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Review Article

Selective progesterone receptor modulators: a class with multiple actions and applications in reproductive endocrinology, and gynecology

Pages 683-684 | Received 23 Jul 2014, Accepted 29 Jul 2014, Published online: 22 Sep 2014

References

  • Bouchard P, Chabbert-Buffet N, Fauser BC. Selective progesterone receptor modulators in reproductive medicine: pharmacology, clinical efficacy and safety. Fertil Steril 2011;96:1175–89
  • Chabbert-Buffet N1, Pintiaux A, Bouchard P. The imminent dawn of SPRMs in obstetrics and gynecology. Mol Cell Endocrinol 2012;358:232–43
  • Kasa-Vubu JZ1, Dahl GE, Evans NP, et al. Progesterone blocks the estradiol-induced gonadotropin discharge in the ewe by inhibiting the surge of gonadotropin-releasing hormone. Endocrinology 1992;131:208–12
  • Skinner DC, Evans NP, Delaleu B, et al. The negative feedback actions of progesterone on gonadotropin-releasing hormone secretion are transduced by the classical progesterone receptor. Proc Natl Acad Sci USA 1998;95:10978–83
  • Baird DT, Thong KJ, Hall C, Cameron ST. Failure of oestrogen induced luteinizing hormone surge in women treated with mifepristone (RU 486) every day for 30 days. Hum Reprod 1995;10:2270–6
  • Chabbert-Buffet N, Pintiaux-Kairis A, Bouchard P; VA2914 Study Group. Effects of the progesterone receptor modulator VA2914 in a continuous low dose on the hypothalamic-pituitary-ovarian axis and endometrium in normal women: a prospective, randomized, placebo-controlled trial. J Clin Endocrinol Metab 2007;92:3582–9
  • Nallasamy S, Kim J, Sitruk Ware R, et al. Ulipristal Blocks ovulation by inhibiting progesterone receptor-dependent pathways intrinsic to the ovary. Reprod Sci 2012;20:371–81
  • Brache V, Cochon L, Deniaud M, Croxatto HB. Ulipristal acetate prevents ovulation more effectively than levonorgestrel: analysis of pooled data from three randomized trials of emergency contraception regimens. Contraception 2013;88:611–18
  • Bouchard P. Current and future medical treatments for menometrorrhagia during the premenopause. Gynecol Endocrinol 2011;27:1120–5
  • Donnez J, Tatarchuk TF, Bouchard P, et al.; PEARL I Study Group. Ulipristal acetate versus placebo for fibroid treatment before surgery. N Engl J Med 2012;366:409–20
  • Donnez J, Vázquez F, Tomaszewski J, et al.; PEARL III and PEARL III Extension Study Group. Long-term treatment of uterine fibroids with ulipristal acetate. Fertil Steril 2014;101:1565–73

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