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Research Article

HPLC assay and pharmacokinetics and tissue distribution study of glycyrrhetinic acid liposomes modified with galactosylated lipid

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Pages 120-127 | Received 24 Jul 2011, Accepted 24 Sep 2011, Published online: 07 Feb 2012

References

  • Chien C. F., Wu Y. T., Tsaia T. H. (2011). Biological analysis of herbal medicines used for the treatment of liver diseases. Biomed Chromatogr 25:21–38.
  • Guo, B. H., Cheng, Y., Lin, L. P., Lin, D. H., Wu, W. (2011). Preparation and characterization of galactose-modified liposomes by a nonaqueous enzymatic reaction. J Liposome Res 21:255–260.
  • Hirano, K., Hunt, C. A. (1985). Lymphatic transport of liposome-encapsulated agents: effects of liposome size following intraperitoneal administration. J Pharm Sci 74:915–921.
  • Immordino, M. L., Brusa, P., Arpicco, S., Stella, B., Dosio, F., Cattel, L. (2003). Preparation, characterization, cytotoxicity, and pharmacokinetics of liposomes containing docetaxel. J Control Release 91:417–429.
  • Jia, L., Garza, M., Wong, H., Reimer, D., Redelmeier, T., Camden, J. B., et al. (2002). Pharmacokinetic comparison of intravenous carbendazim and remote loaded carbendazim liposomes in nude mice. J Pharm Biomed Anal 28:65–72.
  • Jeong, H. G., Kim, J. Y. (2002a). Induction of inducible nitric oxide synthase expression by 18beta-glycyrrhetinic acid in macrophages. FEBS Lett 513:208–212.
  • Jeong, H. G., You, H. J., Park, S. J., Moon, A. R., Chung, Y. C., Kang, S. K., et al. (2002b). Hepatoprotective effects of 18beta-glycyrrhetinic acid on carbon tetrachloride-induced liver injury: inhibition of cytochrome P450 2E1 expression. Pharmacol Res 46:221–227
  • Kotwani, R. N., Gokhale, P. C., Bodhe, P. V., Kirodian, B. G., Kshirsagar, N. A., Pandya, S. K. (2002). A comparative study of plasma concentrations of liposomal amphotericin B (L-AMP-LRC-1) in adults, children, and neonates. Int J Pharm 238:11–15.
  • Kim, D. H., Hong, S. W., Kim, B. T., Bae, E. A., Park, H. Y., Han, M. J. (2000). Biotransformation of glycyrrhizin by human intestinal bacteria and its relation to biological activities. Arch Pharm Res 23:172–177.
  • Li, J., Yu, H., Li, S., Wang, G. J. (2010). Enhanced distribution and extended elimination of glycyrrhetinic acid in mice liver by mPEG-PLA modified (mPEGylated) liposome. J Pharm Biomed Anal 51:1147–1153.
  • Lee, C. S., Kim, Y. J., Lee, M. S., Han, E. S., Lee, S. J. (2008). 18beta-Glycyrrhetinic acid induces apoptotic cell death in SiHa cells and exhibits a synergistic effect against antibiotic anti-cancer drug toxicity. Life Sci Sep 3:481–489.
  • Liang, J. Y., Wang, S.M., Chung, T.H., Yang, S. H., Wu, J. C. (2008). Effects of 18-glycyrrhetinic acid on serine 368 phosphorylation of connexin43 in rat neonatal cardiomyocytes. Cell Biol Int 32:1371–1379.
  • Lin, G., Nnane, I. P., Cheng, T. Y. (1999). The effects of pretreatment with glycyrrhizin and glycyrrhetinic acid on the retrorsine-induced hepatotoxicity in rats. Toxicon 37:1259–1270.
  • Lu, Y., Li, J., Wang, G. J. (2008). In vitro and in vivo evaluation of mPEG-PLA modified liposomes loaded glycyrrhetinic acid. Int J Pharm 356:274–281.
  • Nagayas, A., Uchiyama, K., Kiwada, H. (1999). The size of liposomes: a factor which affects their targeting efficiency to tumors and therapeutic activity of liposomal antitumor drugs. Adv Drug Deliv Rev 40:75–87.
  • Puglia, C., Rizza, L., Drechsler, M., Bonina, F. (2010). Nanoemulsions as vehicles for topical administration of glycyrrhetic acid: characterization and in vitro and in vivo evaluation. Drug Deliv 17:123–129.
  • Sáez, C. G., Velásquez, L., Montoya, M., Eugenín, E., Alvarez, M. G. (2003). Increased gap junctional intercellular communication is directly related to the anti-tumor effect of all-trans-retinoic acid plus tamoxifen in a human mammary cancer cell line. J Cell Biochem 89:450–461.
  • Sada, E., Katoh, S., Terashima, M., Kawahara, H., Katoh, M. (1990). Effects of surface charges and cholesterol content on amino acid permeabilities of small unilamllar vesicles. J Pharm Sci 79:232–235.
  • Serra, A., Uehlinger, D. E., Ferrari, P., Dick, B., Frey, B. M., Frey, F. J.,et al. (2002). Glycyrrhetinic acid decreases plasma potassium concentrations in patients with anuria. J Am Soc Nephrol 13:191–196.
  • Shimizu, K., Maitani, Y., Takayama, K., Nagai, T. (1996). Evaluation of dipalmitoylphosphatidylcholine liposomes containing a soybean-derived sterylglucoside mixture for liver targeting. J Drug Target 4:245–253.
  • Shah, V. P., Midha, K. K., Findlay, J. W., Hill, H. M., Hulse, J. D., McGilveray, J., et al. (2000). Bioanalytical method validation—a revisit with a decade of progress. Pharm Res 17:1551–1557.
  • Tian, Q., Wang, X., Wang, W., Zhang, C., Liu, Y., Yuan, Z. (2010a). Insight into glycyrrhetinic acid: the role of the hydroxyl group on liver targeting. Int J Pharm 400:153–157.
  • Tian, Q., Zhang, C. N., Wang, X. H., Wang, W., Huang, W., Cha, R. T., et al. (2010b). Glycyrrhetinic acid-modified chitosan/poly(ethylene glycol) nanoparticles for liver-targeted delivery. Biomaterials 31:4748–4756.
  • Takeuchi, H., Kojima, H., Toyoda, T., Yamamoto, H., Hino, T., Kawashima, Y. (1999). Prolonged circulation time of doxorubicin-loaded liposomes coated with a modified polyvinyl alcohol after intravenous injection in rats. Eur J Pharm Biopharm 48:123–129.
  • Wang, S.M., Xu, H., Xu, J.H., Zhang, Y., Liu, Y.C., Deng, Y.H., et al. (2010). Sustained liver targeting and improved antiproliferative effect of doxorubicin liposomes modified with galactosylated lipid and PEG-Lipid. AAPS PharmSciTech 11:870–877.
  • Xiao, Y., Xu, J., Mao, C., Jin, M., Wu, Q., Zou, J., et al. (2010). 18Beta-glycyrrhetinic acid ameliorates acute Propionibacterium acnes-induced liver injury through inhibition of macrophage inflammatory protein-1alpha. J Biol Chem 285:1128–1137.

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