ®Google Scholar