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Papers Presented at the 2nd Workshop on Radiation and Multidrug Resistance Mediated via the Tumour-Microenvironment

Co-localisation of hypoxia and perfusion markers with parameters of glucose metabolism in human squamous cell carcinoma (hSCC) xenografts

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Pages 972-980 | Received 31 Mar 2009, Accepted 26 Jul 2009, Published online: 06 Nov 2009

References

  • Baumann M, Krause M. 2009. Tumor biology's impact on clinical cure rates. In: Molls M, Vaupel P, Nieder C, Anscher MS, editors. The impact of tumor biology on cancer treatment and multidisciplinary strategies. 1st ed. Berlin: Springer. pp 323–334.
  • Bentzen SM. 2005. Theragnostic imaging for radiation oncology: dose-painting by numbers. The Lancet Oncology 6:112–117.
  • Brizel DM, Schroeder T, Scher RL, Walenta S, Clough RW, Dewhirst MW, Mueller-Klieser W. 2001. Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer. International Journal of Radiation Oncology Biology Physics 51:349–353.
  • Bruechner K, Bergmann R, Santiago A, Mosch B, Yaromina A, Hessel F, Hofheinz F, van den Hoff J, Baumann M, Beuthien-Baumann B, 2009. Comparison of [18F]FDG uptake and distribution with hypoxia and proliferation in FaDu human squamous cell carcinoma (hSCC) xenografts after single dose irradiation. International Journal of Radiation Biology 85(9).
  • Bussink J, Kaanders JH, van der Kogel AJ. 2003. Tumor hypoxia at the micro-regional level: clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers. Radiotherapy & Oncology 67:3–15.
  • DeBerardinis RJ, Mancuso A, Daikhin E, Nissim I, Yudkoff M, Wehrli S, Thompson CB. 2007. Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proceedings of the National Academy of Sciences of the United States of America 104:19345–19350.
  • Gatenby RA, Gillies RJ. 2004. Why do cancers have high aerobic glycolysis. Nature Reviews Cancer 4:891–899.
  • Gillies RJ, Raghunand N, Karczmar GS, Bhujwalla ZM. 2002. MRI of the tumor microenvironment. Journal of Magnetic Resonance Imaging 16:430–450.
  • Kaanders JH, Wijffels KI, Marres HA, Ljungkvist AS, Pop LA, van den Hoogen FJ, de Wilde PC, Bussink J, Raleigh JA, van der Kogel AJ. 2002. Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer. Cancer Research 62:7066–7074.
  • Kallinowski F, Schlenger KH, Runkel S, Kloes M, Stohrer M, Okunieff P, Vaupel P. 1989. Blood flow, metabolism, cellular microenvironment, and growth rate of human tumor xenografts. Cancer Research 49:3759–3764.
  • Krause BJ, Beck R, Souvatzoglou M, Piert M. 2006. PET and PET/CT studies of tumor tissue oxygenation. The Quarterly Journal of Nuclear Medicine and Molecular Imaging 50:28–43.
  • Matsumoto S, Hyodo F, Subramanian S, Devasahayam N, Munasinghe J, Hyodo E, Gadisetti C, Cook JA, Mitchell JB, Krishna MC. 2008. Low-field paramagnetic resonance imaging of tumor oxygenation and glycolytic activity in mice. Journal of Clinical Investigation 118:1965–1973.
  • Mueller-Klieser W, Walenta S. 1993. Geographical mapping of metabolites in biological tissue with quantitative bioluminescence and single photon imaging. The Histochemical Journal 25:407–420.
  • Plathow C, Weber WA. 2008. Tumor cell metabolism imaging. Journal of Nuclear Medicine 49(Suppl. 2):43S–63S.
  • Pugachev A, Ruan S, Carlin S, Larson SM, Campa J, Ling CC, Humm JL. 2005. Dependence of FDG uptake on tumor microenvironment. International Journal of Radiation Oncology Biology Physics 62:545–553.
  • Quennet V, Yaromina A, Zips D, Rosner A, Walenta S, Baumann M, Mueller-Klieser W. 2006. Tumor lactate content predicts for response to fractionated irradiation of human squamous cell carcinomas in nude mice. Radiotherapy & Oncology 81:130–135.
  • Rajendran JG, Mankoff DA, O'Sullivan F, Peterson LM, Schwartz DL, Conrad EU, Spence AM, Muzi M, Farwell DG, Krohn KA. 2004. Hypoxia and glucose metabolism in malignant tumors: Evaluation by [18F]fluoromisonidazole and [18F]fluorodeoxyglucose positron emission tomography imaging. Clinical Cancer Research 10:2245–2252.
  • Schroeder T, Yuan H, Viglianti BL, Peltz C, Asopa S, Vujaskovic Z, Dewhirst MW. 2005. Spatial heterogeneity and oxygen dependence of glucose consumption in R3230Ac and fibrosarcomas of the Fischer 344 rat. Cancer Research 65:5163–5171.
  • Thews O, Kelleher DK, Esser N, Kraus S, Vaupel P. 2003. Lack of association between tumor hypoxia, GLUT-1 expression and glucose uptake in experimental sarcomas. Advances in Experimental Medicine and Biology 510:57–61.
  • Vaupel P, Kallinowski F, Okunieff P. 1989. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review. Cancer Research 49:6449–6465.
  • Walenta S, Mueller-Klieser WF. 2004. Lactate: mirror and motor of tumor malignancy. Seminars in Radiation Oncology 14:267–274.
  • Walenta S, Salameh A, Lyng H, Evensen JF, Mitze M, Rofstad EK, Mueller-Klieser W. 1997. Correlation of high lactate levels in head and neck tumors with incidence of metastasis. American Journal of Pathology 150:409–415.
  • Walenta S, Schroeder T, Mueller-Klieser W. 2002. Metabolic mapping with bioluminescence: Basic and clinical relevance. Biomolecular Engineering 18:249–262.
  • Walenta S, Schroeder T, Mueller-Klieser W. 2004. Lactate in solid malignant tumors: Potential basis of a metabolic classification in clinical oncology. Current Medicinal Chemistry 11:2195–2204.
  • Walenta S, Snyder S, Haroon ZA, Braun RD, Amin K, Brizel D, Mueller-Klieser W, Chance B, Dewhirst MW. 2001. Tissue gradients of energy metabolites mirror oxygen tension gradients in a rat mammary carcinoma model. International Journal of Radiation Oncology Biology Physics 51:840–848.
  • Walenta S, Wetterling M, Lehrke M, Schwickert G, Sundfor K, Rofstad EK, Mueller-Klieser W. 2000. High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers. Cancer Research 60:916–921.
  • Yaromina A, Holscher T, Eicheler W, Rosner A, Krause M, Hessel F, Petersen C, Thames HD, Baumann M, Zips D. 2005. Does heterogeneity of pimonidazole labelling correspond to the heterogeneity of radiation-response of FaDu human squamous cell carcinoma. Radiotherapy & Oncology 76:206–212.
  • Yaromina A, Zips D, Thames HD, Eicheler W, Krause M, Rosner A, Haase M, Petersen C, Raleigh JA, Quennet V, Walenta S, Mueller-Klieser W, Baumann M. 2006. Pimonidazole labelling and response to fractionated irradiation of five human squamous cell carcinoma (hSCC) lines in nude mice: The need for a multivariate approach in biomarker studies. Radiotherapy & Oncology 81:122–129.

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