10
Views
12
CrossRef citations to date
0
Altmetric
Original Article

Functional Expression of the Human Receptor for Colony-Stimulating Factor 1 (CSF-1) in Hamster Fibroblasts: CSF-1 Stimulates Na+/H+ Exchange and DNA-Synthesis in the Absence of Phosphoinositide Breakdown

, , , &
Pages 289-300 | Published online: 03 Aug 2009

References

  • Ashmun R. A., Look A. T., Roberts W. M., Roussel M. F., Seremetis S. T., Ohtsuka M., Sherr C. J. Monoclonal antibodies to the human CSF-1 receptor (c-fms protooncogene product) detect epitopes on normal mononuclear phagocytes and on human myeloid leukemic blast cells. Blood 1989; 73: 827–838
  • Chambard J. C., Paris S., L'Allemain G., Pouysségur J. Two growth factor signalling pathways distinguished by pertussis toxin. Nature 1987; 326: 800–803
  • Coussens L., Van Beveren C., Smith D., Chen E., Mitchell R. L., Isacke C. M., Ullrich A. Structural alteration of viral homologue of receptor protooncogene fms at carboxvl terminus. Nature 1986; 320: 277–286
  • Downing J. R., Rettenmier C. W., Sherr C. J. Ligand-induced tyrosine kinase activity of the colony stimulating factor-1 receptor in a murine macrophage cell line. Mol. Cell. Biol. 1988; 8: 1795–1799
  • Hampe A., Gobet M., Sherr C. J., Galibert F. Nucleotide sequence of the feline retroviral oncogene v-fms shows unexpected homology with oncogenes encoding tyrosine-specific protein kinases. Proc. Natl. Acad. Sci. USA 1984; 81: 85–89
  • Hanks S. K., Quinn A. M., Hunter T. The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science 1988; 241: 42–52
  • Heard J. M., Roussel M. F., Rettenmier C. W., Sherr C. J. Synthesis, posttranslational processing, and autocrine transforming activity of a carboxylterminal truncated form of colony stimulating factor-1. Oncogene Res. 1987; 1: 423–440
  • Imamura K., Kufe D. Colony-stimulating factor 1-induced Na influx into human monocytes involves activation of a pertussis toxin-sensitive GTP-binding protein. J. Biol. Chem. 1988; 263: 14093–14098
  • L'Allemain G., Pouysségur J. EGF and insulin action in fibroblasts. Evidence that phosphoinositide hydrolysis is not an essential mitogenic signalling pathway. FEBS Lett. 1986; 197: 344–348
  • L'Allemain G., Paris S., Pouysségur J. Growth factor action and intracellular pH regulation in fibroblasts. Evidence for a major role of the Na-/H- antiport. J. Biol. Chem. 1984; 259: 5809–5815
  • L'Allemain G., Seuwen K., Velu T., Pouysségur J. Signal transduction in hamster fibroblasts overexpressing the human EGF receptor. Growth Factors 1989; 1: 311–321
  • Magnaldo I., Pouysségur J., Paris S. Thrombin exerts a dual effect on stimulated adenylate cyclase in hamster fibroblasts, an inhibition via a GTP-binding protein and a potentiation via activation of protein kianase C. Biochem. J. 1988; 253: 711–719
  • Magnaldo I., Pouysségur J., Paris S. Fibroblast growth factor potentiates receptor- and non-receptor-mediated stimulation of adenylate cyclase in hamster fibroblasts. Cell. Signalling 1989, (in press)
  • Moolenaar W. H. Effects of growth factors on intracellular pH regulation. Annu. Rev. Physiol. 1986; 48: 363–376
  • Paris S., Pouysségur J. Pertussis toxin inhibits thrombin-induced activation of phosphoinositide hydrolysis and Na-/H- exchange in hamster fibroblasts. EMBO J. 1986; 5: 55–60
  • Paris S., Chambard J. C., Pouysségur J. Tyrosine kinase-activating growth factors potentiate thrombin- and A1F4-induced phosphoinositide breakdown in hamster fibroblasts: evidence for positive cross-talk between the two mitogenic signaling pathways. J. Biol. Chem. 1988; 263: 12893–12900
  • Pouysségur J. The growth factor activatable Na-H- exchange system: a generic approach. Trends Biochem. Sci. 1988; 10: 453–455
  • Pouysségur J., Franchi A., Kohno M., L'Allemain G., Paris S. Na-/H- exchange and growth control in fibroblasts: A genetic approach. Curr. Topics Membr. Transport. 1986; 26: 201–220
  • Pouysségur J., Chambard J. C., L'Allemain G., Magnaldo I., Seuwen K. Transmembrare signalling pathways initiating cell growth in fibroblasts. Phil. Trans. R. Soc. London ‘Biol.’ 1988; 320: 427–436
  • Rettenmier C. W., Roussel M. F., Ashmun R. A., Ralph P., Price K., Sherr C. J. Synthesis of membrane-bound colony-stimulating factor-1 (CSF-1) and downmodulation of CSF-1 receptors in NIH 3T3 cells transformed by cotransfection of the human CSF-1 and c-fms (CSF-1 receptor) genes. Mol. Cell. Biol. 1987; 7: 2378–2387
  • Roussel M. F., Rettenmier C. W., Look A. T., Sherr C. J. Cell surface expression of v-fms-coded glycoproteins is required for transformation. Mol. Cell. Biol. 1984; 4: 1999–2009
  • Roussel M. F., Dull T. J., Rettenmier K. W., Ralph P., Ullrich A., Sherr C. J. Transforming potential of the fms protooncogene (CSF-1 receptor). Nature 1987; 325: 549–552
  • Roussel M. F., Downing J. R., Ashmun R. A., Rettenmier C. W., Sherr C. J. Colony-stimulating factor 1-mediated regulation of a chimeric c-fms/v-fms receptor containing the v-fms-encoded tyrosine kinase domain. Proc. Natl. Acad. Sci. USA 1988a; 85: 5903–5907
  • Roussel M. F., Downing J. R., Rettenmier C. W., Sherr C. J. A point mutation, in the extracellular domain of the human CSF-1 receptor (c-fms proto-oncogene product) activates its transforming potential. Cell 1988b; 55: 979–988
  • Rozengurt E. Early signals in the mitogenic response. Science 1986; 234: 161–166
  • Sardet C., Franchi A., Pouysségur J. Molecular cloning of the human growth factor-activatable Na-/H- anti-porter. Cold Spring Harbor Symp. Quant. Biol. 1988; 53: 1011–1118
  • Sawyer S. T., Cohen S. Enhancement of Ca2- uptake and phosphoinositide turnover by EGF in A431 cells. Biochemistry 1981; 20: 6280–6286
  • Sengupta A., Liu W. K., Yeung Y. G., Yeung D. C. Y., Frackelton A. R., Stanley E. R. Identification and subcellular localization of proteins that are rapidly phosphorylated in tyrosine in response to colony-stimulating factor 1. Proc. Natl. Acad. Sci. USA 1988; 85: 8062–8066
  • Seuwen K., Magnaldo I., Pouysségur J. Serotonin stimulates DNA synthesis in fibroblasts acting through 5-HT18 receptors coupled to a G1-protein. Nature 1988a; 335: 254–256
  • Seuwen K., Lagarde A., Pouysségur J. Deregulation of hamster fibroblast proliferation by mutated res oncogenes is not mediated by constitutive activation of phosphoinositide-specific phospholipase C. EMBO J. 1988b; 7: 161–168
  • Sherr C. J., Stanley E. R. Colony stimulating factor-1. Peptide Growth Factors and Their Receptors, M. B. Sporn, A. B. Roberts. Springer-Verlag, Heidelberg 1989, (in press)
  • Sherr C. J., Rettenmier C. W., Sacca R., Roussel M. F., Look A. T., Stanley E. R. The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1. Cell 1985; 41: 665–676
  • Sherr C. J., Ashmun R. A., Downing J. R., Ohtsuka M., Quan S. G., Golde D. W., Roussel M. F. Inhibition of colony stimulating factor-1 activity by monoclonal antibodies to the human CSF-1 receptor. Blood 1989; 73: 1786–1793
  • Stanley E. R., Guilbert L. J., Tushinski R. J., Bartelmez S. H. CSF-1—a mononuclear phagocyte lineage-specific hemopoietic growth factor. J. Cell. Biochem. 1983; 21: 151–159
  • Ui M. Islet-activating protein, pertussis toxin: a probe for functions of the inhibitory guanine nucleotide regulatory component of adenylate cyclase. Trends Pharmacol. Sci. 1984; 5: 277–279
  • Vairo G., Hamilton J. A. Activation and proliferation signals in murine macrophages: Stimulation of Na-, K--ATPase activity by hematopoietic growth factors and other agents. J. Cell. Physiol. 1988; 134: 13–24
  • Vara F., Rozengurt E. Stimulation of Na-/H- antiport activity by epidermal growth factor and insulin occurs without activation of protein kinase C. Biochem. Biophys. Res. Commun. 1985a; 130: 646–653
  • Vara F., Schneider J. A., Rozengurt E. Ionic responses rapidly elicited by activation or protein kinase C in quiescent Swiss 3T3 cells. Proc. Natl. Acad. Sci. USA 1985b; 82: 2384–32388
  • Wahl I. M., Sweatt J. D., Carpenter G. Epidermal growth factor (EGF) stimulates inositol trisphosphate formation in cells which overexpress the EGF receptor. Biochem. Biophys. Res. Commun. 1987; 342: 688–695
  • Whetton A. D., Monk P. N., Consalvey S. D., Downes C. P. The haemopoietic growth factors interleukin 3 and colony stimulating factor-1 stimulated proliferation but do not induce inositol lipid breakdown in murine bone-marrow-derived macrophages. EMBO J. 1986; 5: 3281–3286
  • Woolford J., McAuliffe A., Rohrschneider L. R. Activation of the feline c-fms proto-oncogene: Multiple alterations are required to generate a fully transformed pheno-type. Cell 1988; 55: 965–977

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.