Ca²⁺ leakage rate from agonist-sensitive intracellular pools is altered in platelets from patients with type 2 diabetes

References

• Lopaschuk GD, Ussher JR, Folmes CD, Jaswal JS, Stanley WC. Myocardial fatty acid metabolism in health and disease. Physiol Rev 2010; 90: 207–258
   PubMed Web of Science ®Google Scholar
• Cooksey RC, Jouihan HA, Ajioka RS, Hazel MW, Jones DL, Kushner JP, McClain DA. Oxidative stress, beta-cell apoptosis, and decreased insulin secretory capacity in mouse models of hemochromatosis. Endocrinology 2004; 145: 5305–5312
   PubMed Web of Science ®Google Scholar
• Chao CY, Cheing GL. Microvascular dysfunction in diabetic foot disease and ulceration. Diabetes Metab Res Rev 2009; 25: 604–614
   PubMedGoogle Scholar
• Natarajan A, Zaman AG, Marshall SM. Platelet hyperactivity in type 2 diabetes: Role of antiplatelet agents. Diab Vasc Dis Res 2008; 5: 138–144
   PubMed Web of Science ®Google Scholar
• Sobol AB, Watala C. The role of platelets in diabetes-related vascular complications. Diabetes Res Clin Pract 2000; 50: 1–16
   PubMedGoogle Scholar
• Rosado JA, Saavedra FR, Redondo PC, Hernandez-Cruz JM, Salido GM, Pariente JA. Reduced plasma membrane Ca2+-ATPase function in platelets from patients with non-insulin-dependent diabetes mellitus. Haematologica 2004; 89: 1142–1144
   PubMedGoogle Scholar
• Zbidi H, Lopez JJ, Amor NB, Bartegi A, Salido GM, Rosado JA. Enhanced expression of STIM1/Orai1 and TRPC3 in platelets from patients with type 2 diabetes mellitus. Blood Cells Mol Dis 2009; 43: 211–213
   PubMedGoogle Scholar
• Saavedra FR, Redondo PC, Hernandez-Cruz JM, Salido GM, Pariente JA, Rosado JA. Store-operated Ca2+ entry and tyrosine kinase pp60src hyperactivity are modulated by hyperglycemia in platelets from patients with non insulin-dependent diabetes mellitus. Arch Biochem Biophys 2004; 432: 261–268
   PubMedGoogle Scholar
• Bobe R, Bredoux R, Corvazier E, Andersen JP, Clausen JD, Dode LKovács T, Enouf J. Identification, expression, function, and localization of a novel (sixth) isoform of the human sarco/endoplasmic reticulum Ca2+ATPase 3 gene. J Biol Chem 2004; 279: 24297–24306
   PubMed Web of Science ®Google Scholar
• Cavallini L, Coassin M, Alexandre A. Two classes of agonist-sensitive Ca2+ stores in platelets, as identified by their differential sensitivity to 2,5-di-(tert-butyl)-1,4-benzohydroquinone and thapsigargin. Biochem J 1995; 310(Pt 2)449–452
   PubMedGoogle Scholar
• Lopez JJ, Camello-Almaraz C, Pariente JA, Salido GM, Rosado JA. Ca2+ accumulation into acidic organelles mediated by Ca2+- and vacuolar H+-ATPases in human platelets. Biochem J 2005; 390: 243–252
   PubMedGoogle Scholar
• Lopez JJ, Redondo PC, Salido GM, Pariente JA, Rosado JA. Two distinct Ca2+ compartments show differential sensitivity to thrombin, ADP and vasopressin in human platelets. Cell Signal 2006; 18: 373–381
   Google Scholar
• Rosado JA, Lopez JJ, Gomez-Arteta E, Redondo PC, Salido GM, Pariente JA. Early caspase-3 activation independent of apoptosis is required for cellular function. J Cell Physiol 2006; 209: 142–152
   PubMedGoogle Scholar
• Toescu EC, Petersen OH. Region-specific activity of the plasma membrane Ca2+ pump and delayed activation of Ca2+ entry characterize the polarized, agonist-evoked Ca2+ signals in exocrine cells. J Biol Chem 1995; 270: 8528–8535
   PubMedGoogle Scholar
• Rosado JA, Sage SO. Regulation of plasma membrane Ca2+-ATPase by small GTPases and phosphoinositides in human platelets. J Biol Chem 2000; 275: 19529–19535
   PubMed Web of Science ®Google Scholar
• Grynkiewicz G, Poenie M, Tsien RY. A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem 1985; 260: 3440–3450
   PubMed Web of Science ®Google Scholar
• Woodard GE, Lopez JJ, Jardin I, Salido GM, Rosado JA. TRPC3 regulates agonist-stimulated Ca2+ mobilization by mediating the interaction between type I inositol 1,4,5-trisphosphate receptor, RACK1, and Orai1. J Biol Chem 2010; 285: 8045–8053
   PubMedGoogle Scholar
• Rosado JA, Sage SO. Farnesylcysteine analogues inhibit store-regulated Ca2+ entry in human platelets: Evidence for involvement of small GTP-binding proteins and actin cytoskeleton. Biochem J 2000; 347(Pt 1)183–192
   PubMedGoogle Scholar
• Thastrup O, Foder B, Scharff O. The calcium mobilizing tumor promoting agent, thapsigargin elevates the platelet cytoplasmic free calcium concentration to a higher steady state level. A possible mechanism of action for the tumor promotion. Biochem Biophys Res Commun 1987; 142: 654–660
   PubMedGoogle Scholar
• Bose R, Li Y, Woo V. Sodium-calcium exchange in platelets of diabetics. Proc West Pharmacol Soc 2001; 44: 183–184
   PubMedGoogle Scholar
• Toescu EC, Petersen OH. The thapsigargin-evoked increase in [Ca2+]i involves an InsP3-dependent Ca2+ release process in pancreatic acinar cells. Pflugers Arch 1994; 427: 325–331
   PubMed Web of Science ®Google Scholar
• Berridge MJ, Bootman MD, Roderick HL. Calcium signalling: dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol 2003; 4: 517–529
   PubMed Web of Science ®Google Scholar
• Papp B, Enyedi A, Pászty K, Kovács T, Sarkadi B, Gárdos G, Magnier C, Wuytack F, Enouf J. Simultaneous presence of two distinct endoplasmic-reticulum-type calcium-pump isoforms in human cells. Characterization by radio-immunoblotting and inhibition by 2,5-di-(t-butyl)-1,4-benzohydroquinone. Biochem J 1992; 288(Pt 1)297–302
   PubMedGoogle Scholar
• Bobe R, Bredoux R, Wuytack F, Quarck R, Kovàcs T, Papp B, Corvazier E, Magnier C, Enouf J. The rat platelet 97-kDa Ca2+ATPase isoform is the sarcoendoplasmic reticulum Ca2+ATPase 3 protein. J Biol Chem 1994; 269: 1417–1424
   PubMed Web of Science ®Google Scholar
• Wuytack F, Papp B, Verboomen H, Raeymaekers L, Dode L, Bobe R, Enouf J, Bokkala S, Authi KS, Casteels R. A sarco/endoplasmic reticulum Ca2+-ATPase 3-type Ca2+ pump is expressed in platelets, in lymphoid cells, and in mast cells. J Biol Chem 1994; 269: 1410–1416
   PubMed Web of Science ®Google Scholar
• Harper AG, Mason MJ, Sage SO. A key role for dense granule secretion in potentiation of the Ca2+ signal arising from store-operated calcium entry in human platelets. Cell Calcium 2009; 45: 413–420
   PubMed Web of Science ®Google Scholar
• Van Coppenolle F, Vanden Abeele F, Slomianny C, Flourakis M, Hesketh J, Dewailly E, Prevarskaya N. Ribosome-translocon complex mediates calcium leakage from endoplasmic reticulum stores. J Cell Sci 2004; 117: 4135–4142
   PubMed Web of Science ®Google Scholar
• Alexandru N, Jardín I, Popov D, Simionescu M, García-Estañ J, Salido GM, Rosado JA. Effect of homocysteine on calcium mobilization and platelet function in type 2 diabetes mellitus. J Cell Mol Med 2008; 12: 2015–2026
   PubMed Web of Science ®Google Scholar
• Li Y, Woo V, Bose R. Platelet hyperactivity and abnormal Ca2+ homeostasis in diabetes mellitus. Am J Physiol Heart Circ Physiol 2001; 280: H1480–1489
   Web of Science ®Google Scholar
• Redondo PC, Jardin I, Hernandez-Cruz JM, Pariente JA, Salido GM, Rosado JA. Hydrogen peroxide and peroxynitrite enhance Ca2+ mobilization and aggregation in platelets from type 2 diabetic patients. Biochem Biophys Res Commun 2005; 333: 794–802
   PubMed Web of Science ®Google Scholar
• Zbidi H, Lopez JJ, Amor NB, Bartegi A, Salido GM, Rosado JA. Enhanced expression of STIM1/Orai1 and TRPC3 in platelets from patients with type 2 diabetes mellitus. Blood Cells Mol Dis 2009; 43: 211–213
   PubMedGoogle Scholar
• Chaabane C, Dally S, Corvazier E, Bredoux R, Bobe R, Ftouhi B, Raies A, Enouf J. Platelet PMCA- and SERCA-type Ca2+ -ATPase expression in diabetes: A novel signature of abnormal megakaryocytopoiesis. J Thromb Haemost 2007; 5: 2127–2135
   PubMed Web of Science ®Google Scholar
• Lopez JJ, Jardin I, Bobe R, Pariente JA, Enouf J, Salido GM, Rosado JA. STIM1 regulates acidic Ca2+ store refilling by interaction with SERCA3 in human platelets. Biochem Pharmacol 2008; 75: 2157–2164
   PubMedGoogle Scholar
• Randriamboavonjy V, Pistrosch F, Bölck B, Schwinger RH, Dixit M, Badenhoop K, Cohen RA, Busse R, Fleming I. Platelet sarcoplasmic endoplasmic reticulum Ca2+-ATPase and mu-calpain activity are altered in type 2 diabetes mellitus and restored by rosiglitazone. Circulation 2008; 117: 52–60
   PubMed Web of Science ®Google Scholar
• Setty BN, Werner MH, Hannun YA, Stuart MJ. 15-Hydroxyeicosatetraenoic acid-mediated potentiation of thrombin-induced platelet functions occurs via enhanced production of phosphoinositide-derived second messengers–sn-1,2-diacylglycerol and inositol-1,4,5-trisphosphate. Blood 1992; 80: 2765–2773
   PubMedGoogle Scholar
• Jardin I, Ben Amor N, Bartegi A, Pariente JA, Salido GM, Rosado JA. Differential involvement of thrombin receptors in Ca2+ release from two different intracellular stores in human platelets. Biochem J 2007; 401: 167–174
   PubMedGoogle Scholar
• Papp B, Enyedi A, Kovács T, Sarkadi B, Wuytack F, Thastrup O, Gárdos G, Bredoux R, Levy-Toledano S, Enouf J. Demonstration of two forms of calcium pumps by thapsigargin inhibition and radioimmunoblotting in platelet membrane vesicles. J Biol Chem 1991; 266: 14593–14596
   PubMed Web of Science ®Google Scholar
• Rosado JA, López JJ, Harper AG, Harper MT, Redondo PC, Pariente JA, Sage SO, Salido GM. Two pathways for store-mediated calcium entry differentially dependent on the actin cytoskeleton in human platelets. J Biol Chem 2004; 279: 29231–29235
   PubMed Web of Science ®Google Scholar
• Kovàcs T, Berger G, Corvazier E, Pàszty K, Brown A, Bobe R, Papp B, Wuytack F, Cramer EM, Enouf J. Immunolocalization of the multi-sarco/endoplasmic reticulum Ca2+ ATPase system in human platelets. Br J Haematol 1997; 97: 192–203
   PubMedGoogle Scholar
• Flourakis M, Van Coppenolle F, Lehen'kyi V, Beck B, Skryma R, Prevarskaya N. Passive calcium leak via translocon is a first step for iPLA2-pathway regulated store operated channels activation. FASEB J 2006; 20: 1215–1217
   PubMed Web of Science ®Google Scholar
• Pampolina C, McNicol A. Anisomycin does not activate p38MAPK in human platelets. Thromb Res 1999; 96: 27–35
   PubMedGoogle Scholar
• Ferreira IA, Mocking AI, Feijge MA, Gorter G, van Haeften TW, Heemskerk JW, Akkerman JW. Platelet inhibition by insulin is absent in type 2 diabetes mellitus. Arterioscler Thromb Vasc Biol 2006; 26: 417–422
   PubMed Web of Science ®Google Scholar