151
Views
7
CrossRef citations to date
0
Altmetric
Research Article

Lactate is a possible mediator of the glucose effect on platelet inhibition

, &
Pages 239-245 | Received 15 Dec 2012, Accepted 14 Jun 2013, Published online: 02 Aug 2013

References

  • Ferreiro JL, Gómez-Hospital JA, Angiolillo DJ. Platelet abnormalities in diabetes mellitus. Diab Vasc Dis Res 2010;7:251–259
  • Alexandru N, Popov D, Georgescu A. Platelet dysfunction in vascular pathologies and how can it be treated. Thromb Res 2012;129:116–126
  • Winocour PD, Watala C, Perry DW, Kinlough-Rathbone RL. Decreased platelet membrane fluidity due to glycation or acetylation of membrane proteins. Thromb Haemost 1992;68:577–582
  • Watala C, Golański J, Boncler MA, Pietrucha T, Gwoździński K. Membrane lipid fluidity of blood platelets: A common denominator that underlies the opposing actions of various agents that affect platelet activation in whole blood. Platelets 1998;9:315–327
  • Assert R, Scherk G, Bumbure A, Pirags V, Schatz H, Pfeiffer AF. Regulation of protein kinase C by short-term hyperglycaemia in human platelets in vivo and in vitro. Diabetologia 2001;44:188–195
  • Keating FK, Sobel BE, Schneider DJ. Effects of increased concentrations of glucose on platelet reactivity in healthy subjects and in patients with and without diabetes mellitus. Am J Cardiol 2003;92:1362–1365
  • Sudic D, Razmara M, Forslund M, Ji Q, Hjemdahl P, Li N. High glucose levels enhance platelet activation: Involvement of multiple mechanisms. Br J Haematol 2006;133:315–322
  • Tang WH, Stitham J, Gleim S, Di Febbo C, Porreca E, Fava C, Tacconelli S, Capone M, Evangelista V, Levantesi G, et al. Glucose and collagen regulate human platelet activity through aldose reductase induction of thromboxane. J Clin Invest 2011;121:4462–4476
  • Schwarz UR, Walter U, Eigenthaler M. Taming platelets with cyclic nucleotides. Biochem Pharmacol 2001;62:1153–1161
  • Massucco P, Mattiello L, Russo I, Traversa M, Doronzo G, Anfossi G, Trovati M. High glucose rapidly activates the nitric oxide/cyclic nucleotide pathway in human platelets via an osmotic mechanism. Thromb Haemost 2005;93:517–526
  • De La Cruz JP, Arrebola MM, Villalobos MA, Pinacho A, Guerrero A, González-Correa JA, Sánchez de la Cuesta F. Influence of glucose concentration on the effects of aspirin, ticlopidine and clopidogrel on platelet function and platelet-subendothelium interaction. Eur J Pharmacol 2004;484:19–27
  • Le Guyader A, Pacheco G, Seaver N, Davis-Gorman G, Copeland J, McDonagh PF. Inhibition of platelet GPIIb-IIIa and P-selectin expression by aspirin is impaired by stress hyperglycemia. J Diabetes Complications 2009;23:65–70
  • Kobzar G, Mardla V, Samel N. Short-term exposure of platelets to glucose impairs inhibition of platelet aggregation by cyclooxygenase inhibitors. Platelets 2011;22:338–344
  • Chen L, Salafranca MN, Mehta JL. Cyclooxygenase inhibition decreases nitric oxide synthase activity in human platelets. Am J Physiol 1997;273:H1854–H1859
  • O'Kane PD, Queen LR, Ji Y, Reebye V, Stratton P, Jackson G, Ferro A. Aspirin modifies nitric oxide synthase activity in platelets: Effects of acute versus chronic aspirin treatment. Cardiovasc Res 2003;59:152–159
  • O'Kane P, Xie L, Liu Z, Queen L, Jackson G, Ji Y, Ferro A. Aspirin acetylates nitric oxide synthase type 3 in platelets thereby increasing its activity. Cardiovasc Res 2009;83:123–130
  • Chakraborty K, Khan GA, Banerjee P, Ray U, Sinha AK. Inhibition of human blood platelet aggregation and the stimulation of nitric oxide synthesis by aspirin. Platelets 2003;14:421–427
  • Ferreira IA, Mocking AI, Urbanus RT, Varlack S, Wnuk M, Akkerman JW. Glucose uptake via glucose transporter 3 by human platelets is regulated by protein kinase B. J Biol Chem 2005;280:32625–32633
  • Naito E, Kuroda Y, Toshima K, Takeda E, Saijo T, Kobashi H, Yokota I, Ito M. Effect of sodium dichloroacetate on human pyruvate metabolism. Brain Dev 1989;11:195–197
  • Freedman JE, Farhat JH, Loscalzo J, Keaney JF Jr. Alpha-tocopherol inhibits aggregation of human platelets by a protein kinase C-dependent mechanism. Circulation 1996;94:2434–2440
  • Freedman JE, Li L, Sauter R, Keaney JF Jr. Alpha-tocopherol and protein kinase C inhibition enhance platelet-derived nitric oxide release. FASEB J 2000;14:2377–2379
  • Li D, Saldeen T, Romeo F, Mehta JL. Different isoforms of tocopherols enhance nitric oxide synthase phosphorylation and inhibit human platelet aggregation and peroxidation: Implications in therapy with vitamin E. J Cardiovasc Pharmacol Ther 2001;6:155–161
  • Anfossi G, Russo I, Massucco P, Mattiello L, Cavalot F, Balbo A, Trovati M. Adenosine increases human platelet levels of cGMP through nitric oxide: Possible role in its antiaggregating effect. Thromb Res 2002;105:71–78
  • Russo I, Doronzo G, Mattiello L, De Salve A, Trovati M, Anfossi G. The activity of constitutive nitric oxide synthase is increased by the pathway cAMP/cAMP-activated protein kinase in human platelets. New insights into the antiaggregating effects of cAMP-elevating agents. Thromb Res 2004;114:265–273
  • Anfossi G, Russo I, Massucco P, Mattiello L, Perna P, Tassone F, Trovati M. l-arginine modulates aggregation and intracellular cyclic 3,5-guanosine monophosphate levels in human platelets: Direct effect and interplay with antioxidative thiol agent. Thromb Res 1999;94:307–316
  • Coleman RA, Smith WL, Narumiya S. International Union of Pharmacology classification of prostanoid receptors: Properties, distribution, and structure of the receptors and their subtypes. Pharmacol Rev 1994;46:205–229
  • Radomski MW, Palmer RM, Moncada S. An l-arginine/nitric oxide pathway present in human platelets regulates aggregation. Proc Natl Acad Sci USA 1990;87:5193–5197
  • Radomski MW, Palmer RM, Moncada S. Characterization of the L-arginine:nitric oxide pathway in human platelets. Br J Pharmacol 1990;101:325–328
  • Anfossi G, Russo I, Massucco P, Mattiello L, Cavalot F, Balbo A, Trovati M. Adenosine increases human platelet levels of cGMP through nitric oxide: Possible role in its antiaggregating effect. Thromb Res 2002;105:71–78
  • Li D, Saldeen T, Romeo F, Mehta JL. Different isoforms of tocopherols enhance nitric oxide synthase phosphorylation and inhibit human platelet aggregation and peroxidation: Implications in therapy with vitamin E. J Cardiovasc Pharmacol Ther 2001;6:155–161
  • Gkaliagkousi E, Ritter J, Ferro A. Platelet-derived nitric oxide signaling and regulation. Circ Res 2007;101:654–662
  • Priora R, Margaritis A, Frosali S, Coppo L, Summa D, Di Giuseppe D, Aldinucci C, Pessina G, Di Stefano A, Di Simplicio P. In vitro inhibition of human and rat platelets by NO donors, nitrosoglutathione, sodium nitroprusside and SIN-1, through activation of cGMP-independent pathways. Pharmacol Res 2011;64:289–297
  • Davis KL, Martin E, Turko IV, Murad F. Novel effects of nitric oxide. Annu Rev Pharmacol Toxicol 2001;41:203–236
  • Boulos C, Jiang H, Balazy M. Diffusion of peroxynitrite into the human platelet inhibits cyclooxygenase via nitration of tyrosine residues. J Pharmacol Exp Ther 2000;293:222–229

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.