Levothyroxine liquid solution versus tablet form for replacement treatment in pregnant women

References

• Garber JR, Cobin RH, Gharib H, et al. Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association. Endocr Pract 2012;18:988–1028
   PubMed Web of Science ®Google Scholar
• Stagnaro-Green A, Abalovich M, Alexander E, et al. Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum. Thyroid 2011;21:1081–125
   PubMed Web of Science ®Google Scholar
• De Groot L, Abalovich M, Alexander EK, et al. Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2012;97:2543–65
   PubMed Web of Science ®Google Scholar
• Lazarus J, Brown RS, Daumerie C, et al. 2014 European thyroid association guidelines for the management of subclinical hypothyroidismin pregnancy and in children. Eur Thyroid J 2014;3:76–94
   PubMedGoogle Scholar
• Glinoer D. What happens to the normal thyroid during pregnancy? Thyroid 1999;9:631–5
   PubMed Web of Science ®Google Scholar
• Alexander EK, Marqusee E, Lawrence J, et al. Timing and magnitude of increases in levothyroxine requirements during pregnancy in women with hypothyroidism. N Engl J Med 2004;351:241–9
   PubMed Web of Science ®Google Scholar
• Abalovich M, Alcaraz G, Kleiman-Rubinsztein J, et al. The relationship of preconception thyrotropin levels to requirements for increasing the levothyroxine dose during pregnancy in women with primary hypothyroidism. Thyroid 2010;20:1175–8
   PubMed Web of Science ®Google Scholar
• Verga U, Bergamaschi S, Cortelazzi D, et al. Adjustment of L-T4 substitutive therapy in pregnant women with subclinical, overt or post-ablative hypothyroidism. Clin Endocrinol (Oxf) 2009;70:798–802
   PubMed Web of Science ®Google Scholar
• Vita R, Fallahi P, Antonelli A, Benvenga S. The administration of L-thyroxine as soft gel capsule or liquid solution. Expert Opin Drug Deliv 2014;11:1103–11
   PubMed Web of Science ®Google Scholar
• Negro R, Valcavi R, Agrimi D, Toulis KA. Levothyroxine liquid solution versus tablet for replacement treatment in hypothyroid patients. Endocr Pract 2014;20:901–6
   PubMed Web of Science ®Google Scholar
• Cappelli C, Pirola I, Daffini L, et al. Thyroid hormonal profile in elderly patients treated with two different levothyroxine formulations: a single institute survey. Eur Geriatr Med 2014;5:382–5
   PubMed Web of Science ®Google Scholar
• Negro R, Stagnaro-Green A. Diagnosis and management of subclinical hypothyroidism in pregnancy. BMJ 2014;349:g4929
   PubMed Web of Science ®Google Scholar
• Stagnaro-Green A. Overt hyperthyroidism and hypothyroidism during pregnancy. Clin Obstet Gynecol 2011;54:478–87
   PubMed Web of Science ®Google Scholar
• Yassa L, Marqusee E, Fawcett R, Alexander EK. Thyroid hormone early adjustment in pregnancy (the THERAPY) trial. J Clin Endocrinol Metab 2010;95:3234–41
   PubMed Web of Science ®Google Scholar
• Mandel SJ, Larsen PR, Seely EW, Brent GA. Increased need for thyroxine during pregnancy in women with primary hypothyroidism. N Engl J Med 1990;323:91–6
   PubMed Web of Science ®Google Scholar
• Kothari A, Girling J. Hypothyroidism in pregnancy: pre-pregnancy thyroid status influences gestational thyroxine requirements. BJOG 2008;115:1704–8
   PubMed Web of Science ®Google Scholar
• Ianiro G, Mangiola F, Di Rienzo TA, et al. Levothyroxine absorption in health and disease, and new therapeutic perspectives. Eur Rev Med Pharmacol Sci 2014;18:451–6
   PubMed Web of Science ®Google Scholar
• Sachmechi I, Reich DM, Aninyei M, et al. Effect of proton pump inhibitors on serum thyroid-stimulating hormone level in euthyroid patients treated with levothyroxine for hypothyroidism. Endocr Pract 2007;13:345–9
   PubMedGoogle Scholar
• Centanni M, Gargano L, Canettieri G, et al. Thyroxine in goiter, Helicobacter pylori infection, and chronic gastritis. N Engl J Med 2006;354:1787–95
   PubMed Web of Science ®Google Scholar
• Costantine MM. Physiologic and pharmacokinetic changes in pregnancy. Front Pharmacol 2014;5:1–5
   PubMed Web of Science ®Google Scholar
• Dawes M, Chowienczyk PJ. Drugs in pregnancy. Pharmacokinetics in pregnancy. Best Pract Res Clin Obstet Gynaecol 2001;15:819–26
   PubMed Web of Science ®Google Scholar
• Cappell MS, Garcia A. Gastric and duodenal ulcers during pregnancy. Gastroenterol Clin North Am 1998;27:169–95
   PubMed Web of Science ®Google Scholar
• Parry E, Shields R, Turnbull AC. Transit time in the small intestine in pregnancy. J Obstet Gynaecol Br Commonw 1970;77:900–1
   PubMedGoogle Scholar
• Vita R, Saraceno G, Trimarchi F, Benvenga S. Switching levothyroxine from the tablet to the oral solution formulation corrects the impaired absorption of levothyroxine induced by proton-pump inhibitors. J Clin Endocrinol Metab 2014;99:4481–6
   PubMed Web of Science ®Google Scholar
• Santaguida MG, Virili C, Duca SC, et al. Thyroxine softgel capsule in patients with gastric-related T4 malabsorption. Endocrine 2015;49:51–7
   PubMed Web of Science ®Google Scholar
• Cappelli C, Pirola I, Gandossi E, et al. Oral liquid levothyroxine treatment at breakfast: a mistake? Eur J Endocrinol 2013;170:95–9
   PubMed Web of Science ®Google Scholar
• Pirola I, Daffini L, Gandossi E, et al. Comparison between liquid and tablet levothyroxine formulations in patients treated through enteral feeding tube. J Endocrinolol Invest 2014;37:583–7
   PubMed Web of Science ®Google Scholar
• Pirola I, Formenti AM, Gandossi E, et al. Oral liquid L-thyroxine (L-t4) may be better absorbed compared to L-T4 tablets following bariatric surgery. Obes Surg 2013;23:1493–6
   PubMed Web of Science ®Google Scholar
• Shawe J, Delbaere I, Ekstrand M, et al. Preconception care policy, guidelines, recommendations and services across six European countries: Belgium (Flanders), Denmark, Italy, the Netherlands, Sweden and the United Kingdom. Eur J Contracept Reprod Health Care 2015;20:77–87
   PubMed Web of Science ®Google Scholar
• Procter SB, Campbell CG. Position of the Academy of Nutrition and Dietetics: nutrition and lifestyle for a healthy pregnancy outcome. J Acad Nutr Diet 2014;114:1099–103
   PubMed Web of Science ®Google Scholar
• Patra J, Bakker R, Irving H, et al. Dose-response relationship between alcohol consumption before and during pregnancy and the risks of low birthweight, preterm birth and small for gestational age (SGA) – a systematic review and meta-analyses. BJOG 2011;118:1411–21
   PubMed Web of Science ®Google Scholar