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Research Article

Anticonvulsant Effect of Systemically Administered γ-Aminobutyric Acid (GABA)-Containing Liposomes in Rats Induced to Seizure by Amygdaloid Electrical Stimulation

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Pages 49-55 | Published online: 28 Sep 2008

References

  • Bradford H. F., Dodd P. R. Biochemistry and basic mechanisms in epilepsy. Biochemistry and Neurological Disease. Blackwell, Oxford 1976; 114
  • Hespe H., Roberts E., Prince H. Autoradiographic investigation of [14C]-GABA in tissues of normal and aminooxyacetic acid treated mice. Brain Res. 1969; 14: 663
  • Levi G., Amaldi P., Morisi G. GABA uptake by the developing mouse brain in vivo. Brain Res. 1972; 41: 435
  • Gregoriadis G. The carrier potential of liposomes in biology and medicine. N. Engl. J. Med. 1976; 295: 704
  • Ostro M. J., Cullis P. R. Use of liposomes as injectable delivery systems. Am. J. Hosp. Pharm. 1989; 46: 1576
  • Loeb C., Benassi E., Besio G., Maffini M., Tanganelli P. Liposome-entrapped GABA modifies behavioral and electrographic changes of penicillin-induced epileptic activity. Neurology 1982; 32: 1234
  • Loeb C., Besio G., Mainardi P., Scotto P., Benassi E., Bo G. P. Liposome-entrapped γ-aminobutyric acid inhibits isoniazid-induced epileptogenic activity in rats. Epilepsia 1986; 27: 98
  • Loscher W., Schwark W. S. Evaluation of different GABA receptor agonists in kindled amygdala seizure model in rats. Eur. Neurol. 1985; 89: 454
  • Myslobodsky M. S., Valentein E. S. Amygdaloid kindling and the GABA system. Epilepsia 1989; 32: 281
  • Goddard G. V., McIntyre D. C., Leech C. K. A permanent change in brain resulting from daily electrical stimulation. Exp. Neurol. 1969; 25: 295
  • Racine R. J. Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr. Clin. Neurophysiol. 1972; 32: 281
  • Wada J. A., Sato M. Generalized convulsive seizures induced by daily electrical stimulation of the amygdala in cats: correlative electrographic and behavioral features. Neurology 1974; 24: 565
  • Ellens H., Morselt H., Scherphof G. In vivo fate of large unilamellar sphigomyelin-cholesterol liposomes after intraperitoneal and intravenous injection into rats. Biochim. Biophys. Acta 1981; 674: 10
  • Takada G., Onodera H., Tada K. Delivery of fungal β-galactosidase to rat brain by means of liposomes. Tohoku J. Exp. Med. 1982; 136: 219
  • Yagi K., Naoi M., Sakai M., Abe H., Konishi H., Arichi S. Incorporation of enzyme into brain by means of liposomes of novel composition. J. Appl. Biochem. 1982; 4: 121
  • Hwang K. J., Luk K. F.S., Beaumier P. L. Hepatic uptake and degeneration of unilamellar sphingomyelin/cholesterol liposomes: A kinetic study. Proc. Acad. Sci. U.S.A. 1980; 77: 3030
  • Uemura S., Kimura H. Common epileptic pathway in amygdaloid bicuculline annd electrical kindling demonstrated by transferability. Brain Res. 1990; 537: 315
  • Yokoyama H., Matsumoto S., Mori N., Kumashiro H. Anticonvulsant effect of liposome-entrapped superoxide dismutase in kindled convulsion in rats. Epilepsia 1989; 30: 647
  • Mori N., Ohta S., Kumashiro H. Prolonged antiepileptic effect of liposome-entrapped valproate examined in kindled rats. Epilepsia 1989; 30: 647

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