Helicobacter pylori infection & immune thrombocytopenic purpura in children and adolescents: A randomized controlled trial

References

• George JN, Woolf SH, Raskob GE, Wasser JS, Aledort LM, Ballem PJ, Blanchette VS, Bussel JB, Cines DB, Kelton JG, et al. Idiopathic thrombocytopenic purpura: A practice guideline developed by explicit methods for the American Society of Hematology. Blood 1996;88:3–40
   PubMed Web of Science ®Google Scholar
• Neunert C, Lim W, Crowther M, Cohen A, Solberg Jr L, Crowther MA. The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia. Blood 2011;117:4190–4207
   PubMed Web of Science ®Google Scholar
• Gasbarrini A, Franceschi F, Tartaglione R, Landolfi R, Pola P, Gasbarrini G. Regression of autoimmune thrombocytopenia after eradication of Helicobacter pylori. Lancet 1998;352:878
   PubMed Web of Science ®Google Scholar
• Stasi R, Sarpatwati A, Segal JB, Osborn J, Evangelista ML, Cooper N, Provan D, Newland A, Amadori S, Bussel JB. Effects of eradication of Helicobacter pylori infection in patients with immune thrombocytopenic purpura: A systematic review. Blood 2009;113:1231–1240
   PubMed Web of Science ®Google Scholar
• Satake M, Nishikawa J, Fukagawa Y, Akashi K, Okamoto T, Yoshida T, Hirano A, Maetani N, Iida Y, Sakaida I. The long-term efficacy of Helicobacter pylori eradication therapy in patients with idiopathic thrombocytopenic purpura. J Gastroenterol Hepatol 2007;22:2233–2237
   PubMedGoogle Scholar
• Tsumoto C, Tominaga K, Okazaki H, Tanigawa T, Yamagami H, Watanabe K, Nakao T, Koh K, Watanabe T, Fujawara Y, et al. Long-term efficacy of Helicobacter pylori eradication in patients with idiopathic thrombocytopenic purpura: 7-year follow-up prospective study. Ann Hematol 2009;88:789–793
   PubMed Web of Science ®Google Scholar
• Kikuchi T, Kobayashi T, Yamashita T, Ohashi K, Sakamaki H, Akiyama H. Eight-year follow-up of patients with immune thrombocytopenic purpura related to H. pylori infection. Platelets 2011;22:59–62
   Web of Science ®Google Scholar
• Jaing TH, Yang CP, Hung IJ, Chiu CH, Chang KW. Efficacy of Helicobacter pylori eradication on platelet recovery in children with chronic idiopathic thrombocytopenic purpura. Acta Paediatr 2003;92:1153–1157
   PubMed Web of Science ®Google Scholar
• Rajantie J, Klemola T. Helicobacter pylori and idiopathic thrombocytopenic purpura in children. Blood 2003;101:1660
   PubMed Web of Science ®Google Scholar
• Yetgin S, Demir H, Arslan D, Ünal S, Koçak N. Autoimmune thrombocytopenic purpura and Helicobacter pylori infection effectivity during childhood. Am J Hematol 2005;78:318
   PubMedGoogle Scholar
• Hayashi H, Okuda M, Aoyagi N, Yoshiyama M, Miyashiro E, Kounami S, Yashikawa N. Helicobacter pylori infection in children with chronic idiopathic thrombocytopenic purpura. Pediatr Int 2005;47:292–295
   PubMed Web of Science ®Google Scholar
• Neefjes VME, Heijboer H, Tamminga RYJ. H. pylori infection in childhood chronic immune thrombocytopenic purpura. Haematologica 2007;92:576
   PubMedGoogle Scholar
• Loffredo G, Marzano MG, Migliorati R, Miele E, Menna F, Poggi V, Staiano A. The relationship between immune thrombocytopenic purpura and Helicobacter pylori infection in children: Where is the truth? Eur J Pediatr 2007;166:1067–1068
   PubMedGoogle Scholar
• Bisogno G, Errigo G, Rosetti F, Sainati L, Pusiol A, DaDalt L, Colleselli P, Grotto P, Carli M. The role of Helicobacter pylori in children with chronic idiopathic thrombocytopenic purpura. J Pediatr Hematol Oncol 2008;30:53–57
   PubMed Web of Science ®Google Scholar
• Hamidieh AA, Arzanian MT, Gachkar L, Pasha F. Helicobacter pylori infection in children with chronic idiopathic thrombocytopenic purpura. J Pediatr Hematol Oncol 2008;30:96–97
   PubMedGoogle Scholar
• Veres G, Karóczkai I, Bodánszki H, Marosi A, Magyarossi E, Dezsófi A, Arató A. The role of Helicobacter pylori infection in children with chronic immune thrombocytopenic purpura. Orv Hetil 2009;150:801–804
   PubMedGoogle Scholar
• Ferrara M, Capozzi L, Russo R. Effect of Helicobacter pylori eradication on PLT count in children with chronic idiopathic thrombocytopenic purpura. Hematology 2009;14:282–285
   PubMed Web of Science ®Google Scholar
• Treepongkaruna S, Sirachainan N, Kanjanapongkul S, Winaichatsak A, Sirithorn S, Sumritsopak R, Chuansumrit A. Absence of PLT recovery following Helicobacter pylori eradication in childhood chronic idiopathic thrombocytopenic purpura: A multi-center randomized controlled trial. Pediatr Blood Cancer 2009;53:72–77
   PubMedGoogle Scholar
• Russo G, Miraglia V, Branciforte F, Matarese SMR, Zecca M, Bisogno G, Parodi E, Amendola G, Giordano P, Jankovic M, et al. Effect of erradication of Helicobacter pylori in children with chronic immune thrombocytopenia: A prospective, controlled, multicenter study. Pediatr Blood Cancer 2011;56:273–278
   PubMed Web of Science ®Google Scholar
• Kawakami E, Machado RS, Reber M, Patrício FR. 13C-urea breath test with infrared spectroscopy for diagnosing Helicobacter pylori infection in children and adolescents. J Pediatr Gastroenterol Nutr 2002;35:39–43
   PubMedGoogle Scholar
• Raguza D, Machado RS, Ogata SK, Granato CF, Patrício FR, Kawakami E. Validation of a monoclonal stool antigen test for diagnosing Helicobacter pylori infection in young children. J Pediatr Gastroenterol Nutr 2010;50:400–403
   PubMed Web of Science ®Google Scholar
• Suzuki T, Matsushima M, Masui A, Watanabe K, Takagi A, Ogawa Y, Shirai T, Mine T. Effect of Helicobacter pylori eradication in patients with chronic idiopathic thrombocytopenic purpura – A randomized controlled trial. Am J Gastroenterol 2005;100:1265–1270
   PubMed Web of Science ®Google Scholar
• Kawakami E, Machado RS, Ogata SK, Langner M. Decrease in prevalence of Helicobacter pylori infection during a 10-year period in Brazilian children. Arq Gastroenterol 2008;45:147–151
   PubMedGoogle Scholar
• Miranda AC, Machado RS, Kawakami E. Spontaneous elimination of Helicobacter pylori infection in a cohort of asymptomatic school children by enzyme-linked immunosorbent assay polyclonal antigen in stool. J Clin Gastroenterol 2008;42:143–146
   PubMedGoogle Scholar
• Doğan Z, Filik L, Ergül B, Sarikaya M, Akbal E. Association between Helicobacter pylori and liver-to-spleen ratio: A randomized-controlled single-blind study. Eur J Gastroenterol Hepatol 2013;25:107–110
   PubMed Web of Science ®Google Scholar
• Cines DB, Blanchette VS. Immune thrombocytopenic purpura. N Engl J Med 2002;346:995–1008
   PubMed Web of Science ®Google Scholar
• Blanchette VS, Carcao M. Childhood acute immune thrombocytopenic purpura: 20 years later. Semin Thromb Hemost 2003;29:605–617
   PubMed Web of Science ®Google Scholar
• Imbach P, Kühne T, Müller D, Berchtold W, Zimmerman S, Elalfy M, Buchanan GR. Childhood ITP: 12 months follow-up data from the prospective Registry I if the Intercontinental Childhood ITP Study Group (ICIS). Pediatr Blood Cancer 2006;46:351–356
   PubMed Web of Science ®Google Scholar
• Takahashi T, Yujiri T, Shinohara K, Inoue Y, Sato Y, Fujii Y, Okubo M, Zaitsu Y, Ariyoshi K, Nakamura Y, et al. Molecular mimicry by Helicobacter pylori CagA protein may be involved in the pathogenesis of H. pylori-associated chronic idiopathic thrombocytopenic purpura. Br J Haematol 2004;124:91–96
   PubMed Web of Science ®Google Scholar
• Jackson S, Beck PL, Pineo GF, Poon MC. Helicobacter pylori eradication: Novel therapy for immune thrombocytopenic purpura? Review of the literature. Am J Hematol 2005;78:142–150
   PubMedGoogle Scholar
• Yeh JJ, Tsai S, Wu DC, Wu JY, Liu TC, Chen A. P-selectin-dependent platelet aggregation and apoptosis may explain the decrease in platelet count during Helicobacter pylori infection. Blood 2010;115:4247–4253
   PubMed Web of Science ®Google Scholar
• Veneri D, De Matteis G, Solero P, Federici F, Zanuso C, Guizzardi E, Arena S, Gaio M, Pontiero P, Ricetti MM, et al. Analysis of B- and T-cell clonality and HLA class II alleles in patients with idiopathic thrombocytopenic purpura: Correlation with Helicobacter pylori infection and response to eradication treatment. Platelets 2005;16:307–311
   PubMed Web of Science ®Google Scholar
• Asahi A, Nishimoto T, Okazaki Y, Suzuki H, Masaoka T, Kawakami Y, Ikeda Y, Kuwana M. Helicobacter pylori eradication shifts monocyte Fcγ receptor balance toward inhibitory FcγRIIB in immune thrombocytopenic purpura patients. J Clin Invest 2008;118:2939–2949
   PubMed Web of Science ®Google Scholar
• Suzuki T, Matsushima M, Shirakura K, Koike J, Masui A, Takagi A, Shirasugi Y, Ogawa Y, Shirai T, Mine T. Association of inflammatory cytokine gene polymorphisms with platelet recovery in idiopathic thrombocytopenic purpura patients after the eradication of Helicobacter pylori. Digestion 2008;77:73–78
   PubMed Web of Science ®Google Scholar
• Ohguchi H, Kameoka J, Harigae H, Yamada M, Takahashi S, Ishizawa K, Sano N, Sekine H, Sasaki T. Can the Helicobacter pylori eradication regimen induce PLT recovery in H. pylori-negative patients with idiopathic thrombocytopenic purpura? Am J Hematol 2005;78:164–165
   PubMedGoogle Scholar
• Arnold DM, Stasi R. Does Helicobacter pylori eradication therapy result in a PLT count improvement in adults with immune thrombocytopenic purpura regardless of H. pylori infection? Hematol Am Soc Hematol Educ Program 2008:31–32
   PubMedGoogle Scholar
• Tsustumi Y, Kanamori H, Yamato H, Ehira N, Kawamura T, Umehara S, Mori A, Obara S, Ogura N, Tanaka J, et al. Randomized study of Helicobacter pylori eradication therapy and proton pump inhibitor monotherapy for idiopathic thrombocytopenic purpura. Ann Hematol 2005;84:807–811
   PubMedGoogle Scholar
• Ohe M, Satoshi S. Successful treatment with erythromycin for idiopathic thrombocytopenic purpura. Korean J Hematol 2011;46:139–142
   PubMedGoogle Scholar
• Jackson SC, Beck P, Buret AG, O'Connor PM, Meddings J, Pineo G, Poon MC. Long term platelet responses to Helicobacter pylori eradication in Canadian patients with immune thrombocytopenic purpura. Int J Hematol 2008;88:212–218
   PubMed Web of Science ®Google Scholar
• Kohda K, Kuga T, Kogawa K, Kanisawa Y, Koike K, Kuroiwa G, Hirayama Y, Sato Y, Niitsu Y. Effect of Helicobacter pylori eradication on platelet recovery in Japanese patients with chronic idiopathic thrombocytopenic purpura and secondary autoimmune thrombocytopenic purpura. Br J Haematol 2002;118:584–588
   PubMed Web of Science ®Google Scholar
• Ando K, Shimamoto T, Tauchi T, Ito Y, Kuriyama Y, Gotoh A, Kimura Y, Kawai T, Ohyashiki K. Can eradication therapy for Helicobacter pylori really improve the thrombocytopenia in idiopathic thrombocytopenic purpura? Our experience and a literature review. Int J Hematol 2003;77:239–244
   PubMed Web of Science ®Google Scholar
• Suvajdzic N, Stankovic B, Artiko V, Cvejic T, Bulat V, Bakrac M, Colovic M, Obradovic V, Atkinson HD. Helicobacter pylori eradication can induce platelet recovery in chronic thrombocytopenic purpura. Platelets 2006;17:227–230
   PubMed Web of Science ®Google Scholar
• Campuzano-Maya G. Proof of an association between Helicobacter pylori and idiopathic thrombocytopenic purpura in Latin America. Helicobacter 2007;12:265–273
   PubMed Web of Science ®Google Scholar