Enabling a multidisciplinary approach to the study of ageing and Alzheimer's disease: An update from the Australian Imaging Biomarkers and Lifestyle (AIBL) study

References

• Abbott, R.D., White, L.R., Ross, G.W., Masaki, K.H., Curb, J.D. & Petrovitch, H. (2004). Walking and dementia in physically capable elderly men. Journal of the American Medical Association, 292, 1447–1453.
   PubMed Web of Science ®Google Scholar
• Acosta, O., Fripp, J., Doré, V., Bourgeat, P., Favreau, J.M., Chételat, G., … Salvado, O. (2012). Cortical surface mapping using topology correction, partial flattening and 3D shape context-based non-rigid registration for use in quantifying atrophy in Alzheimer's disease. Journal of Neuroscience Methods, 205, 96–109.
   PubMed Web of Science ®Google Scholar
• AD International. (2010). The Global Economic Impact of Dementia. London: Alzheimer's Disease International.
   Google Scholar
• Adlard, P.A., Perreau, V.M., Pop, V. & Cotman, C.W. (2005). Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease. Journal of Neuroscience, 25, 4217–4221.
   PubMed Web of Science ®Google Scholar
• Ancelin, M.L., Artero, S., Portet, F., Dupuy, A.M., Touchon, J. & Ritchie, K. (2006). Non-degenerative mild cognitive impairment in elderly people and use of anticholinergic drugs: Longitudinal cohort study. British Medical Journal, 332, 455–459.
   PubMed Web of Science ®Google Scholar
• Andrews, K.A., Modat, M., Macdonald, K.E., Yeatman, T., Cardoso, M.J., Leung, K.K., … Schott, J.M. (2013). Atrophy rates in asymptomatic amyloidosis: Implications for Alzheimer prevention trials. PLOS ONE, 8. doi: 10.1371/journal.pone.0058816
   Web of Science ®Google Scholar
• Bacskai, B.J., Frosch, M.P., Freeman, S.H., Raymond, S.B., Augustinack, J.C., Johnson, K.A., … Growdon, J.H. (2007). Molecular imaging with Pittsburgh Compound B confirmed at autopsy: A case report. Archives of Neurology, 64, 431–434.
   PubMed Web of Science ®Google Scholar
• Bottiggi, K.A., Salazar, J.C., Yu, L., Caban-Holt, A.M., Ryan, M., Mendiondo, M.S. & Schmitt, F.A. (2006). Long-term cognitive impact of anticholinergic medications in older adults. American Journal of Geriatric Psychiatry, 14, 980–984.
   PubMed Web of Science ®Google Scholar
• Bourgeat, P., Chételat, G., Villemagne, V.L., Fripp, J., Raniga, P., Pike, K., … Salvado, O. (2010). Beta-amyloid burden in the temporal neocortex is related to hippocampal atrophy in elderly subjects without dementia. Neurology, 74, 121–127.
   PubMed Web of Science ®Google Scholar
• Bowen, R.L., Isley, J.P. & Atkinson, R.L. (2000). An association of elevated serum gonadotropin concentrations and Alzheimer disease?Journal of Neuroendocrinology, 12, 351–354.
   PubMed Web of Science ®Google Scholar
• Bowen, R.L., Verdile, G., Liu, T., Parlow, A.F., Perry, G., Smith, M.A., … Atwood, C.S. (2004). Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition. Journal of Biological Chemistry, 279, 20539–20545.
   PubMed Web of Science ®Google Scholar
• Brown, B.M., Peiffer, J.J., Sohrabi, H.R., Mondal, A., Gupta, V.B., Rainey-Smith, S.R., … Martins, R.N. (2012a). Intense physical activity is associated with cognitive performance in the elderly. Translational Psychiatry, 2, e191.
   PubMed Web of Science ®Google Scholar
• Brown, B.M., Peiffer, J.J., Taddei, K., Lui, J.K., Laws, S.M., Gupta, V.B., … Martins, R.N. (2012b). Physical activity and amyloid-beta plasma and brain levels: Results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing. Molecular Psychiatry, 18, 875–881.
   PubMed Web of Science ®Google Scholar
• Buckley, R., Saling, M.M., Ames, D., Rowe, C.C., Lautenschlager, N.T., Macaulay, S.L., … Ellis, K.A. (2013). Factors affecting subjective memory complaints in the AIBL aging study: Biomarkers, memory, affect, and age. International Psychogeriatrics, 25, 1307–1315.
   PubMed Web of Science ®Google Scholar
• Burnham, S.C., Faux, N.G., Wilson, W., Laws, S.M., Ames, D., Bedo, J., … Villemagne, V.L. (2013). A blood-based predictor for neocortical Abeta burden in Alzheimer's disease: Results from the AIBL study. Molecular Psychiatry. doi: 10.1038/mp.2013.40
   Web of Science ®Google Scholar
• Cancelli, I. (2010). Anticholinergic drugs increase the risk of cognitive decline and dementia in older people. Evidence-Based Mental Health, 13, 44.
   PubMedGoogle Scholar
• Cancelli, I., Beltrame, M., Gigli, G.L. & Valente, M. (2009). Drugs with anticholinergic properties: Cognitive and neuropsychiatric side-effects in elderly patients. Neurological Sciences, 30, 87–92.
   PubMed Web of Science ®Google Scholar
• Cancelli, I., Gigli, G.L., Piani, A., Zanchettin, B., Janes, F., Rinaldi, A. & Valente, M. (2008). Drugs with anticholinergic properties as a risk factor for cognitive impairment in elderly people: A population-based study. Journal of Clinical Psychopharmacology, 28(6), 654–659.
   PubMed Web of Science ®Google Scholar
• Capitani, E., Cazzaniga, R., Francescani, A. & Spinnler, H. (2004). Cognitive deterioration in Alzheimer's disease: Is the early course predictive of the later stages?Neurological Sciences, 25(4), 198–204.
   PubMed Web of Science ®Google Scholar
• Chételat, G., Villemagne, V.L., Bourgeat, P., Pike, K.E., Jones, G., Ames, D., … Rowe, C.C. (2010a). Relationship between atrophy and beta-amyloid deposition in Alzheimer disease. Annals of Neurology, 67, 317–324.
   PubMed Web of Science ®Google Scholar
• Chételat, G., Villemagne, V.L., Pike, K.E., Baron, J.C., Bourgeat, P., Jones, G., … Rowe, C.C. (2010b). Larger temporal volume in elderly with high versus low beta-amyloid deposition. Brain, 133, 3349–3358.
   PubMed Web of Science ®Google Scholar
• Chételat, G., Villemagne, V.L., Pike, K.E., Ellis, K.A., Bourgeat, P., Jones, G., … Rowe, C.C. (2011). Independent contribution of temporal beta-amyloid deposition to memory decline in the pre-dementia phase of Alzheimer's disease. Brain, 134(3), 798–807.
   PubMedGoogle Scholar
• Chételat, G., Villemagne, V.L., Villain, N., Jones, G., Ellis, K.A., Ames, D., … Rowe, C.C. (2012). Accelerated cortical atrophy in cognitively normal elderly with high beta-amyloid deposition. Neurology, 78, 477–484.
   PubMed Web of Science ®Google Scholar
• Chiu, H.F. & Brodaty, H. (2013). Arguments against the biomarker-driven diagnosis of AD. International Psychogeriatrics, 25, 177–181.
   PubMed Web of Science ®Google Scholar
• Clarke, R., Smith, A.D., Jobst, K.A., Refsum, H., Sutton, L. & Ueland, P.M. (1998). Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease. Archives of Neurology, 55, 1449–1455.
   PubMed Web of Science ®Google Scholar
• Crook, T.H. III, Feher, E.P. & Larrabee, G.J. (1992). Assessment of memory complaint in age-associated memory impairment: The MAC-Q. International Psychogeriatrics, 4, 165–176.
   PubMedGoogle Scholar
• Doecke, J.D., Laws, S.M., Faux, N.G., Wilson, W., Burnham, S.C., Lam, C.P., … Martins, R.N. (2012). Blood-based protein biomarkers for diagnosis of Alzheimer disease. Archives of Neurology, 69(10), 1318–1325.
   PubMedGoogle Scholar
• Doody, R.S., Massman, P. & Dunn, J.K. (2001). A method for estimating progression rates in Alzheimer disease. Archives of Neurology, 58, 449–454.
   PubMedGoogle Scholar
• Doré, V., Villemagne, V.L., Bourgeat, P., Fripp, J., Acosta, O., Chételat, G., … Rowe, C.C. (2013). Cross-sectional and longitudinal analysis of the relationship between Aβ deposition, cortical thickness, and memory in cognitively unimpaired individuals and in Alzheimer disease. Journal of the American Medical Association Neurology, 70(7), 903–911.
   Google Scholar
• Egan, M.F., Kojima, M., Callicott, J.H., Goldberg, T.E., Kolachana, B.S., Bertolino, A., … Weinberger, D.R. (2003). The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell, 112, 257–269.
   PubMed Web of Science ®Google Scholar
• Ellis, K.A., Bush, A.I., Darby, D., De Fazio, D., Foster, J., Hudson, P., … Ames, D. (2009). The Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging: Methodology and baseline characteristics of 1112 individuals recruited for a longitudinal study of Alzheimer's disease. International Psychogeriatrics, 21, 672–687.
   PubMed Web of Science ®Google Scholar
• Ellis, K.A., Lim, Y.Y., Harrington, K., Ames, D., Bush, A.I., Darby, D., … Maruff, P. (2013). Decline in cognitive function over 18 months in healthy older adults with high amyloid-beta. Journal of Alzheimer's Disease, 34, 861–871.
   PubMed Web of Science ®Google Scholar
• Erickson, K.I., Voss, M.W., Prakash, R.S., Basak, C., Szabo, A., Chaddock, L., … Kramer, A.F. (2011). Exercise training increases size of hippocampus and improves memory. Proceedings of the National Academy of Sciences of the United States of America, 108, 3017–3022.
   PubMed Web of Science ®Google Scholar
• Fagan, A.M., Mintun, M.A., Mach, R.H., Lee, S.Y., Dence, C.S., Shah, A.R., … Holtzman, D.M. (2006). Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans. Annals of Neurology, 59, 512–519.
   PubMed Web of Science ®Google Scholar
• Fahnestock, M. (2011). Brain-derived neurotrophic factor: The link between amyloid-β and memory loss. Future Neurology, 6, 627–639.
   Google Scholar
• Faux, N.G., Ellis, K.A., Porter, L., Fowler, C.J., Laws, S.M., Martins, R.N., … Bush, A.I. (2011). Homocysteine, vitamin B12, and folic acid levels in Alzheimer's disease, mild cognitive impairment, and healthy elderly: Baseline characteristics in subjects of the Australian Imaging Biomarker Lifestyle study. Journal of Alzheimer's Disease, 27, 909–922.
   PubMed Web of Science ®Google Scholar
• Feart, C., Samieri, C., Rondeau, V., Amieva, H., Portet, F., Dartigues, J.F., … Barberger-Gateau, P. (2009). Adherence to a Mediterranean diet, cognitive decline, and risk of dementia. Journal of the American Medical Association, 302, 638–648.
   PubMed Web of Science ®Google Scholar
• Flicker, C., Ferris, S.H. & Serby, M. (1992). Hypersensitivity to scopolamine in the elderly. Psychopharmacology, 107, 437–441.
   PubMed Web of Science ®Google Scholar
• Fripp, J., Bourgeat, P., Acosta, O., Raniga, P., Modat, M., Pike, K.E., … Ourselin, S. (2008a). Appearance modeling of 11C PiB PET images: characterizing amyloid deposition in Alzheimer's disease, mild cognitive impairment and healthy aging. NeuroImage, 43, 430–439.
   PubMed Web of Science ®Google Scholar
• Fripp, J., Bourgeat, P., Raniga, P., Acosta, O., Villemagne, V., Jones, G., … Salvado, O. (2008b). MR-less high dimensional spatial normalization of 11C PiB PET images on a population of elderly, mild cognitive impaired and Alzheimer disease patients. Medical Image Computing and Computer Assisted Intervention, 11, 442–449.
   PubMedGoogle Scholar
• Gardener, S., Gu, Y., Rainey-Smith, S.R., Keogh, J.B., Clifton, P.M., Mathieson, S.L., … Martins, R.N. (2012). Adherence to a Mediterranean diet and Alzheimer's disease risk in an Australian population. Translational Psychiatry2, e164.
   PubMed Web of Science ®Google Scholar
• Garzon, D.J. & Fahnestock, M. (2007). Oligomeric amyloid decreases basal levels of brain-derived neurotrophic factor (BDNF) mRNA via specific downregulation of BDNF transcripts IV and V in differentiated human neuroblastoma cells. Journal of Neuroscience, 27, 2628–2635.
   PubMed Web of Science ®Google Scholar
• Gupta, V.B., Laws, S.M., Villemagne, V.L., Ames, D., Bush, A.I., Ellis, K.A., … Martins, R.N. (2011). Plasma apolipoprotein E and Alzheimer disease risk: The AIBL study of aging. Neurology, 76, 1091–1098.
   PubMed Web of Science ®Google Scholar
• Han, L., Agostini, J.V. & Allore, H.G. (2008). Cumulative anticholinergic exposure is associated with poor memory and executive function in older men. Journal of the American Geriatrics Society, 56, 2203–2210.
   PubMed Web of Science ®Google Scholar
• Hariri, A.R., Goldberg, T.E., Mattay, V.S., Kolachana, B.S., Callicott, J.H., Egan, M.F. & Weinberger, D.R. (2003). Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance. Journal of Neuroscience, 23, 6690–6694.
   PubMed Web of Science ®Google Scholar
• Holland, J., Bandelow, S. & Hogervorst, E. (2011). Testosterone levels and cognition in elderly men: A review. Maturitas, 69, 322–337.
   PubMed Web of Science ®Google Scholar
• Ikonomovic, M.D., Klunk, W.E., Abrahamson, E.E., Mathis, C.A., Price, J.C., Tsopelas, N.D., … DeKosky, S.T. (2008). Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease. Brain, 131(6), 1630–1645.
   PubMedGoogle Scholar
• Kalmijn, S., Launer, L.J., Lindemans, J., Bots, M.L., Hofman, A. & Breteler, M.M. (1999). Total homocysteine and cognitive decline in a community-based sample of elderly subjects: The Rotterdam Study. American Journal of Epidemiology, 150, 283–289.
   PubMed Web of Science ®Google Scholar
• Kant, A.K. (1996). Indexes of overall diet quality: A review. Journal of the American Dietetic Association, 96, 785–791.
   PubMed Web of Science ®Google Scholar
• Klunk, W.E., Engler, H., Nordberg, A., Wang, Y., Blomqvist, G., Holt, D.P., … Langstrom, B. (2004). Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Annals of Neurology, 55, 306–319.
   PubMed Web of Science ®Google Scholar
• Larson, E.B., Wang, L., Bowen, J.D., McCormick, W.C., Teri, L., Crane, P. & Kukull, W. (2006). Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older. Annals of Internal Medicine, 144, 73–81.
   PubMed Web of Science ®Google Scholar
• Lautenschlager, N.T., Cox, K.L., Flicker, L., Foster, J.K., van Bockxmeer, F.M., Xiao, J., … Almeida, O.P. (2008). Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: A randomized trial. Journal of the American Medical Association, 300, 1027–1037.
   PubMed Web of Science ®Google Scholar
• Le Couteur, D.G., Doust, J., Creasey, H. & Brayne, C. (2013). Political drive to screen for pre-dementia: Not evidence based and ignores the harms of diagnosis. BMJ, 347, f5125.
   PubMed Web of Science ®Google Scholar
• Leinonen, V., Alafuzoff, I., Aalto, S., Suotunen, T., Savolainen, S., Nagren, K., … Rinne, J.O. (2008). Assessment of beta-amyloid in a frontal cortical brain biopsy specimen and by positron emission tomography with carbon 11-labeled Pittsburgh Compound B. Archives of Neurology, 65, 1304–1309.
   PubMed Web of Science ®Google Scholar
• Lim, Y.Y., Ellis, K.A., Ames, D., Darby, D., Harrington, K., Martins, R.N., … Maruff, P. (2012a). Abeta amyloid, cognition, and APOE genotype in healthy older adults. Alzheimer's and Dementia. doi: 10.1016/j.jalz.2012.07.004
   PubMed Web of Science ®Google Scholar
• Lim, Y.Y., Ellis, K.A., Harrington, K., Kamer, A., Pietrzak, R.H., Bush, A.I., … Maruff, P. (2013a). Cognitive consequences of high Abeta amyloid in mild cognitive impairment and healthy older adults: Implications for early detection of Alzheimer's disease. Neuropsychology, 27, 322–332.
   PubMed Web of Science ®Google Scholar
• Lim, Y.Y., Ellis, K.A., Harrington, K., Pietrzak, R.H., Gale, J., Ames, D., … Maruff, P. (2013b). Cognitive decline in adults with amnestic mild cognitive impairment and high amyloid-beta: Prodromal Alzheimer's disease?Journal of Alzheimer's Disease, 33, 1167–1176.
   PubMed Web of Science ®Google Scholar
• Lim, Y.Y., Ellis, K.A., Pietrzak, R.H., Ames, D., Darby, D., Harrington, K., … Maruff, P. (2012b). Stronger effect of amyloid load than APOE genotype on cognitive decline in healthy older adults. Neurology, 79, 1645–1652.
   PubMed Web of Science ®Google Scholar
• Lim, Y.Y., Villemagne, V.L., Laws, S.M., Ames, D., Pietrzak, R.H., Ellis, K.A., … Maruff, P. (2013c). BDNF Val66Met, Abeta amyloid, and cognitive decline in preclinical Alzheimer's disease. Neurobiology of Aging, 34(11), 2457–2464.
   PubMed Web of Science ®Google Scholar
• Lui, J.K., Laws, S.M., Li, Q.X., Villemagne, V.L., Ames, D., Brown, B., … Group, A.R. (2010). Plasma amyloid-beta as a biomarker in Alzheimer's disease: The AIBL study of aging. Journal of Alzheimer's Disease, 20, 1233–1242.
   PubMed Web of Science ®Google Scholar
• Mielke, M.M., Leoutsakos, J.M., Corcoran, C.D., Green, R.C., Norton, M.C., Welsh-Bohmer, K.A., … Lyketsos, C.G. (2012). Effects of Food and Drug Administration-approved medications for Alzheimer's disease on clinical progression. Alzheimer's and Dementia, 8, 180–187.
   PubMed Web of Science ®Google Scholar
• Minati, L., Edginton, T., Bruzzone, M.G. & Giaccone, G. (2009). Current concepts in Alzheimer's disease: A multidisciplinary review. American Journal of Alzheimer's Disease and Other Dementias, 24, 95–121.
   PubMed Web of Science ®Google Scholar
• Morris, J.C., Aisen, P.S., Bateman, R.J., Benzinger, T.L., Cairns, N.J., Fagan, A.M., … Buckles, V.D. (2012). Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network. Clinical Investigation, 2, 975–984.
   PubMedGoogle Scholar
• Nordberg, A., Carter, S.F., Rinne, J., Drzezga, A., Brooks, D.J., Vandenberghe, R., … Herholz, K. (2013). A European multicentre PET study of fibrillar amyloid in Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging, 40, 104–114.
   PubMed Web of Science ®Google Scholar
• Ortega, R.M., Requejo, A.M., Andres, P., Lopez-Sobaler, A.M., Quintas, M.E., Redondo, M.R., … Rivas, T. (1997). Dietary intake and cognitive function in a group of elderly people. American Journal of Clinical Nutrition, 66, 803–809.
   PubMed Web of Science ®Google Scholar
• Oulhaj, A., Refsum, H., Beaumont, H., Williams, J., King, E., Jacoby, R. & Smith, A.D. (2010). Homocysteine as a predictor of cognitive decline in Alzheimer's disease. International Journal of Geriatric Psychiatry, 25, 82–90.
   PubMed Web of Science ®Google Scholar
• Peng, S., Wuu, J., Mufson, E.J. & Fahnestock, M. (2005). Precursor form of brain-derived neurotrophic factor and mature brain- derived neurotrophic factor are decreased in the preclinical stages of Alzheimer's disease. Journal of Neurochemistry, 93, 1412–1421.
   PubMed Web of Science ®Google Scholar
• Petersen, R.C., Roberts, R.O., Knopman, D.S., Boeve, B.F., Geda, Y.E., Ivnik, R.J., … Jack, C.R., Jr. (2009). Mild cognitive impairment: ten years later. Archives of Neurology, 66, 1447–1455.
   PubMed Web of Science ®Google Scholar
• Pike, K.E., Ellis, K.A., Villemagne, V.L., Good, N., Chételat, G., Ames, D., … Rowe, C.C. (2011). Cognition and beta-amyloid in preclinical Alzheimer's disease: Data from the AIBL study. Neuropsychologia, 49, 2384–2390.
   PubMed Web of Science ®Google Scholar
• Rabinovici, G.D., Furst, A.J., O’Neil, J.P., Racine, C.A., Mormino, E.C., Baker, S.L., … Jagust, W.J. (2007). 11C-PIB PET imaging in Alzheimer disease and frontotemporal lobar degeneration. Neurology, 68, 1205–1212.
   PubMed Web of Science ®Google Scholar
• Raniga, P., Bourgeat, P., Fripp, J., Acosta, O., Villemagne, V.L., Rowe, C., … Ourselin, S. (2008). Automated (11)C-PiB standardized uptake value ratio. Academic Radiology, 15, 1376–1389.
   PubMed Web of Science ®Google Scholar
• Reid, L.M. & Maclullich, A.M. (2006). Subjective memory complaints and cognitive impairment in older people. Dementia and Geriatric Cognitive Disorders, 22, 471–485.
   PubMed Web of Science ®Google Scholar
• Reiman, E.M., Langbaum, J.B. & Tariot, P.N. (2010). Alzheimer's prevention initiative: A proposal to evaluate presymptomatic treatments as quickly as possible. Biomarkers in Medicine, 4, 3–14.
   PubMed Web of Science ®Google Scholar
• Rembach, A., Doecke, J.D., Roberts, B.R., Watt, A.D., Faux, N.G., Volitakis, I., … Bush, A.I. (2012). Longitudinal analysis of serum copper and ceruloplasmin in Alzheimer's Disease. Journal of Alzheimer's Disease, 34(1), 171–182.
   Web of Science ®Google Scholar
• Rembach, A., Faux, N.G., Watt, A.D., Pertile, K.K., Rumble, R.L., Trounson, B.O., … Masters, C.L. (2013). Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease. Alzheimer's and Dementia. doi: 10.1016/j.jalz.2012.12.006
   PubMed Web of Science ®Google Scholar
• Riggs, K.M., Spiro, A. III, Tucker, K. & Rush, D. (1996). Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study. American Journal of Clinical Nutrition, 63, 306–314.
   PubMed Web of Science ®Google Scholar
• Roberts, J.L., Clare, L. & Woods, R.T. (2009). Subjective memory complaints and awareness of memory functioning in mild cognitive impairment: A systematic review. Dementia and Geriatric Cognitive Disorders, 28, 95–109.
   PubMed Web of Science ®Google Scholar
• Rowe, C.C., Ellis, K.A., Rimajova, M., Bourgeat, P., Pike, K.E., Jones, G., … Villemagne, V.L. (2010). Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging. Neurobiology of Aging, 31, 1275–1283.
   PubMed Web of Science ®Google Scholar
• Rowe, C.C., Ng, S., Ackermann, U., Gong, S.J., Pike, K., Savage, G., … Villemagne, V.L. (2007). Imaging beta-amyloid burden in aging and dementia. Neurology, 68, 1718–1725.
   PubMed Web of Science ®Google Scholar
• Rowe, C.C. & Villemagne, V.L. (2011). Brain amyloid imaging. Journal of Nuclear Medicine, 52, 1733–1740.
   PubMed Web of Science ®Google Scholar
• Scarmeas, N., Stern, Y., Tang, M.X., Mayeux, R. & Luchsinger, J.A. (2006). Mediterranean diet and risk for Alzheimer's disease. Annals of Neurology, 59, 912–921.
   PubMed Web of Science ®Google Scholar
• Schneider, L.S., Insel, P.S. & Weiner, M.W. (2011). Treatment with cholinesterase inhibitors and memantine of patients in the Alzheimer's Disease Neuroimaging Initiative. Archives of Neurology, 68, 58–66.
   PubMedGoogle Scholar
• Sona, A., Zhang, P., Ames, D., Bush, A.I., Lautenschlager, N.T., Martins, R.N., … Ellis, K.A. (2012). Predictors of rapid cognitive decline in Alzheimer's disease: Results from the Australian imaging, biomarkers and lifestyle (AIBL) study of ageing. International Psychogeriatrics, 24, 197–204.
   PubMed Web of Science ®Google Scholar
• Sperling, R.A., Aisen, P.S., Beckett, L.A., Bennett, D.A., Craft, S., Fagan, A.M., … Phelps, C.H. (2011). Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging–Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's and Dementia, 7, 280–292.
   PubMed Web of Science ®Google Scholar
• Squitti, R. (2012). Metals in alzheimer's disease: A systemic perspective. Frontiers in Bioscience, 17, 451–472.
   Web of Science ®Google Scholar
• Verdile, G., Laws, S.M., Henley, D., Ames, D., Bush, A.I., Ellis, K.A., … Martins, R.N. (2012). Associations between gonadotropins, testosterone and beta amyloid in men at risk of Alzheimer's disease. Molecular Psychiatry.doi: 10.1038/mp.2012.147
   Web of Science ®Google Scholar
• Villain, N., Chételat, G., Grassiot, B., Bourgeat, P., Jones, G., Ellis, K.A., … Villemagne, V.L. (2012). Regional dynamics of amyloid-beta deposition in healthy elderly, mild cognitive impairment and Alzheimer's disease: A voxelwise PiB-PET longitudinal study. Brain, 135(7), 2126–2139.
   PubMedGoogle Scholar
• Villemagne, V.L., Burnham, S., Bourgeat, P., Brown, B., Ellis, K.A., Salvado, O., … Masters, C.L. (2013). Amyloid beta deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: A prospective cohort study. Lancet Neurology, 12(4), 357–367.
   PubMed Web of Science ®Google Scholar
• Villemagne, V.L., Fodero-Tavoletti, M.T., Pike, K.E., Cappai, R., Masters, C.L. & Rowe, C.C. (2008). The ART of Loss: Aβ imaging in the evaluation of Alzheimer's disease and other dementias. Molecular Neurobiology, 38, 1–15.
   PubMed Web of Science ®Google Scholar
• Villemagne, V.L., Pike, K.E., Chételat, G., Ellis, K.A., Mulligan, R.S., Bourgeat, P., … Rowe, C.C. (2011). Longitudinal assessment of Aβ and cognition in aging and Alzheimer disease. Annals of Neurology, 69, 181–192.
   PubMed Web of Science ®Google Scholar
• Wahjoepramono, E.J., Wijaya, L.K., Taddei, K., Bates, K.A., Howard, M., Martins, G., … Martins, R.N. (2011). Direct exposure of guinea pig CNS to human luteinizing hormone increases cerebrospinal fluid and cerebral beta amyloid levels. Neuroendocrinology, 94, 313–322.
   PubMed Web of Science ®Google Scholar
• Wahjoepramono, E.J., Wijaya, L.K., Taddei, K., Martins, G., Howard, M., de Ruyck, K., … Martins, R.N. (2008). Distinct effects of testosterone on plasma and cerebrospinal fluid amyloid-beta levels. Journal of Alzheimer's Disease, 15, 129–137.
   PubMed Web of Science ®Google Scholar
• Weiner, M.W., Veitch, D.P., Aisen, P.S., Beckett, L.A., Cairns, N.J., Green, R.C., … Trojanowski, J.Q. (2012). The Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception. Alzheimer's and Dementia, 8, S1–68.
   PubMed Web of Science ®Google Scholar
• Yates, P.A., Sirisriro, R., Villemagne, V.L., Farquharson, S., Masters, C.L. & Rowe, C.C. (2011). Cerebral microhemorrhage and brain {beta}-amyloid in aging and Alzheimer disease. Neurology, 77, 48–54.
   PubMed Web of Science ®Google Scholar
• Zhou, L., Salvado, O., Doré, V., Bourgeat, P., Raniga, P., Villemagne, V. L., … Fripp, J. (2012). MR-less surface-based amyloid estimation by subject-specific atlas selection and Bayesian fusion. Medical Image Computing and Computer Assisted Intervention, 15(2), 220–227.
   PubMedGoogle Scholar