Repeat Injection Studies of Technetium-99M-Labeled Peg-Liposomes in the Same Animal

References

• Klibanov A., Maruyama K., Torchilin V.P., Huang L. Amphipathic polyethylene glycols effectively prolong the circulation time of liposomes. FEBS Letters. 1990; 268: 235–237
   PubMed Web of Science ®Google Scholar
• Allen T.M., Hansen C., Martin F., Redemann C., Yau-Young A. Liposomes containing synthetic lipid derivative of poly(ethylene) show prolonged circulation half-lives in vivo. Biochim. Biophys. Acta. 1991; 1066: 29–36
   PubMed Web of Science ®Google Scholar
• Senior J., Delgado C., Tilcock C., Gregoriadis G. Influence of surface hydrophilicity of liposomes on their interaction with plasma protein and clearance from the circulation: Studies with poly(ethylene glycol)-coated vesicles. Biochim. Biophys. Acta. 1991; 1062: 77–82
   PubMed Web of Science ®Google Scholar
• Goins B., Phillips W.T., Klipper R. Blood-pool imaging using techne-tium-99m-labeled liposomes. J. Nucl. Med. 1996; 37: 1374–1379
   PubMed Web of Science ®Google Scholar
• Tilcock C., Ahkong Q.F., Fisher D. 99mTc-labeling of lipid vesicles containing the lipophilic chelator PE-Dtta: Effect of tin-to-chelate ratio, chelate content and surface polymer on labeling efficiency and biodistribution behavior. Nucl. Med. Biol. 1994; 21: 89–96
   PubMed Web of Science ®Google Scholar
• Torchilin V.P. Liposomes as delivery agents for medical imaging. Molecular Medicine Today 1996; 2: 242–249
   PubMedGoogle Scholar
• Oyen W.J.G., Boerman O.C., Storm G., van Bloois L., Koenders E.B., Crom-Melin D.J.A., van der Meer J.W.M., Corstens F.H.M. Labelled Stealth® liposomes in experimental infection: An alternative to leukocyte scintigraphy? Nucl. Med. Commun. 1996; 17: 742–748
   Google Scholar
• Allen T.M., Murray L., MacKeigan S., Shah M. Chronic liposome administration in mice: Effects on reticuloendothelial function and tissue distribution. J. Pharm. Exp. Ther. 1984; 229: 267–275
   PubMed Web of Science ®Google Scholar
• Lasic D. Liposomes. Science & Medicine. 1996; 3: 34–43
   Google Scholar
• Mayhew E.G., Lasic D., Babbar S., Martin F.J. Pharmacokinetics and antitumor activity of epirubicin encapsulated in long-circulating liposomes incorporating a polyethylene glycol-derivatized phospholipid. Int. J Cancer 1992; 51: 302–309
   PubMed Web of Science ®Google Scholar
• Vaage J., Mayhew E., Lasic D., Martin F. Therapy of primary and metastatic mouse mammary carcinomas with doxorubicin encapsulated in long circulating liposomes. Int. J. Cancer 1992; 51: 942–948
   PubMed Web of Science ®Google Scholar
• Scherphof G.L. In vivo behavior of liposomes: interactions with mononuclear phagocyte system and implications for drug targeting. “Targeted Drug Delivery.”. Springer-Verlag, New York 1991; 285–327
   Google Scholar
• Smyth H.F., Carpenter C.P., Shaffer C.B. The toxicity of high molecular weight polyethylene glycols: chronic oral and parenteral administration. J. Am. Pharm. Assoc. 1947; 36: 157–160
   Google Scholar
• Working P.K., Dayan A.D. Pharmacological-toxicological expert report Caelyx™ (Stealth® Liposomal Doxorubicin HC1). Human & Experimental Toxicology 1996; 15: 752–785
   Web of Science ®Google Scholar
• Muggia F.M., Hainsworth J.D., Jeffers S., Miller P., Groshen S., Tan M., Roman L., Uziely B., Muderspach L., Garcia A., Burnett A., Greco F.A., Morrow C.P., Paradiso L.J., Liang L.-J. Phase II study of liposomal doxorubicin in refractory ovarian cancer: Antitumor activity and toxicity modification by liposomal encapsulation. Journal of Clinical Oncology 1997; 15: 987–993
   PubMed Web of Science ®Google Scholar
• Perkins A.C., Pimm M.V. Immunologic responses to monoclonal antibodies. “Immunoscintigraphy-Practical Aspects and Clinical Applications.”. Wiley-Liss, New York 1991; 111–128
   Google Scholar
• Phillips W.T., Rudolph A.S., Goins B., Timmons J.H., Klipper R., Blumhardt R. A simple method for producing a technetium-99m-labeled liposome which is stable in vivo. Nucl. Med. Biol. 1992; 19: 539–547
   Web of Science ®Google Scholar
• Rudolph A.S., Klipper R.W., Goins B., Phillips W.T. In vivo biodistribution of a radiolabeled blood substitute: 99mTc-labeled liposome-encapsulated hemoglobin in an anesthetized rabbit. Proceedings National Academy of Science, USA. 1991, 10976–10980
   Google Scholar
• Stewart J.C.M. Colorimetric determination of phospholipids with ammonium ferrothiocyanate. Anal. Biochem. 1980; 104: 10–14
   PubMed Web of Science ®Google Scholar
• Umbreit W.W., Burris R.H., Stauffer J.F. Manometric and Biochemical Techniques. Burgess Publishing, Minneapolis, MN 1972
   Google Scholar
• Goins B., Klipper R., Cliff R.O., Blumhardt R., Phillips W.T. Biodistribution and imaging studies of technetium-99m-labeled liposomes in rats with focal infection. J. Nucl. Med. 1993; 34: 2160–2168
   PubMed Web of Science ®Google Scholar
• Neirinckx R.D., Burke J.F., Harrison R.C., Forster A.M., Andersen A.R., Lassen N.A. The retention mechanism of technetium-99m-Hmpao: intracellular reaction with glutathione. J Cereb Blood Flow Metab. 1988; 8: 504–512
   Web of Science ®Google Scholar
• Ballinger J.R., Gulenchyn K.Y. Technetium-99m-Hmpao stereoisomers: differences in interaction with glutathione. J. Nucl. Med. 1988; 29: 1998–2000
   PubMed Web of Science ®Google Scholar
• Proffitt R.T., Williams L.E., Presant C.A., Tin G.W., Vliana J.A., Gamble R.C., Baldeschwieler J.D. Liposomal blockade of the reticuloendothelial system: Improved tumor imaging with small unilamellar vesicles. Science 1983; 220: 502–505
   PubMed Web of Science ®Google Scholar
• Strauss G., Hauser H. Stabilization of lipid bilayer vesicles by sucrose during freezing. Proc. Natl. Acad. Sci. U.S.A. 1986; 83: 2422–2426
   PubMed Web of Science ®Google Scholar
• Crommelin D.J.A., van Bommel E.M.G. Stability of liposomes on storage: Freeze-dried, frozen or as an aqueous dispersion. Pharm. Res 1984; 159–163
   PubMed Web of Science ®Google Scholar
• Crowe J.H., Crowe L.M., Carpenter J.H., Rudolph A.S., Wistrom C.A., Spargo B.J., Anchordoguy T.J. Interactions of sugars with membranes. Biochim. Biophys. Acta. 1988; 947: 367–384
   PubMed Web of Science ®Google Scholar
• Szucs M., Tilcock C. Lyophilization and rehydration of polymer-coated lipid vesicles containing a lipophilic chelator in the presence of sucrose: Labeling with 99mTc and biodistribution studies. Nucl. Med. Biol. 1995; 22: 263–268
   PubMed Web of Science ®Google Scholar