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Ocular Immunology and Inflammation Volume 24, 2016 - Issue 5
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Original Articles

Evaluation of Intracameral Amphotericin B in the Management of Fungal Keratitis: Randomized Controlled Trial

Namrata SharmaRajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India and Correspondence[email protected]
, MD,
Preeti SankaranRajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India and
, MD,
Tushar AgarwalRajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India and
, MD,
Tarun AroraRajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India and
, MD,
Bhavna ChawlaRajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India and
, MD,
Jeewan S TitiyalRajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India and
, MD,
Radhika TandonRajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India and
, MD,
Gita SatapathyRajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India and
, MD &
Rasik B VajpayeeRajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India and ;Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia
, MS, FRCS (Edin), FRANZCO show all
Pages 493-497 | Received 25 Dec 2014, Accepted 29 May 2015, Published online: 23 Sep 2015

References

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  • Sony P, Sharma N, Sen S, et al. Indications of penetrating keratoplasty in northern India. Cornea. 2005;24:989–991
  • Bharathi MJ, Ramakrishnan R, Meenakshi R, et al. Microbial keratitis in South India: influence of risk factors, climate, and geographical variation. Ophthalmic Epidemiol. 2007;14:61–69
  • Kaushik S, Ram J, Brar GS, et al. Intracameral Amphotericin B: initial experience in severe keratomycosis. Cornea. 2001;20:715–719
  • Kuriakose T, Kothari M, Paul P, et al. Intracameral amphotericin B injection in the management of deep keratomycosis. Cornea. 2002;21:653–656
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  • Bharadwaj PC, Shrivastava KN, Lall K, et al. Intracameral injections of framycetin sulfate (soframycin) in fulminating corneal infections. A clinical trial. Br J Ophthalmol. 1969;53:185–187
  • Wang HZ, Chang CH, Lin CP, et al. Using MTT viability assay to test the cytotoxicity of antibiotics and steroid to cultured porcine corneal endothelial cells. J Ocul Pharmacol Ther. 1996;12:35–43
  • Chang CH, Lin CP, Wang HZ. Cytotoxicity of intracameral injection drugs to corneal endothelium as evaluated by corneal endothelial cell culture. Cornea. 1995;14:71–76
  • Vajpayee RB, Angra SK, Sandramouli S, et al. Laboratory diagnosis of keratomycosis: comparative evaluation of direct microscopy and culture results. Ann Ophthalmol. 1993;25:68–71
  • Bharathi MJ, Ramakrishnan R, Meenakshi R, et al. Microbiological diagnosis of infective keratitis: comparative evaluation of direct microscopy and culture results. Br J Ophthalmol. 2006;90:1271–1276
  • Sharma S, Kunimoto DY, Gopinathan U, et al. Evaluation of corneal scraping smear examination methods in the diagnosis of bacterial and fungal keratitis: a survey of eight years of laboratory experience. Cornea. 2002;21:643–647
  • Sharma S, Silverberg M, Mehta P, et al. Early diagnosis of mycotic keratitis: predictive value of potassium hydroxide preparation. Indian J Ophthalmol. 1998;46:31–35
  • Shao Y, Yu Y, Pei CG, et al. Therapeutic efficacy of intracameral amphotericin B injection for 60 patients with keratomycosis. Int J Ophthalmol. 2010;3:257–260

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