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Thyroid

Virilising Sertoli–Leydig cell tumour associated with thyroid papillary carcinoma: case report and general considerations

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Pages 617-622 | Received 01 Oct 2009, Accepted 20 Jan 2010, Published online: 16 Jul 2010

References

  • Meyer R. Pathology of some special ovarian tumors and their relation of sex characteristics. Am J Obstet Gynecol 1931;22:697.
  • Roth LM, Anderson MC, Govan AD, et al Sertoli–Leydig cell tumors: a clinicopathologic study of 34 cases. Cancer 1981;48:187.
  • Young RH, Scully RE. Ovarian Sertoli–Leydig cell tumors with a retiform pattern: a problem in histopathological diagnosis. A report of 25 cases. Am J Surg Pathol 1983;7:755.
  • Zaloudek C, Norris HJ. Sertoli–Leydig cell tumors of the ovary. A clinicopathologic study of 64 intermediate and poorly differentiated neoplasms. Am J Surg Pathol 1984;8:405.
  • Fleckenstein G, Sattler B, Hinney B, et al Androblastoma of the ovary: clinical, diagnostic and histopathologic features. Onkologie 2001;24:286–291.
  • Koonings PP, Campbell K, Mishell DR Jr, Grimes DA. Relative frequency of primary ovarian neoplasm: A 10-year review. Obstet Gynecol 1989;74:921.
  • Adam S. Levy, Director, Fellowship Training Program, Section of Pediatric Hematology/Oncology, The Children's Hospital at Montefiore, Bronx, NY. Review provided by VeriMed Healthcare Network, Arrhenoblastoma of ovary, Review Date: 5/22/2006.
  • Matzuk MM, Kumar R, Shou W, et al Transgenic models to study the roles of inhibin and activins in reproduction oncogenesis and development. Recent Prog Horm Res 1996;51:123–157.
  • Fletcher JA, Gibas Z, Donovan K, et al Ovarian granulosa-stromal cell tumors are characterized by trisomy 12. Am J Pathol 1991;138:515–520.
  • Villares Fragoso MC, Latronico AC, Marino Carvalho, et al Activating Mutation of the Stimulatory G Protein (gsp) as a putative cause of ovarian and testicular human Stromal Leydig cell tumors. J Clin Endocrinol Metab 1998;83:2074–2078.
  • Zhao C, Bratthauer G, Barner R, Vang R. Immunohistochemical analysis of Sox9 in ovarian Sertoli cell tumors and other tumors in the differential diagnosis. Int J Gynecol Pathol 2007;26:1–9.
  • Talerman A, Hughesdon PE, Anderson M. Diffuse nonlobular ovarian androblastoma usually associated with feminization. Int J Gynecol Pathol 1982;1:155–714.
  • Zung A, Shoham Z, Open M, et al Sertoli cell tumor causing precocious puberty in a girl with Peutz-Jeghers syndrome. Gynecol Oncol 1998;70:421–424.
  • Koh K, Fukuda Y. Androblastoma in a five-year-old girl. Jpn J Clin Oncol 1989;19:149–152.
  • Poonam S, Raksha A, Chandan D, et al Sertoli–Leydig cell tumor: a rare ovarian neoplasm. Case report and review of literature. Gynecol Endocrinol 2008;24:230–234.
  • Kasperlik-Zaluska AA, Sikorowa L, Ploch E, et al Ectopic ACTH syndrome due to bilateral ovarian androblastoma with double, gynandroblastic differentiation in one ovary. Eur J Obstet Gynecol Reprod Biol 1993;52:223–228.
  • Luton JP, Lesobre B, Valcke JC, et al Precocious pseudo-puberty due to HCG-secreting androblastoma of the ovary. One case. Nouv Presse Med 1980;9:2539–2544.
  • Ehrlich EN, Dominguez OV, Samuels LT, et al Aldosteronism and precocious puberty due to an ovarian androblastoma (Sertoli cell tumor). J Clin Endocrinol Metab 1963;23:358.
  • Young RH, Scully RE. Ovarian Sertoli–Leydig cell tumors. A clinicopathological analysis of 207 cases. Am J Surg Pathol 1985;9:543–569.
  • Oliva E, Alvarez T, Young RH. Sertoli cell tumors of the ovary: a clinicopathologic and immunohistochemical study of 54 cases. Am J Surg Pathol 2005;29:143–156.
  • Sanz OA, Rubio Matinez P, Troyas Guarch R, et al Bilateral Leydig cell tumor of the ovary: a rare cause of virilization in postmenopausal patient. Maturitas 2007;57:214–216.
  • Roth LM. Recent advances in the pathology and classification of ovarian sex cord-stromal tumors. Int J Gynecol Pathol 2006;25:199–215.
  • Zhao C, Vinh T, McManus K, et al Identification of the most sensitive and robust immunohistochemical markers in different categories of ovarian sex cord-stromal tumors. Am J Surg Pathol 2009;33:354–366.
  • Movahedi-Lankarani S, Kurman RJ. Calretinin, a more sensitive but less specific marker than alpha-inhibin for ovarian sex cord-stromal neoplasms: an immunohistochemical study of 215 cases. Am J Surg Pathol 2002;26:1477–1483.
  • Santoro M, Carlomagno F, Hay ID, et al RET oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype. J Clin Invest 1992;89:1517–1522.
  • Kimura ET, Nikiforova MN, Zhu Z, et al High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma. Cancer Res 2003;63:1454–1457.
  • Jensen RD, Norris HJ, Fraumeni JF Jr. Familial arrhenoblastoma and thyroid adenoma. Cancer 1974;33:218–223.
  • O'Brien PK, Wilansky DL. Familial thyroid nodulation and arrhenoblastoma. Am J Clin Pathol 1981;75:578–581.
  • Harach HR, Williams GT, Williams ED. Familial adenomatous polyposis associated thyroid carcinoma: a distinct type of follicular cell neoplasm. Histopathology1994;25:549–561.

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