Behavioral pharmacology of serotonin receptor subtypes: hypotheses for clinical applications of selective serotonin ligands

References

• Agren H., Mefford I., Rudorfer M., et al. Interacting neurotransmitter systems: a non-experimental approach to the 5HIAAHVA correlation in human CSF. Journal of Psychiatric Research 1986; 20: 175–193
   PubMed Web of Science ®Google Scholar
• Badaway A.A.B., et al. Tryptophan and 5-HT metabolism in alcoholism. Alcohol and Alcoholism 1993, Suppl 2: 231–235
   Google Scholar
• Badeway A., Evans M. Opposite effects of chronic administration and subsequent withdrawal of drugs of dependence on the metabolism of endogeneous and exogeneous tryptophane in the rat. Alcohol and Alcoholism 1983; 18: 369–382
   Google Scholar
• Baldessarini R.J., Frankenburg F.R. Clozapine: A Novel antipsychotic agent. New England Journal of Medicine 1991; 324(11)746–754
   PubMed Web of Science ®Google Scholar
• Barret J.E., Vanover K.E. 5-HT receptors as targets for the development of novel anxiolytic drugs: models, mechanisms and future directions. Psychopharmacology 1993; 112: 112
   Google Scholar
• Bielenberg G.W., Burkhardt M. 5-HTA agonists, a new therapeutic principle for stroke treatment. Stroke 1990; 21(suppl IV)161–163
   Google Scholar
• Blanchard R.J., Fukunaga D.C., Blanchard D.C., et al. Nonspecific aggression in the aboratory rat. Journal of Comparative Physiological Psychology 1975; 89: 1204–1209
   PubMed Web of Science ®Google Scholar
• Blanchard R.J., Blanchard D.C. Attack and defence in rodents as ethoexperimental models for the study of emotion. Progress in Neuro-Psychopharmacology and Biological Psychiatry 1989; 13: S3–S14
   Web of Science ®Google Scholar
• Bleich A., Brown S., Kahn R.S., van Praag H.M. The role of serotonin in schizophrenia. Schizophrenia Bulletin 1988; 14: 297–315
   PubMedGoogle Scholar
• Bode Greuel K.M., Kirsch J., Horvath E., Glaser T., Traber J. Effects of 5-HTA receptor agonists on hippocampal damage after transient forebrain ischemia in the mongolian gerbil. Stroke 1990; 21(Suppl IV)164–166
   Google Scholar
• Brown G.L., Ebert M.H., Goyer P.F., et al. Aggression, suicide, and serotonin; relationships to csf amine metabolites. American Journal of Psychiatry 1982; 139: 741–746
   PubMed Web of Science ®Google Scholar
• Coccaro E.F., Murphy D.L. Clinical Significance of central serotonergic system dysfunction in major psychiatric disorders. Serotonin in Major Psychiatric Disorders. American Psychiatric Press, Washington, DC 1990
   Google Scholar
• Coccaro E.F., Sever L.J., Klar H.M., et al. Serotonergic studies in patients with affective and personality disorders: correlates with suicidal and impulsive aggressive behavior. Archives of General Psychiatry 1989; 46: 587–599
   PubMed Web of Science ®Google Scholar
• Coccaro E.F., Kavoussi R.J., Lesser J.C. Self and otherdirected human aggression: the role of the central serotonergic system. International Clinical Psychopharmacology 1992; 6(suppl 6)70–83
   PubMed Web of Science ®Google Scholar
• Compagnon P., et al. Serotonin in animal models of alcoholism. Alcohol and Alcoholism 1993, Suppl 2: 215–219
   Google Scholar
• Cook E.H., Perry B.D., Dawson G., et al. Receptor inhibition by immunoglobulins: specific inhibition by autistic children, their relatives, and control subjects. Journal of Autism and Developmental Disorders 1993; 23: 67–78
   PubMedGoogle Scholar
• Cornelius J.R., Soloff P.H., Perel J.M., Ulrich R.F. Fluoxetine: trial in borderline personality disorder. Psychopharmacology Bulletin 1990; 26: 151–154
   PubMedGoogle Scholar
• Cornelius J.R., Soloff P.H., Perel J.M., Ulrich R.F. Continuation therapy of borderline personality disorder with haloperidol and phenelzine. American Journal of Psychiatry 1993; 150: 1843–1848
   PubMed Web of Science ®Google Scholar
• Costall B., Naylor R.J., Tyers M.B. The psychopharmacology of 5-HT3 receptors. Pharmacological Therapies 1990; 47: 181–202
   PubMed Web of Science ®Google Scholar
• Davidson K.M., et al. The relationship between alcohol dependence and depression. Alcohol and Alcoholism 1993; 28: 147–155
   PubMed Web of Science ®Google Scholar
• Demchyshyn L., Sunahara R.K., Miller K., et al. A human serotonin ID receptor variant. Proceedings of the National Academy of Sciences 1992; 89: 5522–5526
   PubMed Web of Science ®Google Scholar
• De Vry J., Schreiber R., Glaser T., Traber J. Behavioral pharmacology of 5-HTIA agonists: animal models of anxiety and depression. Serotonin 1A receptors in depression and anxiety, S.M. Stahl, M. Gastpar, Hesselink Keppel, J. Traber. Raven Press, New York 1992
   Google Scholar
• Dillon K.A., et al. Autographic analysis of serotonin 5-HTIA receptor binding in the human brain postmortem: effects of age and alcohol. Brain Research 1991; 554: 56–64
   PubMed Web of Science ®Google Scholar
• Eison A.S., Yocca F.D. Reduction in cortical 5-HT2 receptor sensitivity after continuous gepirone treatment. European Journal of Pharmacology 1985; 111: 389–392
   Google Scholar
• Fahy T.A., Eisler I., Russel G.F. A placebo-controlled trial of d-fenfluramine in bulimia nervosa. British Journal of Psychiatry 1993; 162: 597–603
   PubMed Web of Science ®Google Scholar
• Gaddum J.H., Picarelli Z.P. Two different kinds of tryptamine receptor. British Journal of Pharmacology 1957; 12: 323–328
   PubMed Web of Science ®Google Scholar
• Garattini S., Bizzi A., Caccia S., et al. Progress in assessing the role of serotonin in the control of food intake. Clinical Neuropharmacology 1988; 11(Suppl 1)S832
   Google Scholar
• Goldberg S.C., Schulz S.C., Schulz P.M., et al. Borderline an schizotypal personality disorder treated with low dose thioxene vs placebo. Archives of General Psychiatry 1988; 43: 680–686
   Google Scholar
• Goyer P.F., Andreason P.J., Semple W.E., et al. Positron emission tomography and personality disorders. Neuropsychopharmacology 1994; 10: 21–28
   PubMed Web of Science ®Google Scholar
• Grignaschi G., Mantelu B., Samanin R. The hypophagic effect of restraint stress in rats can be mediated by 5-HT2 receptors in the paraventricular nucleus of the hypothalamus. Neuroscience Letters 1993; 152: 1036
   Google Scholar
• Gudelsky G.A. Dopaminergic and serotonergic effects of clozapine. Drug Research 1992; 42: 268–272
   Google Scholar
• Gudelsky G.A., Meltzer H.Y. Activation of tuberoinfundibular dopamine neurons following acute administration of atypical neuroleptics. Neuropsychopharmacology 1989; 2: 45–51
   Google Scholar
• Halliday G., Ellis J., Heard R., Caine D., Harper C. Brainstem serotonergic neurons in chronic alcoholics with and without the memory impairment of Korsakoff's psychosis. Journal of Neuropathology and Experimental Neurology 1993; 52: 567–579
   PubMed Web of Science ®Google Scholar
• Hamon M., Fattaccini C.M., Adrien J., et al. Alteration of central serotonin and dopamine turnover in rats treated with ipsapirone and other 5-HTIA agonists with potential anxiolytic properties. Journal of Pharmacology and Experimental Therapeutics 1988; 246: 745–752
   Google Scholar
• Hoch P.H., Cattell J.P., Pennes H.H. Effects of mescaline and lysergic acid. American Journal of Psychiatry 1952; 108: 579–584
   PubMed Web of Science ®Google Scholar
• Hull J.W., Clarkin J.F., Alexopoulos G.S. Time series analysis of intervention effects. Fluoxetine therapy as a case illustration. Journal of Nervous and Mental Disease 1993; 181: 48–53
   Google Scholar
• Hutson P.H., Dourish C.T., Curzon G. Neurochemical and behavioural evidence for mediation of the hyperphagic action of 80HDPAT by 5-HT cell body autoreceptors. European Journal of Pharmacology 1986; 129: 347–352
   PubMedGoogle Scholar
• Hutson P.H., Dourish C.T., Curzon G. Evidence that the hyperphagic response to 80HDPAT is mediated by 5-HTIA receptors. European Journal of Pharmacology 1988; 150: 361–366
   PubMed Web of Science ®Google Scholar
• Jimerson D.C., Lesem M.D., Kaye W.H., et al. Eating disorders and depression: is there a serotonin connection?. Biological Psychiatry 1990; 28: 443–454
   Google Scholar
• Jimerson D.C., Lesem M.D., Kaye W.H., Brewerton T.D. Low serotonin and dopamine metabolite concentrations in cerebrospinal fluid from bulimic patients with frequent binge episodes. Archives of General Psychiatry 1992; 49: 13–28
   Google Scholar
• Kahn R.S., Davidson M. Serotonin receptor responsivity in schizophrenia. International Clinical Psychopharmacology 1993; 8(supplement 2)47–51
   Google Scholar
• Kaye W.H., Weltztn T.E. Serotonin activity in anorexia and bulimia nervosa: relationship to the modulation of feeding and mood. Journal of Clinical Psychiatry 1991; 52: 418, Suppl
   Google Scholar
• Leibowitz S.F. The role of serotonin in earing disorders. Drugs 1990; 39(Suppl 3)33–48
   PubMed Web of Science ®Google Scholar
• Leonard M.B. Serotonin receptors where are they going?. International Clinical Psychopharmacology 1994; 9(suppl. 1)717
   Google Scholar
• Lesch K.P., Aulakh C.S., Murphy D.L. Serotonin receptor heterogeneity and subsystem complexity: implications for clinical neuropsychopharmacology. Neurology and Psychiatric Brain Research 1993; 1: 163–172
   Google Scholar
• Linnoila V.M.I., Virkkunen M. Aggression, suicidality, and serotonin. Journal of Clinical Psychiatry 1993; 53(suppl 10)46–51
   Google Scholar
• Littrell J. Understanding and treating. Alcoholism, Vol 2: biological, psychological and social aspects of alcohol consumption and abuse. Lawrence, New Jersey 1991
   Google Scholar
• Lovenberg T.W., Erlander M.G., Baron B.M., Sutcliffe J.G. Cloning of new 5-HT receptors. International Clinical Psychopharmacology 1993; 8(Suppl 2)19–23
   Google Scholar
• Lucki I., Singh A., Kreiss D.S. Antide-pressandike behavioral effects of serotonin receptor agonists. Neuroscience and Biobehavioral Reviews 1994; 18: 85–95
   PubMed Web of Science ®Google Scholar
• McBride J., et al. Serotonin, dopamine, and GABA involvement in alcohol drinking of selectively bred rats. Alcohol 1990; 7: 199–205
   Google Scholar
• Manier D.H., Gillespie D.D., Sanders-Bush E., et al. The serotonin/noradrenaline link in the brain. Nauyn Schmiedebergs Archives of Pharmacology 1987; 335: 109–114
   Google Scholar
• Markovttz P.J., Calabrese J.R., Schulz S.C., Melzer H.Y. Fluoxetine in die treatment of borderline and schizotypal personality disorder. American Journal of Psychiatry 1991; 148: 1064–1067
   Google Scholar
• Massi M., Marini S. Effect of the 5-HT2 antagonist ritanserin on food intake and on 5-H induced anorexia in the rat. Pharmacology and Biochemistry Behavior 1987; 26: 333–340
   Google Scholar
• Meltzer H.Y. Studies of odansetron in schizophrenia. The Role of Odansetron, a Novel 5-HT₃ Antagonist in the Treatment of Psychiatric Disorders: 5th World Congress of Biological Psychiatry. Gardiner Caldwell Communications Limited, Florence 1991
   Google Scholar
• Mita T., Hanada S., Nishino N., et al. Decreased serotonin S2 and increased D2 in chronic schizophrenics. Biological Psychiatry 1986; 21: 1407–1414
   PubMed Web of Science ®Google Scholar
• Naranjo C.A., et al. Zimeldine-induced variations in alcohol intake by nondepressed heavy drinkers. Clinical Pharmacology Therapy 1984; 35: 374–381
   PubMed Web of Science ®Google Scholar
• Naranjo C.A., et al. Clinical pharmacology of serotonin-altering medications for decreasing alcohol consumption. Alcohol and Alcoholism 1993, Suppl 2: 221–229
   Google Scholar
• Norden M.J. Fluoxetine in borderline personality disorder. Progressive Neuropsychopharmacology, & Biological Psychiatry 1989; 13: 885–893
   PubMedGoogle Scholar
• Oprrz K. The effect of clonidine and related substances on voluntary ethanol consumption in rats. Drug and Alcohol Dependence 1990; 25: 43–48
   Google Scholar
• Papp M., Klimek V., Willner P. Effects of imipramine on serotonergic and betaadrenergic receptor binding in a realistic animal model of depression. Psyche/pharmacology 1994; 114: 309–314
   PubMed Web of Science ®Google Scholar
• Parsons B., Quit-Kin F.M., McGrath P.J., et al. Phenelzine, imipramine and placebo in borderline patients meeting criteria for atypical depression. Psychopharmacological Bulletin 1989; 25: 524–534
   PubMedGoogle Scholar
• Peroutka S.J. 5-HT receptor subtypes. Ann Rev Neurol 1988; 11: 45–60
   PubMed Web of Science ®Google Scholar
• Peroutka S.J., Snyder S.H. Multiple serotonin receptors. Molecular Pharmacology 1979; 16: 687–699
   PubMed Web of Science ®Google Scholar
• Ptjl H., Koppeschaar H.P., Willekens F.L., et al. Effect of serotonin reuptake inhibition by fluoxetine on body weight and spontaneous food choice in obesity. International Journal of Obesity 1991; 15: 237–242
   Google Scholar
• Porsolt R.D., Lepichon M., Jalfre M. Depression: a new animal model sensitive to antidepressant treatment. Nature 1977; 266: 730–732
   PubMed Web of Science ®Google Scholar
• Reid L.R., Wong D.T., et al. 5-Hydroxytry-tamineIA receptor in brain areas of alcohol preferring and nonpreferring rats. Fased Journal 1991; 5: A865
   Google Scholar
• Roy A., et al. Depression among alcoholics. Archives of General Psychiatry 1991; 48: 428–432
   PubMed Web of Science ®Google Scholar
• Sano H., et al. Circadian variations in plasma 5HIAA level during and after alcohol withdrawal. Acta Psychiatrica Scandinavica 1993; 87: 291–296
   PubMed Web of Science ®Google Scholar
• Schain R.J., Freedman D.X. Studies on 5hydroxyindole metabolism in autistic and other mentally retarded children. Journal of Pediatrics 1961; 58: 315–320
   PubMed Web of Science ®Google Scholar
• Schreiber R., De Vrij, et al. Ipsapirone and 80HDPAT reduce ethanol preference in rats: involvement of presynaptic 5-HTIA receptors. Psychopharmacology 1993; 112: 100–110
   Google Scholar
• Shuck M.E., Veldman S.A., Bienkowski M.J. Cloning, sequencing and phylogenetic analysis of a human 5-HTid receptor pseudogene. Gene 1993; 137: 339–344
   Google Scholar
• Siever L., Testman R.L. The serotonin system and aggressive personality. International Clinical Psychopharmacology 1993; 8(suppl 2)33–39
   PubMed Web of Science ®Google Scholar
• Soloff P.H., George A., Nathan S., et al. Progress in pharmacotherapy in borderline disorders. Archives of General Psychiatry 1986; 43: 691–697
   PubMed Web of Science ®Google Scholar
• Soloff P.H., George A., Nathan S., et al. Amitriptyline versus haloperidol in borderlines; final outcomes and predictors of response. Journal of Clinical Psychopharmacology 1989; 9: 238–246
   PubMedGoogle Scholar
• Soloff P.H., Cornelius J., George A., et al. Efficacy of phenelzine and haloperidol in borderline personality disorder. Archives of General Psychiatry 1993; 50: 377–385
   PubMed Web of Science ®Google Scholar
• Stein G. Drug treatment of personality disorders. British Journal of Psychiatry 1992; 161: 167–184
   PubMed Web of Science ®Google Scholar
• Stein D.J., Hollander E. Sexual dysfunction associated with the drug treatment of psychiatric disorders, CMS. Drugs 1994; 2: 78–86
   Google Scholar
• Stein D.J., Hollander E., Liebowitz M.R. Neurobiology of impulsivity and the impulse control disorders. Journal of Neuropsychiatry 1993; 5: 9–17
   PubMed Web of Science ®Google Scholar
• Stone M.H. Analytical orientated psychotherapy in schizotypal and borderline patients: at the border of treatability. Yak Journal of Biological Medicine 1985; 58: 275–288
   PubMed Web of Science ®Google Scholar
• Todd R.D., Ciarenello R.D. Demonstration of inter and intraspecies differences in serotonin binding sites by antibodies from an autistic child. Proceedings of the National Academy of Sciences, USA 1985; 82: 612–616
   PubMed Web of Science ®Google Scholar
• Tollefson G.D. Serotonin and alcoholism: interrelationships. Psychopathology 1989; 22: 37–48
   Google Scholar
• Traber J., Bode Greuel E., Horvath E., Jork R. Does 5-HT play a role in neuroprotection. Pharmacopsychiatry 1993; 26: 206
   Google Scholar
• Wahener G., Hielscher H., Rossberg C., Wagner H.J., Bielenberg G.W. Effects of ipsapirone on spatial and temporal changes in somatosensory evoked potentials after middle cerebral artery occlusion in the rat. Stroke 1990; 21(suppl IV)67–70
   Google Scholar
• Waldinger R.J., Gunderson J.G. Completed psychotherapies with borderline patients. American Journal of Psychotherapy 1984; 38: 190–202
   PubMed Web of Science ®Google Scholar
• Wong D.T., et al. Serotonergic and adrenergic receptors in alcohol preferring and nonpreferring rats. Journal of Neural Transmission 1988; 71: 207–218
   Google Scholar
• Wong D.T., Murphy J.M. Serotonergic mechanisms in alcohol intake. Molecular Mechanisms of Alcohol 1989; 133–146
   Google Scholar
• Wurtman J.J. Carbohydrate craving, mood changes, and obesity. Journal of Clinical Psychiatry 1988; 49: 379, Suppl
   Google Scholar