Autophagic flux in glioblastoma cells

References

• Altmeyer A, Jung AC, Ignat M, Benzina S, Denis J-M, Gueulette J, Noel G, Mutter D, Bischoff P. 2010. Pharmacological enhancement of autophagy induced in a hepatocellular carcinoma cell line by high-LET radiation. Anticanc Res. 30:303–310.
   PubMed Web of Science ®Google Scholar
• Barani IJ, Larson DA. 2015. Radiation therapy of glioblastoma. Canc Treatment Res. 163:49–73.
   PubMedGoogle Scholar
• Barth S, Glick D, Macleod KF. 2010. Autophagy: assays and artifacts. J Pathol. 221:117–124.
   PubMed Web of Science ®Google Scholar
• Benzina S, Altmeyer A, Malek F, Dufour P, Denis J-M, Gueulette J, Bischoff P. 2008. High-LET radiation combined with oxaliplatin induce autophagy in U-87 glioblastoma cells. Canc Lett. 264:63–70.
   PubMed Web of Science ®Google Scholar
• Bjørkøy G, Lamark T, Pankiv S, Øvervatn A, Brech A, Johansen T. 2009. Monitoring autophagic degradation of p62/SQSTM1. Meth Enzymol. 452:181–197.
   PubMed Web of Science ®Google Scholar
• Eskelinen E-L. 2008a. Fine structure of the autophagosome. Meth Molec Biol. 445:11–28.
   PubMedGoogle Scholar
• Eskelinen E-L. 2008b. To be or not to be? Examples of incorrect identification of autophagic compartments in conventional transmission electron microscopy. Autophagy. 4:257–260.
   PubMed Web of Science ®Google Scholar
• Galavotti S, Bartesaghi S, Faccenda D, Shaked-Rabi M, Sanzone S, McEvoy A, Dinsdale D, Condorelli F, Brandner S, Campanella M, et al. 2013. The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells. Oncogene. 32:699–712.
   PubMed Web of Science ®Google Scholar
• Green DR, Galluzzi L, Kroemer G. 2014. Metabolic control of cell death. Science. 345(1250256):1–11.
   Google Scholar
• Gump JM, Thorburn A. 2014. Sorting cells for basal and induced autophagic flux by quantitative ratiometric flow cytometry. Autophagy. 10:1327–1334.
   PubMed Web of Science ®Google Scholar
• Haines IE, Miklos GLG. 2014. Bevacizumab for newly diagnosed glioblastoma. New Engl J Med. 370:2048–2049.
   PubMed Web of Science ®Google Scholar
• International Atomic Energy Agency (IAEA). 2008. The role of PET/CT in radiation treatment planning for cancer patient treatment. IAEA-TECDOC-1603.
   Google Scholar
• Jin X, Liu Y, Ye F, Liu X, Furusawa Y, Wu Q, Li F, Zheng X, Dai Z, Li Q. 2014. Role of autophagy in high linear energy transfer radiation-induced cytotoxicity to tumor cells. Canc Sci. 105:770–778.
   PubMed Web of Science ®Google Scholar
• Jinno-Oue A, Shimizu N, Hamada N, Wada S, Tanaka A, Shinagawa M, Ohtsuki T, Mori T, Saha MN, Hoque AS, et al. 2010. Irradiation with carbon ion beams induces apoptosis, autophagy, and cellular senescence in a human glioma-derived cell line. Int J Radiat Oncol Biol Phys. 76:229–241.
   PubMed Web of Science ®Google Scholar
• Kenific CM, Debnath J. 2015. Cellular and metabolic functions for autophagy in cancer cells. Trends Cell Biol. 25:37–45.
   PubMed Web of Science ®Google Scholar
• Kimura S, Noda T, Yoshimori T. 2007. Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3. Autophagy. 3:452–460.
   PubMed Web of Science ®Google Scholar
• Klionsky DJ, Abdalla FC, Abelovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, et al. 2012. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8:445–544.
   PubMed Web of Science ®Google Scholar
• Levine B. 2007. Cell biology: autophagy and cancer. Nature. 446:745–747.
   PubMed Web of Science ®Google Scholar
• Marie SKN, Mieko S, Shinjo O. 2011. Metabolism and brain cancer. Clinics. 66:33–43.
   PubMed Web of Science ®Google Scholar
• McCord AM, Jama M, Williams ES, Camphausen K, Tofilon PJ. 2009. CD133+ glioblastoma stem-like cells are radiosensitive with a defective DNA damage response compared with established cell lines. Clin Canc Res. 15:5145–5253.
   PubMed Web of Science ®Google Scholar
• Mizushima N, Yoshimori T, Levine B. 2010. Methods in mammalian autophagy research. Cell. 140:313–326.
   PubMed Web of Science ®Google Scholar
• Morgenstern JP, Land H. 1990. Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucl Acids Res. 18:3587–3596.
   PubMed Web of Science ®Google Scholar
• Paglin S, Hollister T, Delohery T, Hackett N, McMahill M, Sphicas E, Domingo D, Yahalom J. 2001. A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles. Canc Res. 61:439–444.
   PubMed Web of Science ®Google Scholar
• Palumbo S, Comincini S. 2013. Autophagy and ionizing radiation in tumors: the ‘survive or not survive’ dilemma. J Cell Physiol. 228:1–8.
   PubMed Web of Science ®Google Scholar
• Poteet E, Choudhury GR, Winters A, Li W, Ryou M-G, Liu R, Tang L, Ghorpade A, Wen Y, Yuan F, et al. 2013. Reversing the Warburg effect as a treatment for glioblastoma. J Biol Chem. 288:9153–9164.
   PubMed Web of Science ®Google Scholar
• Puissant A, Fenouille N, Auberger P. 2012. When autophagy meets cancer through p62/SQSTM1. Am J Canc Res. 2:397–413.
   PubMed Web of Science ®Google Scholar
• Schneider CA, Rasband WS, Eliceiri KW. 2012. NIH Image to ImageJ: 25 years of image analysis. Nature Meth. 9:671–675.
   PubMed Web of Science ®Google Scholar
• Sharma K, Goehe R, Beckta JM, Valerie K, Gerwitz DA. 2014. Autophagy and radiosensitization in cancer. SXCLI Jl. 13:178–191.
   Google Scholar
• Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJB, Janzer RC, Ludwin SK, Allgeier A, Fisher B, Belanger K, et al.; on behalf of the European Organisation for Research and Treatment of Cancer Brain Tumour and Radiation Oncology Groups and the National Cancer Institute of Canada Clinical Trials Group. 2009. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol. 10:459–466.
   PubMed Web of Science ®Google Scholar
• Vander Heiden MG, Cantley LC, Thompson CB. 2009. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science. 324:1029–1033.
   PubMed Web of Science ®Google Scholar
• Van Meir EG, Kikuchi T, Tada M, Li H, Diserens A-C, Wojcik BE, Huang H-JS, Friedmann T, N de Tribole N, Cavenee WK. 1994. Analysis of the p53 gene and its expression in human glioblastoma cells. Canc Res. 54:649–652.
   PubMed Web of Science ®Google Scholar
• Wang Z. 2006. Design of a boron neutron capture enhanced fast neutron therapy assembly. PhD dissertation. George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.
   Google Scholar
• Yang Z, Klionsky DJ. 2010. Mammalian autophagy: Core molecular machinery and signaling regulation. Curr Opin Cell Biol. 22:124–131.
   PubMed Web of Science ®Google Scholar
• Yasui LS, Hofer KG, Warters RL. 1985. Inhomogeneity of the nucleus to 125IUdR cytotoxicity. Radiat Res. 102:106–118.
   PubMed Web of Science ®Google Scholar
• Yasui LS. 2004. γH2AX foci induced by γ rays and 125IdU decay. Int J Radiat Biol. 80:895–903.
   PubMed Web of Science ®Google Scholar
• Yasui LS, Chen K, Wang K, Jones TP, Caldwell J, Guse D, Kassis AI. 2007. Using Hoechst 33342 to target radioactivity to the cell nucleus. Radiat Res. 167:167–175.
   PubMed Web of Science ®Google Scholar
• Yasui LS, Andorf C, Schneider L, Kroc T, Lennox A, Saroja KR. 2008. Gadolinium neutron capture in glioblastoma multiforme cells. Int J Radiat Biol. 84:1130–1139.
   PubMed Web of Science ®Google Scholar
• Yasui LS, Gladden S, Andorf C, Kroc T, Lennox A. 2011. Fast neutron induced autophagy leading to necrosis in glioblastoma multiforme. Applications of accelerators in research and industry. AIP Conf Proceed. 1336:372–382.
   Google Scholar
• Yasui LS. 2012. Molecular and cellular effect of Auger emitter, 2008–2011. Int J Radiat Biol. 88:864–870.
   PubMed Web of Science ®Google Scholar
• Yasui LS, Owens K. 2012. Necrosis is not induced by gadolinium neutron capture in glioblastoma multiforme cells. Int J Radiat Biol. 88:980–990.
   PubMed Web of Science ®Google Scholar
• Yasui LS, Johnson M, Savage H, Baker A, Baker E, Burns C. 2015. Measurement of radiation-induced autophagic flux in human brain cancer cells. Micros Microanal. 21:195–196.
   Google Scholar
• Zeng X, Overmeyer JH, Maltese WA. 2006. Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking. J Cell Sci. 119:259–270.
   PubMed Web of Science ®Google Scholar
• Zhao Y, Butler EB, Tan M. 2013. Targeting cellular metabolism to improve cancer therapeutics. Cell Death Dis. 4:e532.
   PubMed Web of Science ®Google Scholar
• Zois CE, Koukourakis MI. 2009. Radiation-induced autophagy in normal and cancer cells. Autophagy. 5:442–450.
   PubMed Web of Science ®Google Scholar