296
Views
7
CrossRef citations to date
0
Altmetric
G-Protein Coupled ER and Leiomyoma Cells

G protein-coupled estrogen receptor 1 (GPER 1) mediates estrogen-induced, proliferation of leiomyoma cells

, , , , &
Pages 894-898 | Received 30 Dec 2014, Accepted 05 Sep 2015, Published online: 29 Sep 2015

References

  • Owman, C, Blay, P, Nilsson, C, Lolait, SJ. Cloning of human cDNA encoding a novel heptahelix receptor expressed in Burkitt’s lymphoma and widely distributed in brain and peripheral tissues. Biochem Biophys Res Commun 1996;228:285–92
  • O’Dowd BF, Nguyen T, Marchese A, et al. Discovery of three novel G-protein-coupled receptor genes. Genomics 1998;47:310–13
  • Filardo EJ, Quinn JA, Bland KI, Frackelton JAR. Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF. Mol Endocrinol 2000;14:1649–60
  • Filardo EJ, Thomas P. Minireview: G protein-coupled estrogen receptor-1, GPER-1: its mechanism of action and role in female reproductive cancer, renal and vascular physiology. Endocrinology 2012;153:2953–62
  • Imesch P, Samartzis EP, Dedes KJ, et al. Histone deacetylase inhibitors down-regulate G-protein-coupled estrogen receptor and the GPER-antagonist G-15 inhibits proliferation in endometriostic cells. Fertil Steril 2013;100:770–6
  • Filardo EJ, Thomas, P. Minireview: G protein-coupled estrogen receptor-1, GPER-1: its mechanism of action and role in female reproductive cancer, renal and vascular physiology. Endocrinology 2012;153:2953–62
  • Lindsey SH, Yamaleyeva LM, Brosnihan KB, et al. Estrogen receptor GPR30 reduces oxidative stress and proteinuria in the salt-sensitive female mRen2.Lewis rat. Hypertension 2011;58:665–71
  • Barton M. Cholesterol and atherosclerosis: modulation by oestrogen. Curr Opin Lipidol 2013;24:214–20
  • Rettberg JR, Yao J, Brinton RD. Estrogen: a master regulator of bioenergetic systems in the brain and body. Front Neuroendocrinol 2014;35:8–30
  • Ge X, Guo R, Qiao Y, et al. The G protein-coupled receptor GPR30 mediates the nontranscriptional effect of estrogen on the activation of PI3K/Akt pathway in endometrial cancer cells. Int J Gynecol Cancer 2013;23:52–9
  • Wang C, Lv X, Jiang C, Davis JS. The putative G-protein coupled estrogen receptor agonist G-1 suppresses proliferation of ovarian and breast cancer cells in a GPER-independent. Am J Transl Res 2012;4:390–402
  • King WJ, Greene GL. Monoclonal antibodies localize oestrogen receptor in the nuclei of target cells. Nature 1984;307:745–7
  • Lappano R, Maggiolim M. G protein-coupled receptors: novel targets for drug discovery in cancer. Nature Rev Drug Discov 2011;10:47–60
  • Daub H, Weiss FU, Wallasch C, Ullrich A. Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors. Nature 1996;379:557–60
  • Shang Y. Molecular mechanisms of oestrogen and SERMs in endometrial Carcinogenesis. Nat Rev Cancer 2006;6:360–8
  • Tian R, Zengyong W, Zhan S, et al. Differential expression of G-protein-coupled estrogen receptor-30 in human myometrial and uterine leiomyoma smooth muscle. Fertil Steril 2013;99:256–80
  • Klintman M, Strand C, Ahlin C, et al. The prognostic value of mitotic activity index (MAI), phosphohistone H3 (PPH3), cyclin B1, cyclin A, and Ki67, alone and in combinations, in node-negative premenopausal breast cancer. PLoS One 2013;8:e81902
  • Fung AD, Cohen C, Kavuri S, et al. Phosphohistone H3 and Ki-67 labeling indices in cytologic specimens from well-differentiated neuroendocrine tumors of the gastrointestinal tract and pancreas: a comparative analysis using automated image cytometry. Acta Cytol 2013;57:501–8
  • Tetzlaff MT, Curry JL, Ivan D, et al. Immunodetection of phosphohistone H3 as a surrogate of mitotic figure count and clinical outcome in cutaneous melanoma. Mod Pathol 2013;26:1153–60
  • Matthias B. Position paper: the membrane estrogen receptor GPER – clues and questions. Steroids 2012;77:935–42
  • Jiang XX, Xu KH, Ma JY, et al. Reduced migration of Ishikawa cells associated with downregulation of aquaporin-5. Oncol Lett 2012;4:257–61
  • Wang C, Lv X, Jiang C, Davis JS. The putative G-protein coupled estrogen receptor agonist G-1 suppresses proliferation of ovarian and breast cancer cells in a GPER-independent. Am J Transl Res 2012;4:390–402
  • Eric R. P, Matthias B. Estrogen biology: new insights into GPER function and clinical opportunities. Mol Cell Endocrinol 2014;389:71–83
  • Xu XL, Lin J, Jiang XX, et al. Expression of GPR30 in leiomyoma cells of uterus and its relation to cell proliferation. J Pract Oncol 2014;29:234–37
  • Thomas P, Pang Y, Filardo EJ, Dong J. Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 2005;146:624–32
  • Boulware MI, Weick JP, Becklund BR, et al. Estradiol activates group I and II metabotropic glutamate receptor signaling, leading to opposing influences on cAMP response element-binding protein. J Neurosci 2005;25:5066–78
  • Bartella V, Marco DP, Malaguamera R, et al. New advances on the functional cross-talk between insulin-like growth factor-1 and estrogen signaling in cancer. Cell Signal 2012;24:1515–21
  • Ge X, Guo R, Qiao Y, et al. The G protein-coupled receptor GPR30 mediates the nontranscriptional effect of estrogen on the activation of PI3K/Akt pathway in endometrial cancer cells. Int J Gynecol Cancer 2013;23:52–9
  • Idriss MH, Kazlouskaya V, Malhotra S, et al. Phosphohistone-H3 and Ki-67 immunostaining in cutaneous pilar leiomyoma and leiomyosarcoma (atypical intradermal smooth muscle neoplasm). J Cutan Pathol 2013;40:557–63
  • Andersen J. Factors in fibroid growth. Baillieres Clin Obstet Gynaecol 1998;12:225–43

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.