Schizophrenia Research: attempting to integrate genetics, neurodevelopment and nosology

References

• Abrams R., Taylor M. A. The genetics of schizophrenia, a reassessment using modern criteria. American Journal of Psychiatry 1983; 140: 171–175
   Google Scholar
• Andrew B., Watt D. C., Gillespie C., Chapel H. A study of genetic linkage in schizophrenia. Psychological Medicine 1987; 17(2)363–370
   Google Scholar
• Bassett A. S., McGillivray B. C., Jones B. D., Pantzar J. T. Partial trisomy chromosome 5 cosegregating with schizophrenia. The Lancet 1988; i: 799–780
   Google Scholar
• Bogerts B. The neuropathology of schizophrenia. Developmental Neuropathology of Schizophrenia, S. A. Mednick. Plenum, New York 1990, in press)
   Google Scholar
• Book J. A., Wetterberg L., Modrzewska K. Schizophrenia in a North Swedish geographical isolate. Epidemiology, genetics and biochemistry, Clinical Genetics 1978; 14: 1900–1977; 373–394
   Google Scholar
• Botstein D., White R. L., Skolnick M., Davis R. W. Construction of a genetic linkage map in man using restriction fragment length polymorphisms. American Journal of Human Genetics 1980; 32: 314–331
   PubMed Web of Science ®Google Scholar
• Brockington I. F., Kendell R. E., Leff J. P. Definitions of schizophrenia: concordance and prediction of outcome. Psychological Medicine 1978; 8: 387–398
   PubMed Web of Science ®Google Scholar
• Canon T. D., Mednick S. A., Parnas J. Genetic and perinatal determinants of structural brain deficits in schizophrenia. Archives of General Psychiatry 1989; 46: 883–889
   Google Scholar
• Clerget-Darpoux E., Bonaiti-Pellie C., Hochez J. Effects of misspecifying genetic parameters in LOD score analysis. Biometrics 1986; 42: 393–399
   PubMed Web of Science ®Google Scholar
• Collinge J., Boccio A., DeLisi L. E., Johnstons E. C., Lofthouse R., Owen F., Poulter M., Risby D., Shah T., Crow T. J. A pseudo-autosomal locus for schizophrenia. Paper presented at the First World Congress on Psychiatric Genetics. Cambridge 1989
   Google Scholar
• Coryell W., Zimmerman M. The hentability of schizophrenia and schizoaffective disorder. Archives of General Psychiatry 1988; 45: 377–383
   Google Scholar
• Crow T. J. The continuum of psychosis and its implication for the structure of the gene. British Journal of Psychiatry 1986; 149: 419–429
   PubMed Web of Science ®Google Scholar
• DeLisi L. E., Goldin L. R., Maxwell E., Kazuba D. M., Gershon E. S. Clinical features of illness in siblings with schizophrenia or schizoaffective disorder. Archives of General Psychiatry 1987; 44: 891–896
   Google Scholar
• Edwards J. H., Watt D. C. Caution in locating the gene(s) for affective disorder. Psychological Medicine 1989; 19: 273–275
   PubMedGoogle Scholar
• Egeland J. A., Gerhard D. S., Pauls D. L., Sussex J. N., Kidd K. K., Allen C. R., Hostetter A. M., Houseman D. E. Bipolar affective disorders linked to DNA markers on chromosome 11. Nature 1987; 325: 783–787
   PubMed Web of Science ®Google Scholar
• Elston R. C., Kringlen E., Namboodiri K. K. Possible linkage relationships between certain blood groups and schizophrenia or other psychoses. Behavioral Genetics 1973; 3: 101–106
   PubMedGoogle Scholar
• Farmer A. E., Jackson R., McGuffin P., Storey P. Cerebral ventricular enlargement in chronic schizophrenia: consistencies and contradictions. British Journal of Psychiatry 1987b; 150: 324–440
   PubMed Web of Science ®Google Scholar
• Farmer A. E., McGuffin P., Jackson R., Storey P. Classifying schizophrenia (letter. The Lancet 1985; 1: 1333
   Google Scholar
• Farmer A. E., McGuffin P., Gottesman 1. I. Twin concordance for DSM III schizophrenia. Archives of General Psychiatry 1987a; 44: 634–641
   PubMed Web of Science ®Google Scholar
• Goodman R. Neuronal missconnections and psychiatric disorder. British Journal of Psychiatry 1989; 154: 292–299
   PubMedGoogle Scholar
• Gottesman I. I., Bertelson A. Confirming unexpressed genotypes for schizophrenia: risks in the offspring of Fischer's Danish identical and fraternal discordant twins. Archives of General Psychiatry 1989; 46: 867–872
   PubMed Web of Science ®Google Scholar
• Gottesman I. I., Shields J. Schizophrenia: The Epigenetic Puzzle. Cambridge University Press, Cambridge 1982
   Google Scholar
• Gottesman I. I., Shields J. Schizophrenia and genetics: a twin study vantage point. Academic Press, London 1972
   Google Scholar
• Grandy D. K., Liti M., Allen L., Bunzow J. R., Marchionni M., Makam H., Reed L., Magenis R. E., Civelli O. Assignment of the human dopamine D2 receptor gene to chromosome 11. American Journal of Human Genetics 1989; 45: 778–785
   PubMed Web of Science ®Google Scholar
• Green J. R., Woodrow J. C. Sibling method for detecting HLA-linked genes in disease. Tissue Antigens 1977; 9: 31–35
   Google Scholar
• Heckenlively J. R. Retinitis Pigmentosa. J. B. Lippincott, London 1988
   Google Scholar
• Hodge S. E., Spence M. A. Some epistatic two-locus models of disease. II The confounding of linkage and association. American Journal of Human Genetics 1981; 22: 396–406
   Google Scholar
• Holt I. J., Harding A. E., Middleton L., Chrysostomou G., Said G., King R. H., Thomas P. K. Molecular genetics of amyloid neuropathy in Europe. The Lancet 1989; i: 524–526
   Google Scholar
• Jacob H., Beckman H. Prenatal developmental disturbances in the limbic allocortex in schizophrenics. Journal of Neural Transmission 1986; 65: 303–326
   PubMed Web of Science ®Google Scholar
• Karlson J. L. Partially dominant transmission of schizophrenia in Iceland. British Journal of Psychiatry 1988; 152: 324–329
   Google Scholar
• Kaufmann C. A., Powchik P., Freimer N., Bassett A. S., Wasmuth J., Gilliam T. C. Schizophrenia and chromosome 5: molecular mapping of the region containing a putative susceptibility locus. Schizophrenia Research 1989; 2: 42
   Google Scholar
• Kelsoe J. R., Ginns E. I., Egeland J. A., Goldstein A. M., Bale S. J., Pauls D. L., Long R. T., Conte G., Gerhard D. S., Houseman D. E., Paul S. M. Re-evaluation of the linkage relationship between chromosome 11p loci and the gene for bipolar affective disorder in the old order Amish. Nature 1989; 42: 238–243
   Google Scholar
• Kendell R. E., Kemp I W. Maternal influenza in the etiology of schizophrenia. Archives of General Psychiatry 1989; 46: 872–882
   Google Scholar
• Kennedy J. L., Giuffra L. A., Moises H. W., Cavallisforza L. L., Pakstis A. J., Kidd J. R., Castiglione C. M., Sjogren B., Wetterberg L., Kidd K. K. Evidence against linkage of schizophrenia to markers on chromosome 5 in a northern Swedish pedigree. Nature 1988; 336: 167–169
   PubMed Web of Science ®Google Scholar
• Kendler K. S. The feasibility of linkage studies in schizophrenia. Biological Perspectives in Psychiatry, H. Helmchen, F. A. Henn. John Wiley, Chichester 1987
   Google Scholar
• Kendler K. S. Familial aggregation of schizophrenia and schizophrenia spectrum disorders. Archives of General Psychiatry 1988a; 45: 323–327
   Google Scholar
• Kendler K. S. The sporadic v familial classification given aetiological heterogeneity: II Power analysis. Psychological Medicine 1988b; 18: 991–999
   Google Scholar
• Kendler K. S. Limitations of the ratio in concordance rates in monozygotic and dizygotic twins. Archives of General Psychiatry 1989; 46: 477–478
   PubMedGoogle Scholar
• Kendler K. S., Gruenberg A. M., Tsuang M. T. Psychiatric illness in first degree relatives of schizophrenics and surgical control patients. Archives of General Psychiatry 1985; 42: 770–779
   PubMed Web of Science ®Google Scholar
• Kendler K. S., Gruenberg A. M., Tsuang M. T. An independent analysis of the Copenhagen sample of the Danish adoption study of schizophrenia. II: The relationship between schizotypal personality disorder and schizophrenia. Archives of General Psychiatry 1981; 38: 982–984
   PubMedGoogle Scholar
• Kendler K. S., Hays P. Schizophrenia subdivided by the family history of affective disorder: a comparison of symptomatology and course of illness. Archives of General Psychiatry 1983; 40: 951–955
   PubMed Web of Science ®Google Scholar
• Kendler K. S., Tsuang M. T. Outcome and family psychopathology in schizophrenia. Archives of General Psychiatry 1988; 45: 338–346
   Google Scholar
• Keshaven M., Toone B. K., Marshall W., Shazly M. E., Palin M. Neuroendocrine dysfunction in schizophrenia: a familial perspective. Psychiatry Research 1988; 23: 345–348
   Google Scholar
• Kety S. S., Rosenthal D., Wender P. H. Mental illness in the biological and adoptive families of individuals who have become schizophrenic. Behavior Genetics 1976; 6: 219–225, et al.
   PubMed Web of Science ®Google Scholar
• Kety S. S., Rosenthal D., Wender P. H., Schulsinger F., Jacobsen B. Mental illness in the biological and adoptive families of adopted individuals who have become schizophrenic. Genetic Research in Psychiatry, R. R. Fieve, D. Rosenthal, H. Brill. Johns Hopkins University Press, Baltimore 1975
   Google Scholar
• Lander E. S., Botstein D. Strategies for studying heterogeneous genetic traits in humans by using a linkage map of restriction fragment length polymorphisms. Procedures of the National Academy of Sciences. USA 1986; 83: 7353–7357
   Google Scholar
• Lewis S. W., Murray R. M. Obstetric complications, neurodevelopmental deviance and risk of schizophrenia. Journal of Psychiatric Research 1987; 21: 413–421
   PubMed Web of Science ®Google Scholar
• Lewis S. W., Murray R. M., Owen M. Obstetric complications in schizophrenia: methodology and mechanisms. S. C. Schultz, T. A. Tamminga. 1989, in press (Eds) Proceedings of the First World Congress on Schizophrenia ResearchOxfordOxford University Press
   Google Scholar
• Lewis S. W., Reveley M. A., David A. S., Ron M. A. Agenesis of the Corpus Callosum and schizophrenia. Psychological Medicine 1988; 18: 341–347
   PubMed Web of Science ®Google Scholar
• Lewis S. W., Mezey G. C. Clinical correlates of septum pellucidum cavities. Psychological Medicine 1985; 15: 43–54
   PubMed Web of Science ®Google Scholar
• McGue M., Gottesman I. I. Genetic linkage in schizophrenia. Schizophrenia Bulletin 1989; 15: 453–464
   PubMed Web of Science ®Google Scholar
• McGuffin P., Festenstein H., Murray R. A family study of HLA antigens and other genetic markers in schizophrenia. Psychological Medicine 1983; 13: 31–43
   PubMed Web of Science ®Google Scholar
• McGuffin P., Farmer A. E., Gottesman I. I., Murray R. M., Reveley A. M. Twin concordance for operationally defined schizophrenia. Archives of General Psychiatry 1984; 41: 541–545
   PubMed Web of Science ®Google Scholar
• McGuffin P., Farmer A. E., Gottesman I. I. Is there really a split in schizophrenia. British Journal of Psychiatry 1987; 150: 587–592
   Google Scholar
• McNeill T. F. Schizophrenic head size at birth. Paper presented at the 4th. Biennial Winter on Schizophrenia. BadgasteinAustria 1988
   Google Scholar
• Mednick S. A., Machon R. A., Huttunen M. O., Bonnet D. Adult schizophrenia following prenatal exposure to an influenza epidemic. Archives of General Psychiatry 1988; 45: 189–192
   PubMed Web of Science ®Google Scholar
• Mendlewttz J., Linowski P., Wilmotte J. Linkage between glucose-6-phosphate dehydrogenase deficiency and manic-depressive psychosis. British Journal of Psychiatry 1980; 137: 337–342
   Google Scholar
• Monaco A. P., Bertelson C. J., Middlesworth W., Colletti C-A., Aldridge J., Fischbeck K. H., Bartlett R., Pericac-Vance M. A., Roses A. D., Kunkel L. M. Detection of deletions spanning the Duchenne muscular dystrophy locus using a tightly linked DNA segment. Nature 1985; 316: 642–645
   Google Scholar
• Murray R. M., Lewis S., Reveley A. M. Towards an aetiological classification of schizophrenia. The Lancet 1985; i: 1023–1026
   Google Scholar
• Murray R. M., Reveley A. M., McGuffin P. Genetic vulnerability to schizophrenia. Psychiatric Clinics of North America 1986; 9(1)3–16
   Google Scholar
• Murray R. M., Foerster A. Schizophrenia: Is the concept disintegrating. Journal of Psychopharmacology 1987; 1: 133–139
   Google Scholar
• Murray R. M., Lewis S. W., Owen M. J., Foerster A. The neurodevelopmental origins of dementia praecox. Schizophrenia, the Major Issues, P. Bebbington, P. McGuffin. William Heinemann, London 1988
   Google Scholar
• Nimgaonkar V. L., Wessley S., Murray R. M. Prevalence of familiality, obstetric complications and structural brain damage in schizophrenic patients. Psychological Medicine 1988; 18: 583–592
   Google Scholar
• Nowakowski R. S. Basic concepts of CNS development. Child Development 1989; 58: 568–595
   Google Scholar
• O'Callaghan E., Larkin C., Waddington J. L. Clinical correlates of obstetric complications in schizophrenia. Schizophrenia Research 1989; 1: 125
   Google Scholar
• Orkin S. H. Reverse genetics and human disease. Cell 1986; 47: 845–850
   PubMed Web of Science ®Google Scholar
• Ott J. Linkage analysis and family classification under heterogeneity. Annals of Human Genetics 1983; 47: 311–320
   Google Scholar
• Owen M. J., Lewis S. W., Murray R. M. Family history and cerebral ventricular enlargement in schizophrenia: a case control study. British Journal of Psychiatry 1989; 154: 629–634
   Google Scholar
• Owen M. J., Perrett C. W., Whatley S. A. The effects of cis-and trans-flupenthixol upon gene expression in the rat brain: a study of the mechanism of action of antipsychotic drugs. Schizophrenia Research 1988; 1: 219–220
   Google Scholar
• Perrett C. W., Marchbanks R. M., Wathley S. W. Postmortem messenger RNA analysis in control and psychiatric subjects. Schizophrenia Research 1988; 1: 13–16
   Google Scholar
• Ray P. N., Belfall B., Duff C., Logan C., Kean V., Thompson M. W., Sylvester J. E., Gorski J. L., Schmickel R. D., Whorton R. G. Cloning of the breakpoint of an X:21 translocation associated with Duchenne muscular dystrophy. Nature 1985; 318: 672–675
   PubMed Web of Science ®Google Scholar
• Reveley A. M., Chitkara B. Subtypes in schizophrenia (letter. The Lancet 1985; i: 1503
   Google Scholar
• Reveley A. M., Reveley M. A., Clifford C. A., Murray R. M. Cerebral ventricular size in twins discordant for schizophrenia. The Lancet 1982; i: 540–541
   Google Scholar
• Reveley A. M., Reveley M. A., Murray R. M. Cerebral ventricular enlargement in non-genetic schizophrenia: a controlled twin study. British Journal of Psychiatry 1984; 144: 89–93
   PubMedGoogle Scholar
• Riordan J. R., Rommens J. M., Kerem B-S., Alon N., Rozmahel R., Grzelczak Z., Zielenski J., Lok S., Plavsic N., Chou J-L., Drumm M. L., Iannuzzi M. C., Collins F. F., Tsui L-C. Identification of the Cystic Fibrosis gene: cloning and characterization of complimentary DNA. Science 1989; 245: 1066–1073
   PubMed Web of Science ®Google Scholar
• Roberts G. W., Done D. J., Bruton C., Crow T. J. A ‘mock-up’ of schizophrenia: temporal lobe epilepsy and schizophrenia-like psychosis. Biological Psychiatry 1989, in press
   Google Scholar
• Rosenthal D. Genetic Theory and Abnormal Behavior. McGraw-Hill, New York 1970
   Google Scholar
• Sacchetti E., Vita A., Calzeroni A., Invernizzi G., Cazullo C. L. Neuromorphological correlates of schizophrenic disorders. Etiopathogenic Hypotheses of Schizophrenia, L. T. Cazullo. MTP Press, Lancaster 1987
   Google Scholar
• St Clair D., Blackwood D., Muir W., Baillie D., Hubbard A., Wright A., Evans H. J. No linkage of chromosome 5q11-q13 markers to schizophrenia in Scottish families. Nature 1989; 339: 305–309
   PubMed Web of Science ®Google Scholar
• Schwartzkopf S. B., Nasrallah H. A., Olson S. C., Coffman J. C., McIaughlin J. A. MRI brain measures in familial vs. sporadic schizophrenics. Paper presented at the Annual Meeting of the American Psychiatric Association, San Fransisco, 1989
   Google Scholar
• Shelton R. C., Weinberger D. R. X-ray computerised tomography studies in schizophrenia: a review and synthesis. The Neurology of Schizophrenia, H. A. Nasrallah, D. R. Weinberger. Elsevier, Amsterdam 1986
   Google Scholar
• Sherrington R., Brynjolfsson J., Petersson H., Potter M., Dudleston K., Barraclough B., Wasmuth J., Dobbs M., Gurling H. Localization of a susceptibility locus for schizophrenia on chromosome 5. Nature 1988; 336: 164–167
   PubMed Web of Science ®Google Scholar
• Slater E., Beard A. W., Glithero E. The schizophrenic like psychoses of epilepsy. British Journal of Psychiatry 1963; 109: 95–150
   PubMed Web of Science ®Google Scholar
• Suarez B., O'Rourke D., Van Eederwegh P. Power of the affected-sib-pair method to detect disease susceptibility loci of small effect: an application to multiple sclerosis. American Journal of Medical Genetics 1982; 12: 309–326
   Google Scholar
• Tsuang M. T., Lyons M. J. Drawing the boundary of schizophrenic spectrum. Schizophrenia: Scientific Progress, S. C. Schulz, T. A. Tamminga. Oxford University Press, New York 1989
   Google Scholar
• Turner S. W., Toone B. K., Brett-Jones R. CT scan changes in early schizophrenia. Psychological Medicine 1986; 16: 219–225
   PubMedGoogle Scholar
• Turner W. H. Genetic markers for schizotaxia. Biological Psychiatry 1979; 14: 177–206
   Google Scholar
• Wilcox J. A., Nasrallah H. A. Perinatal distress and prognosis of psychotic illness. Neuropsychobiology 1987; 17: 173–175
   PubMed Web of Science ®Google Scholar
• Witkowski J. A. The molecular genetics of Duchenne muscular dystrophy: the beginning of the end. Trends in Genetics 1988; 4(2)27–30
   Google Scholar