4
Views
22
CrossRef citations to date
0
Altmetric
Original Article

Subcellular Distribution of Basic Fibroblast Growth Factor in Human Hepatoma Cells

, &
Pages 189-196 | Received 24 Aug 1990, Accepted 24 Sep 1990, Published online: 11 Jul 2009

References

  • Abraham J. A., Mergia A., Whang J-L., Tumulo A., Friedman J., Gospodarowicz D., Fiddes J. C. Nucleotide sequence of a bovine clone encoding the angiogenic protein, basic fibroblast growth factor. Science 1986; 233: 545–548
  • Acland P., Dixon M., Peters G., Dickson C. Subcellular fate of the Int-2 oncogene is determined by choice of initiation codon. Nature 1990; 343: 662–665
  • Azizkhan J. C., Klagsbrun M. Chondrocytes contain a growth factor that is localized in the nucleus and is associated with chromatin. Proc. Natl. Acad. Sri. USA 1980; 77: 2762–2766
  • Baird A., Ling N. Fibroblast growth factors are present in the extracellular matrix produced by endothelial cells in vitro implications for a role of heparinase-like enzymes in the neovascular response. Biochem. Biophys. Res. Commun. 1987; 142: 428–435
  • Baldin V., Roman A.-M., Bosc-Bierne I., Amalric F., Bouche G. Translocation of bFGF to the nucleus is G, phase cell specific in bovine aortic endothelial cells. EMBO J. 1990; 9: 1511–1517
  • Bashkin P., Doctrow S., Klagsbrun M., Svahn C. M., Folkman J., Vlodavsky I. Basic fibroblast growth factor binds to subendothelial extracellular matrix and is released by heparitinase and heparin-like molecules. Biochemistry 1989; 28: 1737–1743
  • Bouche G., Gas N., Prats H., Baldin V., Tauber J. P., Tessie J., Almaric F. Basic fibroblast growth factor enters the nucleolus and stimulates the transcription of ribosomal genes in ABAE cells undergoing G0-G1 transition. Proc. Natl. Acad. Sci. USA 1987; 84: 6770–6774
  • Brigstock D. R., Klagsbrun M., Sasse J., Farber P. A., Iberg N. Species-specific high molecular weight forms of basic fibroblast growth factor. Growth Factors 1990, in press
  • Esch F., Baird A., Ling N., Ueno N., Hill F., Denoroy L., Klepper R., Gospodarowicz D., Bohlen P., Guillemin R. Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF. Proc. Natl. Acad. Sci. USA 1985; 62: 6507–6511
  • Evans W. H. Preparation and characterization of mammalian plasma membranes. Laboratory Techniques in Biochemistry and Molecular Biology, T. S. Work, E. Work. Elsevier/North Holland Biomedical Press, Amsterdam 1979; Vol. 7: 1–266
  • Feige J-J., Baird A. Basic fibroblast growth factor is a substrate for protein phosphorylation and is phosphorylated by capillary endothelial cells in culture. Proc. Natl. Acad. Sci. USA 1989; 86: 3174–3178
  • Florkiewicz R., Sommer A. Human basic fibroblast growth factor encodes four polypeptides: three initiate from non-AUG codons. Proc. Natl Acad. Sci. USA 1989; 86: 3978–3981
  • Folkman J., Klagsbrun M. Angiogenic Factors. Science 1987; 235: 442–447
  • Folkman J., Klagsbrun M., Sasse J., Wadzinski M., Ingber D., Vlodavsky I. A heparin-binding angiogenic protein–basic fibroblast growth factor–is stored within basement membrane. Am. J. Path. 1988; 130: 393–400
  • Garrard W. T., Hancock R. Preparation of chromatin from animal tissues and cultured cells. Methods in Cell Biology, G. Stein, J. Stein, L. J. Kleinsmith. Academic Press, New York 1978; Vol. 17: 27–48
  • Gonzalez A-M., Buscaglia M., Ong M., Baird A. Distribution of basic fibroblast growth factor in the 18-day rat fetus: localization in the basement membrane of diverse tissues. J. Cell Biol. 1990; 110: 753–765
  • Gospodarowicz D., Neufeld G., Schweigerer L. Molecular and biological characterization of fibroblast growth factor, an angiogenic factor which also controls the proliferation of mesoderm and neuroectoderm derived cells. Cell Differentiation 1986; 19: 1–17
  • Iberg N., Rogelj S., Fanning P., Klagsbrun M. Purification of 18 kDa and 22 kDa forms of basic fibroblast growth factor from rat cells transformed by the ras oncogene. J. Biol. Chem. 1989; 264: 19951–19955
  • Kardami E., Fandrich R. R. Basic fibroblast growth factor in atria and ventricles of the vertebrate heart. J. Cell. Biol. 1989; 109: 1865–1875
  • Klagsbrun M. The fibroblast growth factor family: structural and biological properties. Prog. Growth Factor Res. 1989; 1: 207–235
  • Klagsbrun M., Shing Y. Heparin-affinity of anionic and cationic capillary endothelial cell growth factors: Analysis of hypothalamus-derived growth factors and fibroblast growth factors. Proc. Natl. Acad. Sci. USA 1985; 82: 805–809
  • Lee P. L., Johnson D. E., Cousens L. S., Fried V. A., Williams L. T. Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor. Science 1989; 245: 57–60
  • Lobb R., Sasse J., Sullivan R., Shing Y., D'Amore P., Jacobs J., Klagsbrun M. Purification and characterization of heparin-binding endothelial cell growth factors. J. Biol. Chem. 1986; 261: 1924–1928
  • Logan A. Intracrine regulation at the nucleus–a further mechanism of growth factor activity?. J. Endocrin. 1990; 125: 339–343
  • Mansukhani A., Moscatelli D., Talarico D., Levytska V., Basilico C. A murine fibroblast growth factor (FGF) receptor expressed in CHO cells is activated by basic FGF and Kaposi FGF. Proc. Natl. Acad. Sci. USA 1990; 87: 4378–4382
  • Masayuki I., Fedarko N. S., Conrad H. E. Transport of heparan sulfate into the nuclei of hepatocytes. J. Biol. Chem. 1986; 261: 13575–13580
  • Mascarelli F., Raulais D., Courtois Y. Fibroblast growth factor phosphorylation and receptors in rod outer segments. EMBO J. 1989; 8: 2265–2273
  • Moenner N., Chevallier B., Badet J., Barritault D. Evidence and characterization of the receptor to eye-derived growth factor I, the retinal form of basic fibroblast growth factor, on bovine epithelial cells. Proc. Natl. Acad. Sci. USA 1986; 83: 5024–5028
  • Moscatelli D. High and low affinity binding sites for basic fibroblast growth factor on cultured cells: Absence of a role for low affinity binding in the stimulation of plasminogen activator production by bovine capillary endothelial cells. J. Cell. Physiol. 1987; 131: 123–130
  • Muramatsu M., Hayashi T., Onishi M., Sakai K., Kashiyama T. Rapid isolation of nucleoli from detergent purified nuclei of various tumor and tissue cells. Exp. Cell Res. 1974; 88: 345–351
  • Neufeld G., Gospodarowicz D. The identification and partial characterization of the fibroblast growth factor receptor of baby hamster kidney cells. J. Biol. Chem. 1985; 260: 13860–13868
  • Olwin B. B., Hauschka S. D. Identification of the fibroblast growth factor receptor of Swiss 3T3 cells and mouse skeletal muscle myoblasts. Biochemistry 1986; 25: 3487–3492
  • Prats H., Kaghad M., Prats A. C., Klagsbrun M., Lelias J. M., Liauzan P., Chalon P., Tauber J. P., Amalric F., Smith J. A., Caput D. High molecular mass forms of basic fibroblast growth factor are initiated by alternative CTG codons. Proc. Natl. Acad. Sci. USA 1989; 86: 1836–1840
  • Renko M., Quarto N., Morimoto T., Rifkin D. B. Nuclear and cytoplasmic localization of different basic fibroblast growth factor species. J. Cell. Physiol. 1990; 144: 108–114
  • Vlodavsky I., Fridman R., Sullivan R., Sasse J., Klagsbrun M. Aortic endothelial cells synthesize basic fibroblast growth factor which remains cell associated and platelet-derived growth factor-like protein which is secreted. J. Cell. Physiol. 1987; 131: 402–408

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.