146
Views
11
CrossRef citations to date
0
Altmetric
INHIBITION OF UVB INDUCED OXIDATIVE DAMAGE

Inhibition of UVB-induced oxidative damage and apoptotic biochemical changes in human lymphocytes by 2,5-dihydroxy-3-undecyl-1,4-benzoquinone (embelin)

, , &
Pages 575-582 | Received 21 May 2011, Accepted 23 May 2012, Published online: 26 Jun 2012

References

  • Ahn KS, Sethi G, Agarwal BB. 2007. Embelin, an inhibitor of X chromosome-linked inhibitor of apoptosis protein, blocks nuclear factor-kappaB (NF-kB) signaling pathway leading to suppression of NF-kB regulated antiapoptotic and metastatic gene products. Molecular Pharmacology 71:209–219.
  • Alapetite C, Wachter T, Sage E, Moustacchi E. 1996. Use of the alkaline comet assay to detect DNA repair deficiencies in human fibroblasts treated to UVC, UVB, UVA and Gamma rays. International Journal of Radiation Biology 69:359–369.
  • Baliga MS, Jagetia GC, Venkatesh P, Reddy R, Ulloor JN. 2004. Radio-protective effect of abana, a polyherbal drug following total body irradiation. British Journal of Radiology 77:1027–1035.
  • Beena Joy, Lakshmi S. 2010. Antiproliferative properties of Embelia ribes. The Open Process Chemistry Journal 3:17–22.
  • Boyum A. 1968. Isolation of mononuclear cells and granulocytes from human blood. Scandinavian Journal of Clinical and Laboratory Investigation 21:77–89.
  • Brash DE, Rudolph JA, Simon JA, Lin A, McKenna GJ, Baden HP, Halperin AJ, Ponten J. 1991. A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proceedings of the National Academy of Sciences of the USA 88:10124–10128.
  • Cejkova J, Stipek S, Crkovska J, Ardan T. 2000. Changes of superoxide dismutase, catalase and glutathione peroxidase in the corneal epithelium after UVB rays: Histochemical and biochemical study. Histology and Histopathology 15:1043–1050.
  • Chitra M, Sukumar E, Suja V, Devi CS. 1994. Antitumor, anti-inflammatory and analgesic property of embelin, a plant product. Chemotherapy 40:109–113.
  • Coldiron BM. 1992. Thinning of the ozone layer: Facts and consequences. Journal of the American Academy of Dermatology 27:653–663.
  • Cross CC, Halliwell B, Borish ET, Ames WA, Saul RL, McCord JM, Harman D. 1987. Davis conference; oxygen radicals and human disease. Annals of Internal Medicine 107:526–545.
  • De Leeuw SM, Smit NPM, Veldhaven MV, Pennings EM, Pavel S, Simons JWIM, Chothorst AA. 2001. Melanin content of cultured human melanocytes and UV-induced cytotoxicity. Journal of Photochemistry and Photobiology B: Biology 61:106–113.
  • Ellman GL. 1959. Tissue sulfhydryl groups. Archives of Biochemistry and Biophysics 82:70–77.
  • Ganesan B, Perumal P, Vijaya Baskaran M, Srujana Divya G, Surya Rao S, Latha ST. 2010. Optimization of extraction conditions for embelin in Embelia ribes by UV spectrophotometry. Archives of Applied Science Research 2:49–53.
  • Halliwell B, Gutteridge MC. 1998. Free radicals in biology and medicine. 3rd ed. New York: Oxford University Press.
  • Herrlin TH, Jung K, Fuchs J. 2006. Measurement of UV generated free radicals/reactive oxygen species (ROS) in skin. Spectrochimic Acta Part A: Molecular and Biomolecular Spectroscopy 63:840–845.
  • Hoppe U, Bergemann J, Diembeck W, Ennen J, Gohla S, Harris I, Jacob J, Kielholz J, Mei W, Pollet D, Schachtschabel D, Sauermann G, Schreiner V, Stab F, Steckel F.1999. Coenzyme Q10, a cutaneous antioxidant and energizer. BioFactors 9:371–378.
  • Indian Herbal Pharmacopoeia. 2002. Mumbai, Indian Drug Manufacturers Association, India.
  • Isoherranen K, Peltola V, Laurikainen L, Punnonen J, Laihia J, Ahotupa M, Punnonen K. 1997. Regulation of copper/zinc and manganese superoxide dismutase by UV-B irradiation, oxidative stress and cytokines. Journal of Photochemistry and Photobiology B: Biology 40:288–293.
  • Jain K, Kataria S, Guruprasad KN. 2004. Effect of UV-B radiation on antioxidant enzymes and its modulation by benzoquinone and a-Tocopherol in cucumber cotyledons. Current Science 87:87–90.
  • Joshi R, Kamat JP, Mukherjee T. 2007. Free radical scavenging reactions and antioxidant activity of embelin: Biochemical and radiolytic studies. Chemico-Biological Interactions 167:125–134.
  • Kakkar P, Das B, Viswanathan PN. 1984. A modified spectrophotometric assay of superoxide dismutase. Indian Journal of Biochemistry and Biophysics 21:130–132.
  • Kawaguchi Y, Tanaka H, Okada T, Konishi H, Takahashi M, Asai J. 1996. The effects of ultraviolet A and reactive oxygen species on the mRNA expression of 72-kDa type IV collagenase and its tissue inhibitor in cultures human dermal fibroblasts. Archives of Dermatological Research 288:39–44.
  • Kim YH, Yang HE, Kim JH, Heo MY, Kim HP. 2000. Protection of the flowers of Prunus persica extract from ultraviolet B-induced damage of normal human keratinocytes. Archives of Pharmacal Research 23:396–400.
  • Koke JR, Christodoulides NJ, Chudej LL, Bittar N. 1990. Exogenous superoxide dismutase and catalase promote recovery of function in isolated heart after reginal ischemia and may be transported from capillaries into myocytes. Molecular and Cellular Biochemistry 96:97–106.
  • K pcke W, Krutmann J. 2008. Protection from sun burn with beta- carotene-meta-analysis. Photochemistry and Photobiology B Biology 84(2):284–288.
  • Kuan-Chou C, Ho-Hsing C, Wang-Sheng K, Charng-Ln W, Wen-Ta C, Chiu-Lan C. 2009. UV-induced damages eliminated by arbutin and ursolic acid in cell model of human dermal fibroblast WS-1 cells. Egyptian Dermatology Online Journal 5:1–14.
  • Kumara Swamy HM, Krishna V, Shankarmurthy K, Abdul Rahimam B, Mankani KL, Mahadevan KM, Harish BG, Raja Naika H. 2007. Wound healing activity of embelin isolated from the ethanol extract of leaves of Embelia ribes Burm. Journal of Ethnopharmacology 109:529–534.
  • Latha C. 2006. Selective extraction of embelin from Embelia ribes by hydrotropes. Separation Science and Technology 41:3721–3729.
  • Liu MC, Lin CT, Shau MD, Chen ZS, Chen MT. 1996. Studies on natural ultraviolet absorbers. Journal of Food and Drug Analysis 4:243–248.
  • Madhavan SN, Arimboor R, Arumughan C. 2011. RP-HPLC-DAD method for the estimation of embelin as marker in Embelia ribes and its polyherbal formulations. Biomedical chromatography 25:600–605.
  • Mensah AY, Sampson J, Houghton PJ, Hylands PJ, Westbrook J, Dunn M. 2001. Effects of Buddleja globosa leaf and its constituents relevant to wound healing. Journal of Ethnopharmacology 77:216–221.
  • Mhaskar M, Joshi S, Chavan B, Joglekar A, Barve N, Patwardhan, A. 2011. Status of Embelia ribes Burm f. (Vidanga), an important medicinal species of commerce from northern Western Ghats of India. Current Science 100:547–552.
  • Mori T, Doi R, Kida A, Nagai K, Kami K, Ito D, Toyoda E, Kawaguchi Y, Uemoto S. 2007. Effect of the XIAP inhibitor embelin on TRAIL-induced apoptosis of pancreatic cancer cells. Journal of Surgical Research 142:281–286.
  • Mosmann T. 1983. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assay. Journal of Immunology methods 65:55–63.
  • Nichans WG, Samuelson B. 1968. Formation of malondialdehyde from phospholipids arachidonate during microsomal lipid peroxidation. European Journal of Biochemistry 6:126–130.
  • Nikolovska-Coleska Z, Xu L, Hu Z, Tomita Y, Li P, Roller PP, Wang R, Fang X, Guo R, Zhang M, Lippman E, Yang D, Wang S. 2004. Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database. Journal of Medicinal Chemistry 47:2430–2440.
  • Pandey BN, Mishra KP. 2003. In vitro studies on radiation induced membrane oxidative damage in apoptotic death of mouse thymocytes. International Journal of Low Radiation 1:113–119.
  • Podolak I, Galanty A, Janeczko Z. 2005. Cytotoxic activity of embelin from Lysimachia punctata. Fitoterapia 76:333–335.
  • Prasad NR, Jeyanthimala K, Ramachandran S. 2009. Caffeic acid modulates ultraviolet radiation-B induced oxidative damage in human blood lymphocytes. Journal of Photochemistry and Photobiology B: Biology 95:196–203.
  • Radhakrishnan N, Gnanamani A, Mandal AB. 2011. A potential antibacterial agent, Embelin – a natural benzoquinone extracted from Embelia ribes. Biology and Medicine 3:1–7.
  • Rittie L, Fisher GJ. 2002. UV-light-induced signal cascades and skin aging. Ageing Research Reviews 1:705–720.
  • Rotruck JT, Pope AL, Ganther HE, Swanson AB. 1973. Selenium: Biochemical roles as component of glutathione Peroxidase. Science 179:588–590.
  • Singh D, Singh R, Singh P, Gupta RS. 2009. Effects of embelin on lipid peroxidation and free radical scavenging activity against liver damage in rats. Basic Clinical Pharmacology Toxicology 105:243–248.
  • Sinha KA. 1972. Colorimetric assay of catalase. Analytical biochemistry 47:389–394.
  • Sreepriya M, Bali G. 2005. Chemopreventive effects of embelin and curcumin against N-nitrosodiethylamine/Phenobarbital-induced hepatocarcinogenesis in wistar rats. Fitoterapia 76:549–555.
  • Sumino M, Sekine T, Ruangrungsi N, Igarashi K, Ikegami F. 2002. Ardisiphenols and other antioxidant principles from the fruits of Ardisia colorata. Chemical and Pharmaceutical Bulletin 50: 1484–1487.
  • Xu G, Snellman E, Bykov VJ, Jansen CT, Hemminki K. 2000. Effects of age on the formation and repair UV photoproducts in human skin in situ. Mutation Research 459:195–202.
  • Xu M, Cui J, Proksch P, Lin W, Li M. 2005. Embelin derivatives and their anticancer activity through microtubule disassembly. Planta Medica 71:944–948.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.