282
Views
8
CrossRef citations to date
0
Altmetric
Original Article

Novel mutations of integrin αIIb and β3 genes in Turkish children with Glanzmann’s thrombasthenia

, , &
Pages 779-782 | Received 14 Oct 2014, Accepted 10 Dec 2014, Published online: 03 Mar 2015

References

  • Di Minno G, Coppola A, Di Minno MN, Poon MC. Glanzmann's thrombasthenia (defective platelet integrin alphaIIb-beta3): Proposals for management between evidence and open issues. Thromb Haemost 2009;102:1157–1164
  • Bellucci S, Caen J. Molecular basis of Glanzmann's thrombasthenia and current strategies in treatment. Blood Rev 2002;16:193–202
  • Kannan M, Saxena R. Glanzmann's thrombasthenia: An overview. Clin Appl Thromb Hemost 2009;15:152–165
  • Zimrin AB, Gidwitz S, Lord S, Schwartz E, Bennett JS, White GC II, Poncz M. The genomic organization of platelet glycoprotein IIIa. J Biol Chem 1990;265:8590–8595
  • French DL, Coller BS. Hematologically important mutations: Glanzmann thrombasthenia. Blood Cells Mol Dis 1997;23:39–51
  • Pillitteri D, Pilgrimm AK, Kirchmaier CM. Novel mutations in the ΑIIband Β3 genes in Glanzmann thrombasthenia. Transfus Med Hemother 2010;37:268–277
  • Bray PF, Rosa JP, Lingappa VR, Kan YW, McEver RP, Shuman MA. Biogenesis of the platelet receptor for fibrinogen: Evidence for separate precursors for glycoproteins IIb and IIIa. Proc Natl Acad Sci U S A 1986;83:1480–1484
  • Lambert MP, Poncz M. 2009. Inherited platelet disorders. In: Orkin SH, Nathan DG, Ginsburg D, Look AT, Fisher DE, Lux SE, editors. Hematology of infancy and childhood, 7th edn. Philadelphia, PA: Saunders Elsevier. pp 1464–1476
  • Xiao T, Takagi J, Coller BS, Wang JH, Springer TA. Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature 2004;432:59–67
  • George JN, Caen JP, Nurden AT. Glanzmann's thrombasthenia: The spectrum of clinical disease. Blood 1990;75:1383–1395
  • D'Andrea G, Margaglione M. Glanzmann's thrombasthenia: Modulation of clinical phenotype by alpha2C807T gene polymorphism. Haematologica 2003;88:1378–1382

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.