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Original Article

Original Article: Intracellular Ca2+ Mobilization and Aggregatory Response to ADP and Thrombin in Aged Rat Platelets

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Pages 388-393 | Published online: 07 Jul 2009

References

  • Hallam T J., Rink T J. Response to adenosine diphosphate in human platelets loaded with the fluorescent calcium indicator quin2. J Physiol 1985; 368: 131–146
  • Magócsi M, Sarkadi B, Kovács T, Gárdos G. Thrombin-induced activation of calcium transport pathways and their role in platelet functions. Biochim Biophys Acta 1989; 984: 88–94
  • Mahaut-Smith M P., Sage S O., Rink T J. Receptor-activated single channels in intact human platelets. J Biol Chem 1990; 265: 10479–10483
  • Vlachakis N D., Aledort F L. Hypertension and propranolol therapy: effect on blood pressure, plasma catecholamines and platelet aggregation. Am J Cardiol 1980; 45: 321–325
  • Scarabin P Y., Samama M. Damad study research group: effect of age on ADP-induced platelet aggregation in diabetic and non-diabetic subjects. Thromb Res 1981; 22: 687–692
  • Ishii H, Umeda F, Hashimoto T, Nawata H. Changes in phosphoinositide turnover, Ca2+ mobilization, and protein phosphorylation in platelets from NIDDM patients. Diabetes 1990; 39: 1561–1568
  • Riess H, Merck W, Faker C., Hiller E. Increased in vitro platelet aggregation in hypertriglyceridemias. Thromb Res 1986; 37: 281–289
  • Erne P, Bolli P, Bürgisser E, Bühler F R. Correlation of platelet calcium with blood pressure. N Engl J Med 1984; 310: 1084–1088
  • Lechi A, Lechi C., Bonadonna G, et al. Increased basal and thrombin-induced free calcium in platelets of essential hypertensive patients. Hypertension 1987; 9: 230–235
  • Tschöpe D, Rosen P, Gries F A. Increase in the cytosolic concentration of calcium in platelets of diabetics type II. Thromb Res 1991; 62: 421–428
  • Vilén L, Jacobson S, Wadenvik H, Kutti J. ADP-induced platelet aggregation as a function of age in healthy humans. Thromb Haemost 1989; 61: 490–492
  • Yokoyama M, Kusui A, Sakamoto S, Fukuzaki H. Age-associated increments in human platelet a-adrenoceptor capacity. Thromb Res 1984; 34: 287–295, Possible mechanism for platelet hyperactivity to epinephrine in aging man
  • Gleerup G, Winter K. The effect of aging on human platelet sensitivity to serotonin. Eur J Clin Invest 1988; 18: 504–506
  • Vericel E, Croset M, Sedivy P, Courpron P, Dechavanne M, Lagarde M. Platelets and aging I - aggregation, arachidonate metabolism and antioxidant status. Thromb Res 1988; 49: 331–342
  • Terres W, Weber K, Kupper W, Bleifeld W. Age, cardiovascular risk factors and coronary heart disease as determination of platelet function in men. Thromb Res 1991; 62: 649–661, A multivariate approach
  • Sugidachi A, Asai F, Oshima T, Koike H. Age-associated changes in intracellular Ca2+ mobilization and basal pH level in rat platelets. Platelets 1993; 4: 91–95
  • Goodwin J E. Estimation of plasma fibrinogen using sodium sulfate fraction. Am J Clin Pathol 1961; 35: 227–232
  • Ito T, Asai F, Oshima T, Kobayashi S. Role of activated platelets in endotoxin-induced DIC in rats. Thromb Res 1990; 59: 735–747
  • Takasaki W, Nakagawa A, Asai F, et al. Superiority of plasma 11-dehydro-TXB2 to TXB2 as an index of in vivo TX formation in rabbits after dosing of CS-518, a TX synthase inhibitor. Thromb Res 1993; 71: 69–76
  • Hashimoto Y, Ogihara A, Nakanishi S, Matsuda Y, Kurokawa K, Nonomura Y. Two thrombin-activated Ca2+ channels in human platelets. J Biol Chem 1992; 267: 17078–17081
  • Grynkiewicz G, Poenie M, Tsuien Y. A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem 1985; 260: 340–3450
  • Marguerie G A., Plow E F., Edington T S. Human platelets possess an inducible and a saturable receptor specific for fibrinogen. J Biol Chem 1979; 254: 5357–5363
  • Packham M A., Bryant N L., Guccione M A., Kinlough-Rathbone R L., Mustard J F. Effects of the concentration of Ca2+ in the suspending medium on the response of human and rabbit platelets to aggregating agents. Thromb Haemost 1989; 62: 968–976
  • Cavallini L, Francesconi M A., Ruzzene M, Valente M, Deana R. A procedure allowing measurement of cytoplasmic Ca2+ in rat platelets. Inhibition of a plasma lipoprotein on fura 2-AM loading. Thromb Res 1991; 63: 47–57
  • Deshmukh D S., Kuizon S, Brockerhoff H. Barbiturates inhibit intracellular Ca2+ rise induced by thrombin in rat platelets. Cell Calcium 1991; 12: 645–654
  • Kramer R M., Jakubowski J A., Vaillancourt R., Deykin D. Effect of membrane cholesterol on phospholipid metabolism in thrombin-stimulated platelets. J Biol Chem 1982; 257: 684–6849
  • Meade T W., Vickers M V., Thompson S G., Stiring Y, Haines A P., Miller G J. Epidemiological characteristics of platelet aggregability. BMJ 1985; 290: 428432
  • Giani E, Masi I, Galli C. Platelets from aged rats aggregate more, but are more sensitive to prostacyclin. Prostaglandin Leukotr Med 1985; 20: 237–246
  • Wey H, Gallon L, Subbiah M. T.R. Prostaglandin synthesis in aorta and platelets of fawn-hooded rats with platelet storage pool disease and its response to cholesterol feeding. Thromb Haemost 1982; 48: 94–97
  • Tschopp T B., Zucker M B. Hereditary defect in platelet function in rats. Blood 1972; 40: 217–266
  • Emms H, Lewis G P. The role of prostaglandin endoperoxides, thromboxane A, and adenosine diphosphate in collagen-induced aggregation in man and the rat. Br J Pharmacol 1986; 87: 109–115
  • Schrör K. The basic pharmacology of ticlopidine and clopidogrel. Platelets 1993; 4: 252–261
  • Defreyn G, Bernat A, Delebassee D, Maffrand J-P. Pharmacology of ticlopidine: a review. Semin Thromb Hemost 1989; 15: 159–166
  • Vickers J D., Kinlough-Rathbone R L., Packham M A., Mustard J F. Inositolphospholipid metabolism in human platelets stimulated by ADP. Eur J Biochem 1990; 193: 521–528
  • Siffert W, Siffert G, Scheid P, Akkerman J W. Activation of Na/H exchange and Ca2mobilization start simultaneously in thrombin-stimulated platelets. Biochem J 1989; 258: 521–527
  • Gachet C., Cazenave J P. ADP induced blood platelet activation: a review. Nouv Rev Fr Hematol 1991; 33: 347–358
  • Ware A, Clark B A., Smith M, Sahan E W. Abnormalities of cytoplasmic Ca2+ in platelets from patients with uremia. Blood 1989; 73: 172–176
  • Ikeda M, Onda T, Tomita I, Tomita T. Reduced functions of intracellular Ca2+ in aggregation, secretion and protein phosphorylation of permeabilized platelets from stroke-prone spontaneously hypertensive rats. Thromb Res 1992; 67: 655–663
  • Baba A, Fukuda K, Kuchii M, et al. Intracellular free calcium concentration, Ca++ channel and calmodulin level in experimental hypertension in rats. Jpn Circ J 1987; 51: 1216–1222
  • George J N., Pickett E B., Saucerman S, et al. Platelet surface glycoproteins: studies on resting and activated platelets in patients during adult respiratory distress syndrome and cardiac surgery. J Clin Invest 1986; 78: 340–348

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