282
Views
22
CrossRef citations to date
0
Altmetric
Controversy

Controversies in Ocular Inflammation and Immunology Laser Flare Photometry

, MD, PhD, , MD, PhD, , MD, PhD & , MD, PhD
Pages 334-340 | Received 30 Jul 2010, Accepted 30 Jul 2010, Published online: 17 Sep 2010

SELECTIVE REFERENCES

  • Biziorek B, Zarnowski T, Zagórski Z. Evaluation and monitoring of selected inflammation patterns in uveitis using laser tyndallometry. Klin Oczna. 2000;102:169–172. Laser tyndallometry has been proven to be a useful tool for the objective and quantitative evaluation of anterior chamber flare in uveitis and for monitoring the effectiveness of the treatment.
  • Guex-Crosier Y, Pittet N, Herbort CP. Evaluation of laser flare-cell photometry in the appraisal and management of intraocular inflammation in uveitis. Ophthalmology. 1994;101:728–735. The authors show that laser flare cell photometry allows quantitative assessment of inflammation in uveitis and contributes to improved management of patients with uveitis.
  • Tugal-Tutkun I, Herbort CP. Laser flare photometry: a noninvasive, objective, and quantitative method to measure intraocular inflammation. Int Ophthalmol 30. doi: 10.1007/s10792-009-9310-2. Relationship between laser flare photometry and complications of uveitis and visual loss.
  • Davis JL, Dacanay LM, Holland GN, Berrocal AM, Giese MJ, Feuer WJ. Laser flare photometry and complications of chronic uveitis in children. Am J Ophthalmol. 2003, 135:763–771. There is a positive relationship between laser flare photometry values and the prevalence of complications of uveitis in children. Laser flare photometry provides a novel way to monitor children with uveitis.
  • Nguyen NX, Amann T, Küchle M. Laser-tyndallometry in eyes with acute retinal necrosis syndrome. Erlanger Laser Tyndallometry Study Group. Klin Monbl Augenheilkd. 1998;213:197–200. Measurement with the laser flare cell meter allows quantification of blood–ocular barrier breakdown in eyes with ARN and may be useful for monitoring inflammatory activity during treatment.
  • Ikeji F, Pavesio C, Bunce C, White E. Quantitative assessment of the effects of pupillary dilation on aqueous flare in eyes with chronic anterior uveitis using laser flare photometry. Int Ophthalmol 30. 2010 doi:10.1007/s10792-010-9373-0. This study showed little evidence of any systematic difference between dilated and undilated flare measurements. The measurement of flare was not affected by the dilation of the pupil and measurements could be taken before or after papillary dilation.
  • Holland GN. A reconsideration of anterior chamber flare and its clinical relevance for children with chronic anterior uveitis (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc. 2007;105:344–364. Flare may be useful in the evaluation and management of chronic anterior uveitis in children. Flare is a marker of disease severity and is predictive of adverse events during the course of disease.
  • Guex-Crosier Y, Pittet N, Herbort CP. Sensitivity of laser flare photometry to monitor inflammation in uveitis of the posterior segment. Ophthalmology. 1995;102:613–621. Laser flare photometry was found to be a very sensitive monitor of inflammation in uveitis of the posterior segment as long as a sufficient level of associated blood-aqueous barrier disruption (flare) was present.
  • Küchle M, Nguyen NX, Naumann GO. Tyndallometry with the laser flare cell meter in intraocular inflammation. Ophthalmologe. 1994;91:219–223. Measurement of aqueous flare with the LFCM is a noninvasive examination that yields objective, quantitative, and reproducible results and therefore has advantages over slit-lamp assessment.
  • Tugal-Tutkun I, Cingü K, Kir N, Yeniad B, Urgancioglu M, Gül A. Use of laser flare-cell photometry to quantify intraocular inflammation in patients with Behçet uveitis. Graefes Arch Clin Exp Ophthalmol. 2008;246:1169–1177. Laser flare cell photometry is a useful objective method in the quantitative assessment of intraocular inflammation in patients with Behçet uveitis. The use of this quantitative technique in clinical trials of Behçet uveitis may provide comparable data, as it gives an objective measure of intraocular inflammation.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.