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Factor V Mutation

Validation of the minisequencing method for detection of G1691A (Leiden) factor V mutation

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Pages 319-322 | Received 06 Oct 2011, Accepted 09 Oct 2012, Published online: 21 Dec 2012

References

  • PN/EN ISO/IEC 17025:2005
  • PN/EN ISO/IEC 15189:2008
  • Laczmanska I, Pesz K, Laczmanski L. Application of selected methods based on the polymerase chain reaction in medical molecular diagnostics. Adv Clin Exp Med 2009;18:85–92
  • Segers K, Dahlback B, Nicolaes GAF. Coagulation factor V and thrombophilia: background and mechanisms. Thromb Haemost 2007;98:530–42
  • Ridker PM, Miletich JP, Hennekens CH, et al. Ethnic distribution of Factor V leiden in 4047 men and women. Implications for venous thrombosis screening. JAMA 1997;277:1305–7
  • Laczmanski L, Laczmanska I. Validation of diagnostic test in molecular genetics. Diagn Lab 2009;45:163–5

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