Hyperglycemia in postmenopausal women screened for the metabolic syndrome is associated to increased sexual complaints

References

• Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third national health and nutrition examination survey. JAMA 2002;287:356–359.
   PubMed Web of Science ®Google Scholar
• Rosamond W, Flegal K, Friday G, Furie K, Go A, Greenlund K, Haase N, Ho M, Howard V, Kissela B, et al American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics – 2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2007;115:e69–e171.
   PubMed Web of Science ®Google Scholar
• Hidalgo LA, Chedraui PA, Morocho N, Alvarado M, Chavez D, Huc A. The metabolic syndrome among postmenopausal women in Ecuador. Gynecol Endocrinol 2006;22:447–454.
   PubMed Web of Science ®Google Scholar
• Janssen I, Powell LH, Crawford S, Lasley B, Sutton-Tyrrell K. Menopause and the metabolic syndrome: the study of women's health across the nation. Arch Intern Med 2008;168:1568–1575.
   PubMed Web of Science ®Google Scholar
• Cho GJ, Lee JH, Park HT, Shin JH, Hong SC, Kim T, Lee KW, Park YK, Kim SH. Postmenopausal status according to years since menopause as an independent risk factor for the metabolic syndrome. Menopause 2008;15:524–529.
   PubMed Web of Science ®Google Scholar
• Rossi R, Nuzzo A, Origliani G, Modena MG. Metabolic syndrome affects cardiovascular risk profile and response to treatment in hypertensive postmenopausal women. Hypertension 2008;52:865–872.
   PubMed Web of Science ®Google Scholar
• Llaneza P, Iñarrea J, Gonzalez C, Alonso A, Arnott I, Ferrer-Barriendos J. Differences in health related quality of life in a sample of Spanish menopausal women with and without obesity. Maturitas 2007;58:387–394.
   PubMed Web of Science ®Google Scholar
• Chedraui P, Hidalgo L, Chavez D, Morocho N, Alvarado M, Huc A. Quality of life among postmenopausal Ecuadorian women participating in a metabolic syndrome screening program. Maturitas 2007;56:45–53.
   PubMed Web of Science ®Google Scholar
• Chedraui P, Hidalgo L, Chavez D, Morocho N, Alvarado M, Huc A. Menopausal symptoms and associated risk factors among postmenopausal women screened for the metabolic syndrome. Arch Gynecol Obstet 2007;275:161–168.
   PubMedGoogle Scholar
• Laferrère B, Zhu S, Clarkson JR, Yoshioka MR, Krauskopf K, Thornton JC, Pi-Sunyer FX. Race, menopause, health-related quality of life, and psychological well-being in obese women. Obes Res 2002;10:1270–1275.
   PubMedGoogle Scholar
• Juliá-Mollá MD, García-Sánchez Y, Romeu Sarrió A, Pérez-López FR. Cimicifuga racemosa treatment and health related quality of life in postmenopausal Spanish women. Gynecol Endocrinol 2009;25:21–26.
   PubMed Web of Science ®Google Scholar
• Castelo-Branco C, Palacios S, Ferrer-Barriendos J, Cancelo MJ, Quereda F, Alberich X. The Cervantes study group. Impact of anthropometric parameters on quality of life during menopause. Fertil Steril, in press.
   Google Scholar
• Esposito K, Ciotola M, Marfella R, Di Tommaso D, Cobellis L, Giugliano D. The metabolic syndrome: a cause of sexual dysfunction in women. Int J Impot Res 2005;17:224–226.
   PubMed Web of Science ®Google Scholar
• Ponholzer A, Temml C, Rauchenwald M, Marszalek M, Madersbacher S. Is the metabolic syndrome a risk factor for female sexual dysfunction in sexually active women? Int J Impot Res 2008;20:100–104.
   PubMed Web of Science ®Google Scholar
• Esposito K, Ciotola M, Giugliano F, Bisogni C, Schisano B, Autorino R, Cobellis L, De Sio M, Colacurci N, Giugliano D. Association of body weight with sexual function in women. Int J Impot Res 2007;19:353–357.
   PubMed Web of Science ®Google Scholar
• Doumas M, Tsiodras S, Tsakiris A, Douma S, Chounta A, Papadopoulos A, Kanellakopoulou K, Giamarellou H. Female sexual dysfunction in essential hypertension: a common problem being uncovered. J Hypertens 2006;24:2387–2392.
   PubMed Web of Science ®Google Scholar
• McCall K, Meston C. Differences between pre- and postmenopausal women in cues for sexual desire. J Sex Med 2007;4:364–371.
   PubMed Web of Science ®Google Scholar
• Pastore LM, Carter RA, Hulka BS, Wells E. Self-reported urogenital symptoms in postmenopausal women: women's health initiative. Maturitas 2004;49:292–303.
   PubMed Web of Science ®Google Scholar
• Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP). JAMA 2001;285:2486–2497.
   PubMed Web of Science ®Google Scholar
• Hilditch JR, Lewis J, Peter A, van Maris B, Ross A, Franssen E, Guyatt GH, Norton PG, Dunn E. A menopause-specific quality of life questionnaire: development and psychometric properties. Maturitas 1996;24:161–175.
   PubMed Web of Science ®Google Scholar
• Blumel JE, Castelo-Branco C, Binfa L, Gramegna G, Tacla X, Aracena B, Cumsille MA, Sanjuan A. Quality of life after the menopause: a population study. Maturitas 2000;34:17–23.
   PubMed Web of Science ®Google Scholar
• Chedraui P, Pérez-López FR, San Miguel G, Avila C. Assessment of sexuality among middle aged women using the female sexual function index. Climacteric 2009;12:213–221.
   PubMed Web of Science ®Google Scholar
• Chedraui P, Morales B, Hidalgo L. Depression and related risk factors among climacteric women Climacteric 2008;11:125.
   Google Scholar
• Valadares AL, Pinto-Neto AM, Conde DM, Osis MJ, Sousa MH, Costa-Paiva L. The sexuality of middle-aged women with a sexual partner: a population-based study. Menopause 2008;15:706–713.
   PubMed Web of Science ®Google Scholar
• Dennerstein L. Sexuality, midlife, and menopause. Menopause 2008;15:221–222.
   PubMed Web of Science ®Google Scholar
• Pérez-López FR. The menopause. Madrid: Temas de Hoy; 1992.
   Google Scholar
• Davis SR, Moreau M, Kroll R, Bouchard C, Panay N, Gass M, Braunstein GD, Hirschberg AL, Rodenberg C, Pack S, et al APHRODITE Study Team. Testosterone for low libido in postmenopausal women not taking estrogen. N Engl J Med 2008;359:2005–2017.
   PubMed Web of Science ®Google Scholar
• Dennerstein L, Lehert P, Koochaki PE, Graziottin A, Leiblum S, Alexander JL. A symptomatic approach to understanding women's health experiences: a cross-cultural comparison of women aged 20 to 70 years. Menopause 2007;14:688–696.
   PubMed Web of Science ®Google Scholar
• Hayes RD, Dennerstein L, Bennett CM, Fairley CK. What is the ‘true’ prevalence of female sexual dysfunctions and does the way we assess these conditions have an impact? J Sex Med 2008;5:777–787.
   PubMed Web of Science ®Google Scholar
• Chedraui P, Aguirre W, Hidalgo L, Fayad L. Assessing menopausal symptoms among healthy middle aged women with the menopause rating scale. Maturitas 2007;57:271–278.
   PubMed Web of Science ®Google Scholar
• Laumann EO, Paik A, Rosen RC. Sexual dysfunction in the United States. Prevalence and predictors. JAMA 1999;281:537–544.
   PubMed Web of Science ®Google Scholar
• Heiman JR, Guess MK, Connell K, Melman A, Hyde JS, Segraves RT, Wyllie MG. Standards for clinical trials in sexual dysfunctions of women: research designs and outcomes assessment. J Sex Med 2004;1:92–97.
   PubMed Web of Science ®Google Scholar
• Khademi A, Alleyassin A, Amini M, Ghaemi M. Evaluation of sexual dysfunction prevalence in infertile couples. J Sex Med 2007;5:1402–1410.
   PubMed Web of Science ®Google Scholar
• Derogatis LR, Burnett AL. The epidemiology of sexual dysfunctions. J Sex Med 2008;5:289–300.
   PubMed Web of Science ®Google Scholar
• Dennerstein L, Guthrie JR, Hayes RD, DeRogatis LR, Lehert P. Sexual function, dysfunction, and sexual distress in a prospective, population-based sample of mid-aged, Australian-born women. J Sex Med 2008;5:2291–2299.
   PubMed Web of Science ®Google Scholar
• Zollner YF, Acquadro C, Schaefer M. Literature review of instruments to assess health-related quality of life during and after menopause. Qual Life Res 2005;14:309–327.
   PubMed Web of Science ®Google Scholar
• Palacios S, Ferrer-Barriendos J, Parrilla JJ, Castelo-Branco C, Manubens M, Alberich X, Marti A. Health-related quality of life in the Spanish women through and beyond menopause. Development and validation of the Cervantes Scale. Med Clin (Barc) 2004;122:205–211.
   PubMed Web of Science ®Google Scholar
• Blumel JE, Castelo-Branco C, Cancelo MJ, Romero H, Aprikian D, Sarra S. Impairment of sexual activity in middle-aged women in Chile. Menopause 2004;11:78–81.
   PubMed Web of Science ®Google Scholar
• Yánez D, Castelo-Branco C, Hidalgo LA, Chedraui PA. Sexual dysfunction and related risk factors in a cohort of middle-aged Ecuadorian women. J Obstet Gynaecol 2006;26:682–686.
   PubMedGoogle Scholar
• Blumel JE, Araya H, Riquelme R, Castro G, Sanchez F, Gramegna G. Prevalence of sexual dysfunction in climacteric women. Influence of menopause and hormone replace therapy. Rev Med Chil 2002;130:1131–1138.
   PubMed Web of Science ®Google Scholar
• Blümel JE, Leon-Leon P, Chedraui P, Baron G, Belzares E, Bencosme A, Calle A, Flores D, Espinoza MT, Izaguirre H, et al Sexual dysfunction in Latin America: prevalence and risk factors. Climacteric 2008;11:175.
   PubMed Web of Science ®Google Scholar
• Royer M, Castelo-Branco C, Blumel JE, Chedraui PA, Danckers L, Bencosme A, Navarro D, Vallejo S, Espinoza MT, Gomez G, et al The US National Cholesterol Education Programme Adult Treatment Panel III (NCEP ATP III): prevalence of the metabolic syndrome in postmenopausal Latin American women. Climacteric 2007;10:164–170.
   PubMed Web of Science ®Google Scholar
• Schreiner-Engel P, Schiavi RC, Vietorisz D, Smith H. The differential impact of diabetes type on female sexuality. J Psychosom Res 1987;31:23–33.
   PubMed Web of Science ®Google Scholar
• Newman AS, Bertelson AD. Sexual dysfunction in diabetic women. J Behav Med 1986;9:261–270.
   PubMed Web of Science ®Google Scholar
• Enzlin P, Mathieu C, Van Den Bruel A, Vanderschueren D, Demyttenaere K. Prevalence and predictors of sexual dysfunction in patients with type 1 diabetes. Diabetes Care 2003;26:409–414.
   PubMed Web of Science ®Google Scholar
• Mezones-Holguin E, Blümel JE, Huezo M, Vargas R, Castro J, Córdova W, Valenzuela G, Castelo-Branco C. Impact of diabetes mellitus on the sexuality of Peruvian postmenopausal. Gynecol Endocrinol 2008;24:470–474.
   PubMed Web of Science ®Google Scholar
• De Mattia G, Bravi MC, Laurenti O, Moretti A, Cipriani R, Gatti A, Mandosi E, Morano S. Endothelial dysfunction and oxidative stress in type 1 and type 2 diabetic patients without clinical macrovascular complications. Diabetes Res Clin Pract 2008;79:337–342.
   PubMed Web of Science ®Google Scholar
• Morano S. Pathophysiology of diabetic sexual dysfunction. J Endocrinol Invest 2003;26:65–69.
   PubMed Web of Science ®Google Scholar
• Musicki B, Burnett AL. Endothelial dysfunction in diabetic erectile dysfunction. Int J Impot Res 2007;19:129–138.
   PubMed Web of Science ®Google Scholar
• Torréns JI, Sutton-Tyrrell K, Zhao X, Matthews K, Brockwell S, Sowers M, Santoro N. Relative androgen excess during the menopausal transition predicts incident metabolic syndrome in midlife women: study of women's health across the nation. Menopause 2009;16:257–264.
   PubMed Web of Science ®Google Scholar
• Carr MC. The emergence of the metabolic syndrome with menopause. J Clin Endocrinol Metab 2003;88:2404–2411.
   PubMed Web of Science ®Google Scholar
• Weinberg ME, Manson JE, Buring JE, Cook NR, Seely EW, Ridker PM, Rexrode KM. Low sex hormone–binding globulin is associated with the metabolic syndrome in postmenopausal women. Metabolism 2006;55:1473–1480.
   PubMed Web of Science ®Google Scholar
• Maggio M, Lauretani F, Ceda GP, Bandinelli S, Basaria S, Paolisso G, Ble A, Egan JM, Metter EJ, Abbatecola AM, et al Association of hormonal dysregulation with metabolic syndrome in older women: data from the InCHIANTI study. Am J Physiol Endocrinol Metab 2007;292:E353–E358.
   PubMed Web of Science ®Google Scholar
• Akin F, Bastemir M, Alkış E, Kaptanoglu B. SHBG levels correlate with insulin resistance in postmenopausal women. Eur J Internal Med 2008;20:162–167.
   PubMed Web of Science ®Google Scholar
• Dennerstein L, Lehert P. Women's sexual functioning, lifestyle, mid-age, and menopause in 12 European countries. Menopause 2004;11:778–785.
   PubMed Web of Science ®Google Scholar
• Conroy RM, Pyörälä K, Fitzgerald AP, Sans S, Menotti A, De Backer G, De Bacquer D, Ducimetière P, Jousilahti P, Keil U, et al SCORE project group. Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. Eur Heart J 2003;24:987–1003.
   PubMed Web of Science ®Google Scholar