78
Views
25
CrossRef citations to date
0
Altmetric
Review Article

Designing Liposomal Anticancer Drug Formulations for Specific Therapeutic Applications

, , &
Pages 99-115 | Published online: 28 Sep 2008

References

  • Mayer L. D., Tai L. C.L., Ko D. S.C., Masin D., Ginsberg R. S., Cullis P. R., Bally M. B. Influence of Vesicle Size, Lipid Composition and Drug-to-Lipid Ratio on the Biological Activity of Liposomal Doxorubicin. Cancer Res. 1989; 49: 5922–5930
  • Hwang K. J. Liposome pharmacokinetics. Liposomes: from Biophysics to Therapeutics, M. J. Ostro. Marcel Dekker, New York 1987; 109–156
  • Allen T. M. Long-circulating (sterically stabilized) liposomes for targeted drug delivery. Trends in Pharm. ScL 1994; 15: 215–220
  • Woodle M. C., Lasic D. D. Sterically stabilized liposomes. Biochim. Biophys. Acta 1992; 1113: 171–199
  • Ahmad I., Longenecker M., Samuel J., Allen T. M. Antibody-targeted delivery of doxorubicin entrapped in sterically stabilized liposomes can eradicate lung cancer in mice. Cancer Res. 1993; 53: 1484–1488
  • Kirpotin D., Park J. W., Hong K., Zalipsky S., Li W. L., Carter P., Benz C. C., Paphadjopoulos D. Sterically stabilized anti-HER2 immunoliposomes: design and targeting to human breast cancer cells in vitro. Biochemistry 1997; 36: 66–75
  • Yuan F., Dellian M., Fukumura D., Leunig M., Berk D. A., Torchilin V. P., Jain RK. Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size. Cancer Res. 1995; 55: 3752–3756
  • Wu N. Z., Rudoll T. L., Needham D., Whorton A. R., Dewhirst M. W. Increased microvascular permeability contributes to preferential accumulation of stealth liposomes in tumor tissue. Cancer Res. 1993; 53: 3765–3770
  • Webb M. S., Harasym T. O., Masin D., Bally M. B., Mayer L. D. Sphingomyelin-cholesterol liposomes significantly enhance the pharmacokinetic and therapeutic properties of vincristine in murine and human tumor models. Br. J. Cancer 1995; 72: 896–904
  • Parr M. J., Masin D., Cullis P. R., Bally M. B. Accumulation of liposomal lipid and encapsulated doxorubicin in murine Lewis Lung carcinoma: the lack of beneficial effects by coating liposomes with poly(ethylene glycol). J. Pharmacol. Exp. Therapeut. 1997; 280: 1319–1324
  • Swenson C. E., Freitag J., Janoff A. S. The Liposome Company: Lipid-based pharmaceuticals in clinical development. Medical Applications of Liposomes, D. Lasic, D. Papahadjopoulos. Elsevier, New York, NY 1998; 689–702
  • Martin F. Clinical pharmacology and antitumor efficacy of DOXIL (pegylated liposomal doxorubicin): Sequus Pharmaceuticals, Inc. Medical Applications of Liposomes, D. Lasic, D. Papahadjopoulos. Elsevier, New York, NY 1998; 635–688
  • Colbern G. T., Dykes D. J., Engbers C., Musterer R., Hiller A., Pegg E., Saville R., Weng S., Luzzio M., Uster P., Amantea M., Working P. K. Encapsulation of the topoisomerase I inhibitor GL147211C in pegylated (STEALTH) liposomes: pharmacokinetics and antitumor activity in HT29 colon tumor xenografts. Clin. Cancer Res. 1998; 4: 3077–3082
  • Adlakha-Hutcheon G., Bally M. B., Shew C. R., Madden T. D. Controlled Destabi-iization of a Liposomal Drug Delivery System Enhances Mitoxantrone Antitumor Acitivity. Nature Biotech. 1999; 17: 775–779
  • Newman M. S., Colbern G. T., Working P. K., Engbers C., Amantea M. A. Comparative pharmacokinetics, tissue distribution, and therapeutic effectiveness of cis-platin encapsulated in long-circulating, pegylated liposomes (SPI-077) in tumor-bearing mice. Cancer Chemother. Pharmacol. 1999; 43: 1–7
  • Sharma A., Straubinger R. M., Ojima I., Bernacki R. J. Antitumor efficacy of taxane liposomes on a human ovarian tumor xenograft in nude athymic mice. J. of Pharm. Sci. 1995; 84: 1400–404
  • Park J. W., Hong K., Kirpotin D. B., Meyer O., Papahadjopoulos D., Benz C. Anti-HER2 immunoliposomes for targeted therapy of human tumors. Cancer Lett. 1997; 118: 153–160
  • Lopes de Menezes Pilarski L. M., Allen T. M. In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma. Cancer Res. 1998; 58: 3320–3330
  • Herman E. H., Rahman A., Ferrans V. J., Vicks J. A., Schein P. S. Prevention of chronic doxorubicin cardiotoxicity in beagles by liposomal encapsulation. Cancer Res. 1983; 43: 5427–5432
  • Van Hossel Q. G.C.M., Steerenberg P. A., Crommelin D. J.A., van Dijk A., van Oost W., Klein S., Douze J. M.C., de Wildt D. J., Hillen F. C. Reduced Cardiotoxicity and nephrotoxicity with preservation of antitumor activity of doxorubicin entrapped in stable liposomes in the LOU/M Wsl Rat. Cancer Res. 1984; 44: 3698–3705
  • Rahman A., White G., Moore N., Schein P. S. Pharmacological, toxicological and therapeutic evaluation in mice of doxorubicin entrapped in liposomes. Cancer Res. 1985; 45: 796–803
  • Hong R. L., Huang C. J., Tseng Y. L., Pang V. F., Chen S. T., Liu J. J., Chang F. H. Direct comparison of liposomal doxorubicin with or without polyethylene glycol coating in C-26 tumor-bearing mice: is surface coating with polyethylene glycol beneficial?. Clin. Cancer Res. 1999; 5: 3645–3652
  • Lum B., Gosland M. MDR expression in normal tissues: Pharmacologic implications for the clinical use of P-glycoprotein inhibitors. Hematol. Oncol. Clin. North Am. 1995; 9: 319
  • Colombo T., Paz O. G., D'lncalci M. Distribution and activity of doxorubicin combined with SDZ PSC 833 in mice with P388 and P388/DOX leukemia. Br. J. Cancer 1996; 73: 866–873
  • Krishna R., Mayer L. D. Liposomal doxorubicin circumvents PSC 833-free drug interactions, resulting in effective therapy of multidrug resistant solid tumors. Cancer Res. 1997; 57: 5246
  • Krishna R., St Louis M., Mayer L. D. Increased intracellular drug accumulation and complete chemosensitization achieved in multidrug-resistant solid tumors by co-administring Valspodar (PSC 833) with sterically stabilized liposomal doxorubicin. Int. J. Cancer 2000; 85: 131–141
  • Krishna R., McIntosh N., Riggs K. W., Mayer L. D. Doxorubicin encapsulated in sterically stabilized liposomes exhibits renal and biliary clearance properties that are independent of Valspodar (PSC 833) under conditions that significantly inhibit nonencapsulated drug excretion. Clin. Cancer Res. 1999; 5: 2939–2947
  • Mayer L. D., Bally M. B., Loughrey H., Masin D., Cullis P. R. Liposomal Vincristine Preparations Which Exhibit Decreased Toxicity and Increased Anti-tumour Activity Against Murine L1210 and P388 Tumours. Cancer Research 1990; 50: 575–579
  • Mayer L. D., Masin D., Nayar R., Boman N. L., Bally M. B. Pharmacology of Liposomal Vincristine in Mice Bearing L1210 Ascitic and B16/BL6 Solid Tumors. British J. Cancer 1995; 71: 482–488
  • Boman N. L., Mayer L. D., Cullis P. R. Optimization of Vincristine Retention in Liposomes In Vitro and In Vivo. Biochim. Biophys. Acta 1993; 1152: 253–260
  • Bowman N. L., Masin D., Mayer L. D., Cullis P. R., Bally M. B. Liposomal Vincristine Which Exhibits Increased Drug Retention and Increased Circulation Longevity Cures Mice Bearing P388 Tumors. Cancer Res. 1994; 54: 2830–2833

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.