Platelet growth factors suppress ex vivo expansion and enhance differentiation of umbilical cord blood CD133⁺ stem cells to megakaryocyte progenitor cells

References

• Baj-Krzyworzeka M, Majka M, Pratico D, Ratajczak J, Vilaire G, Kijowski J, Reca R, Janowska-Wieczorek A, Ratajczak MZ. 2002. Platelet-derived microparticles stimulate proliferation, survival, adhesion, and chemotaxis of hematopoietic cells. Exp Hematol. 30:450–459.
   PubMed Web of Science ®Google Scholar
• Bertolini F, Lazzari L, Lauri E. 1995. Comparative study of different procedures for the collection and banking of umbilical cord blood. J Hematother Stem Cell Res. 4:29–36.
   PubMedGoogle Scholar
• Bradford M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 72:248–254.
   PubMed Web of Science ®Google Scholar
• Bruserud Ø, Foss B, Abrahamsen JF, Gjertsen BT, Ernst P. 2000. Autologous stem cell transplantation as post-remission therapy in adult acute myelogenous leukemia: Does platelet contamination of peripheral blood mobilized stem cell grafts influence the risk of leukemia relapse?. J Hematother Stem Cell Res. 9:433–443.
   PubMedGoogle Scholar
• De Wynter EA. 2003. What is the future for cord blood stem cells?. Cytotechnology. 41:133–138.
   PubMed Web of Science ®Google Scholar
• Dercksen MW, Weimar IS, Richel DJ, Breton-Gorius J, Vainchenker W, Slaper-Cortenbach CM, Pinedo HM, von dem borne AE, Gerritsen WR, van der schoot CE. 1995. The value of flow cytometric analysis of platelet glycoprotein expression of CD34+ cells measured under conditions that prevent P-selectin-mediated binding of platelets. Blood. 86:3771–3782.
   PubMed Web of Science ®Google Scholar
• Doucet C, Ernou I, Zhang Y, Llense JR, Begot L, Holy X, Lataillade JJ. 2005. Platelet lysates promote mesenchymal stem cell expansion: A safety substitute for animal serum in cell-based therapy applications. JCP. 9999:1–9.
   Google Scholar
• Fargeas CA, Fonseca AV, Huttner WB, Corbeil WB. 2006. Prominin-1 (CD133): From progenitor cells to human diseases. Future Lipidol. 1:213–225.
   Web of Science ®Google Scholar
• Fargeas CA, Huttner WB, Corbeil WB. 2007. Nomenclature of prominin-1 (AC133) splice variants- an updates. Tissue Antigens. 69:602–606.
   PubMed Web of Science ®Google Scholar
• Feng R, Shimazaki C, Inaba T, Takahashi R, Hirai H, Kikuta T, Sumikuma T, Yamagata M, Ashihara E, Fujita N. 1998. CD34/CD41a+ cells best predict platelet recovery after autologous peripheral blood stem cell transplantation. Bone Marrow Transplant. 21:1217–1222.
   PubMed Web of Science ®Google Scholar
• Foss B, Abrahamsen JF, Bruserud Ø. 2001. Peripheral blood stem cell grafts contain high levels of platelet-secreted mediators. Transfusion. 41:1431–1437.
   PubMed Web of Science ®Google Scholar
• Foss B, Bruserud Ø, Hervig T. 2008. Platelet-released supernatants enhance hematopoietic stem cell proliferation in vitro. Platelets. 19 2: 155–159.
   PubMed Web of Science ®Google Scholar
• Gluckman E. 2001. Hematopietic-stem cell transplants using umbilical-cord blood. N Engl J Med. 344:1860–1861.
   PubMed Web of Science ®Google Scholar
• Gluckman E, Rocha V, Boyer-Chammard A, Locatelli F, Arcese W, Pasquini R, Ortega J, Souillet G, Ferreira E, Laporte JP, Fernandez M, Chastang C. 1997. Outcome of cord blood transplantation from related and unrelated donors. N Engl J Med. 337:373–381.
   PubMed Web of Science ®Google Scholar
• Goodarzi A, Kheirandish M, Pourfathollah A. 2007. Characterization of Megakaryocyte Progenitor Cells Differentiated from Umbilical Cord Blood CD133+ and CD133– Cells. Yakhteh Med J. 9:190–195.
   Google Scholar
• Graziani F, Ivanovski S, Cei S, Ducci F, Tonetti M, Gabriele M. 2006. The in vitro effect of different PRP concentrations on osteoblasts and fibroblasts. Clin Oral Imp Res. 17:212–219.
   PubMed Web of Science ®Google Scholar
• Gutensohn K, Bartsch N, Kuehnl P. Flow cytometric analysis of platelet membrane antigens during and after continuous-flow plateletpheresis. Transfusion. 1997a; 37:809–815.
   PubMed Web of Science ®Google Scholar
• Gutensohn K, Maerz M, Kuehnl P. Alteration of platelet-associated membrane glycoproteins during extracorporeal apheresis of peripheral blood progenitor cells. J Hematother. 1997b; 6:315–321.
   PubMedGoogle Scholar
• Han Z C, Sensebe L, Abgrall J F, Brieve J. 1990. Platelet factor 4 inhibits human megakaryopoiesis in vitro. Blood. 75:1234–1239.
   PubMed Web of Science ®Google Scholar
• Harris D. 2008. Collection, processing, and banking of umbilical cord blood stem cells for clinical use in transplantation and regenerative medicine. Lab Med. 39:173–178.
   Google Scholar
• Kaps C, Loch A, Haisch A. 2002. Human platelet supernatant promotes proliferation but not differentiation of articular chondrocytes. Med Biol Eng Comput. 40:485–490.
   PubMed Web of Science ®Google Scholar
• Kaushansky K, Broudy VC, Lin N, Jorgensen MJ, McCarty J, Fox N, Zucker-Franklin D, Lofton-Day C. 1995. Thrombopoietin, the Mpl ligand, is essential for full megakaryocyte development. Proc Natl Acad Sci USA. 92:3234–3238.
   PubMed Web of Science ®Google Scholar
• Keler JR, Mcniece AK, Sill KT. 1990. Transforming growth factor β directly regulates primitive murine hematopoietic cell proliferation. Blood. 75:596–602.
   PubMed Web of Science ®Google Scholar
• Kilian O, Flesch I, Wenisch S, Taborski B, Jork A, Schnettler R, Jonuleit T. 2004. Effects of Platelet Growth Factors on Human Mesenchymal Stem Cells and Human Endothelial Cells In vitro. Eur J Med Res. 9:337–344.
   PubMed Web of Science ®Google Scholar
• Kleinman S, Chan P, Robillard P. 2003. Risks Associated With Transfusion of Cellular Blood Components in Canada. Transfus Med Rev. 17:120–162.
   PubMed Web of Science ®Google Scholar
• Kogler G, Nurnberger W, Fischer J, Niehues T, Somville T, Gobel U. 1999. Simultaneous cord blood transplatelet Lysate annotation of ex vivo expanded together with non-ex vivo expanded cells for high risk leukemia. Bone Marrow Transplant. 24:397–403.
   PubMed Web of Science ®Google Scholar
• Kuter D, Gminski D, Rosenberg R. 1992. Transforming growth factor β inhibits megakaryocyte growth and endomitosis. Blood. 79:619–625.
   PubMed Web of Science ®Google Scholar
• Lam AC, Li K, Zhang XB, Li CK, Fok TF, Chang AM, James AE, Tsang KS, Yuen PM. 2001. Preclinical ex vivo expansion of cord blood hematopoietic stem and progenitor cells: During of culture; the media, serum supplements, and growth factor used; and engraftment in NOD/SCID mice. Transfusion. 41:1567–1576.
   PubMed Web of Science ®Google Scholar
• Liu J, Li K, Yuen PM, Fok TF, Yau FW, Yang M, Li CK. 1999. Ex vivo expansion of enriched CD34+ cells from neonatal blood in the presence of thrombopoietin, a comparison with cord blood and bone marrow. Bone Marrow Transplant. 24:247–252.
   PubMed Web of Science ®Google Scholar
• Lucarelli E, Beccheroni A, Donati D. 2003. Platelet derived growth factors enhance proliferation of human stromal stem cells. Biomaterials. 24:3095–3310.
   PubMed Web of Science ®Google Scholar
• Martieau I, Lacoste E, Gagnon G. 2004. Effects of calcium and thrombin on growth factor release from platelet concentrates: Kinetics and regulation of endothelial cell proliferation. Biomaterials. 25:4489–4502.
   PubMed Web of Science ®Google Scholar
• Marx RE. 2004. Platelet-rich plasma: Evidence to support its use. Am Assoc Oral Maxillofac Surg. 62:489–496.
   PubMed Web of Science ®Google Scholar
• Miltenyi S. 1997. CD34+ Selection: The Basic Component for Graft Engineering. Oncologist. 2:410–413.
   PubMedGoogle Scholar
• Ogino Y, Ayukawa Y, Kukita T. 2006. Transforming Growth factor-β1, and Insulin-like Growth Factor-1 in Platelet Rich Plasma to the Proliferation of Osteoblast-like Cells. Oral Surg Oral Med. 101:724–729.
   Google Scholar
• Pasino M, Lanza T, Marotta F, Scarso L, De Biasio P, Amato S, Corcione A, Pistoia V, Mori PG. 2000. Flow cytometric and functional characterization of AC133+ cells from umbilical cord blood. Br J Hematol. 108:793–800.
   PubMed Web of Science ®Google Scholar
• Pecora AL, Stiff P, Jennis A, Goldberg S, Rosenbluth R, Price P, Goltry KL, Douville J, Armstrong RD, Smith AK, Preti RA. 2000. Prompt and durable engraftment in two older adult patients with high risk chronic myelogenous leukemia (CML) using ex vivo expanded and unmanipulated unrelated umbilical cord blood. Bone Marrow Transplant. 25:797–799.
   PubMed Web of Science ®Google Scholar
• Piacibello P, Sanavio F, Severino A, Dane A, Gmaitoni L, Fagioli F, Perissinotto E, Cavalloni G, Kollet O, Lapidot T, Aglietta M. 1999. Engraftment in nonobese diabetic severe combined immunodeficiency mice of human CD34 (+) cord blood cells after ex vivo expansion: Evidence for the application and self-renewal repopulating stem cells. Blood. 93:3736–3749.
   PubMed Web of Science ®Google Scholar
• Pranke PJ, Hendrikx Debnath G, Alespeiti G, Rubinstein P, Nardi N, Visser J. 2005. Immunophenotype of hematopoietic stem cells from placental/umbilical cord blood after culture. Braz J Med Biol Res. 38:1775–1789.
   PubMed Web of Science ®Google Scholar
• Reddy NP, Vemuri MC, Pallu R. 2007. Isolation of stem cells from human umbilical cord blood. Methods Mol Biol. 407:149–163.
   PubMedGoogle Scholar
• Rocha V, Cornish J, Sievers EL, Filipovich A, Locatelli F, Peters C, Remberger M, Michel G, Arcese W, Dallorso S, Tiedemann K, Busca A, Chan KW, Kato S, Ortega J, Vowels M, Zander A, Souillet G, OaKll A, Woolfrey A, Pay AL, Green A, Garnier F, Ionescu I, Wernet P, Sirchia G, Rubinstein R, Chevret S, Gluckman G. 2001. Comparison of outcomes of unrelated bone marrow and umbilical cord blood transplants in children with acute leukemia. Blood. 97:2962–2971.
   PubMed Web of Science ®Google Scholar
• Rubinstein P. 2006. Why cord blood?. Human Immunology. 67:398–404.
   PubMed Web of Science ®Google Scholar
• Rubinstein P, Carrier C, Scaradavou A, Kurtsberg J, Adamson J, Migliaccio AR, Berkowitz RL, Cabbad M, Dobrila NL, Taylor PE, Rosenfield RE, Stevens CE. 1998. Outcomes among 562 recipients of placental-blood transplants from unrelated donors. N Engl J Med. 339:1565–1577.
   PubMed Web of Science ®Google Scholar
• Saigo K, Kumagai S, Sugimoto T, Matsui T, Ryo R. 2001. RANTES and p-Selectin in peripheral blood stem. Ther Apher Dial. 5:517–518.
   Web of Science ®Google Scholar
• Schallmoser K, Bartmann C, Rohde E, Reainisch A, Kashofer K, Stadelmeyer E, Drexler C, Lanzer G, Linkesch W, Strunk D. 2007. Human platelet lysate can replace fetal bovine serum for clinical-scale expansion of functional mesenchymal stromal cells. Transfusion. 47:1436–1446.
   PubMed Web of Science ®Google Scholar
• Schmid I, Uittenbogaart CH, Krall WJ, Braun J, Giorgi JV. 1992. Dead cell discrimination with 7-amino-actinomycin D in combination with dual color immunofluorescence in single laser flow cytometry. Cytometry. 13:204–208.
   PubMedGoogle Scholar
• Skoric D, Balint B, Petakov M. 2007. Collection strategies and cryopreservation of umbilical cord blood. Transfus Med. 17:107–113.
   PubMed Web of Science ®Google Scholar
• Stroncek DF, Clay ME, Smith J, Herr G, Ilstrup SJ, Kunkel LA, McCullough J. 1997. Composition of peripheral blood progenitor cell components collected from a healthy donors. Transfusion. 37:411–417.
   PubMed Web of Science ®Google Scholar
• Stroncek DF, Clay ME, Jaszcz W, Lennon S, Smith J, McCullough J. 1999. Collection of two peripheral blood stem cell concentrates from healthy donors. Transfus Med. 9:37–50.
   PubMed Web of Science ®Google Scholar
• Su RJ, Li K, Yang M, Zhang XB, Tsang KS, Fok TF, Li CK, Yuen PMP. 2001. Platelet – derived growth factor enhances ex vivo expansion of megakaryocytic progenitors from human cord blood. Bome Marrow Transplantat. 27:1075–1080.
   PubMed Web of Science ®Google Scholar
• Sundell B, Cheung EN, Terry D, Sheridan W. 2000. Effects of megakaryocyte growth and development factor on platelet production, platelet life span, and platelet function in healthy human volunteers. Blood. 95:8.
   Web of Science ®Google Scholar
• Tan KK, Tang KZ, Huang S. 2007. Devices for umbilical cord blood collection. Recent Pat Eng. 1:89–94.
   Google Scholar
• Tao H, Gaudry L, Rice A, Chong B. 1999. Cord blood is better than bone marrow for generation megakaryocytic progenitor cells. Exp Hematol. 27:293–301.
   PubMed Web of Science ®Google Scholar
• Vladareanu AM, Mihailescu D, Tudosa R, Zvanca M, Vladareanu R. 2007. Cord blood stem cells. Where do we stand?. J Clin Med. 2:142–152.
   Google Scholar
• Voss R, Scarlat T, Matzdorff A, Tillmanns H. 1996. Flow cytometric detection of platelet activation in patients undergoing diagnostic and interventional coronary angiography. Platelets. 7:237–241.
   PubMed Web of Science ®Google Scholar
• Yang Mo, Chesterman CN, Chong BH. 1995. Recombinant PDGF enhances megakaryocytopoiesis in vitro. Br J Hematol. 91:285–289.
   PubMed Web of Science ®Google Scholar
• Yoo ES, Ryu KH, Park HY, Seong CM, Chung WS, Kim SC, Choi YM, Hahn MJ, Woo SY, Seoh JY. 1999. Myeloid differentiation of human cord blood CD34+ cells during ex vivo expansion using thrombopoietin, flt3-ligand and/or granulocyte-colony stimulating factor. Br J Hematol. 105:1034–1040.
   PubMed Web of Science ®Google Scholar
• Zimmermann R, Arnold D, Strasser E, Ringwald J, Schlegel A, Wiltfang J, Eckstein R. 2003. Sample preparation technique and white cell content influence the detectable levels of growth factors in platelet concentrates. Vox Sang. 85:283–289.
   PubMed Web of Science ®Google Scholar
• Zimmermann R, Jakubietz R, Jakubietz M, Strasser E, Schlegel A, Wiltfang J, Eckstein R. 2001. Different preparation methods to obtain platelet components as a source of growth factors for local application. Transfusion. 41:1217–1224.
   Web of Science ®Google Scholar
• Zingsem J, Glaser A, Weisbach V. 1998. Evaluation of a platelet apheresis technique for the preparation of leukocyte-reduced platelet concentrates. Vox Sang. 74:189–192.
   PubMed Web of Science ®Google Scholar