Intestinal tumours induced in Apc^Min/+ mice by X-rays and neutrons

References

• Ainsbury EA, Lloyd DC. 2010. Dose estimation software for radiation biodosimetry. Health Physics 98:290–295
   PubMed Web of Science ®Google Scholar
• Anna CH, Devereux TR. 1997. Sequence and chromosomal mapping of the mouse homolog (Madh4) of the human DPC4/MADH4 gene. Mammalian Genome 8:443–444
   PubMedGoogle Scholar
• Clark DJ, Meijne EI, Bouffler SD, Huiskamp R, Skidmore CJ, Cox R, Silver AR. 1996. Microsatellite analysis of recurrent chromosome 2 deletions in acute myeloid leukaemia induced by radiation in F1 hybrid mice. Genes, Chromosomes and Cancer 16:238–246
   PubMedGoogle Scholar
• Culling CFA. 1974. Handbook of histopathological and histochemical techniques. 3rd edn. London: Butterworths.
   Google Scholar
• Davids JA, Mos AP, de Oude A. 1969. Fast-neutron facility for biological exposures in an Argonaut reactor: Design, tissue dosimetry and neutron spectrometry. Physics in Medicine and Biology 14:573–584
   PubMedGoogle Scholar
• Degg NL, Weil MM, Edwards A, Haines J, Coster M, Moody J, Ellender M, Cox R, Silver A. 2003. Adenoma multiplicity in irradiated ApcMin mice is modified by chromosome 16 segments from BALB/c. Cancer Research 63:2361–2363
   PubMedGoogle Scholar
• Edwards AA. 1997. Relative biological effectiveness of neutrons for stochastic effects. Documents of the NRPB Volume 8, No 2. Didcot: National Radiological Protection Board;
   Google Scholar
• Edwards AA. 1999. Neutron RBE values and their relationship to judgements in radiological protection. Journal of Radiological Protection 19:93–105
   PubMedGoogle Scholar
• Ellender M, Harrison JD, Edwards AA, Bouffler SD, Cox R. 2005. Direct single gene mutational events account for radiation-induced intestinal adenoma yields in ApcMin/+ mice. Radiation Research 163:552–556
   PubMedGoogle Scholar
• Ellender M, Harrison JD, Kozlowski R, Szłuińska M, Bouffler SD, Cox R. 2006. In utero and neonatal sensitivity of ApcMin/+ mice to radiation-induced intestinal neoplasia. International Journal of Radiation Biology 82:141–151
   PubMed Web of Science ®Google Scholar
• Groden J, Thliveris A, Samowitz W, Carlson M, Gelbert L, Albertsen H, Joslyn G, Stevens J, Spirio L, Robertson M, Sargeant L, Krapcho K, Wolff E, Burt R, Hughes JP, Warrington J, McPherson J, Wasmuth J, Le Paslier D, Abderrahim H, Cohen D, Leppert M, White R. 1991. Identification and characterization of the familial adenomatous polyposis coli gene. Cell 66:589–600
   PubMed Web of Science ®Google Scholar
• Haigis KM, Caya JG, Reichelderfer M, Dove WF. 2002. Intestinal adenomas can develop with stable karyotype and stable microsatellites. Proceedings of the National Academy of Sciences of the USA 99:8927–8931
   PubMedGoogle Scholar
• Haines J, Bacher J, Coster M, Huiskamp R, Meijne E, Mancuso M, Pazzaglia S, Bouffler S. 2010. Microsatellite instability in radiation-induced murine tumours: Influence of tumour type and radiation quality. International Journal of Radiation Biology 86:555–568
   PubMed Web of Science ®Google Scholar
• Haines J, Dunford R, Moody J, Ellender M, Cox R, Silver A. 2000. Loss of heterozygosity in spontaneous and X-ray-induced intestinal tumors arising in F1 hybrid Min mice: evidence for sequential loss of Apc+ and Dpc4 in tumor development. Genes, Chromosomes and Cancer 28:387–394
   PubMedGoogle Scholar
• Haines J, Johnson V, Pack K, Suraweera N, Slijepcevic P, Cabuy E, Coster M, Ilyas M, Wilding J, Sieber O, Bodmer W, Tomlinson I, Silver A. 2005. Genetic basis of variation in adenoma multiplicity in ApcMin/+ Mom1S mice. Proceedings of the National Academy of Sciences of the USA 102:2868–2873
   PubMedGoogle Scholar
• Harrison JD, Muirhead CR. 2003. Quantitative comparisons of cancer induction in humans by internally deposited radionuclides and external radiation. International Journal of Radiation Biology 79:1–13
   PubMed Web of Science ®Google Scholar
• Ichii S, Horii A, Nakatsuru S, Furuyama J, Utsunomiya J, Nakamura Y. 1992. Inactivation of both APC alleles in an early stage of colon adenomas in a patient with familial adenomatous polyposis (FAP). Human Molecular Genetics 1:387–390
   PubMedGoogle Scholar
• Ichii S, Takeda S, Horii A, Nakatsuru S, Miyoshi Y, Emi M, Fujiwara Y, Koyama K, Furuyama J, Utsunomiya J, Nakamura Y. 1993. Detailed analysis of genetic alterations in colorectal tumours from patients with and without familial adenomatous polyposis (FAP). Oncogene 8:2399–2405
   PubMed Web of Science ®Google Scholar
• International Commission on Radiological Protection (ICRP). 1991. 1990 Recommendations of the International Commission on Radiological Protection, ICRP Publication 60. Annals of the ICRP 21:(1–3)Oxford: Pergamon Press.
   Google Scholar
• International Commission on Radiological Protection (ICRP). 2007. Recommendations of the International Commission on Radiological Protection, ICRP Publication 103. Annals of the ICRP 37:(2–4). Oxford: Elsevier Sciences.
   Google Scholar
• Ishiguro H, Furukawa Y, Daigo Y, Miyoshi Y, Nagasawa Y, Nishiwaki T, Kawasoe T, Fujita M, Satoh S, Miwa N, Fujii Y, Nakamura Y. 2000. Isolation and characterization of human NBL4, a gene involved in the ß-catenin/Tcf signalling pathway. Japan Journal of Cancer Research 91:597–603
   PubMedGoogle Scholar
• Kinzler KW, Vogelstein B. 1996. Lessons from hereditary colorectal cancer. Cell 87:159–170
   PubMed Web of Science ®Google Scholar
• Laird PW, Jackson-Grusby L, Fazeli A, Dickinson SL, Jung WE, Li E, Weinberg RA, Jaenisch R. 1995. Suppression of intestinal neoplasia by DNA hypomethylation. Cell 81:197–205
   PubMed Web of Science ®Google Scholar
• Levy DB, Smith KJ, Beazer-Barclay Y, Hamilton SR, Vogelstein B, Kinzler KW. 1994. Inactivation of both APC alleles in human and mouse tumours. Cancer Research 54:5953–5958
   PubMed Web of Science ®Google Scholar
• Little MP. 1997. Estimates of neutron relative biological effectiveness derived from the Japanese atomic bomb survivors. International Journal of Radiation Biology 72:715–726
   PubMed Web of Science ®Google Scholar
• Luongo C, Dove WF. 1996. Somatic genetic events linked to the Apc locus in intestinal adenomas of the Min mouse. Genes, Chromosomes and Cancer 17:194–198
   PubMed Web of Science ®Google Scholar
• Luongo C, Moser AR, Gledhill S, Dove WF. 1994. Loss of Apc in intestinal adenomas from Min mice. Cancer Research 54:5947–5952
   PubMed Web of Science ®Google Scholar
• Merritt AJ, Gould KA, Dove WF. 1997. Polyclonal structure of intestinal adenomas in ApcMin/+ mice with concomitant loss of Apc+ from all tumor lineages. Proceedings of the National Academy of Sciences of the USA 94:13927–13931
   PubMed Web of Science ®Google Scholar
• Moser AR, Pitot HC, Dove WF. 1990. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 247:322–324
   PubMed Web of Science ®Google Scholar
• Moser AR, Dove WF, Roth KA, Gordon JI. 1992. The Min (Multiple Intestinal Neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system. The Journal of Cell Biology 116:1517–1526
   PubMed Web of Science ®Google Scholar
• Naish SJ. 1996. Handbook of immunocytochemical staining methods. Carpinteria, CA: Dako;
   Google Scholar
• Okamoto M, Yonekawa H. 2005. Intestinal tumorigenesis in Min mice is enhanced by x-irradiation in an age-dependent manner. Journal of Radiation Research (Tokyo) 46:83–91
   PubMedGoogle Scholar
• Oshima H, Oshima M, Kobayashi M, Tsutsumi M, Taketo MM. 1997. Morphological and molecular processes of polyp formation in Apc (delta 716) knockout mice. Cancer Research 57:1644–1649
   PubMedGoogle Scholar
• Powell SM, Zilz N, Beazer-Barclay Y, Bryan TM, Hamilton SR, Thibodeau SN, Vogelstein B, Kinzler KW. 1992. APC mutations occur early during colorectal tumorigenesis. Nature 359:235–237
   PubMed Web of Science ®Google Scholar
• Sheng H, Shao J, Williams CS, Pereira MA, Taketo MM, Oshima M, Reynolds AB, Washington MK, DuBois RN, Beauchamp RD. 1998. Nuclear translocation of ß-catenin in hereditary and carcinogen-induced intestinal adenomas. Carcinogenesis 19:543–549
   PubMedGoogle Scholar
• Shoemaker AR, Moser AR, Dove WF. 1995. N-ethyl-N-nitrosurea treatment of multiple intestinal neoplasia (Min) mice: Age-related effects on the formation of intestinal adenomas, cystic crypts and epidermoid cysts. Cancer Research 55:4479–4485
   PubMed Web of Science ®Google Scholar
• Shoemaker AR, Gould KA, Luongo C, Moser AR, Dove WF. 1997. Studies of neoplasia in the Min mouse. Biochimica et Biophysica Acta 1332:F25–F48
   PubMed Web of Science ®Google Scholar
• Shrivastav M, De Haro LP, Nickoloff JA. 2008. Regulation of DNA double-strand break repair pathway choice. Cell Research 18:134–147
   PubMed Web of Science ®Google Scholar
• Silver A, Moody J, Dunford R, Clark D, Ganz S, Bulman R, Bouffler S, Finnon P, Meijne E, Huiskamp R, Cox R. 1999. Molecular mapping of chromosome 2 deletions in murine radiation-induced AML localizes a putative tumor suppressor gene to a 1.0 cM region homologous to human chromosome segment 11p11-12. Genes, Chromosomes and Cancer 24:95–104
   PubMed Web of Science ®Google Scholar
• Smits R, Kartheuser A, Jagmohan-Changur S, Leblanc V, Breukel C, de Vries A, van Kranen H, van Krieken JH, Williamson S, Edelmann W, Kucherlapati R, Khan PM, Fodde R. 1997. Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumours from Apc1638N, a mouse model for Apc driven carcinogenesis. Carcinogenesis 18:321–327
   PubMed Web of Science ®Google Scholar
• Su LK, Kinzler KW, Vogelstein B, Preisinger AC, Moser AR, Luongo C, Gould KA, Dove WF. 1992. Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science 256:668–670
   PubMed Web of Science ®Google Scholar
• Sun CX, Robb VA, Gutmann DH. 2002. Protein 4.1 tumour suppressors: Getting a FERM grip on growth regulation. Journal of Cell Science 115:3991–4000
   PubMed Web of Science ®Google Scholar
• Takeuchi K, Kawashima A, Nagafuchi A, Tsukita S. 1994. Structural diversity of band 4.1 superfamily members. Journal of Cell Science 107:1921–1928
   PubMed Web of Science ®Google Scholar
• United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR). 2000. Sources and effects of ionising radiation. Report to the General Assembly with Annexes. Vol II, United Nations, New York.
   Google Scholar
• United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR). 2006. Effects of ionising radiation. Report to the General Assembly with Annexes. Vol I, United Nations, New York.
   Google Scholar
• van der Houven van Oordt CW, Smits R, Williamson SL, Luz A, Khan PM, Fodde R, van der Eb AJ, Breuer ML. 1997. Intestinal and extra-intestinal tumor multiplicities in the Apc1638N mouse model after exposure to X-rays. Carcinogenesis 18:2197–2203
   PubMedGoogle Scholar
• van der Houven van Oordt CW, Smits R, Schouten TG, Houwing-Duistermaat JJ, Williamson SLH, Luz A, Meera Khan P, van der Eb AJ, Breuer ML, Fodde R. 1999. The genetic background modifies the spontaneous and x-ray-induced tumour spectrum in the Apc1638N mouse model. Genes, Chromosomes and Cancer 24:191–198
   PubMedGoogle Scholar
• Wasan HS, Novelli M, Bee J, Bodmer WF. 1997. Dietary fat influences on polyp phenotype in multiple intestinal neoplasia mice. Proceedings of the National Academy of Sciences of the USA 94:3308–3313
   PubMed Web of Science ®Google Scholar
• Winton DJ, Peacock JH, Ponder BA. 1989. Effect of gamma radiation at high- and low-dose rate on a novel in vivo mutation assay in mouse intestine. Mutagenesis 4:404–406
   PubMedGoogle Scholar