The neuropathology of HIV: a review of the first 10 years

References

• Aherne W. A., Dunnill M. S. Morphometry. Edward Arnold, London 1982
   Google Scholar
• Anders K. H., Guerra W. F., Tomiyasu U., Verity M. A., Vinter H. V. The neuropathology of AIDS: UCLA experience and review. American Journal of Pathology 1986; 124: 537–558
   PubMed Web of Science ®Google Scholar
• Brenneman D. E., Westbrook G. L., Fitzgerald S. P., et al. Neuronal cell killing by the envelope protein and its prevention by vasoactive peptide. Nature 1988; 335: 639–642
   PubMed Web of Science ®Google Scholar
• Britton C. B., Miller J. R. Neurologic complications in acquired immunodeficiency syndrome (AIDS). Neurologic Clinics 1984; 2: 315–339
   PubMed Web of Science ®Google Scholar
• Budka H. Human immunodeficiency virus (HIV)-induced disease of the central nervous system: pathology and implications for pathogenesis. Acta Neu-ropathologica 1990; 77: 225–236
   Google Scholar
• Budka H. Neuropathology of human immunodeficiency virus infection. Brain Pathology 1991; 1: 163–175
   PubMed Web of Science ®Google Scholar
• Budka H., Costanzi G., Cristina S., et al. Brain pathology induced by infection with human immunodeficiency virus (HIV). A histological, immunocytoche-mical, and electron microscopical study of 100 autopsy cases. Acta Neuropathologica 1987; 75: 185–198
   PubMed Web of Science ®Google Scholar
• Budka H., Wiley C. A., Kleihues P., et al. HIV-associated disease of the nervous system and proposal for neuropathology-based terminology. Brain Pathology 1991; 1: 143–152
   PubMed Web of Science ®Google Scholar
• Catalan J. Psychiatric manifestations in HIV disease. Balliere's Clinical Gastroenterology 1990; 4: 547–562
   PubMed Web of Science ®Google Scholar
• Center for Disease Control. Pneumocystis pneumonia—Los Angeles. Morbidity and Mortality Weekly Report 1981a; 30: 250–252, 5 June
   PubMedGoogle Scholar
• Center for Disease Control. Kaposi's sarcoma and pneumocystis pneumonia among homosexual men—New York City and California. Morbidity and Mortality Weekly Report 1981b; 30: 305–308, 3 July
   PubMedGoogle Scholar
• Center for Disease Control. Revision of the CDC surveillance case definition for acquired immunodeficiency syndrome. Morbidity and Mortality Weekly Report 1987; 36: 3S–14S, 14 August
   Google Scholar
• Cheng-Mayer C. Biological and molecular features of HIV-1 related to ti tropism. AIDS 1990; 4: S49–S56
   Google Scholar
• Cheng-Mayer C., Levy J. A. Distinct biological and serological properties of human immuno-deficiency viruses from the brain. Annals of Neurology 1988; 23: S58–S61
   Web of Science ®Google Scholar
• Cordonnier A., Montagnier L., Emerman M. Single amino-acid changes in HIV envelope affect viral tropism and receptor binding. Nature 1989; 340: 571–574
   PubMed Web of Science ®Google Scholar
• Deicken R. F., Hubesch B., Jensen P. C., et al. Alterations in brain phosphate metabolite concentrations in patients with human immunodeficiency virus infection. Archives of Neurology 1991; 48: 203–209
   PubMedGoogle Scholar
• De La Monte S. M., Ho D. D., Schooley R. T., Hirsch M. S., Richardson E. P. Subacute encephalomyelitis of AIDS and its relation to HTLV-III infection. Neurology 1987; 37: 562–569
   PubMed Web of Science ®Google Scholar
• Dix R. D., Waitzman D. M., Follansbee S., et al. Herpes simplex virus type 2 encephalitis in two homosexual men with persistent lymphadenopathy. Annals of Neurology 1985; 17: 203–206
   PubMedGoogle Scholar
• Dreyer E. B., Kaiser P. K., Offermann J. T., Lipton S. A. HIV-1 coat protein neurotoxocity prevented by calcium channel antagonists. Science 1990; 248: 364–367
   PubMed Web of Science ®Google Scholar
• Elovaara I., Poutianen E., Raininko R., et al. Mild brain atrophy in early HIV infection: the lack of association with cognitive deficits and HIV-specific intrathecal immune response. Journal of the Neurological Sciences 1990; 99: 121–136
   PubMed Web of Science ®Google Scholar
• Epstein L. G., Sharer L. R., Cho E. S., Meyenhofer M. F., Navia B. A., Price R. W. HTLV III/LAV-like retrovirus particles in the brains of patients with AIDS encephalopathy. AIDS Research 1985; 1: 447–454
   Google Scholar
• Esiri M. M., Scaravilu F., Millard P. R., Har-Court-Webster J. N. Neuropathology of HIV infection in haemophiliacs: comparative necropsy study. British Medical Journal 1990; 299: 1312–1315
   Google Scholar
• Everall I. P., Luthert P. J., Lantos P. L. Neuronal loss in the frontal cortex in HIV infection. The Lancet 1991a; 337: 1119–1121
   PubMed Web of Science ®Google Scholar
• Everall I. P., Luthert P. J., Lantos P. L. Cell population changes in the putamen and frontal cortex in HIV infection. Neuropathology and Applied Neurobiology 1991b; 17: 246
   Google Scholar
• Gartner S., Markovitz P., Markovitz D. M. The role of mononuclear phagocytes in HTLV III/LAV infection. Science 1986; 234: 1563–1566
   PubMedGoogle Scholar
• Giulian D., Vaca K., Noonan C. A. Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1. Science 1990; 250: 1593–1596
   PubMed Web of Science ®Google Scholar
• Gray F., Gherardi R., Keohane C., Favolini M., Sobels A., Poirler J. Pathology of the central nervous system in 40 cases of acquired immune deficiency syndrome (AIDS). Neuropathlogy and Applied Neurobiology 1988a; 14: 365–380
   PubMedGoogle Scholar
• Gray F., Gherardi R., Scaravilli F. The neuropathology of the acquired immune deficiency syndrome (AIDS). Brain 1988b; 111: 245–266
   PubMed Web of Science ®Google Scholar
• Gray F., Gherardi R., Lescs M. C., et al. Early brain changes in HIV infection: neuropathologic study of 11 HIV-seropositive, non AIDS asymptomatic cases, Neuroscience of HIV infection Basic and Clinical Frontiers. Satellite Conference to the VII International Conference on AIDS, PadovaItaly, June, 12–151991, 35
   Google Scholar
• Grimaldi L. M. E., Martino G. V., Franciotta D. M., et al. Elevated alpha-tumor necrosis factor levels in spinal fluid from HIV-1 infected patients with central nervous system involvement. Annals of Neurology 1991; 29: 21–25
   PubMed Web of Science ®Google Scholar
• Hamilton-Dutoit S. J., Pallesen G., Franzmann M. B., et al. AIDS-related lymphoma. Histology, immunophenotype, and association with Epstein-Barr virus as demonstrated by in situ nucleic acid hybridisation. American Journal of Pathology 1991; 138: 149–163
   PubMed Web of Science ®Google Scholar
• Harouse J. M., Wroblewska Z., Laughlin M. A., Schonwetter B. S., Gonzalez-Scarano F. Human choroid plexus cells can be latently infected with human immunodeficiency virus. Annals of Neurology 1989; 4: 406–411
   Google Scholar
• Haug H. History of neuromorphometry. Journal of Neuroscience Methods 1986; 18: 1–17
   PubMedGoogle Scholar
• Heyes M. P., Brew B. J., Martin A., et al. Quinolinic acid in cerebrospinal fluid and serum in HIV-1 infection: relationship to clinical and neurological status. Annals of Neurology 1991; 29: 202–209
   PubMed Web of Science ®Google Scholar
• Ho D. D., Rota T. R., Schooley R. T., et al. Isolation of HTLV-III from cerebrospinal fluid and neural tis of patients with neurologic syndromes related to the acquired immunodeficiency syndrome. New England Journal of Medicine 1985; 313: 1493–1497
   PubMed Web of Science ®Google Scholar
• Horten B., Price R. W., Jimenez D. Multifocal varicella-zoster virus leukoencephalitis temporally remote from herpes zoster. Annals of Neurology 1981; 9: 251–266
   PubMed Web of Science ®Google Scholar
• Janssen R. S., Saykin A. J., Cannon L., et al. Neurological and neuropsychological manifestations of HIV-1 infection: association with AIDS-related complex but not asymptomatic HIV-1 infection. Annals of Neurology 1989; 26: 592–600
   PubMed Web of Science ®Google Scholar
• Kaiser P. K., Offermann J. T., Lipton S. A. Neuronal injury due to HIV-1 is blocked by anti-gpl20 antibodies but not by anti-CD4 antibodies. Neurology 1990; 40: 1757–1761
   PubMed Web of Science ®Google Scholar
• Kaus J., Zurlinden B., Schlote W. Asonal volume and myelin sheath thickness of central nervous system myelinated fibres are reduced in HIV-encephal-opathy. Clinical Neuropathology 1991; 10: 38
   Google Scholar
• Keating J. N., Trimble K. C., Mulchay F., Scott J. M., Weir D. G. Evidence of brain methyl-transferase inhibition and early brain involvement in HIV-positive patients. Lancet 1991; 337: 935–939
   PubMed Web of Science ®Google Scholar
• Ketzler S., Weis S., Haug H., Budka H. Loss of neurons in the frontal cortex in AIDS brains. Acta Neuropathologica 1990; 80: 92–94
   PubMed Web of Science ®Google Scholar
• Kimes A. S., London E. D., Szabo G., Raymon L., Tabakoff B. Reduction of cerebral glucose utilisation by the HIV envelope glycoprotein gpl20. Experimental Neurology 1991; 112: 224–228
   PubMedGoogle Scholar
• Kleihues P., Lang W., Burger P. C., et al. Progressive diffuse leukoencephalopathy in patients with acquired immune deficiency syndrome. Journal of Neuropathology and Experimental Neurology 1985; 50: 171–183
   Google Scholar
• Lantos P. L., McLaughlin J. E., Scholtz C. L., Berry C. L., Tighe J. R. Neuropathology of the brain in HIV infection. Lancet 1989; 1: 309–311
   PubMedGoogle Scholar
• Laurence J. Molecular interactions among herpes viruses and human immunodeficiency viruses. Journal of Infectious Diseases 1990; 162: 338–346
   PubMed Web of Science ®Google Scholar
• Lenhardt T. M., Super M. A., Wiley C. A. Neuropathological changes in an asymptomatic HIV seropositive man. Annals of Neurology 1988; 23: 209–210
   PubMedGoogle Scholar
• Levy J. A. Changing concepts in HIV infection: challenges for the 1990s. AIDS 1990; 4: 1051–1058
   PubMedGoogle Scholar
• Levy R. M., Bredesen D. E., Rosenblum M. L. Neurological manifestations of the acquired immunodeficiency syndrome (AIDS): experience at UCSF and review of the literature. Journal of Neuro-surgery 1985; 62: 475–495
   Google Scholar
• Levy R. M., Jansen R. S., Bush R. J., Rosenblum M. L. Neuroepidemiology of the acquired immunodeficiency syndrome. AIDS and the Nervous System, M. L. Rosenblum, R. M. Levy, D. E. Bredesen. Raven Press, New York 1988; 13–27
   Google Scholar
• Lipton S. A. HIV-related neurotoxicity. Brain Pathology 1991; 1: 193–199
   PubMed Web of Science ®Google Scholar
• Lipton S. A., Sucher N. J., Kaiser P. K., Dreyer E. B. Synergistic effects of HIV coat protein and NMDA receptor-mediated neurotoxocity. Neuron 1991; 7: 111–118
   PubMed Web of Science ®Google Scholar
• Locksley R. M., Crowe S., Saddick M. D., et al. Release of interleukin I inhibitory activity (contra IL-1) by human monocyte derived macrophages infected with human immunodeficiency virus in vitro and in vivo. Journal of Clinical Investigation 1988; 82: 2097–2105
   PubMedGoogle Scholar
• Lusso P., Ensoli B., Markham P. D., et al. Productive dual infection of human CD4 + T lymphocytes by HIV-1 and HHV-6. Nature 1989; 337: 370–373
   PubMed Web of Science ®Google Scholar
• Manji H., McAllister R., Connolly S., et al. A longitudinal study of the clinical neurological complications of HIV infection—the Middlesex/Medical Research Council cohort study. Neuroscience of HIV Infection Basic and Clinical Frontiers Conference, PadovaItaly, June, 12–151991, 46
   Google Scholar
• McAllister R. H., Herns M. V., Harrison M. J. G., et al. Neurological and neurophysiological performance in HIV seropositive asymptomatic individuals. Journal of Neurology, Neurosurgery, and Psychiatry 1991, in press
   Google Scholar
• McArthur J. C., Cohen B. A., Selnes O. A., et al. Low prevalence of neurological and neuropsy-chological abnormalities in otherwise healthy HIV-1 infected individuals: results from the multicenter AIDS cohort study. Annals of Neurology 1989; 26: 601–611
   PubMed Web of Science ®Google Scholar
• Meltzer M. S., Nakamura M., Hansen B. D., Turpin J. A., Kalter D. C., Gendelman H. E. Macrophages as susceptible targets for HIV infection, persistent viral reservoirs in ti and key immunore-gulatory cells that control levels of virus replication and extent of disease. AIDS Research and Human Retrovi-ruses 1990; 6: 967–971
   PubMed Web of Science ®Google Scholar
• Michaels J., Sharer L. R., Epstein L. G. Human immunodeficiency virus type 1 (HIV-1) infection of the nervous system: a review. Immunodeficiency Reviews 1988; 1: 71–104
   PubMedGoogle Scholar
• Moeller A. A., Backmund H. C. Ventricle and brain ratio in the clinical course of HIV infection. Acta Neurologica Scandinavia 1990; 81: 512–515
   PubMedGoogle Scholar
• Montagnier L. HIV pathogensis. VI International Conference on AIDS, Final Program and Abstracts, San FranciscoUSA, 1990; 1: 150
   Google Scholar
• Mullins J. I., Chen C. S., Hoover E. A. Disease-specific and ti-specific production of unin-tegrated feline leukaemia virus variant DNA in feline AIDS. Nature 1986; 319: 333–336
   PubMed Web of Science ®Google Scholar
• Navia B. A., Jordan B. D., Price R. W. The AIDS dementia complex I. Clinical features. Annals of Neurology 1986a; 19: 517–524
   PubMed Web of Science ®Google Scholar
• Navia B. A., Cho E. S., Petito C. K., Price R. W. The AIDS dementia complex II. Neuropatho-logy. Annals of Neurology 1986b; 19: 525–535
   PubMed Web of Science ®Google Scholar
• Navia B. A., Petito C. K., Gold J. W. M., Cho E. S., Jordan B. D., Price R. W. Cerebral toxoplasmosis complicating the acquired immune deficiency syndrome: clinical and neuropathological findings in 27 patients. Annals of Neurology 1986c; 19: 224–238
   PubMed Web of Science ®Google Scholar
• Nielsen S. L., Davis R. L. Neuropathology of acquired immunodeficiency syndrome. AIDS and the Nervous System, M. L. Rosenblum, R. M. Levy, D. E. Bredesen. Raven Press, New York 1988; 155–181
   Google Scholar
• O'Brien W. A., Zack J. A., Chen I. S. Y. Molecular pathogenesis of HIV-1. AIDS 1990; 4: S41–S48
   PubMedGoogle Scholar
• Osborn L., Kunkel S., Nabel G. J. Tumour necrosis factor α and interleukin 1 stimulate the human immunodeficiency enhancer by activation of nuclear factor kB. Proceedings of the National Academy of Sciences, USA 1989; 86: 2336–2340
   PubMed Web of Science ®Google Scholar
• Pang S., Koyangi Y., Miles S., Wiley C., Vinters H., Chen I. S. Y. High levels of unintegrated HIV-1 DNA in brain ti of AIDS dementia patients. Nature 1990; 343: 85–89
   PubMed Web of Science ®Google Scholar
• Peluso R., Haase A., Stowing L., Edwards M., Ventura P. A Trojan Horse mechanism for the spread of visna virus in monocytes. Virology 1985; 147: 231–236
   PubMed Web of Science ®Google Scholar
• Petito C. K., Navia B. A., Cho E. S., Jordan B. D., George D. C., Price R. W. Vacuolar myelopathy pathologically resembling subacute combined degeneration in patients with the acquired immunodeficiency syndrome. New England Journal of Medicine 1985; 312: 874–879
   PubMed Web of Science ®Google Scholar
• Petito C. K., Cho E. S., Lemann W., Navia B. A., Price R. W. Neuropathology of acquired immunodeficiency syndrome (AIDS): an autopsy review. Journal of Neuropathology and Experimental Neurology 1986; 45: 653–646
   Google Scholar
• Price R. W., Brew B., Sidtis J., Rosenblum M., Scheck A. C., Cleary P. The brain in AIDS: central nervous system HIV-1 infection and AIDS dementia complex. Science 1988; 239: 586–592
   PubMed Web of Science ®Google Scholar
• Price R. W., Sidtis J. J., Brew B. AIDS dementia complex and HIV-1 infection: a view from the clinic. Brain Pathology 1991; 1: 155–162
   PubMed Web of Science ®Google Scholar
• Pulliam L., Herndier B. G., Tang N. M., McGrath M. S. Human immunodeficiency virus-infected macrophages produce soluble factors that cause histological and neurochemical alterations in cultured human brains. Journal of Clinical Investigation 1991; 87: 503–512
   PubMedGoogle Scholar
• Pumarola-Sune T., Navia B. A., Cordon-Cardo C., Cho E. S., Price R. W. HIV antigen in the brains of patients with the AIDS dementia complex. Annals of Neurology 1987; 21: 490–496
   PubMed Web of Science ®Google Scholar
• Rottenberg D. A., Moeller J. R., Strother S. C., et al. The metabolic pathology of the AIDS dementia complex. Annals of Neurology 1987; 22: 700–706
   PubMed Web of Science ®Google Scholar
• Selmaj K. W., Raine C. S. Tumour necrosis factor mediates myelin and oligodendrocytes damage in vitro. Annals of Neurology 1988; 23: 339–346
   PubMed Web of Science ®Google Scholar
• Shaw G. M., Harper M. E., Hahn B. H., et al. HTLV-III infection in the brains of children and adults with AIDS encephalpathy. Science 1985; 227: 177–182
   PubMed Web of Science ®Google Scholar
• Smith T. W., Degirolami U., Henin D., Bolgert F., Hauw J.-J. Human immunodeficiency virus (HIV) leukoencephalopathy and the microcirculation. Journal of Neuropathology and Experimental Neurology 1990; 49: 357–370
   PubMed Web of Science ®Google Scholar
• Snider W. D., Simpson D. M., Nielsen S., Gold J. W. M., Metroka C. E., Posner J. B. Neurological complications of acquired immune deficiency syndrome: analysis of 50 patients. Annals of Neurology 1983; 14: 403–418
   PubMed Web of Science ®Google Scholar
• Sterio D. C. The unbiased estimation of number and sizes of arbitrary particles using the disector. Journal of Microscopy 1984; 134: 127–136
   PubMed Web of Science ®Google Scholar
• Stoler M. H., Eskin T. A., Benn S., Angerer R. C., Angerer L. M. Human T-cell lymphotropic virus type III infection of the central nervous system. A preliminary in situ analysis. Journal of the American Medical Association 1986; 256: 2381–2383
   Google Scholar
• Taruscio D., Malchiodi Abedi F., Bagnato R., et al. Increased reactivity of laminin in the basement membranes of capillary walls in AIDS brain cortex. Acta Neuropathologica 1991; 81: 552–556
   PubMedGoogle Scholar
• Tucker T., Dix R. D., Katzen C., Davis R. L., Schmidley J. W. Cytomegalovirus and herpes simplex virus ascending myelitis in a patient with acquired immune deficiency syndrome. Annals of Neurology 1985; 18: 74–79
   PubMed Web of Science ®Google Scholar
• Vazeux R., Cumont M., Girard P. M., et al. Severe encephalitis resulting from coinfections with HIV and JC virus. Neurology 1990; 40: 944–948
   PubMedGoogle Scholar
• Vinters H. V., Anders K. H. Neuropathology of AIDS. CRC Press, Florida 1990
   Google Scholar
• Vinters H. V., Kwok M. K., Ho H. W., et al. Cytomegalovirus in the nervous system of patients with the acquired immune deficiency syndrome (AIDS). Brain 1989; 112: 245–268
   PubMed Web of Science ®Google Scholar
• Wahl L. M., Corcoran M. L., Pyle S. W., Arthur L. O., Harel-Bellan A., Farrar W. L. Human Immunodeficiency virus glycoprotein (gpl20) induction of monocyte arachidonic acid metabolites and interleukin 1. Proceedings of the National Academy of Sciences, USA 1989; 86: 621–625
   PubMed Web of Science ®Google Scholar
• Walker D. G., Itagaki S., Berry K., McGeer P. L. Examination of brains of AIDS cases for human immunodeficiency virus and cytomegalovirus nucleic acids. Journal of Neurology, Neurosurgery, and Psychiatry 1989; 52: 583–590
   PubMedGoogle Scholar
• Wiley C. A., Schrier R. D., Nelson J. A., Lampert P. W., Oldstone M. B. A. Cellular localisation of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients. Proceedings of the National Academy of Sciences, USA 1986; 83: 7089–7093
   PubMed Web of Science ®Google Scholar
• Wiley C. A., Masliah E., Morey M., et al. Neocortical damage during HIV infection. Annals of Neurology 1991; 29: 651–657
   PubMed Web of Science ®Google Scholar