References
- Ottesen EA, Campbell WC. Ivermectin in human medicine. J Antimicrob Chemother. 1994;34:195–203
- Crump A, Omura S. Ivermectin, ‘wonder drug' from Japan: the human use perspective. Proc Jpn Acad Ser B Phys Biol Sci. 2011;87:13–28
- Stanford. Mechanism of action. Available from http://web.stanford.edu/group/parasites/ParaSites2005/Ivermectin/mechanism%20of%20action.htm. Accessed July 15, 2014
- Casas C, Paul C, Lahfa M, et al. Quantification of Demodex folliculorum by PCR in rosacea and its relationship to skin innate immune activation. Exp Dermatol. 2012;21:906–10
- Ci X, Li H, Yu Q, et al. Avermectin exerts anti-inflammatory effect by downregulating the nuclear transcription factor kappa-B and mitogen-activated protein kinase activation pathway. Fundam Clin Pharmacol. 2009;23:449–55
- Yamasaki K, Kanada K, Macleod DT, et al. TLR2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytes. J Invest Dermatol. 2011;131:688–97
- Ryu JH, Yoo JY, Kim MJ, et al. Distinct TLR-mediated pathways regulate house dust mite-induced allergic disease in the upper and lower airways. J Allergy Clin Immunol. 2013;131:549–61
- Koller B, Muller-Wiefel AS, Rupec R, et al. Chitin modulates innate immune responses of keratinocytes. PLoS One. 2011;6:e16594
- Dai X, Sayama K, Tohyama M, et al. Mite allergen is a danger signal for the skin via activation of inflammasome in keratinocytes. J Allergy Clin Immunol. 2011;127:806–14
- Holmes AD. Potential role of microorganisms in the pathogenesis of rosacea. J Am Acad Dermatol. 2013;69:1025–32
- Yan S, Ci X, Chen N, et al. Anti-inflammatory effects of ivermectin in mouse model of allergic asthma. Inflamm Res. 2011;60:589–96
- Lim LE, Vilcheze C, Ng C, et al. Anthelmintic avermectins kill Mycobacterium tuberculosis, including multidrug-resistant clinical strains. Antimicrob Agents Chemother. 2013;57:1040–6
- Pettengill MA, Lam VW, Ollawa I, et al. Ivermectin inhibits growth of Chlamydia trachomatis in epithelial cells. PLoS One. 2012;7:e48456
- Stein L, Kircik L, Fowler J, et al. Efficacy and safety of ivermectin 1% cream in treatment of papulopustular rosacea: results of two randomized, double-blind, vehicle-controlled pivotal studies. J Drugs Dermatol. 2014;13:316–23
- Taieb A, Ortonne JP, Ruzicka T, et al. Superiority of ivermectin 1% cream over metronidazole 0.75% cream in treating inflammatory lesions of rosacea: a randomized, investigator-blinded trial. Br J Dermatol. 2014. [Epub ahead of print]. DOI: 10.1111/bjd.13408