Production of limit size nanoliposomal systems with potential utility as ultra-small drug delivery agents

References

• Allen TM, Hansen C, Martin F, et al. (1991). Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo. Biochim Biophys Acta 1066:29–36
   PubMed Web of Science ®Google Scholar
• Bally MB, Nayar R, Masin D, et al. (1990). Liposomes with entrapped doxorubicin exhibit extended blood residence times. Biochim Biophys Acta 1023:133–9
   PubMed Web of Science ®Google Scholar
• Batzri S, Korn ED. Single bilayer liposomes prepared without sonication. (1973). Biochim Biophys Acta 298:1015–19
   PubMed Web of Science ®Google Scholar
• Belliveau NM, Huft J, Lin PJ, et al. (2012). Microfluidic synthesis of highly potent limit-size lipid nanoparticles for in vivo delivery of siRNA. Mol Ther Nucleic Acids 1:e37
   PubMedGoogle Scholar
• Cabral H, Matsumoto Y, Mizuno K, et al. (2011). Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size. Nat Nanotechnol 6:815–23
   PubMed Web of Science ®Google Scholar
• Chen S, Tam YYC, Lin PJC, et al. (2014). Development of lipid nanoparticle formulations of siRNA for hepatocyte gene silencing following subcutaneous administration. J Conrol Release 196:106–12
   PubMed Web of Science ®Google Scholar
• Charrois GJ, Allen TM. (2004). Drug release rate influences the pharmacokinetics, biodistribution, therapeutic activity, and toxicity of pegylated liposomal doxorubicin formulations in murine breast cancer. Biochim Biophys Acta 1663:167–77
   PubMed Web of Science ®Google Scholar
• Chauhan VP, Jain RK. (2013). Strategies for advancing cancer nanomedicine. Nat Mater 12:958–62
   PubMed Web of Science ®Google Scholar
• Chauhan VP, Stylianopoulos T, Boucher Y, Jain RK. (2011). Delivery of molecular and nanoscale medicine to tumors: transport barriers and strategies. Annu Rev Chem Biomol Eng 2:281–98
   PubMed Web of Science ®Google Scholar
• De Kruijff B, Cullis PR, Radda GK. (1975). Differential scanning calorimetry and 31P NMR studies on sonicated and unsonicated phosphaditylcholine liposomes. Biochim Biophys Acta 406:6–20
   PubMed Web of Science ®Google Scholar
• Dreher MR, Liu W, Michelich CR, et al. (2006). Tumour vascular permeability, accumulation, and penetration of macromolecular drug carriers. J Natl Cancer Inst 98:330–43
   Google Scholar
• Gabizon AA. (2002). Liposomal drug carrier systems in cancer chemotherapy: current status and future prospects. J Drug Target 10:535–8
   PubMed Web of Science ®Google Scholar
• Green MR, Manikhas GM, Orlov S, et al. (2006). Abraxane®, a novel Cremophor®-free, albumin-bound particle form of paclitaxel for the treatment of advanced non-small-cell lung cancer. Ann Oncol 8:1263–8
   Google Scholar
• Haran G, Cohen R, Bar LK, Barenholz Y. (1993). Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphiphathic weak bases. Biochim Biophys Acta 1151:201–15
   PubMed Web of Science ®Google Scholar
• Hope MJ, Bally MB, Mayer LD, et al. (1986). Generation of multilamellar and unilamellar phospholipid vesicles. Chem Phys Lipids 40:89–108
   Web of Science ®Google Scholar
• Huang C. (1969). Phosphatidylcholine vesicles. Formation and physical characteristics. Biochemistry 8:344–52
   Google Scholar
• Huo S, Ma H, Huang K, et al. (2013). Superior penetration and retention behavior of 50 nm gold nanoparticles in tumors. Cancer Res 73:319–30
   PubMed Web of Science ®Google Scholar
• Jahn A, Stavis SM, Hong JS, et al. (2010). Microfluidic mixing and the formation of nanoscale lipid vesicles. ACS Nano 4:2077–87
   PubMed Web of Science ®Google Scholar
• Jahn A, Vreeland WN, DeVoe DL, et al. (2007). Microfluidic directed formation of liposomes of controlled size. Langmuir 23:6289–93
   PubMed Web of Science ®Google Scholar
• Jain RK, Stylianopoulos T. (2010). Delivering nanomedicine to solid tumors. Nat Rev Clin Oncol 7:653–64
   PubMed Web of Science ®Google Scholar
• Johnston MJ, Edwards K, Karlsson G, Cullis PR. (2008). Influence of drug-to-lipid ratio on drug release properties and liposome integrity in liposomal doxorubicin formulations. J Liposome Res 18:145–57
   PubMed Web of Science ®Google Scholar
• Kano M, Bae Y, Iwata C, et al. (2007). Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumours by inhibition of TGF-β signaling. Proc Natl Acad Sci 104:3460–5
   PubMed Web of Science ®Google Scholar
• Maeda H, Wu J, Sawa T, et al. (2000). Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J Control Release 65:271–84
   PubMed Web of Science ®Google Scholar
• Mayer LD, Tai LC, Ko DSC, et al. (1989). Influence of vesicle size, lipid composition and drug-to-lipid ratio on the biological activity of liposomal doxorubicin. Cancer Res 49:5922–30
   PubMed Web of Science ®Google Scholar
• Perrault SD, Walkey C, Jennings T, et al. (2009). Mediating tumour targeting efficiency of nanoparticles through design. Nano Lett 9:1909–15
   PubMed Web of Science ®Google Scholar
• Semple SC, Chonn A, Cullis PR. (1996). Influence of cholesterol on the association of plasma proteins with liposomes. Biochemistry 35:2521–5
   PubMed Web of Science ®Google Scholar
• Silverman JA, Deitcher SR. (2013). Marqibo® (vincristine sulfate liposome injection) improves the pharmacokinetics and pharmacodynamics of vincristine. Cancer Chemother Pharmacol 71:555–64
   PubMed Web of Science ®Google Scholar
• Unezaki S, Maruyama K, Nagae I, et al. (1996). Direct measurement of the extravasation of polyethyleneglycol-coated liposomes into solid tumor tissue by in vivo fluorescence microscopy. Int J Pharm 144:11–17
   Web of Science ®Google Scholar
• Uster PS, Working PK, Vaage J. (1998). Pegylated liposomal doxorubicin (DOXIL®, CAELYX®) distribution in tumour models observed with confocal laser scanning microscopy. Int J Pharm 162:77–86
   Web of Science ®Google Scholar
• Zhigaltsev IV, Belliveau N, Hafez I, et al. (2012). Bottom-up design and synthesis of limit size lipid nanoparticle systems with aqueous and triglyceride cores using millisecond microfluidic mixing. Langmuir 28:3633–40
   PubMed Web of Science ®Google Scholar
• Zhigaltsev IV, Maurer N, Edwards K, et al. (2006). Formation of drug-arylsulfonate complexes inside liposomes: a novel approach to improve drug retention. J Control Release 110:378–86
   PubMed Web of Science ®Google Scholar