11
Views
17
CrossRef citations to date
0
Altmetric
Review Article

Platelet Heterogeneity and Coronary Artery Thrombosis

&
Pages 11-17 | Published online: 07 Jul 2009

References

  • Steering Committee of the Physicians' Health Study Research Group. Final Report on the aspirin component of the ongoing Physicians' Health Study. N Engl J Med 1989; 321: 129–135
  • Lewis H D, David J W, Archibald D G, et al. Protective effect of aspirin against acute myocardial infarction and death in men with unstable angina. Results of Veteran Administration cooperative study. N Engl J Med 1983; 309: 396–403
  • Cairns J A, Gent M, Singer J, et al. Aspirin, sulfinpyrazone or both in unstable angina. N Engl J Med 1985; 313: 1369–1375
  • Theroux P, Ouimet H, McCans J, et al. Aspirin, heparin, or both to treat acute unstable angina. N Engl J Med 1988; 319: 1105–1111
  • ISIS-2 collaborative group. Randomised trial of intravenous streptokinase, oral aspirin, both, or neither, among 17 187 cases of suspected acute myocardial infarction: ISIS-2. Lancet 1988; ii: 349–360
  • Husted S E, Nielsen H K, Krusell L R, Faergeman O. Acetylsalicylic acid 100 and 1000 mg daily for the prevention of coronary thrombosis. A placebo-controlled clinical trial. J Int Med 1989; 226: 303–310
  • Falk E. Plaque rupture with pre-existing stenosis precipitating coronary thrombosis. Characteristics of coronary atherosclerotic plaques underlying fatal occlusive thrombi. Br Heart J 1983; 50: 127–134
  • Davies M J, Thomas A C. Thrombosis and acute coronaryartery lesions in sudden cardiac death. N Engl J Med 1984; 310: 1137–1140
  • Falk E. Unstable angina with fatal outcome, dynamic coronary thrombosis leading to infarction and/or sudden death. Autopsy evidence of recurrent mural thrombosis with peripheral embolization culminating in total vascular occlusion. Circulation 1985; 71: 699–708
  • Martin J F, Trowbridge A E. Platelet Heterogeneity: Biology and Pathology. Spring Verlag, London 1990
  • Martin J F, Penington D G. The relationship between the age and density of circulating 51-Cr labelled platelets in the sub-human primate. Thromb Res 1983; 30: 157–164
  • Thompson C B, Love D G, Quinn P G, Valeri C R. Platelet size does not correlate with platelet age. Blood 1983c; 62: 487–494
  • Boughton B J, Macwhannell A, Simpson A, Hawker R. Platelet size and adenine nucleotides in patients undergoing bone marrow ablation: A useful model for studying platelet ageing. Platelets 1990; 1: 21–24
  • Karpatkin S. Heterogeneity of human platelets. I. Metabolic and kinetic evidence suggestive of young and old platelets. J Clin Invest 1969; 48: 1073–1082
  • Karpatkin S. Heterogeneity of human platelets. II. Functional evidence suggestive of young and old platelet. J Clin Invest 1969; 48: 1083–1087
  • Corash L, Tan H, Gralnick H R. Heterogeneity of human whole blood thrombokinetics to bone marrow megakaryocytes in idiopathic thrombocytopenic purpura (ITP). Blood 1975; 45: 551–562
  • Corash L, Shafer B, Perlow K. Heterogeneity of human whole blood platelet subpopulations. II. Use of a subhuman primale model to analyse the relationship between density and platelet age. Blood 1978; 52: 726–734
  • Martin J F, Shaw T, Heggie J, Penington D G. Measurement of the density of human platelets and its relationship to volume. Br J Haematol 1983; 54: 337–352
  • Martin J F., Paulus J M. The meaning and control of megakaryocyte polyploidy. International Journal of Cell Cloning 1990, in press
  • Trowbridge E A, Martin J F, Slater D N, et al. The origin of platelet count and volume. Clin Phys Physiol Meas 1984; 5: 145–170
  • Cramer E M, Debili N, Martin J F, et al. Uncoordinated expression of fibrinogen compared with thrombospondin and von Willebrand factor in maturing human megakaryocytes. Blood 1989; 73(5)1123–1129
  • Handagama P J, Bainton D F. Incorporation of a circulating protein into alpha granules of megakaryocytes. Blood 1989; 15: 59–72
  • Odell T T, Murphy J R., Jackson C W. Stimulation of megakaryocytopoiesis by acute thrombocytopenia in rats. Blood 1976; 48: 765–775
  • Martin J F, Trowbridge E A, Salmon G, Plumb J. The biological significance of platelet volume: its relationship to bleeding time, platelet thromboxane B2 production and megakaryocyte DNA concentration. Thromb Res 1983; 32: 443–460
  • Trowbridge E A, Warren C W, Martin J F. Platelet volume heterogeneity in acute thrombocytopenia. Clin Phys Physiol Meas 1986; 7: 203–210
  • Corash L, Chen H Y, Levin J, Baker G, Liu H., Mok Y. Regulation of thrombopoiesis: effects of the degree of thrombocytopenia on megakaryocyte ploidy and platelet volume. Blood 1987; 70: 177–185
  • Haver V M, Gear A R L. Functional fractionation of platelets. J Lab Clin Med 1981; 97: 187–204
  • Thompson C B., Eaton K A, Princiotta S M, Kushkin C A., Valeri C R. Size dependent platelet subpopulations: relationship of platelet volume to ultrastructure, enzymatic activity and function. Br J Haematol 1982; 50: 509–519
  • Thompson C B, Jakubowski J A., Quinn P G, Deykin D, Valeri C R. Platelet size as a determinant of platelet function. J Lab Clin Med 1983; 101: 205–213
  • Jakubowski J A, Thompson C B, Vailancourt R., Valeri C R, Deykin D. Arachidonic acid metabolism by platelets of differing size. Br J Haematol 1983; 53: 503–511
  • Kristensen S D, Milner P C, Martin J F. Bleeding time and platelet volume in acute myocardial infarction—a 2 year follow-up study. Thromb Haemostas 1988; 59: 353–356
  • Thorngren M, Shafi S, Born G R V. Thromboxane A2 in skin-bleeding-time-blood and in clotted venous blood before and after administration of acetylsalicylic acid. Lancet 1983; i: 1075–1078
  • Gerrard J M, Taback S, Singroy S, et al. In vivo measurement of thromboxane B2 and 6-keto-prostaglandin F1 α in humans in response to a standardized vascular injury and the influence of aspirin. Circulation 1989; 79: 29–38
  • Kristensen S D., Bath P M W, Martin J F. The bleeding time is inversely related to megakaryocyte nuclear DNA content and size in man. Thromb Haemostas 1988b; 59: 357–359
  • Martin J F. The relationship between platelet volume and megakaryocyte ploidy. Blood Cells 1989; 15: 108–117
  • Harker L A. Thrombokinetics in idiopathic thrombocytopenic purpura. Br J Haematol 1970; 19: 95–105
  • Branehog I, Kutti J., Weinfeld A. Platelet survival and platelet production in idiopathic thrombocytopenic purpura (ITP). Br J Haematol 1974; 27: 127–143
  • Schmidt K G, Rasmussen J W. Kinetics and distribution in vivo of 111–In-labelled autologous platelets in idiopathic thrombocytopenic purpura. Scand J Haemat 1985; 34: 47–56
  • Nelson R B, Kehl D. Electronically determined platelet indices in thrombocytopenic patients. Cancer 1981; 48: 954–956
  • Bessman J D. The relationship of megakaryocyte ploidy to platelet volume. Am J Haematol 1984; 16: 161–170
  • Pfueller S L, Chesterman C, Illes I, Hussein S, Martin J. F. Relationship of platelet-associated immunoglobulin G and platelet protein to platelet size and density in normal individuals and patients with thrombocytopenia. J Lab Clin Med 1986; 107: 299–305
  • Branehog I, Kutti J, Ridell B, Swolin B, Weinfeld A. The relation of thrombokinetics to bone marrow megakaryocytes in idiopathic thrombocytopenic purpura (ITP). Blood 1975; 45: 551–562
  • Kristensen S D, Roberts K M, Kishk Y T, Martin J F. Accelerated atherogenesis occurs following platelet destruction and increases in megakaryocyte size and DNA content. Eur. J Clin Invest 1990; 20: 239–247
  • Eldor A, Avitzour M, Or R, Hanna R, Penchas S. Prediction of haemorrhagic diathesis in thrombocytopenia by mean platelet volume. Br Med J 1982; 285: 397–400
  • Thompson C B. Selective consumption of large platelets during massive bleeding. Br J Med 1985; 291: 95–96
  • Kishk Y T, Trowbridge E A, Martin J F. Platelet volume subpopulation in acute myocardial infarction: an investigation of their heterogeneity for smoking infarct size and site. Clin Sci 1985; 68: 419–425
  • Fagher B, Sjogren A, Sjogren U. Platelet counts in myocardial infarction, angina pectoris and peripheral artery disease. Acta Med Scand 1985; 217: 21–26
  • Glud T, Schmidt E B, Kristensen S D, Arnfred T. Platelet number and volume during myocardial infarction in relation to infarct size. Acta Med Scand 1986; 220: 401–405
  • Kutti J, Weinfeld A. Platelet survival and platelet production in acute myocardial infarction. Acta Med Scand 1979; 205: 501–504
  • Ruf W, McNamara J J, Suehiro A, Suehiro G, Wickline S A. Platelet trapping in myocardial infarct in baboons: therapeutic effect of aspirin. Am J Cardiol 1980; 46: 405–412
  • Martin J F, Plumb J, Kilbey R S, Kishk Y T. Changes in volume and density of platelets in myocardial infarction. Br Med J 1983; 287: 456–459
  • Cameron H A, Philips R, Ibbotson R M., Carson P H M. Platelet size in myocardial infarction. Br Med J 1983; 287: 449–451
  • Erne P, Wardle J, Sanders K, Lewis S M, Maseri A. Mean platelet volume and size distribution and their sensitivity to agonists in patients with coronary artery disease and congestive heart failure. Thromb Haemostas 1988; 59: 259–263
  • Trowbridge E A, Martin J F. The platelet volume distribution: a signature of the prethrombotic state in coronary heart disease?. Thromb Heamostas 1987; 58: 714–717
  • Sewell R, Ibbotson R M, Philips R., Carson P. High mean platelet volume after myocardial infarction: is it due to consumption of small platelets?. Br Med J 1984; 289: 1576–1578
  • Thompson C B, Diaz D D, Quinn P G., Lapins M., Kurtz S R, Valeri C R. The role of anticoagulation in the measurement of platelet volumes. Am J Clin Pathol 1983; 80: 327–332
  • Trowbridge E A, Reardon D M, Hutchinson D, Pickering C. The routine measurement of platelet volume: a comparison of light-scattering and aperture-impedance technologies. Clin Phys Physiol Meas 1985; 6: 221–238
  • Milner P C, Martin J F. Shortened bleeding time in myocardial infarction and its relation to platelet mass. Br J Med 1985; 290: 1767–1770
  • Szczeklik A., Milner P C, Birch J, Watkins J, Martin J F. Prolonged bleeding time, reduced platelet aggregation, altered PAF-Acether sensitivity and increased platelet mass are a trait of asthma and hay fever. Thromb Haemostas 1986; 56(3)283–287
  • Mielke C H. Measurement of the bleeding time. Thromb Haemostas 1984; 52: 210–211
  • Kristensen S D, Bath P M W, Martin J F. Differences in bleeding time and aspirin sensitivity and adrenaline between acute myocardial infarction and unstable angina. Cardiovasc Res 1990; 24: 19–23
  • O'Brien J R, Ethrington M E., Jamieson S, Klaber M R. Stressed template bleeding time and other platelet function lests in myocardial infarction. Lancet 1973; i: 694–696
  • Vesterquist O, Edhag Green, Henriksson P. In vivo production of thromboxane in acute myocardial infarction: a preliminary study. Thromb Res 1985; 37: 459–464
  • Fitzgerald D J., Roy L, Catella F, Fitzgerald G A. Platelet activation in unstable coronary disease. N Engl J Med 1986; 315: 983–989
  • Henriksson P, Wennmalm A, Edhag O, Vesterquist O, Green K. In vivo production of prostacyclin and thromboxane in patients with acute myocardial infarction. Br Heart J 1986; 55: 543–548
  • Rasmanis G, Vesterquist O, Green K, Edhag O, Henriksson P. Effects of intermittent treatment with aspirin on thromboxane and prostacyclin formation in patients with acute myocardial infarction. Lancet 1988; ii: 245–247
  • Trowbridge E A, Slater D N, Kishk Y T, Woodcock B W, Martin J F. Platelet production of myocardial infarction and sudden cardiac death. Thromb Haemostas 1984; 52: 167–171

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.