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Original Article

Accelerated Healing of Ulcer Wounds in the Rabbit Ear by Recombinant Human Transforming Growth Factor-β1

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Pages 273-282 | Received 14 Aug 1989, Accepted 11 Sep 1989, Published online: 11 Jul 2009

References

  • Brown G. L., Curtsinger L., Brightwell J. R., Ackerman D. M., Tobin G.R., Polk H. C, Nascimento P., Valenzuela C. C., Schultz G. S. Enhancement of epidermal regeneration by biosynthetic epidermal growth factor. J. Exp. Med. 1986; 163: 1319–1324
  • Buckley A., Hill K.E., Davidson J. M. Collagen metabolism. Methods Enzumol. 1988; 163: 674–694
  • Centreila M., McCarthy T. L., Canaiis E. Transforming growth factor β is a bifunctional regulator of replication and collagen synthesis in osteobtast-enriched cell cultures from fetal rat bones. J. Biol. Chem. 1987; 26′2: 2869–2874
  • Chen T.U., Hauschka P. V., Cabrales S., Feldman D. The effects of1,25-dihydroxyvitamin D3 and dexamethasone in rat osteoblast-like primary cell cultures: Receptor occupancy and functional expression patterns for three different bio-responses. Endocrinology 1986; 118: 250–259
  • Davidson J. M., Klagsbrun M., Hill K. E., Buckley A., Sullivan R., Brewer P. S., Woodward S.C. Accelerated wound repair, cell proliferation, and collagen accumulation produced by a cartilage-derived growth factor. J. Cell. Biol. 1985; 100: 1219–1227
  • Davidson J. M., Buckley A., Woodward, Nichols S. C., McGee W.K. G. S., Demetriou A. Mechanisms of accelerated wound repair using epidermal growth factor and basic fibroblast growth factor. Growth Factors and Other Aspects of Wound Healing: Biological and Clinical Implications, R. Alan Liss, New York 1988; 63–75
  • Derynck R., Jarrett J. A., Chen E. Y., Eaton D. H., Bell J. R., Assoian R. K., Roberts A. B., Spom M. B., Goeddel D.V. Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells. Nature 1985; 316: 701–705
  • Eisinger S., Sadan M., Silver I. A., Flick R. B. Growth regulation of skin cells by epidermal cell-derived factors: Implications for wound healing. Proc. Natl. Acad. Sci. USA 1988; 85: 1937–1941
  • Franklin J. D., Lynch J. B. Effects of topical application of epidermal growth factor on wound healing: Experimental study on rabbit ears. Plast. Reconstr. Surg. 1979; 64: 766–770
  • Gospodarowicz D., Neufeld G., Schweigerer L. Fibroblast growth factor. Mol. Cell. Endocrinol. 1986; 46: 187–204
  • Hannan R. L., Kourembanas S., Flanders K.C., Rogelj S. J., Roberts A. B., Faller D. V., Klagsbrun M. Endothelial cells synthesize basic fibroblast growth factor and transforming growth factor beta. Growth Factors 1988; 1: 7–17
  • Hebda P. A. Stimulatory effects of transforming growth factor-β and epidermal cell outgrowth from porcine skin explant cultures. J. Invest. Dermatol. 1988; 91: 440–445
  • Hockel M., Jung W., Vaupel P., Rabes H., Khaledpour C., Wissler J. H. Purified monocyte-derived angiogenic substance (angiotropin) induces controlled angiogenesis associated with regulated tissue proliferation in rabbit skin. J. Clin. Invest. 1988; 82: 1075–1090
  • Kehrl J. H., Wakefield L. M., Roberts A. B., Jakowiew S., Alvarez-Mon M., Derynck R., Spom M. B., Fauci A. S. The production of TGF-β by human T lymphocytes and its potential role in the regulation of T cell growth. J. Exp. Med. 1986; 163: 1037–1050
  • Lawrence W. T., Spom M. B., Gorschboth C., Norton J. A., Grotendorst G. R. The reversal of an adriamycin induced healing impairment with chemo-attractants and growth factors. Ann. Surg. 1986; 203: 142–147
  • Leibovich S. J., Wiseman D. M. Macrophages, wound repair and angiogenesis. Growth Factors and Other Aspects of Wound Healing: Biological and Clinical Implications, R. Alan Liss, New York 1988; 131–145
  • Lynch S. E., Nixon J. C., Colvin R. B., Anotoniades H. N. Role of platelet-derived growth factor in wound healing: Synergistic effects with other growth factors. Proc. Natl. Acad. Sri. USA 1987; 84: 7696–7700
  • Moses H. L., Tucker R. F., Leof E. B., Halper J., Shipley G. D. Type-beta transforming growth factor is a growth stimulator and a growth inhibitor. Cancer Cells, Cold Spring Harbor Laboratories. Cold Spring, NY 1985; 65–71
  • Mustoe T. A., Pierce G. F., Morishima C., Deuel R. F. Growth factor induced acceleration of tissue repair through direct and inductive activities in a rabbit dermal ulcer model. J. Cell. Biol 1989, (submitted)
  • Mustoe T. A., Pierce G. F., Thomason A., Gramates P., Spom M. B., Deuel T. F. Accelerated healing of incisional wounds in rats induced by transforming growth factor-. Science 1987; 237: 1333–1336
  • Nemeth G. G., Bolander M. E., Martin G. R. Growth factors and their role in wound and fracture healing. Growth Factors and Other Aspects of Wound Healing: Biological and Clinical Implications, R. Alan Liss, New York 1988; 1–17
  • Peacock E. E. Wound Repair. Saunders, Philadelphia 1984; 102–140
  • Peterkofsky B. The effect of ascorbic acid in collagen polypeptide synthesis and proline hydroxylation during the growth of cultured fibroblasts. Arch. Biochem. Biophys. 1972; 152: 318–328
  • Peterkofsky B., Diegelmann R. F. Use of a mixture of proteinase-free collagenases for the specific assay of radioactive collagen in the presence of other proteins. Biochemistry 1971; 10: 988–993
  • Pierce G. F., Mustoe T. A., LingleHch J., Masakowski V. R., Gramates P., Deuel T. F. Transforming growth factor β reverses the glucocorticoid-induced wound-healing deficit in rats: Possible regulation in macrophages by platelet-derived growth factor. Proc. Natl. Acad. Sci. USA 1989; 86: 2229–2233
  • Postlethwaite A. E., Keski-Oja )., Moses H., Kang A. Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor β. J. Exp. Med. 1987; 165: 251–256
  • Roberts A. B., Spom M. B., Assoian R. K., Smith J. M., Roche N. S., Wakefield L. M., Heine U.I., Liotta L. A., Falanga V., Kehrl J. H., Fauci A. S. Transforming growth factor type β: Rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc. Natl. Acad. Sci. USA 1986; 83: 4167–4171
  • Shipley G. D., Pittelkow M. R., Wille J. J., Scott R. E., Moses H. L. Reversible inhibition of normal human prokeratinocyte proliferation by type beta transforming growth factor–growth inhibitor in serum–free medium. Cancer Res. 1986; 46: 2068–2071
  • Sporn M. B., Roberts A. B., Shull J. H., Smith J. M., Ward J. M. Polypeptide transforming growth factors isolated from bovine sources and used for wound healing in vivo. Sriract 1983; 219: 1329–1331
  • Sporn M. B., Roberts A. B., Wakefieid L. M., DeCrom-Bugghe B. Some recent advances in the chemistry and biology of transforming growth factor-β. J. Cell Biol. 1987; 105: 1039–1045
  • Wahl S. M., Hunt D. A., Wakefield L. M., McCartney F. N., Wahl L. M., Roberts A. B., Spom M. B. Transforming growth factor type β induces monocyte chemotaxis and growth factor production. Proc. Natl. Acad. Sci. USA 1987; 84: 5788–5792

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