Development and modeling of arsenic-trioxide–loaded thermosensitive liposomes for anticancer drug delivery

References

• Allen, T. M., Cullis, P. R. (2004). Drug delivery systems: entering the mainstream. Science 303:1818–1822.
   PubMed Web of Science ®Google Scholar
• Andrasko, J., Forsen, S. (1974). NMR study of rapid water diffusion across lipid bilayers in dipalmitoyl lecithin vesicles. Biochem Biophys Res Commun 60:813–819.
   PubMed Web of Science ®Google Scholar
• Anyarambhatla, G. R., Needham, D. (1999). Enhancement of phase transition permeability of DPPC liposomes by incoproration of MPPC: a new temperature-sensitive liposome for use with mild hyperthermia. J Liposome Res 9:499–514.
   Web of Science ®Google Scholar
• Au, W.-Y., Kumana, C. R., Lam, C.-W., Cheng, V. C. C., Shek, A. W., Chan, E. Y. T. et al. (2007). Solid tumors subsequent to arsenic trioxide treatment for acute promyelomic leukemia. Leuk Res 31:105–108.
   PubMed Web of Science ®Google Scholar
• Berendsen, H. J. C., Postma, J. P. M., van Gunsteren, W. F., DiNola, A., Haak, J. R. (1984). Molecular dynamics with coupling to an external bath. J Chem Phys 81:3684–3690.
   Web of Science ®Google Scholar
• Blume, G., Cevc, G. (1990). Liposomes for sustained drug release in vivo. Biochim Biophys Acta 1029:91–97.
   PubMed Web of Science ®Google Scholar
• Carruthers, A., Melchior, D. L. (1983). Study of the relationship between bilayer water permeability and bilayer physical state. Biochemistry 22:5797–5807.
   Web of Science ®Google Scholar
• Chen, H., MacDonald, R., Li, S., Krett, N., Rosen, S., O’Halloran, T. V. (2006). Lipid encapsulation of arsenic trioxide attenuates cytotoxicity and allows for controlled anticancer drug release. J Am Chem Soc 128:13348–13349.
   PubMed Web of Science ®Google Scholar
• Cheung, W. M. W., Chu, P. W. K., Kwong, Y. L. (2007). Effects of arsenic trioxide on the cellular proliferation, apoptosis, and differentiation of human neuroblastoma cells. Cancer Lett 246:122–128.
   PubMedGoogle Scholar
• Cui, X., Toshifumi, W., Shirai, Y., Naoyuki, Y., Hatakeyama, N., Hirano, S. (2006). Arsenic trioxide inhibits DNA methyltransferase and restores methylation-silenced genes in human liver cancer cells. Hum Pathol 37:298–311.
   PubMed Web of Science ®Google Scholar
• Cullis, P. R., Fenske, D. B., Hope, M. J. (1996). Physical properties and functional roles of lipids in membranes. In: Vance, D. E., Vance, J. E. (Eds.), Biochemistry of lipids, lipoproteins, and membranes, 3rd ed. Amsterdam, The Netherlands: Elsevier.
   Google Scholar
• DiSalvo, E. A., Simon, S. A. (1995). Permeability of lipid bilayers near the phase transition. Boca Raton, Florida, USA: CRC Press.
   Google Scholar
• Griffin, R. J., Lee, S. H., Rood, K. L., Stewart, M. J., Lyons, J. C., Lew, Y. S. et al. (2000). Use of arsenic trioxide as an antivascular and thermosensitizing agent in solid tumors. Neoplasia 2:555–560.
   PubMed Web of Science ®Google Scholar
• Griffin, R. J., Monzen, H., Williams, B. W., Park, H., Lee, S. H., Song, C. W. (2003). Arsenic trioxide induces selective tumour vascular damage via oxidative stress and increases thermosensitivity of tumours. Int J Hypertherm 19:575–589.
   PubMed Web of Science ®Google Scholar
• Huilgol, N. G. (2006). A phase I study to study arsenic trioxide with radiation and hyperthermia in advanced head and neck cancer. Int J Hypertherm 22:391–397.
   PubMed Web of Science ®Google Scholar
• Humphrey, W., Dalke, A., Schulten, K. (1996). VMD: visual molecular dynamics. J Mol Graphics 14:33–38, 27–28.
   PubMed Web of Science ®Google Scholar
• Karatekin, E., Sandre, O., Guitouni, H., Borghi, N., Puech, P. H., Brochard-Wyart, F. (2003). Cascades of transient pores in giant vesicles: line tension and transport. Biophys J 84:1734–1749.
   PubMed Web of Science ®Google Scholar
• Kong, G., Dewhirst, M. W. (1999). Hyperthermia and liposomes. Int J Hypertherm 15:345–370.
   PubMed Web of Science ®Google Scholar
• Kuo, A. L., Wade, C. G. (1979). Lipid lateral diffusion by pulsed nuclear magnetic resonance. Biochemistry 18:2300–2308.
   PubMed Web of Science ®Google Scholar
• Lee, B.-S., Mabry, S. A., Jonas, A., Jonas, J. (1995). High-pressure proton NMR study of lateral self-diffusion of phosphatidylcholines in sonicated unilamellar vesicles Chem Phys Lipids 78:103–117.
   PubMedGoogle Scholar
• Lindahl, E., Hess, B., Spoel, D. V. D. (2001). A package for molecular simulation and trajectory analysis. J Mol Mod 7:306–317.
   Web of Science ®Google Scholar
• Lippe, C., Gallucci, E., Storelli, C. (1971). Permeabilities of ethylene glycol and glycerol through lipid bilayer membranes and some epithelia. Arch Int Physiol Biochim 79:315–318.
   PubMed Web of Science ®Google Scholar
• Marrink, S. J., De Vries, A. H., Mark, A. E. (2004). Coarse grained model for semiquantitative lipid simulations. J Phys Chem B 108:750–760.
   Web of Science ®Google Scholar
• Marrink, S. J., Risselada, H. J., Yefimov, S., Tieleman, D. P., De Vries, A. H. (2007). The MARTINI force field: coarse-grained model for biomolecular simulations. J Phys Chem B 111:7812–7824.
   PubMed Web of Science ®Google Scholar
• Marrink, S. J., Risselada, J., Mark, A. E. (2005). Simulation of gel phase formation and melting in lipid bilayers using a coarse-grained model. Chem Phys Lipids 135:223–244.
   PubMed Web of Science ®Google Scholar
• Mills, J., Needham, D. (2005). Lysolipid incorporation in dipalmitoylphosphatidylcholine bilayer membranes enhances the ion permeability and drug release rates at the membrane phase transition. Biochim Biophys Acta 1716:77–96.
   PubMed Web of Science ®Google Scholar
• Needham, D., Dewherst, M. W., Wright, A., Ponce, A. M. (2006). Targeted bioavailability of drugs by triggered release from liposomes. Future Lipidol 1:25–34.
   Google Scholar
• Needham, D. M., Mills, J.K. (2004). The materials engineering of temperature-sensitive liposomes. Meth Enzymol 387:82–113.
   PubMedGoogle Scholar
• Papahadjopoulos, D., Jacobsen, K., Nir, S., Isac, T. (1973). Phase transitions in phospholipid vesicles. Fluorescence polarization and permeability measurements concerning the effects of temperature and cholesterol. Biochim Biophys Acta 311:330–348.
   PubMed Web of Science ®Google Scholar
• Ponce, A. M., Viglianti, B. L., Yu, D., Yarmolenko, P. S., Michelich, C. R., Woo, J. et al. (2007). Magnetic resonance imaging of temperature-sensitive liposome release: drug dose painting and antitumor effects. J Natl Cancer I 99:53–63.
   PubMed Web of Science ®Google Scholar
• Sandstrom, M. C., Ickenstein, L. M., Mayer, L. D., Edwards, K. (2005). Effects of lipid segregation and lysolipid dissociation on drug release from thermosensitive liposomes. J Contr Rel 107:131–142.
   PubMed Web of Science ®Google Scholar
• Sheats, J. R., McConnell, H. M. (1978). A photochemical technique for measuring lateral diffusion of spin-labeled phospholipids in membranes. Proc Natl Acad Sci U S A 75:4661–4663.
   PubMedGoogle Scholar
• Shen, Z.-X., Chen, G. Q., Ni, J. H., Li, X. S., Xiong, S. M., Qiu, Q. Y. et al. (1997). Use of arsenic trioxide (As2O3 ) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients. Blood 89:3354–3360.
   PubMed Web of Science ®Google Scholar
• Tieleman, D. P., Leontiadou, H., Mark, A. E., Marrink, S.-J. (2003). Simulation of pore formation in lipid bilayers by mechanical stress and electric fields. J Am Chem Soc 125:6382–6383.
   PubMed Web of Science ®Google Scholar
• Winter, N. D., Schatz, G. C. (2010). Coarse-grained molecular dynamics study of permeability enhancement in DPPC bilayers by incorporation of lysolipid. J Phys Chem B 114:5053–5060.
   PubMed Web of Science ®Google Scholar