417
Views
42
CrossRef citations to date
0
Altmetric
Original Article

Pars Plana Vitrectomy versus Immunomodulatory Therapy for Intermediate Uveitis: A Prospective, Randomized Pilot Study

, MD, , MD, , BS, , MD, , MD & , MD, FACS
Pages 411-417 | Received 31 Mar 2010, Accepted 10 Jun 2010, Published online: 25 Aug 2010

REFERENCES

  • Jabs DA, Nussenblatt RB, Rosenbaum JT. Standardization of Uveitis Nomenclature (SUN) Working Group. Standardization of uveitis nomenclature for reporting clinical data: results of the First International Workshop. Am J Ophthalmol. 2005;140:509–516.
  • Boyd SR, Young S, Lightman S. Immunopathology of the Noninfectious Posterior and Intermediate Uveitides. Surv Ophth. 2001;46:209–233.
  • Bonfioli AA, Damico FM, Curi AL, Orefice F. Intermediate uveitis. Semin Ophthalmol. 2005;20:147–154.
  • Zierhut M, Vitale A. Intermediate uveitis. In: Foster CS, Vitale A, eds. Diagnosis and Treatment of Uveitis. Philadelphia, PA: WB Saunders;2001:844–857.
  • Nolle B, Eckardt C. Cellular phenotype of vitreous cells in intermediate uveitis. Dev Ophthalmol. 1992;23:145–149.
  • Kaplan HJ. Surgical treatment of intermediate uveitis. Dev Ophthalmol. 1992;23:185–189.
  • Kanski JJ, Shun-Shin A. Systematic uveitis syndromes in childhood; an analysis of 340 cases. Ophthalmology. 1984;91:1247–1252.
  • Holland GN. The enigma of pars planitis, revisited. Am J Ophthalmol. 2006;141:729–730.
  • Becker M, Davis J. Vitrectomy in the treatment of uveitis. Am J Ophthalmol. 2005;140:1096–1105.
  • Stavrou P, Baltatzis S, Letko E, Samson CM, Christen W, Foster CS. Pars plana vitrectomy in patients with intermediate uveitis. Ocul Immunol Inflamm. 2001;9:141–151.
  • Harper SL, Chorich III LJ, Foster CS. Diagnosis of uveitis. In: Foster CS, Vitale A, eds. Diagnosis and Treatment of Uveitis. Philadelphia, PA: WB Saunders; 2001:79–103.
  • Brockhurst RJ, Schepens CL; Uveitis IV. Peripheral uveitis: the complication of retinal detachment. Arch Ophthalmol. 1968;80:747–753.
  • Lemos SR, Orefice F. Uveite intermediaria. In: Orefice, F. Uveıtes—Clınica e Cirurgica. Rio de Janeiro: Editorial Cultura Medica; 2000;843–859.
  • Lai WW, Pulido JS. Intermediate uveitis. Ophthalmol Clin N Am. 2002;15:309–317.
  • Mieler WF, Aaberg TM. Vitreous surgery in the management of peripheral uveitis. Dev Ophthalmol. 1992; 23:239–250.
  • Heimann K, Schmanke L, Brunner R, Amerian B. Pars plana vitrectomy in the treatment of chronic uveitis. Dev Ophthalmol. 1992; 23:196–203.
  • Eckardt C, Bacskulin A. Vitrectomy in intermediate uveitis. Dev Ophthalmol. 1992; 23:232–238.
  • Heiligenhaus A, Bornfeld N, Foerster MH, Wessing A. Long-term results of pars plana vitrectomy in the management of complicated uveitis. Br J Ophthalmol. 1994;78:549–5454.
  • Scott RA, Haynes RJ, Orr GM, Cooling RJ, Pavesio CE, Charteris DG. Vitreous surgery in the management of chronic endogenous posterior uveitis. Eye. 2003;17:221–227.
  • Wiechens B, Reichelt JA, Urbat C, Nolle B. Pars plana vitrectomy in cystoid macular edema of different forms of chronic uveitis. Ophthalmologe. 2003;100:33–43.
  • Potter MJ, Myckatyn SO, Maberley AL, Lee AS. Vitrectomy for pars planitis complicated by vitreous hemorrhage: visual outcome and long-term follow-up. Am J Ophthalmol. 2001;131:514–515.
  • Dev S, Mieler WF, Pulido JS, Mittra RA. Visual outcomes after pars plana vitrectomy for epiretinal membranes associated with pars planitis. Ophthalmology. 1999;106:1086–1090.
  • Heiligenhaus A, Bornfeld N, Wessing A. Long-term results of pars plana vitrectomy in the management of intermediate uveitis. Curr Opin Ophthalmol. 1996;7:77–79.
  • Bacskulin A, Eckardt C. Ergebnisse der pars plana-Vitrektomie. Ophthalmologe. 1993;90:434–439.
  • Diamond JG, Kaplan HJ. Lensectomy and vitrectomy for complicated cataract secondary to uveitis. Arch Ophthalmol. 1978;96:1798–1804.
  • Trittibach P, Koerner F, Sarra GM, Garweg JG. Vitrectomy for juvenile uveitis: prognostic factors for the long-term functional outcome. Eye. 2006;20:184–190.
  • Bloch ME, Nussenblatt RB. International Uveitis Study Group recommendations for the evaluation of intraocular inflammatory disease. Am J Ophthalmol. 1987;103:234–235.
  • Tugal-Tutkun I, Havrlikova K, Power WJ, Foster CS. Changing patterns in uveitis of childhood. Ophthalmology. 1996;103:375–383.
  • Wong VG, Hersh EM: Methotrexate in the treatment of cyclitis. Trans Am Acad Arch Ophthalmol Otolaryngol. 1965;69:279–293.
  • Rubin B, Palestine AG. Complications of corticosteroid and immunosuppressive drugs. Int Ophthalmol Clin. 1989;29:159–171.
  • Walton RC, Nussenblatt RB, Whitcup SM. Cyclosporine therapy for severe sight-threatening uveitis in children and adolescents. Ophthalmology. 1998;105:2028–2034.
  • Nussenblatt RB, Palestine AG, Chan CC. Cyclosporine therapy for uveitis: long-term followup. J Ocul Pharmacol. 1985;1:369–382.
  • Schlote T, Dannecker G, Thiel HJ, Zierhut M: Cyclosporin A in der Therapie der chronischen Uveitis im Kindesalter. Ophthalmologe. 1996;93:745–748.
  • Cimino L, Finzi G, Mora P, Zavota L, Gandolfi SA, Orsoni JG. Effect of a drug combination treatment on ocular perfusion in recurrent idiopathic intermediate uveitis. Ocul Immunol Inflamm. 2003;11:299–303.
  • Greiner K, Varikkara M, Santiago C, Forrester JV. Efficiency of mycophenolate mofetil in the treatment of intermediate and posterior uveitis. Ophthalmologe. 2002;99:691–694.
  • Kilmartin DJ, Fletcher ZJ, Almeida JA, Liversidge J, Forrester JV, Dick AD. CD69 expression on peripheral CD4+ T cells parallels disease activity and is reduced by mycophenolate mofetil therapy in uveitis. Invest Ophthalmol Vis Sci. 2001;42:1285–1292.
  • Menezo V, Lau C, Comer M, Lightman S. Clinical outcome of chronic immunosuppression in patients with non-infectious uveitis. Clin Exp Ophthalmol. 2005;33:16–21.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.