Endogenous thrombin potential in polycystic ovary syndrome: the association to body mass index, insulin resistance, and inflammation

References

• Fauser BCJM, Tarlatzis BC, Rebar RW, et al. Consensus on women’s health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group. Fertil Steril 2012;97:28–38.e25
   PubMed Web of Science ®Google Scholar
• Azziz R. Controversy in clinical endocrinology: diagnosis of polycystic ovarian syndrome: the Rotterdam criteria are premature. J Clin Endocrinol Metab 2006;91:781–5
   PubMed Web of Science ®Google Scholar
• Azziz R, Carmina E, Dewailly D, et al. The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report. Fertil Steril 2009;91:456–88
   PubMed Web of Science ®Google Scholar
• Tziomalos K, Katsikis I, Papadakis E, et al. Comparison of markers of insulin resistance and circulating androgens between women with polycystic ovary syndrome and women with metabolic syndrome. Hum Reprod Oxf Engl 2013;28:785–93
   PubMed Web of Science ®Google Scholar
• Aziz M, Sidelman JJ, Faber J, et al. Polycystic ovary syndrome: insulin resistance and low-grade inflammation according to phenotypes. 1st Nordic Congress on Obesity in Gynaecology and Obstetrics (NOCOGO), 22–24 October 2012, Billund, Denmark
   Google Scholar
• Bird ST, Hartzema AG, Brophy JM, et al. Risk of venous thromboembolism in women with polycystic ovary syndrome: a population-based matched cohort analysis. CMAJ Can Med Assoc J Assoc Medicale Can 2013;185:E115–20
   PubMed Web of Science ®Google Scholar
• Okoroh EM, Hooper WC, Atrash HK, et al. Is polycystic ovary syndrome another risk factor for venous thromboembolism? United States, 2003–2008. Am J Obstet Gynecol 2012;207:377
   PubMed Web of Science ®Google Scholar
• Hemker HC, Al Dieri R, De Smedt E, Béguin S. Thrombin generation, a function test of the haemostatic-thrombotic system. Thromb Haemost 2006;96:553–61
   PubMed Web of Science ®Google Scholar
• Van Hylckama Vlieg A, Christiansen SC, Luddington R, et al. Elevated endogenous thrombin potential is associated with an increased risk of a first deep venous thrombosis but not with the risk of recurrence. Br J Haematol 2007;138:769–74
   PubMed Web of Science ®Google Scholar
• Aziz M, Naver KV, Wissing MLM, et al. Polycystic ovary syndrome: infertility, cardiovascular, metabolic and obstetrical risks, laboratory and clinical outcomes – the PICOLO Study. Gynecol Endocrinol Off J Int Soc Gynecol Endocrinol 2012;28:253–8
   PubMed Web of Science ®Google Scholar
• Aziz M, Wissing MLM, Naver KV, et al. Polycystic ovary syndrome and low-grade inflammation with special reference to YKL-40. Gynecol Endocrinol 2014;30:311–15
   PubMed Web of Science ®Google Scholar
• Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod Oxf Engl 2004;19:41–7
   PubMed Web of Science ®Google Scholar
• Rosenfield RL. Clinical practice. Hirsutism. N Engl J Med 2005;353:2578–88
   PubMed Web of Science ®Google Scholar
• Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28:412–19
   PubMed Web of Science ®Google Scholar
• Novotny R, Going S, Teegarden D, et al. Hispanic and Asian pubertal girls have higher android/gynoid fat ratio than whites. Obes Silver Spring Md 2007;15:1565–70
   PubMed Web of Science ®Google Scholar
• Baglin T. The measurement and application of thrombin generation. Br J Haematol 2005;130:653–61
   PubMed Web of Science ®Google Scholar
• Besser M, Baglin C, Luddington R, et al. High rate of unprovoked recurrent venous thrombosis is associated with high thrombin-generating potential in a prospective cohort study. J Thromb Haemost JTH 2008;6:1720–5
   PubMed Web of Science ®Google Scholar
• Sørensen HT, Horvath-Puho E, Pedersen L, et al. Venous thromboembolism and subsequent hospitalisation due to acute arterial cardiovascular events: a 20-year cohort study. Lancet 2007;370:1773–9
   PubMed Web of Science ®Google Scholar
• Lijfering WM, Flinterman LE, Vandenbroucke JP, et al. Relationship between venous and arterial thrombosis: a review of the literature from a causal perspective. Semin Thromb Hemost 2011;37:885–96
   PubMed Web of Science ®Google Scholar
• Beijers HJBH, Ferreira I, Spronk HMH, et al. Body composition as determinant of thrombin generation in plasma: the Hoorn study. Arterioscler Thromb Vasc Biol 2010;30:2639–47
   PubMed Web of Science ®Google Scholar
• Prüller F, Raggam RB, Posch V, et al. Trunk weighted obesity, cholesterol levels and low grade inflammation are main determinants for enhanced thrombin generation. Atherosclerosis 2012;220:215–18
   PubMed Web of Science ®Google Scholar
• De Mendonça-Louzeiro MRMF, Annichino-Bizzacchi JM, Magna LA, et al. Faster thrombin generation in women with polycystic ovary syndrome compared with healthy controls matched for age and body mass index. Fertil Steril 2013;99:1786–90
   PubMed Web of Science ®Google Scholar
• Hioki H, Aoki N, Kawano K, et al. Acute effects of cigarette smoking on platelet-dependent thrombin generation. Eur Heart J 2001;22:56–61
   PubMed Web of Science ®Google Scholar
• Kebapcilar L, Taner CE, Kebapcilar AG, Sari I. High mean platelet volume, low-grade systemic coagulation and fibrinolytic activation are associated with androgen and insulin levels in polycystic ovary syndrome. Arch Gynecol Obstet 2009;280:187–93
   PubMed Web of Science ®Google Scholar
• Yildiz BO, Haznedaroğlu IC, Kirazli S, Bayraktar M. Global fibrinolytic capacity is decreased in polycystic ovary syndrome, suggesting a prothrombotic state. J Clin Endocrinol Metab 2002;87:3871–5
   PubMed Web of Science ®Google Scholar
• Lemieux I, Pascot A, Prud’homme D, et al. Elevated C-reactive protein: another component of the atherothrombotic profile of abdominal obesity. Arterioscler Thromb Vasc Biol. Juni 2001;21:961–7
   PubMed Web of Science ®Google Scholar