341
Views
12
CrossRef citations to date
0
Altmetric
Art/Ivf

Impact of high basal FSH/LH ratio in women with normal FSH levels on in vitro fertilization outcomes

, , , , &
Pages 424-429 | Received 23 Mar 2011, Accepted 15 Oct 2012, Published online: 12 Feb 2013

References

  • Ho JY-P, Guu HF, Yi YL, et al. The serum follicle-stimulating hormone-to-luteinizing hormone ratio at the start of stimulation with gonadotropins after pituitary down-regulation is inversely correlated with a mature oocyte yield and can predict “low responders”. Fertil Steril 2005;83:883–8
  • Surrey ES, Schoolcraft WB. Evaluating strategies for improving ovarian response of the poor responder undergoing assisted reproductive techniques. Fertil Steril 2000;73:667–76
  • van Rooij IA, Broekmans FJ, te Velde ER, et al. Serum anti-mullerian hormone levels: a novel measure of ovarian reserve. Hum Reprod 2002;17:3065–71
  • Noci I, Biagiotti R, Maggi M, et al. Low day 3 luteinizing hormone values are predictive of reduced response to ovarian stimulation. Hum Reprod 1998;13:531–4
  • Barroso G, Oehninger S, Monzo A, et al. High FSH:LH ratio and low LH levels in basal cycle day 3: impact on follicular development and IVF outcome. J Assist Reprod Gen 2001;18:499–505
  • Smotrich DB, Widra EA, Gnidoff PR, et al. Prognostic value of day 3 estradiol on in vitro fertilization outcome. Fertil Steril 1995;64:1136–40
  • Bancsi LF, Broekmans FJ, Eijkemans MJ, et al. Predictors of poor ovarian response in in vitro fertilization: a prospective study comparing basal markers of ovarian reserve. Fertil Steril 2002;77:328–36
  • Sherman BM, Korenman SG. Hormonal characteristics of the human menstrual cycle throughout reproductive life. J Clin Invest 1975;55:699–706
  • Luna M, Grunfeld L, Mukherjee T, et al. Moderately elevated levels of basal follicle-stimulating hormone in young patients predict low ovarian response, but should not be used to disqualify patients from attempting in vitro fertilization. Fertil Steril 2007;87:782–7
  • Broekmans FJ, Kwee J, Hendriks DJ, et al. A systematic review of tests predicting ovarian reserve and IVF outcome. Hum Reprod Update 2006;12:685–718
  • Taymor ML. The regulation of follicle growth: some clinical implications in reproductive endocrinology. Fertil Steril 1996;65:235–47
  • Mukherjee T, Copperman AB, Lapinski R, et al. An elevated day three follicle-stimulating hormone:luteinizing hormone ratio (FSH:LH) in the presence of a normal day 3 FSH predicts a poor response to controlled ovarian hyperstimulation. Fertil Steril 1996;65:588–93
  • Orvieto R, Homburg R, Meltcer S, et al. HMG improves IVF outcome in patients with high basal FSH/LH ratio: a preliminary study. Reprod Biomed Online 2009;18:205–8
  • Liu KE, Greenblatt EM. Elevated day 3 follicle-stimulating hormone/luteinizing hormone ratio >or= 2 is associated with higher rates of cancellation in in vitro fertilization-embryo transfer cycles. Fertil Steril 2008;90:297–301
  • Shrim A, Elizur SE, Seidman DS, et al. Elevated day 3 FSH/LH ratio due to low LH concentrations predicts reduced ovarian response. Reprod Biomed Online 2006;12:418–22
  • Hillier SG. The Parkes lecture: controlled ovarian stimulation in women. J Reprod Fertil 2000;120:201–10
  • Platteau P, Smitz J, Albano C, et al. Exogenous luteinizing hormone activity may influence the treatment outcome in in vitro fertilization but not in intracytoplasmic sperm injection cycles. Fertil Steril 2004;81:1401–4
  • Gomez-Palomares JL, Acevedo-Martin B, Andres L, et al. LH improves early follicular recruitment in women over 38 years old. Reprodu Biomed Online 2005;11:409–14
  • Fleming R, Rehka P, Deshpande N, et al. Suppression of LH during ovarian stimulation: effects differ in cycles stimulated with purified urinary FSH and recombinant FSH. Hum Reprod 2000;15:1440–5
  • Orvieto R, Meltzer S, Pabinson J, et al. Does day 3 luteinizing-hormone level predict IVF success in patients undergoing controlled ovarian stimulation with GnRH analogues? Fertil Steril 2008;90:1297–300
  • De Placido G, Alviggi C, Perino A, et al. Recombinant human LH supplementation versus recombinant human FSH (rFSH) step-up protocol during controlled ovarian stimulation in normogonadotrophic women with initial inadequate ovarian response to rFSH. A multicentre, prospective, randomized controlled trial. Hum Reprod 2005;20:390–6
  • Kolibianakis EM, Kalogeropoulou L, Griesinger G, et al. Among patients treated with FSH and GnRH analogues for in vitro fertilization, is the addition of recombinant LH associated with the probability of live birth? A systematic review and meta-analysis. Hum Reprod Update 2007;13:445–52
  • Mochtar MH, Vandr Veeh, Ziech M, et al. Recombinant Luteinizing Hormone (rLH) for controlled ovarian hyperstimulation in assisted reproductive cycles. Cochrane Database Syst Rev 2007;18:CD005070

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.