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Gynecological Endocrinology Volume 10, 1996 - Issue sup2
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Original Article

Factor V Leiden mutation and contraception

F. M. Helnierhrst Department of Obstetrics, Gynecology and Reproductive Medlcine, University Hospital Leiden
,
K. W. M. Bloemenkanip Department of Obstetrics, Gynecology and Reproductive Medlcine, University Hospital Leiden
,
E. Briët Department of Internal Medcine, University Hospital Leiden
,
F. J.M. Van der Meer Department of Obstetrics, Gynecology and Reproductive Medlcine, University Hospital Leiden
,
F. R. Rosendaal Department of Internal Medcine, University Hospital Leiden; Department of Clinical Epidemiology, University Hospital Leiden, The Netherlands
&
J. P. Vandenbroircke Department of Clinical Epidemiology, University Hospital Leiden, The Netherlands
Pages 85-87 | Published online: 07 Jul 2009

References

  • Koster T., Small R. A., Rosendaal F. R., Helmerhorst F. M. Oral contraceptives and venous thromboembolism: a quantitative discussion of the uncertainties. J. Int. Men. 1995; 238: 31–7
  • Farmer R. D.T., Preston T. D. The risk of venous thromboembolism associated with low oestrogen oral contraceptives. J. Obstet. Gynecol. 1995; 15: 195–200
  • Vandenbroucke J. P., Koster T., Briët E., Reitsma P. H., Bertina R. M., Rosendaal F. R. Increased risk of venous thrombosis in oral-contraceptive users who are carriers of Factor V Leiden mutation. Lancet 1994; 334: 1453–7
  • Vademecum of Health Statistics of The Netherlands. Netherlands Central Bureau of Statistics. Ministry of Welfare, Health and Cultural Mairs, Voorburg 1994, 1994
  • Stadel B. V. Oral contraceptives and cardiovascular disease. N. Engl. J. Med. 1981; 305: 612-–18; 672–7
  • Anderson F. A., Wheeler H. B., Goldberg R. J., Hosmer D. W., Patwardhan A., Jovanovic B., Forrier A., Dalen J. E. A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. Arch. Intern. Med. 1991; 151: 933–8
  • Pasi K. J., Perry D. J., Lee C. A. Thromboembolism and the combined oral contraceptive pill. Lancet 1995; 345: 1437
  • Rees C. R., Cox M., Clegg J. B. World distribution of factor V Leiden. Lancet 1995; 346: 1133–4
  • Early diagnosis. Clinical Epidemiology, 2nd edition, D. L. Sackett, R. B. Haynes, G. H. Guyatt, P. Tagwell. Little Brown and Company, Boston, Toronto, London 1991
  • Rosendaal F. R., Koster T., Vandenbroucke J. P., Reitsma P. H. High risk of thrombosis in patients homozygous for factor V Leiden (Activated Protein C Resistance). Blood 1995; 85: 1504–8

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