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Review Article

Proteomics of cancer stem cells

, &
Pages 653-658 | Received 04 Sep 2013, Accepted 26 Nov 2013, Published online: 12 May 2014

References

  • Akunuru S, Palumbo J, Zhai QJ, Zheng Y. 2011. Rac1 targeting suppresses human non-small cell lung adenocarcinoma cancer stem cell activity. PLoS One 6:e16951.
  • Andres V, Gonzalez JM. 2009. Role of A-type lamins in signaling, transcription, and chromatin organization. J Cell Biol 187:945–957.
  • Baumann M, Krause M, Hill R. 2008. Exploring the role of cancer stem cells in radioresistance. Nature Rev Cancer 8:545–554.
  • Begg AC. 2012. Predicting recurrence after radiotherapy in head and neck cancer. Semin Radiat Oncol 22:108–118.
  • Bendris N, Arsic N, Lemmers B, Blanchard JM. 2012. Cyclin A2, Rho GTPases and EMT. Small GTPases 3:225–228.
  • Butof R, Dubrovska A, Baumann M. 2013. Clinical perspectives of cancer stem cell research in radiation oncology. Radiother Oncol 108:388–96. (doi: 10.1016/j.radonc.2013.06.002).
  • De Wit M, Fijneman RJ, Verheul HM, Meijer GA, Jimenez CR. 2013. Proteomics in colorectal cancer translational research: Biomarker discovery for clinical applications. Clin Biochem 46:466–479.
  • De Wever O, De Boeck A, Maynard D, Bracke M, Hendrix A. 2013. Protein secretome analysis of evolving and responding tumor ecosystems. Curr Proteomics 10:120–135.
  • Dittmann K, Mayer C, Fehrenbacher B, Schaller M, Raju U, Milas L, Chen DJ, Kehlbach R Rodemann HP. 2005a. Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase. J Biologic Chem 280: 31182–31189.
  • Dittmann K, Mayer C, Rodemann HP. 2005b. Inhibition of radiation-induced EGFR nuclear import by C225 (Cetuximab) suppresses DNA-PK activity. Radiother Oncol 76:157–161.
  • Dodson M, Darley-Usmar V, Zhang J. 2013. Cellular metabolic and autophagic pathways: Traffic control by redox signalling. Free Rad Biol Med 63:207–221.
  • Dokmanovic M, Hirsch DS, Shen Y, Wu WJ. 2009. Rac1 contributes to trastuzumab resistance of breast cancer cells: Rac1 as a potential therapeutic target for the treatment of trastuzumab-resistant breast cancer. Molec Cancer Therapeut 8:1557–1569.
  • Estilo CL, O-charoenrat P, Talbot S, Socci ND, Carlson DL, Ghossein R, Williams T, Yonekawa Y, Ramanathan Y, Boyle JO, Kraus DH, Patel S, Shaha AR, Wong RJ, Huryn JM, Shah JP, Singh B. 2009. Oral tongue cancer gene expression profiling: Identification of novel potential prognosticators by oligonucleotide microarray analysis. BMC Cancer 9:11.
  • Gastonguay A, Berg T, Hauser AD, Schuld N, Lorimer E, Williams CL. 2012. The role of Rac1 in the regulation of NF-kappaB activity, cell proliferation, and cell migration in non-small cell lung carcinoma. Cancer Biol Ther 13:647–656.
  • Grimes C, Margolin DA, Li L. 2012. Are cancer stem cells responsible for cancer recurrence?Cell Biol: Res Ther 1:1.
  • Haddad RI, Shin DM. 2008. Recent advances in head and neck cancer. New Eng J Med 359:1143–1154.
  • Hamburger AW, Salmon SE. 1977. Primary bioassay of human tumor stem cells. Science 197:461–463.
  • Huang WC, Chen YJ, Li LY, Wei YL, Hsu SC, Tsai SL, Chiu PC, Huang WP, Wang YN, Chen CH, Chang WC, Chang WC, Chen AJ, Tsai CH, Hung MC. 2011. Nuclear translocation of epidermal growth factor receptor by Akt-dependent phosphorylation enhances breast cancer-resistant protein expression in gefitinib-resistant cells. J Biologic Chem 286:20558–20568.
  • Iwashima F, Yoshimoto T, Minami I, Sakurada M, Hirono Y, Hirata Y. 2008. Aldosterone induces superoxide generation via Rac1 activation in endothelial cells. Endocrinology 149:1009–1014.
  • Jeong HG, Cho HJ, Chang IY, Yoon SP, Jeon YJ, Chung MH, You HJ. 2002. Rac1 prevents cisplatin-induced apoptosis through down-regulation of p38 activation in NIH3T3 cells. FEBS Lett 518:129–134.
  • Kato T, Fujita Y, Nakane K, Mizutani K, Terazawa R, Ehara H, Kanimoto Y, Kojima T, Nozawa Y, Deguchi T, Ito M. 2013. CCR1/CCL5 interaction promotes invasion of taxane-resistant PC3 prostate cancer cells by increasing secretion of MMPs 2/9 and by activating ERK and Rac signalling. Cytokine 64:251–7. (doi:pii: S1043-4666(13)00587-5. 10.1016/j.cyto.2013.06.313).
  • Katz E, Sims AH, Sproul D, Caldwell H, Dixon MJ, Meehan RR, Harrison DJ. 2012. Targeting of Rac GTPases blocks the spread of intact human breast cancer. Oncotarget 3:608–619.
  • Koh MS, Moon A. 2011. Activation of H-Ras and Rac1 correlates with epidermal growth factor-induced invasion in Hs578T and MDA-MB-231 breast carcinoma cells. Biochem Biophys Res Communic 406:25–29.
  • Kong L, Schafer G, Bu H, Zhang Y, Zhang Y, Klocker H. 2012. Lamin A/C protein is overexpressed in tissue-invading prostate cancer and promotes prostate cancer cell growth, migration and invasion through the PI3K/AKT/PTEN pathway. Carcinogenesis 33:751–759.
  • Kranenburg O, Emmink BL, Knol J, van Houdt WJ, Rinkes IH, Jimenez CR. 2012. Proteomics in studying cancer stem cell biology. Expert Rev Proteomics 9:325–336.
  • Kurrey NK, Jalgaonkar SP, Joglekar AV, Ghanate AD, Chaskar PD, Doiphode RY, Bapat SA. 2009. Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells. Stem Cells 27:2059–2068.
  • Lagadec C, Vlashi E, Della DL, Meng Y, Dekmezian C, Kim K, Pajonk F. 2010. Survival and self-renewing capacity of breast cancer initiating cells during fractionated radiation treatment. Breast Cancer Res 12:R13.
  • Ma Q, Cavallin LE, Yan B, Zhu S, Duran EM, Wang H, Hale LP, Dong C, Cesarman E, Mesri EA, Goldschmidt-Clermont PJ. 2009. Antitumorigenesis of antioxidants in a transgenic Rac1 model of Kaposi's sarcoma. Proc Nat Acad Sci USA 106:8683–8688.
  • Mao P, Joshi K, Li J, Kim SH, Li P, Santana-Santos L, Luthra S, Chandran UR, Benos PV, Smith L, Wang M, Hu B, Cheng SY, Sobol RW, Nakano I. 2013. Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3. Proc Nat Acad Sci USA 110:8644–8649.
  • Mendoza-Catalan MA, Cristobal-Mondragon GR, me-Gomez J, del Valle-Flores HN, Coppe JF, Sierra-Lopez L, Romero-Hernandez MA, del Alarcon-Romero C, Illades-Aguiar B, Castaneda-Saucedo E. 2012. Nuclear expression of Rac1 in cervical premalignant lesions and cervical cancer cells. BMC Cancer 12:116.
  • Michaelson D, Abidi W, Guardavaccaro D, Zhou M, Ahearn I, Pagano M, Philips MR. 2008. Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division. J Cell Biol 181:485–496.
  • Panis C, Pizzatti L, Abdelhay E. 2013. How can proteomics reach cancer biomarkers?Curr Proteomics 10:136–149.
  • Peitzsch C, Kurth I, Kunz-Schughart L, Baumann M, Dubrovska A. 2013. Discovery of the cancer stem cell related determinants of radioresistance. Radiother Oncology 108:378–87. (doi:pii: S0167-8140(13)00278-8. 10.1016/j.radonc.2013.06.003).
  • Puhr M, Hoefer J, Schafer G, Erb HH, Oh SJ, Klocker H, Heidegger I, Neuwirt H, Culig Z. 2012. Epithelial-to-mesenchymal transition leads to docetaxel resistance in prostate cancer and is mediated by reduced expression of miR-200c and miR-205. Am J Pathol 181: 2188–2201.
  • Saini V, Shoemaker RH. 2010. Potential for therapeutic targeting of tumor stem cells. Cancer Sci 101:16–21.
  • Salvatori L, Caporuscio F, Verdina A, Starace G, Crispi S, Nicotra MR, Russo A, Calogero RA, Morgante E, Natali PG, Russo MA, Petrangeli E. 2012. Cell-to-cell signaling influences the fate of prostate cancer stem cells and their potential to generate more aggressive tumors. PLoS One 7:e31467.
  • Schaaij-Visser TB, de Wit M, Lam SW, Jimenez CR. 2013. The cancer secretome, current status and opportunities in the lung, breast and colorectal cancer context. Biochim Biophys Acta 1834:2242–58. (doi:pii: S1570-9639(13)00040-X. 10.1016/j.bbapap.2013.01.029).
  • Skvortsov S, Schafer G, Stasyk T, Fuchsberger C, Bonn GK, Bartsch G, Klocker H, Huber LA. 2011. Proteomics profiling of microdissected low- and high-grade prostate tumors identifies Lamin A as a discriminatory biomarker. J Proteome Res 10:259–268.
  • Skvortsov S, Jimenez CR, Knol JC, Eichberger P, Schiestl B, Debbage P, Skvortsova I, Lukas P. 2011. Radioresistant head and neck squamous cell carcinoma cells: Intracellular signaling, putative biomarkers for tumor recurrences and possible therapeutic targets. Radiother Oncol 101:177–182.
  • Skvortsova I, Skvortsov S, Raju U, Stasyk T, Riesterer O, Schottdorf EM, Popper BA, Schiestl B, Eichberger P, Debbage P, Neher A, Bonn GK, Huber LA, Milas L, Lukas P. 2010. Epithelial-to- mesenchymal transition and c-myc expression are the determinants of cetuximab-induced enhancement of squamous cell carcinoma radioresponse. Radiother Oncology 96:108–115.
  • Skvortsova I, Skvortsov S, Stasyk T, Raju U, Popper BA, Schiestl B, von Guggenberg E, Neher A, Bonn GK, Huber LA, Lukas P. 2008. Intracellular signaling pathways regulating radioresistance of human prostate carcinoma cells. Proteomics 8:4521–4533.
  • Sun L, Cabarcas SM, Farrar WL. 2011. Radioresistance and cancer stem cells: Survival of the fittest. J Carcinogene Mutagene S1:004. doi: 10.4172/2157-2518.S1-004
  • Theys J, Jutten B, Habets R, Paesmans K, Groot AJ, Lambin P, Wouters BG, Lammering G, Vooijs M. 2011. E-Cadherin loss associated with EMT promotes radioresistance in human tumor cells. Radiother Oncol 99:392–397.
  • Tian Q, Stepaniants SB, Mao M, Weng L, Feetham MC, Doyle MJ, Yi EC, Dai H, Thorsson V, Eng J, Goodlett D, Berger JP, Gunter B, Linseley PS, Stoughton RB, Aebersold R, Collins SJ, Hanlon WA, Hood LE. 2004. Integrated genomic and proteomic analyses of gene expression in Mammalian cells. Mollec Cellular Proteomics 3:960–969.
  • Tilghman SL, Townley I, Zhong Q, Carriere PP, Zou J, Llopis SD, Preyan LC, Williams CC, Skripnikova E, Bratton MR, Zhang Q, Wang G. 2013. Proteomic signatures of acquired letrozole resistance in breast cancer: Suppressed estrogen signaling and increased cell motility and invasiveness. Mol Cell Proteomics. 12:2440–55.
  • Wang L, Huang X, Zheng X, Wang X, Li S, Zhang L, Yang Z, Xia Z. 2013. Enrichment of prostate cancer stem-like cells from human prostate cancer cell lines by culture in serum-free medium and chemoradiotherapy. Int J Biological Sci 9:472–479.
  • Wang Y, Ngo VN, Marani M, Yang Y, Wright G, Staudt LM, Downward J. 2010. Critical role for transcriptional repressor Snail2 in transformation by oncogenic RAS in colorectal carcinoma cells. Oncogene 29:4658–4670.
  • Yalovsky S, Bloch D, Sorek N, Kost B. 2008. Regulation of membrane trafficking, cytoskeleton dynamics, and cell polarity by ROP/RAC GTPases. Plant Physiol 147:1527–1543.
  • Yoon CH, Hyun KH, Kim RK, Lee H, Lim EJ, Chung HY, An S, Park MJ, Suh Y, Kim MJ, Lee SJ. 2011. The small GTPase Rac1 is involved in the maintenance of stemness and malignancies in glioma stem-like cells. FEBS Lett 585:2331–2338.

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