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Original Article

Criteria for Assessing Novel Modes of Antidepressant Drug Action in Man

Pages 193-205 | Published online: 11 Jul 2009

References

  • Anderson I. M., Cowen P. J. Chromipramine enhances prolactin and growth hormone responses to L-tryptophan. Psychopharmacology 1986; 8(9)131–133
  • Batra Biorklund S. A. Binding affinities of four tricyclic antidepressive drugs to muscarinic cholinergic receptors in human parotid gland. Psychopharmacology 1986; 90: 1–4
  • Bearn J. A., Franey C, Arendt J., Checkley S. A. A study of the effect of desipramine treatment alone and in combination with tri-iodorhyromine on 6-sulphatoxymelatonin excretion in depressed patients. British Journal of Psychiatry 1989; 15(5)341–347
  • Benfield P., Heel R. C., Lewis S. P. Fluoxetine: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in depressive illness. Drugs 1986; 3(2)481–508
  • Benfield P, Ward A. Fluvoxamine: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in depressive illness. Drugs 1986; 3(2)313–334
  • Borbely A. A., Trachsel L., Tobler I. Effect of ritanserin on sleep stages and sleep EEG in the rat. European Journal of Pharmacology 1988; 15(6)275–278
  • Bowsher D. J., Rowe H., Farid N. A., Tenbarge J. B., Lemberger L. Pressor responses to Tyramine and Norepinephrine after subchronic administration of Fluoxetine in man. Life Sciences 1988; 4(2)2569–2575
  • Cassidy S, Henry J. Fatal toxicity of antidepressant drugs in overdose. British Medical Journal 1987; 29(5)1021–1024
  • Charig E. M., Anderson I. M., Robinson J. M., Nutt D. J., Cowen P. J. L-Tryptophan and prolactin release: evidence for interaction between 5-HT1and 5-HT1receptors. Human Psychopharmacology 1986; 1: 93–97
  • Checkley S. A., Thompson C., Burton S., Franey C., Arendt J. Clinical studies of the effect of (+)- and (−) oxaprotiline upon noradrenaline uptake. Psychopharmacology 1985; 8(7)117–118
  • Checkley S. A., Corn T. H., Glass I. B., Burton S. W., Burke C. A. The responsiveness of central alpha-2 adrenoceptors in depression. The Biology of Depression, J. F. W. Deakin, T. Crow. London, Gaskell 1952; 100–120
  • Checkley S. A., Corn T. H., Glass I. B., Thompson C., Franey C., Arendt J. Neuroendocrine and other studies of the mechanism of action of desipramine. A Foundation Symposium 1986; 12(3)126–147
  • Checkley S. A., Park S. B. G. The psychophar-macology of the human pineal. Journal of Psychopharmacology 1986; 1: 20–22
  • Checkley S. A., Winton F., Franey C., Arendt J. Effects of a phosphodiesterase inhibitor upon the urinary excretion of 6-sulphatoxy melatonin in man. Journal of Psychopharmacology 1987; 1: 20–22
  • Cohn J. B., Wilcox C. S., Meltzer H. Y. Neuroendocrine effects of Buspirone in patients with generalised anxiety disorder. American Journal of Medicine 1986; 80: 36–40
  • Corn T. H. Reversible inhibitors of monoamine oxidase A: antidepressants without cheese effect?. International Review of Psychiatry 1987; 2: 187–192
  • Cowen P. J., Green A. R., Grahame-Smith D. G., Braddock L. E. Plasma melatonin during desmethylimipramine treatment: evidence for changes in noradrenergic neurotransmission. British Journal of Pharmacology 1985; 1(9)799–805
  • Curran H. V., Lader M. H. The psychophar-macological effects of repeated doses of Fluvoxamine, Mianserin and Placebo in healthy human subjects. European Journal of Clinical Pharmacology 1990; 29: 601–607
  • De Boer, Th. Maura M., Ratters G., de Vos C. J., Wieringa J., Pinder R. M. Neurochemical and autonomic phamacological profiles of the 6-aza-analogue of Mianserin. Org 3770 and its enantiomers. Neuropharmacology 1988; 2(7)399–408
  • Delini-Stula S., Bischoff A., Mogilnicka E. Rapid changes in functional responsiveness of the 5-HT system after single dose treatment with antidepressants: effects of Maprotiline, Oxaprotiline and its enantiomers. Journal of Psychopharmacology 1986; 3: 7–13
  • Dillen L, Claeys M., Potter W. Z. Effects of the alpha-2 antagonist Idazoxan on monoaminergic parameters measured in the cerebrospinal fluid of rabbits. European Journal of Pharmacology 1987; 13(7)33–40
  • Di-Renzo G., Amoroso S., Tagliatela M., Canzoniero L., Basile V., Fatatis A., Annunziato L. Pharmacological characterisation of serotonin receptors involved in the control of prolactin secretion. European Journal of Pharmacology 1989; 16(2)371–373
  • Doxey J. C., Lane A. C., Roach A. G., Smith C. F.C., Walter D. S. Selective alpha-2 agonists and antagonists. The Pharmacology of Adrenoceptors, E. Szabadi, C. M. Bradshaw, S. R. Nahorski. London, Macmillan 1989; 13–22
  • Dugovic C., Wauquier A., Leysen J. E., Marrannes R., Janssen P. A. Functional role of 5-HT2receptors in the regulation of sleep and wakefulness in the rat. Psychopharmacology 1989; 9(7)436–442
  • Elliott H. L., Jones C. R., Reid J. L. Peripheral pre- and post- junctional alpha-2 adrenoceptors in man: studies with RX 781094 a selective alpha-2 antagonist. Journal of Hypertension (Supplement) 1985; 1: 109–111
  • Risch C. Effect of Fluoxetine on the electrocardiogram. Journal of Clinical Psychiatry 1985; 4(6)42–44
  • Frhaser A., Brown R., Kocsis J., Caroff S., Amsterdam J., Winokur A., Sweeney J., Stokes P. Patterns of melatonin rhythms in depression. Journal of Neural Transmission (Supplement) 1986; 2(1)269–290
  • Freedman J. E., Aghajanian G. K. Idazoxan (RX 781094) selectively antagonises alpha-2 adrenoceptors on rat central neurons. European Journal of Pharmacology 1984; 10(5)265–272
  • Fuller R. W., Perry K. W., Molloy B. B. Effect of an uptake inhibitor on serotonin metabolism in rat brain: studies with Lily 110140. Life Sciences 1974; 1(5)1161–1171
  • Genco S., Puca F. M., Specchio S., Interno L. M., Castriotta R., Leomanni R., Dammacco F. Metergolina e sonno notturno nell' uomo normale. Bollettino — Societa Italiana Biologia Sperimentale (Napoli) 1977; 5(3)1403–1406
  • Ghose K, Sedman E. A double blind comparison of the pharmacodynamic effects of single oral doses of Lofepramine, Amitriptyline and Placebo in elderly subjects. European Journal of Clinical Pharmacology 1983; 33: 505–509
  • Gilbert F., Brazell C., Tricklebank M. D., Stahl S. M. Activation of the 5-HT1areceptor subtype increases rat plasma ACTH concentrations. European Journal of Pharmacology 1988; 14(7)431–439
  • Golden R. N., Markey S. P., Risby E. D., Rudorfer M. V., Cowdry R. W., Potter W. Z. Antidepressants reduce whole blood norepinephrine turnover while enhancing 6-hydroxymelatonin outpatient. Archives of General Psychiatry 1988; 4(5)150–154
  • Goodwin G. M., de Souza R. J., Green A. R. Presynaptic serotonin receptor-mediated response in mice attenuated by antidepressant drugs and electrocon-vulsive shock. Nature 1985; 31(7)531–533
  • Grasby P. M., Begg E. J., Gartside S. E., Cowen P. J. Effect of Idazoxan on evening melatonin plasma concentrations in healthy volunteers. Biological Psychiatry 1989; 2(6)412–416
  • Haase A. F., Greiner H. E., Seyfried C. A. Effects of Lofepramine in biochemical models of antidepressant acitivity. New Therapeutic Developments in Pharmacopsychiatry, H. Friedr. Vieweg Verlagsgesellschaft GbH, Braunschweig 1987; 19–28
  • Harland D, Brown M. J. Effects of acute and chronic administration of Idazoxan on blood pressure and plasma catecholamine concentrations of rats. Journal of Pharmacology and Experimental Therapeutics 1988; 24(5)265–273
  • Hedner T., Pettersson A., Persson B. Chronic 5-HT2receptor blockade by ritanserin does not reduce blood pressure in patients with essential hypertension. Acta Medico Scandinavica 1987; 22(2)307–310
  • Hindmarch I. A pharmacological profile of Fluoxetine and other antidepressants on aspects of skilled performance and car handling ability. British Journal of Psychiatry 1988; 153(Suppl. 3)99–104
  • Hindmarch I., Harrison C., Shillingford C. A. An investigation of the effects of Lofepramine, Nomifensine, Amitriptyline and Placebo on aspects of memory and psychomotor performance related to car driving. International Clinical Psychopharmacology 1986; 3: 157–165
  • Hulten B. A., Heath A. Clinical aspects of tricyclic antidepressant poisoning. Acta Medico. Scandinavica 1983; 21(3)275–278
  • Hwang E., Magnussen I., VanWoert M. H. Effect of chronic Fluvoxamine administration on serotonin administration. Research Cmmunications in Chemical Pathology and Pharmacology 1980; 2(9)79–98
  • Idzikowski C., Cowen P. J., Nutt D., Mills F. J. The effects of chronic ritanserin treatment on sleep and the neuroendocrine response to Tryptophan. Psychopharmacology 1987; 9(3)416–420
  • Idzikowski C., Mills F. J., Glennard R. 5-hydroxytryptamine-2 antagonist increases human slow-wave sleep. Brain Research 1986; 37(8)164–168
  • Jackisch R., Werle E., Hertting G. Identification of mechanisms involved in the modulation of release of noradrenaline in the hippocampus of the rabbit. in vitro, Neuropharmacology 1988; 23: 1363–1371
  • Jann M. W. Buspirone: an update on a unique anxiolytic drug. Phamtacotherapy 1984; 8: 100–116
  • Janssen P. A. The relevence of phamacological studies to sleep research in psychiatry. Pharmacopsychiatry 1988; 2(1)33–37
  • Kerwin Robert W. Monoamine oxidase inhibitors: 30 years of progress. International Review of Psychiatry 1988; 2: 141–147
  • Kennett G. A., Marcou M., Dourish C. T., Curzon G. Single administration of 5-HT1aagonists decreases 5-HT1apresynaptic but not post-synaptic receptor mediated responses: relationship to antidepressant-like actions. European Journal of Pharmacology 1987; 13(8)53–60
  • Kruhlich L., Jurcovicova J., Le T. Prolactin release inhibiting properties of the alpha-2 adrenergic receptor antagonist Idazoxan: comparison with Yohimbine. Life Sciences 1989; 4(4)809–818
  • Lancaster S. G., Gonzalez J. P. Lofepramine: a review of its pharmacodynamic and pharmacokinectic properties and therapeutic efficacy in depressive illness. Drugs 1990; 3(7)123–140
  • Langer S. Z. Presynaptic regulation of the release of catecholamines. Pharmacology Reviews 1981; 3(2)337–362
  • Lapierre Y. D., Rastogi R. B., Singhal R. L. Fluvoxamine influences serotonergic systems in the brain: neurochemical evidence. Neuropsychology 1983; 10: 213–216
  • Lemberger L., Terman S., Rowe H., Billings R. The effect of Nisoxetine a potential antidepressant on biogenic amine uptake in man. British Journal of Clinical Pharmacology, 3: 215–220
  • Leonard B. E. A comparison of the pharmacological properties of the novel tricyclic antidepressant Lofepramine with its major metabolite Desipramine: a review. International Clinical Psychopharmacology 1976; 2: 281–287
  • Leysen J. E., van Gompel P., Gommeren W., Woestenborghs R., Janssen P. A. J. Down-regulation of serotonin-S2 receptor sites in rat brain by chronic treatment with the serotonin-S2 antagonists Ritanserin and Setoperone. Psychopharmacology 1986; 8(8)434–444
  • Maj J., Papp M., Skuza G., Bigajska K., Zazula M. The influence of repeated treatment with Imipramine. (+)- and (−)-Oxaprotiline on behavioural effects of Dopamine D1and D2agonists. Journal of Neural Transmission 1989; 7(7)29–38
  • Martire M., Pistritto G., Preziosi P. Alpha-2 adrenoceptor blocking properties of Idazoxan stereoisomers: stereoselectivity for presynaptic alpha-2 adrenoceptors. Neuroscience Letters 1988; 8(6)328–333
  • Meltzer H. Y., Flemming R., Robertson A. The effect of buspirone on prolactin and growth hormone secretion in man. Archives of General Psychiatry 1983; 40: 1099–2002
  • Mendelson W. B., Jacobs L. S., Reichman J. D., Othmer E., Cryer P. E., Trivedi B., Daughday W. H. Methysergide: suppression of sleep related prolactin secretion and enhancement of sleep related growth hormone secretion. Journal of Clinical Investigation 1975; 5(6)690–697
  • Mogilnicka E., Zazula M., Wedzony K. Functional supersensitivity to the alpha-1 adrenoceptor agonist after repeated treatment with antidepressant drugs is not conditioned by beta down regulation. Neuropharmacology 1987; 2(6)1457–1461
  • Muir N. C, Doxey J. C., Havler M. E., Clifford J. M. The use of ex vivo platelet aggregation to confirm the in vivo alpha-2 adrenoceptor antagonist effect of Idazoxan in man. Journal of Pharmacological Methods 1987; 1(8)95–102
  • Montgomery I., Oswald I., Morgan K., Adam K. Trazodone enhances sleep in subjective quality but not in objective duration. British Journal of Clinical Pharmacology 1983; 1(6)139–144
  • Oswald I., Adam K., Spiegel R. Human slow-wave sleep increased by a serotonin antagonist. Electro-encephalography and Clinical Neurophysiology 1982; 5(4)583–586
  • Palazidou E., Papadopoulos A., Sitsen A., Stahl S., Checkley S. A. An alpha-2 antagonist, Org 3770, enhances nocturnal melatonin secretion in man. Psychopharmacology 1987; 97: 115–117
  • Peroutka S. J., Snyder S. H. Long-term antidepressant treatment decreases spiroperidol-labelled serotonin receptor binding. Science 1980; 210: 88–90
  • Pinder Roger M. The toxicity of antidepressants in overdose: incidence and mechanisms. International Review of Psychiatry 1989; 2: 213–227
  • Plym Forshell G., Siwers B., Tuck J. R. Pharmacokinetics of Lofepramine in man: relationship to inhibition of noradrenaline uptake. European Journal of Clinical Pharmacology 1990; 9: 291–298
  • Preziosi P., Martire M., Navarra P., Pistrttto G., Vacca M. Prolactin lowering ability of (+/−)-Idazoxan may be linked to a central noradrenergic — serotonergic interplay. Journal of Pharmacology and Experimental Therapeutics 1989; 24(9)256–263
  • Price L. H., Charney D. S., Delgado P. L., Anderson G. M., Heninger G. R. Effects of Desipramine and Fluvoxamine treatment on the prolactin response to Tryptophan. Serotonergic function and the mechanism of antidepressant action. Archives of General Psychiatry 1989; 4(6)625–631
  • Raiteri M., Maura G., Versace P. Functional evidence for two stereochemically different alpha-2 adrenoceptors regulating central norepinephrine and serotonin release. Journal of Pharmacology and Experimental Therapeutics 1983; 22(4)679–684
  • Roos J. C. Cardiac effects of antidepressants. A comparison of the tricyclic antidepressants and Fluvoxamine. British Journal of Clinical Pharmacology 1983; 1(5)439–445
  • Sack R. L., Lewy A. J. Desmethylimipramine treatment increases melatonin production in humans. Biological Psychiatry 1985; 2(1)406–409
  • Scheinin H, Virtanen R. Effects of Yohimbine and Idazoxan on monoamine metabolites in rat cerebrospinal fluid. Life Sciences 1986; 3(9)1439–1446
  • Schwabe U., Miyake M., Ohga Y., Daly J. W. 4-3-cyclopentyloxy-4-methoxy-2-pyrrolidone (ZK 62711): a potent inhibitor of adenosine cyclic 3′, 5′-monophosphate phosphodiesterases in homogenates and tissue slices from rat brain. Molecular Pharmacology 1976; 12: 900–910
  • Segawa T., Nomura Y., Tanaka A., Murakami H. Effect of Lofepramine and other antidepressants on the uptake of 5-hydroxytryptamine and noradrenaline into rat brain monoammergic neurons. Journal of Pharmacy and Pharmacology 1977; 2(9)139–142
  • Shur E, Checkley S. A. Pupil studies in depressed patients; an investigation of the mechanisms of action of Desipramine. British Journal of Psychiatry 1982; 140: 181–184
  • Siwers B., Borg S., D'Elia G., Lundin G., Plym Forschell G., Raotma M., Roman G. Comparative clinical evaluation of Lofepramine and Imipramine: pharmacological aspects. Acta Psychiatrica Scandinavica 1977; 5(5)21–31
  • Sjogren C. The pharmacological profile of Lofepramine, a new antidepressant drug. Neuropharmacology 1976; 19: 1213–1214
  • Starke K. Presynaptic receptors and the control of noradrenaline release. Trends in Pharmacological Sciences 1980; 6: 268–271
  • Stephenson J. D. Neuropharmacological studies of the serotonergic system. International Review of Psychiatry 1980; 2: 165–185
  • Stern H., Konetschny J., Herrmann L., Sawe U., Belz G. G. Cardiovascular effects of single doses, of the antidepressants Amitriptyline and Lofepramine in healthy subjects. Pharmacopsychiatry 1990; 78: 272–277
  • Struthers A. D., Burrin J. M., Brown M. J. Exercise induced increases in plasma catecholamines and growth hormone are augmented by selective alpha-2 adrenoceptor blockade in man. Neuroendocrinology 1986; 4(4)22–28
  • Sulser F. Regulation and function of noradrenaline receptor systems in brain. Psychopharmacological aspects. Neuropharmacology 1984; 2(3)255–261
  • Szabadi E., Gasner P., Bradshaw C. M. The peripheral anticholinergic activity of tricyclic antidepressants: comparison of Amitriptyline and Desipramine in human volunteers. British Journal of Psychiatry 1980; 13(7)433–439
  • Thompson C, Checkley S. A. The effects of a allaproclate on the pupillary responses to tyramine, Phenylephrine and Pilocarpine in depressed patients. Psychopharmacology 1985; 85: 65–68
  • Thompson C., Mezey G., Corn T., Franey C., English J., Arendt J., Checkley S. A. The effect of Desipramine upon melatonin and cortisol secretion in depressed and normal subjects. British Journal of Psychiatry 1985; 14(7)389–393
  • Tormey W. P., Buckley M. P., O'Kelly D. A., Conboy J., Finder R. M., Darragh M. D. Sleep-endocrine profile of the antidepressant Mianserin. Current Medical Research Opinion 1985; 6: 456–460
  • U'Prichard D. C., Bechtel W. D., Rouot B. R., Snyder S. H. Multiple apparent a-noradrenergic receptor binding sites in rat brain: effect of 6-OH Dopamine. Molecular Pharmacology 1979; 1(6)47–60
  • Waldmeier P. C., Baumann P. A., Wilhelm M., Bernasconi R., Maitre L. Selective inhibition of noradrenaline and serotonin uptake by C 49802 B- and CGP 6985A. European Journal of Pharmacology 1977; 4(6)387–391
  • Washburn M, Moises H. C. Electrophysiological correlates of presynaptic alpha-2 receptor mediated inhibitors of norepinephrine release at locus coeruleus synapses in dentate gyrus. The Journal of Neuroscience 1980; 9: 2131–2140
  • Wood K., Swade C., Abou-saleh M., Milln P., Coppen A. Drug plasma levels and platelet 5-HT uptake inhibition during long term treatment with Fluvoxamine or Lithium in patients with affective disorders. British Journal of Clinical Pharmacology 1983; 15(Suppl. 3)365–368

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